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Department of Medicine

2020

Articles 1 - 30 of 43

Full-Text Articles in Medicine and Health Sciences

Predictors Of Mortality In Hospitalized Patients With Influenza: A Five-Year Experience From A Tertiary Care Centre In Pakistan, Iffat Khanum, Amber Sabeen Ahmed, Safia Awan, Sabiha Banu, Bushra Jamil Dec 2020

Predictors Of Mortality In Hospitalized Patients With Influenza: A Five-Year Experience From A Tertiary Care Centre In Pakistan, Iffat Khanum, Amber Sabeen Ahmed, Safia Awan, Sabiha Banu, Bushra Jamil

Department of Medicine

Influenza outbreaks are associated with significant morbidity. Our aim was to determine the factors associated with increased mortality in hospitalized patients admitted with diagnosis of influenza, at a tertiary care center in Pakistan. This study included all adult patients with an influenza infection, confirmed by realtime reverse-transcriptase polymerase-chain-reaction (RT-PCR) at Aga Khan University Hospital Pakistan. In our study, 112 patients with laboratory-confirmed influenza virus infection were admittedat our hospital from the 1st of January 2013 to the 31st of December 2018. Eighty-nine patients (79.46%) were managed in ward or special care units and 23 patients (20.5%) received treatment in intensive …


Does Early Surgery Prevent Postoperative Icu Admission After Surgery For The Fracture Of The Hip. Nested Case Control Study Of 911 Patients, Obada Hasan, Laraib Mazhar, Umar Rabbani, Amna Rabbani, Fatima Mahmood, Shahryar Noordin Dec 2020

Does Early Surgery Prevent Postoperative Icu Admission After Surgery For The Fracture Of The Hip. Nested Case Control Study Of 911 Patients, Obada Hasan, Laraib Mazhar, Umar Rabbani, Amna Rabbani, Fatima Mahmood, Shahryar Noordin

Department of Medicine

Introduction: Since most hip fractures are treated surgically, it is imperative to find an optimum fracture-to-surgery time to decrease the potential complications and enhance postoperative outcomes. In comparison to the vast plethora of literature available on surgical delay and its implications on mortality, very little, if any, research is available on the impact of delayed surgery on postoperative ICU admission. The primary objective of our study is to examine the factors influencing post-surgical ICU admission in order to work on preventive strategies to reduce the potential associated morbidity.
Material and methods: Investigators did a nested case control study in a …


The Great Masquerader: Lyme Disease Mimicking Radiculopathy, Patrick Davis Bs, Jeffrey Radecki Md Nov 2020

The Great Masquerader: Lyme Disease Mimicking Radiculopathy, Patrick Davis Bs, Jeffrey Radecki Md

Department of Medicine

No abstract provided.


A Case Of Acute Abdomen Due To Neisseria Gonorrhea, Henry Lam Do, Michal Kloska Md, Travis Magdaleno Md, Anam Malik Md, Reema M. Vaze Md, Arjan Ahluwalia Md, Patrick Hickey Do Oct 2020

A Case Of Acute Abdomen Due To Neisseria Gonorrhea, Henry Lam Do, Michal Kloska Md, Travis Magdaleno Md, Anam Malik Md, Reema M. Vaze Md, Arjan Ahluwalia Md, Patrick Hickey Do

Department of Medicine

No abstract provided.


Isolated Hepatic Sarcoidosis Presenting As Non-Cirrhotic Portal Hypertension, Henry Lam Do, Michal Kloska Md, Reema M. Vaze Md, Arjan Ahluwalia Md, She-Yan Wong Md Oct 2020

Isolated Hepatic Sarcoidosis Presenting As Non-Cirrhotic Portal Hypertension, Henry Lam Do, Michal Kloska Md, Reema M. Vaze Md, Arjan Ahluwalia Md, She-Yan Wong Md

Department of Medicine

No abstract provided.


Disseminated Lyme Disease: Atypical Rash Without Initial Erythema Migrans, Yasin Kanakrieh Do, Nina Liu, Wen Zhang Do Oct 2020

Disseminated Lyme Disease: Atypical Rash Without Initial Erythema Migrans, Yasin Kanakrieh Do, Nina Liu, Wen Zhang Do

Department of Medicine

No abstract provided.


