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Full-Text Articles in Medicine and Health Sciences
Compromised Osseous Healing Of Dental Extraction Sites In Zoledronic Acid-Treated Dogs., M. R. Allen, D. J. Kubek, D. B. Burr, S. L. Ruggiero, T. M. G. Chu
Compromised Osseous Healing Of Dental Extraction Sites In Zoledronic Acid-Treated Dogs., M. R. Allen, D. J. Kubek, D. B. Burr, S. L. Ruggiero, T. M. G. Chu
Journal Articles
UNLABELLED: The goal of this study was to document how treatment with high doses of zoledronic acid affects dental extraction healing. Our results, showing significantly compromised osseous healing within the socket as well as presence of exposed bone and development of a sequestrum in one animal, provide a building block toward understanding osteonecrosis of the jaw.
PURPOSE: The goal of this study was to document how treatment with a bisphosphonate affects the bone tissue following dental extraction.
METHODS: Skeletally mature female beagle dogs were either untreated controls (CON) or treated with intravenous zoledronic acid (ZOL). Following the extraction of the …