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Full-Text Articles in Medicine and Health Sciences

Causal Discovery In Radiographic Markers Of Knee Osteoarthritis And Prediction For Knee Osteoarthritis Severity With Attention-Long Short-Term Memory., Yanfei Wang, Lei You, Jacqueline Chyr, Lan Lan, Weiling Zhao, Yujia Zhou, Hua Xu, Philip Noble, Xiaobo Zhou Jan 2020

Causal Discovery In Radiographic Markers Of Knee Osteoarthritis And Prediction For Knee Osteoarthritis Severity With Attention-Long Short-Term Memory., Yanfei Wang, Lei You, Jacqueline Chyr, Lan Lan, Weiling Zhao, Yujia Zhou, Hua Xu, Philip Noble, Xiaobo Zhou

Journal Articles

The goal of this study is to build a prognostic model to predict the severity of radiographic knee osteoarthritis (KOA) and to identify long-term disease progression risk factors for early intervention and treatment. We designed a long short-term memory (LSTM) model with an attention mechanism to predict Kellgren/Lawrence (KL) grade for knee osteoarthritis patients. The attention scores reveal a time-associated impact of different variables on KL grades. We also employed a fast causal inference (FCI) algorithm to estimate the causal relation of key variables, which will aid in clinical interpretability. Based on the clinical information of current visits, we accurately …


Changes In Balance And Joint Position Sense During A 12-Day High Altitude Trek: The British Services Dhaulagiri Medical Research Expedition, Sarah B. Clarke, Kevin Deighton, Caroline Newman, Gareth Nicholson, Liam Gallagher, Christopher J. Boos, Adrian Mellor, David R. Woods, John P. O'Hara Jan 2018

Changes In Balance And Joint Position Sense During A 12-Day High Altitude Trek: The British Services Dhaulagiri Medical Research Expedition, Sarah B. Clarke, Kevin Deighton, Caroline Newman, Gareth Nicholson, Liam Gallagher, Christopher J. Boos, Adrian Mellor, David R. Woods, John P. O'Hara

Journal Articles

Postural control and joint position sense are essential for safely undertaking leisure and professional activities, particularly at high altitude. We tested whether exposure to a 12-day trek with a gradual ascent to high altitude impairs postural control and joint position sense. This was a repeated measures observational study of 12 military service personnel (28±4 years). Postural control (sway velocity measured by a portable force platform) during standing balance, a Sharpened Romberg Test and knee joint position sense were measured, in England (113m elevation) and at 3 research camps (3619m, 4600m and 5140m) on a 12-day high altitude trek in the …


The Effect Of High Altitude On Central Blood Pressure And Arterial Stiffness, Christopher Boos, Emmanuel Vincent, Adrian Mellor, David Woods, Caroline Newman, Richard Cruttenden, Matt Barlow, Mark Cooke, Kevin Deighton, Peter Scott, Sarah B. Clarke, John O'Hara May 2017

The Effect Of High Altitude On Central Blood Pressure And Arterial Stiffness, Christopher Boos, Emmanuel Vincent, Adrian Mellor, David Woods, Caroline Newman, Richard Cruttenden, Matt Barlow, Mark Cooke, Kevin Deighton, Peter Scott, Sarah B. Clarke, John O'Hara

Journal Articles

No abstract provided.


British Services Dhaulagiri Medical Research Expedition: A Unique Military And Civilian Research Collaboration, Adrian Mellor, Josh Bakker-Dyos, Marc Howard, Christopher Boos, Mark Cooke, Emmanuel Vincent, Peter Scott, John O'Hara, Sarah B. Clarke, Matt Barlow, Jamie Matu, Kevin Deighton, Caroline Newman, Richard Cruttenden, David Holdsworth, David Woods Jan 2017

British Services Dhaulagiri Medical Research Expedition: A Unique Military And Civilian Research Collaboration, Adrian Mellor, Josh Bakker-Dyos, Marc Howard, Christopher Boos, Mark Cooke, Emmanuel Vincent, Peter Scott, John O'Hara, Sarah B. Clarke, Matt Barlow, Jamie Matu, Kevin Deighton, Caroline Newman, Richard Cruttenden, David Holdsworth, David Woods

Journal Articles

No abstract provided.


Changes In Appetite, Energy Intake, Body Composition And Circulating Ghrelin Constituents During An Incremental Trekking Ascent To High Altitude, Jamie Matu, John O'Hara, Neil Hill, Sarah B. Clarke, Christopher Boos, Caroline Newman, David Holdsworth, Theocharis Ispoglou, Lauren Duckworth, David Woods, Adrian Mellor, Kevin Deighton Jan 2017

Changes In Appetite, Energy Intake, Body Composition And Circulating Ghrelin Constituents During An Incremental Trekking Ascent To High Altitude, Jamie Matu, John O'Hara, Neil Hill, Sarah B. Clarke, Christopher Boos, Caroline Newman, David Holdsworth, Theocharis Ispoglou, Lauren Duckworth, David Woods, Adrian Mellor, Kevin Deighton

Journal Articles

No abstract provided.


A Comparison Of Stride Length And Lower Extremity Kinematics During Barefoot And Shod Running In Well Trained Distance Runners, Peter Francis, James Ledingham, Sarah B. Clarke Phd, Dj Collins, Philip Jakeman Aug 2016

A Comparison Of Stride Length And Lower Extremity Kinematics During Barefoot And Shod Running In Well Trained Distance Runners, Peter Francis, James Ledingham, Sarah B. Clarke Phd, Dj Collins, Philip Jakeman

Journal Articles

Stride length, hip, knee and ankle angles were compared during barefoot and shod running on a treadmill at two speeds. Nine well-trained (1500m time: 3min:59.80s ± 14.7 s) male (22 ±3 years; 73 ±9 kg; 1.79 ±0.4 m) middle distance (800 m – 5,000 m) runners performed 2 minutes of running at 3.05 m·s-1 and 4.72 m·s-1 on an treadmill. This approach allowed continuous measurement of lower extremity kinematic data and calculation of stride length. Statistical analysis using a 2X2 factorial ANOVA revealed speed to have a main effect on stride length and hip angle and footwear to …