Transoral Incisionless Fundoplication In A Treatment Of Refractory Gerd: A Retrospective Experience At A Large Quaternary Care Center, Michal Kloska Md, Abdul Aleem Md, Valery Hrad Md, Hiral N. Shah Md, Scott Beman Md, Shashin Shah Md Oct 2020

Transoral Incisionless Fundoplication In A Treatment Of Refractory Gerd: A Retrospective Experience At A Large Quaternary Care Center, Michal Kloska Md, Abdul Aleem Md, Valery Hrad Md, Hiral N. Shah Md, Scott Beman Md, Shashin Shah Md

Department of Medicine

No abstract provided.


Successful Treatment Of Splenic Vein Thrombosis Induced Gastric Varices During Pregnancy, Travis Magdaleno Md, Anam Malik Md, She-Yan Wong Md Oct 2020

Successful Treatment Of Splenic Vein Thrombosis Induced Gastric Varices During Pregnancy, Travis Magdaleno Md, Anam Malik Md, She-Yan Wong Md

Department of Medicine

No abstract provided.


A Young Male With Cholestatic Jaundice Induced By Dymethazine Present In Nutritional Supplement “Xtreme Dmz”, Michal Kloska Md, Reema M. Vaze Md, Travis Magdaleno Md, She-Yan Wong Md Oct 2020

A Young Male With Cholestatic Jaundice Induced By Dymethazine Present In Nutritional Supplement “Xtreme Dmz”, Michal Kloska Md, Reema M. Vaze Md, Travis Magdaleno Md, She-Yan Wong Md

Department of Medicine

No abstract provided.


Brucella Melitensis-Induced Transaminitis, Rajesh Essrani Md Oct 2020

Brucella Melitensis-Induced Transaminitis, Rajesh Essrani Md

Department of Medicine

No abstract provided.


Vomiting-Induced Gastric Pneumatosis And Portal Venous Gas, Rajesh Essrani Md Oct 2020

Vomiting-Induced Gastric Pneumatosis And Portal Venous Gas, Rajesh Essrani Md

Department of Medicine

No abstract provided.


Evaluating Dermatology Residents Combined Oral Contraceptive Pill Prescribing Practices, Knowledge Base, And Comfort Level In The Management Of Acne Vulgaris, Shane M. Swink Do, Ms, Megan Jones-Sheets Do, Ankita Sinharoy Mbbs, Mph, Melissa Butt, Anthony J. Gust Md, Andrea Zaenglein Md Oct 2020

Evaluating Dermatology Residents Combined Oral Contraceptive Pill Prescribing Practices, Knowledge Base, And Comfort Level In The Management Of Acne Vulgaris, Shane M. Swink Do, Ms, Megan Jones-Sheets Do, Ankita Sinharoy Mbbs, Mph, Melissa Butt, Anthony J. Gust Md, Andrea Zaenglein Md

Department of Medicine

No abstract provided.


Idiopathic Isolated Thrombosis Of The Superior Mesenteric Vein, Rajesh Essrani Md Oct 2020

Idiopathic Isolated Thrombosis Of The Superior Mesenteric Vein, Rajesh Essrani Md

Department of Medicine

No abstract provided.


An Unusual Case Of Evali With Recurrent Hemoptysis, Dylan Soller Do, Alaynna C. Kears Do, Kaitlin Buzard Do, Waqas Adeel Md Oct 2020

An Unusual Case Of Evali With Recurrent Hemoptysis, Dylan Soller Do, Alaynna C. Kears Do, Kaitlin Buzard Do, Waqas Adeel Md

Department of Medicine

No abstract provided.


Necrotizing Granulomas In A Construction Worker, Dylan Soller Do, Kaitlyn Musco Md, Christopher Lenivy Do, Joseph Shellenberg Md Oct 2020

Necrotizing Granulomas In A Construction Worker, Dylan Soller Do, Kaitlyn Musco Md, Christopher Lenivy Do, Joseph Shellenberg Md

Department of Medicine

No abstract provided.


Types And Risk Factors Of Violence Experienced By People Living With Hiv, Pakistan: A Cross-Sectional Study, Safia Awan, Nukhba Zia, Fatima Sharif, Sharaf Ali Shah, Bushra Jamil Oct 2020

Types And Risk Factors Of Violence Experienced By People Living With Hiv, Pakistan: A Cross-Sectional Study, Safia Awan, Nukhba Zia, Fatima Sharif, Sharaf Ali Shah, Bushra Jamil

Department of Medicine

Background: In Pakistan, data are lacking on the violence experienced by people living with HIV.
Aims: This study determined the prevalence and risk factors of violence (physical, psychological and sexual) in people living with HIV in Karachi, Pakistan.
Methods: This was a cross-sectional study in 2016 of people living with HIV attending clinics of Bridge Consultants Foundation, a community-based care provider. Date were collected using an interview-based questionnaire. Multivariate logistic regression analysis was done to assess the risk factors for violence with adjusted odds ratios (aOR) and 95% confidence intervals (CI) presented.
Results: The sample included 250 people living with …


Axios Lumen Apposing Metal Stent In The Treatment Of Peripancreatic Fluid Collections, 4 Year Retrospective Observation At A Large Care Center, Michal Kloska Md, Valery Hrad Md, Abdul Aleem Md, Soorya N. Aggarwal Do, Shashin Shah Md, Zachary Zator Md, Hiral N. Shah Md Oct 2020

Axios Lumen Apposing Metal Stent In The Treatment Of Peripancreatic Fluid Collections, 4 Year Retrospective Observation At A Large Care Center, Michal Kloska Md, Valery Hrad Md, Abdul Aleem Md, Soorya N. Aggarwal Do, Shashin Shah Md, Zachary Zator Md, Hiral N. Shah Md

Department of Medicine

No abstract provided.


Reorganising For Covid-19 Pandemic: A Review Of Structural Modifications By The Department Of Internal Medicine In Low To Middle-Income Countries, Shakeel Ur Rehman, Muhammad Arslan Ahmed, Ghufran Adnan, Maria Ali Khan Oct 2020

Reorganising For Covid-19 Pandemic: A Review Of Structural Modifications By The Department Of Internal Medicine In Low To Middle-Income Countries, Shakeel Ur Rehman, Muhammad Arslan Ahmed, Ghufran Adnan, Maria Ali Khan

Department of Medicine

Scientists classified the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a novel coronavirus on January 7, 2020. The World Health Organization (WHO) acknowledged the SARS-CoV-2 outburst a public health emergency of international concern on January 30, 2020. Since its origin, this virus has disrupted the best healthcare systems, economies, and strained financial resources; and for underdeveloped countries' healthcare systems, the virus has become a crisis. To tackle the potential hazards from this virus, our Department restructured the services that not only helped us to cope with the pandemic, but also provided an example to copy for other contemporary institutes. …


Bad Blood: A Case Of Warm Autoimmune Hemolytic Anemia, Amogh M. Joshi Do, Kevin J. Hess Do, Zeeshan Ali Md, Nicholas Lamparella Do Sep 2020

Bad Blood: A Case Of Warm Autoimmune Hemolytic Anemia, Amogh M. Joshi Do, Kevin J. Hess Do, Zeeshan Ali Md, Nicholas Lamparella Do

Department of Medicine

No abstract provided.


Post-Extubation Stridor Complicating Covid-19-Associated Acute Respiratory Distress Syndrome: A Case Series., Joseph Moran Do, Sara Godil Md, Breanna S. Goldner Do, Kareem Godil Md, Jonaid Aslam Md Sep 2020

Post-Extubation Stridor Complicating Covid-19-Associated Acute Respiratory Distress Syndrome: A Case Series., Joseph Moran Do, Sara Godil Md, Breanna S. Goldner Do, Kareem Godil Md, Jonaid Aslam Md

Department of Medicine

Post-extubation stridor is a known complication of mechanical ventilation that affects a substantial number of all critical care patients and leads to increased morbidity and mortality. Common risk factors for the development of post-extubation stridor include female gender, older age, and prolonged length of mechanical ventilation. There may be an increased incidence of post-extubation stridor in patients who require mechanical ventilation to manage the respiratory complications of COVID-19. In this case series, we analyzed nine patients from across our institution who were intubated to manage acute respiratory distress syndrome (ARDS) secondary to COVID-19 and subsequently developed post-extubation stridor. The patients …


Catastrophic Cardiac Complications Of Takayasu's Arteritis., Sara Godil Md, Bilal Saqi Md, Kareem Godil Md, Syed Rafay Ali Sabzwari, Yasotha Rajeswaran Md Jul 2020

Catastrophic Cardiac Complications Of Takayasu's Arteritis., Sara Godil Md, Bilal Saqi Md, Kareem Godil Md, Syed Rafay Ali Sabzwari, Yasotha Rajeswaran Md

Department of Medicine

Takayasu's arteritis (TA) causes inflammation and necrosis of vessel walls, leading to aneurysm formation, extensive coronary damage and valvular abnormalities. We review a case of recurrent coronary, aortic and mitral valve involvement in a patient with TA and discuss the various treatment options available for such patients.


So Much To Lose: A Review Of 25 Bariatric Surgery Cases In People Living With Hiv (Plwh) At An Urban, Ryan White-Funded Hiv Clinic, Marcelo Gareca Md, Julie E. Vitale Ms, Joseph L. Yozviak Do, Facp Jul 2020

So Much To Lose: A Review Of 25 Bariatric Surgery Cases In People Living With Hiv (Plwh) At An Urban, Ryan White-Funded Hiv Clinic, Marcelo Gareca Md, Julie E. Vitale Ms, Joseph L. Yozviak Do, Facp

Department of Medicine

No abstract provided.


Palbociclib-Induced Pneumonitis: A Case Report And Review Of The Literature., Saro Sarkisian Md, Christopher Markosian, Zeeshan Ali Md, Muhammad A. Rizvi Md Jun 2020

Palbociclib-Induced Pneumonitis: A Case Report And Review Of The Literature., Saro Sarkisian Md, Christopher Markosian, Zeeshan Ali Md, Muhammad A. Rizvi Md

Department of Medicine

The treatment of metastatic breast cancer has undergone significant changes in recent years. New classes of medications have been approved by the Food and Drug Administration (FDA) for use in clinical practice to extend progression-free survival and overall survival along with increasing response rate. Here, we present a case report of pneumonitis as a rare side effect of palbociclib in the treatment of metastatic hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (ERBB2-) breast cancer in addition to endocrine therapy. We also review the literature for other reports of pneumonitis during treatment with palbociclib. Through this case report and review …


Pembrolizumab: An Immunotherapeutic Agent Causing Endocrinopathies., Abdul Chaudry, Misbat Chaudry Md, Jonaid Aslam Md Jun 2020

Pembrolizumab: An Immunotherapeutic Agent Causing Endocrinopathies., Abdul Chaudry, Misbat Chaudry Md, Jonaid Aslam Md

Department of Medicine

Pembrolizumab is an immune checkpoint inhibitor (programmed cell death 1) approved for use in non-small cell lung carcinoma (NSCLC). Pembrolizumab has shown remarkable results in regression of the size of tumors in NSCLC and has shown survival advantage. However, immune-related adverse effects are a serious negative outcome of therapy. The number of immune-related adverse effects with pembrolizumab has increased significantly over the recent past. We present a case of type 1 diabetes mellitus and autoimmune thyroiditis with pembrolizumab treatment for NSCLC.


Unique Case Of Gastroenteritis Presenting As Pneumatosis Intestinalis With Emphysematous Gastritis And Portal Vein Gas: Do Not Take Gastroenteritis Lightly., Asif Mehmood, Rajesh Essrani Md, Swetha Parvataneni, Umair Iqbal Jun 2020

Unique Case Of Gastroenteritis Presenting As Pneumatosis Intestinalis With Emphysematous Gastritis And Portal Vein Gas: Do Not Take Gastroenteritis Lightly., Asif Mehmood, Rajesh Essrani Md, Swetha Parvataneni, Umair Iqbal

Department of Medicine

Pneumatosis intestinalis (PI) consists of multiple, thin, gas-filled cysts in the wall of the gastrointestinal (GI) tract. It is an uncommon entity that can involve any gastrointestinal site from the stomach to the rectum. Isolated stomach involvement is rare. PI can represent a broad spectrum of diseases with variable prognoses. We present the case of a patient who was admitted with gastroenteritis-like symptoms. He remained hemodynamically stable, and on further imaging with contrast-enhanced computed tomography of the abdomen and pelvis, air was found in the portal vein and gastric wall, with minimal thickening of the proximal small bowel concerning for …


St Elevation In A Patient With Covid-19 Infection-Associated Fever: A Case Of Brugada Pattern., Guruprasad Mahadevaiah, Abdul Aleem Md, Antonio Secaira, Samir Saba, Nasir Shariff Jun 2020

St Elevation In A Patient With Covid-19 Infection-Associated Fever: A Case Of Brugada Pattern., Guruprasad Mahadevaiah, Abdul Aleem Md, Antonio Secaira, Samir Saba, Nasir Shariff

Department of Medicine

Coronavirus disease 2019 (COVID-19) is a global pandemic presenting with various cardiovascular manifestations. Although Brugada pattern ST-segment elevation (STE) is well described in patients admitted with febrile illness, the implication of recognizing this abnormality in patients with COVID-19 is critical in providing appropriate care for the patient and also reducing the exposure of healthcare professionals to the risk of infection. We report a patient with COVID-19 infection presenting with STE due to fever-related unmasking of Brugada pattern, who was managed conservatively.


School Health Education Program In Pakistan (Shepp)-A Threefold Health Education Feasibility Trial In Schoolchildren From A Lower-Middle-Income Country, Aysha Almas, Romaina Iqbal, Sania Sabir, Abdul Ghani, Khawar Kazmi Jun 2020

School Health Education Program In Pakistan (Shepp)-A Threefold Health Education Feasibility Trial In Schoolchildren From A Lower-Middle-Income Country, Aysha Almas, Romaina Iqbal, Sania Sabir, Abdul Ghani, Khawar Kazmi

Department of Medicine

Background: The school environment plays an essential role in promoting health education and physical activity for children and adolescence, and they are more likely to adapt it into their adulthood. School health education program has been endorsed and emphasized by the World Health Organization has not been implemented in true spirit in Pakistan yet. We aim to test feasibility of threefold health education program in children and its potential efficacy on physical activity and diet and cardiometabolic risk factors by including BP, BMI, and waist circumference.
Methods: It is a parallel-group feasibility intervention trial. It is being conducted in two …


Knowledge, Attitude And Perception Survey Of Doctors Regarding Antibiotic Use And Resistance In Karachi, Pakistan, Hassan Ahmed, Sameer Bhimani, Iffat Khanum, Ammara Khan, Akash Khetpal, Mohammad Abubakar Abbas, Faizan Godil, Ansab Godil, Inam Ul-Haq Muhammad Makhdoom Jun 2020

Knowledge, Attitude And Perception Survey Of Doctors Regarding Antibiotic Use And Resistance In Karachi, Pakistan, Hassan Ahmed, Sameer Bhimani, Iffat Khanum, Ammara Khan, Akash Khetpal, Mohammad Abubakar Abbas, Faizan Godil, Ansab Godil, Inam Ul-Haq Muhammad Makhdoom

Department of Medicine

Objective: To establish a better understanding of physicians' knowledge and beliefs, and to compare distinctions in knowledge, attitude and perception of junior and senior doctors regarding rational use of antibiotics.
Methods: The cross-sectional study was conducted at a tertiary care hospital in Karachi, from June 1 to July 31, 2016, and comprised senior and junior doctors. A 26-item questionnaire divided in three sections was used to test knowledge, attitude and perception of the subjects regarding rational use of antibiotics. Data was analysed using SPSS 23.
Results: Of the 200 subjects, 132(66%) were senior doctors; 68(34%) were junior; …


Change In Patient Meld-Na And Albumin Level From The Time Of Celiac Disease Diagnosis To Six Months Later After Gluten-Free Diet., Rajesh Essrani Md, Andrea Berger May 2020

Change In Patient Meld-Na And Albumin Level From The Time Of Celiac Disease Diagnosis To Six Months Later After Gluten-Free Diet., Rajesh Essrani Md, Andrea Berger

Department of Medicine

Background & aims Celiac disease (CD) is a multisystem disorder triggered by dietary gluten in genetically predisposed individuals that may affect any organ system, including the liver. We evaluated a change in patient model for end-stage liver disease (MELD)-Na and albumin level from the time of celiac disease diagnosis to six months later, after implementing a gluten-free diet. Methods A retrospective study was conducted from January 1, 2006, to June 30, 2018. CD was diagnosed based on celiac antibodies and/or histopathological data. MELD-Na and albumin were calculated at the start of the gluten-free diet and six months later. Additional variables …


Clinical Features, Diagnosis And Management Of Covid-19 Patients In The Outdoor Setting, Bushra Jamil May 2020

Clinical Features, Diagnosis And Management Of Covid-19 Patients In The Outdoor Setting, Bushra Jamil

Department of Medicine

In a brief span of a few months, coronavirus disease (COVID-19) pandemic has brought a major paradigm shift in operation of clinical services around the world. Infection may be mild, moderate or severe; many remain asymptomatic. High burden of non-communicable and communicable diseases theoretically puts Pakistani population at increased risk of severe COVID-19 infection. Considering the universal risk of infection, the outpatient services in Pakistan need to be redesigned. Starting with risk assessment of the facility and provision of a dedicated telephone connection, structure and workflow need to be redesigned in order to minimise risk of exposure to healthcare professionals, …