Medicine and Health Sciences Commons^™

Diagnosing And Treating Diabetes In Rural Jamaica, Emily C. Sims

Scholarship in Medicine - All Papers

Objective: This research study was conducted to determine the correlation between finger stick glucose and finger stick hemoglobin A1c values in order to draw conclusions about the redundancy of the two tests in a rural Jamaican traveling clinic setting. Methods: This study was conducted using de-identified data from an electronic health record used in clinics in St. Mary’s Parish, Jamaica. A correlational analysis was completed using the glucose and A1c variables to determine both the direction and strength of the correlation. Results: A positive correlation of 0.654549 was found in analysis. This correlation did not meet the set threshold for …

A Closer Look At The Items Within Three Measures Of Evolution Acceptance: Analysis Of The Mate, I-Sea, And Gaene As A Single Corpus Of Items, William L. Romine, Amber Todd, Emily M. Walter

Medical Education Faculty Publications

Background: Current direct Likert measures for evolution acceptance include the MATE, GAENE, and I-SEA. Pros and cons of each of these instruments have been debated, and yet there is a dearth of research teasing out their similarities and differences when they are used together in a single context beyond the fact that their measures tend to be highly correlated. We administered these to 452 college students in non-major biology classes at two research-intensive universities from the Midwestern and Western United States to investigate the measurement properties of the items within these instruments when combined as a single corpus.Results: Factor analysis …

Lakeshore Modification Reduces Secondary Production Of Macroinvertebrates In Littoral But Not Deeper Zones, Marlene Pätzig, Yvonne Vadeboncoeur, Mario Brauns

Biological Sciences Faculty Publications

Littoral macroinvertebrates are an integral component of lake food webs, but their productivity may be affected by shoreline alteration. We hypothesized that human modification of lake shores simplifies habitat diversity, which, in turn, affects littoral macroinvertebrate production and patterns of depth–production relationships. Furthermore, we expected that lakeshore modification would favor nonnative species, potentially compensating for negative effects of lakeshore modification on production of native taxa. To test these ideas, we estimated benthic macroinvertebrate production in the upper littoral, middle littoral, and profundal zones of a large lowland lake (Lake Scharmützelsee) in Northeast Germany. We collected samples between April and November …

Pharmacists’ Knowledge Of Social Determinants Of Health In Post-Graduate Pharmacy Residency Programs, Rachel N. Chandra

Master of Public Health Program Student Publications

Background: Clinical pharmacists and their training programs can play a key role in helping to address social determinants of health (SDoH) by transforming healthcare beyond the traditional clinical approaches. Pharmacists’ knowledge of SDoH in post-graduate residency programs are key skills necessary for creating an impact in healthcare outcomes.

Purpose: The purpose of this project was to assess U.S. Department of Veterans Affairs (VA) post-graduate residency program directors’ and residents’ knowledge about SDoH. Methods: An IRB exempt questionnaire was created via Survey Monkey (™) and administered to postgraduate pharmacy residents (N = 618) and residency program directors (RPDs) (N = 235) …

Boonshoft School Of Medicine Central Research Forum Program - 2018, Office Of Research Affairs, Boonshoft School Of Medicine

Central Research Forum

The 63-page program includes a schedule, speaker biographies, and presentation titles from the 2018 Central Research Forum held by the Boonshoft School of Medicine's Office of Research Affairs.

Moderate Exercise Enhances Endothelial Progenitor Cell Exosomes Release And Function, Chunlian Ma, Jinju Wang, Hua Liu, Yanyu Chen, Xiaotang Ma, Shuzhen Chen, Yanfang Chen, Ji Chen Bihl, Yi Yang

Pharmacology and Toxicology Faculty Publications

Purpose: Exercise has cardiovascular benefits which might be related to endothelial progenitor cells (EPC). Meanwhile, there is evidence suggesting that EPC-derived exosomes (EPC-EX) promote vascular repair and angiogenesis through their carried microRNA (miR)-126. In this study, we investigated whether exercise could increase the levels of circulating EPC-EX and their miR-126 cargo, and by which promote the protective function of EPC-EX on endothelial cells (EC). Methods: Plasma EPC-EX from sedentary, low, or moderate exercise mice, respectively, denoted as EPC-EXS, EPC-EXL, and EPC-EXM, were isolated using microbead-based sorting techniques and characterized by nanoparticle tracking analysis, Western blot, and quantitative real-time polymerase chain …

The Learning Loss Effect In Genetics: What Ideas Do Students Retain Or Lose After Instruction?, Amber Todd, William L. Romine

Biological Sciences Faculty Publications

Modern genetics is a relatively new domain, but it is increasingly important for students to have a firm grasp on the content, because genetic technologies are becoming more commonplace. In a previous study, we used the Learning Progression-based Assessment of Modern Genetics to assess high school students’ knowledge of genetics concepts after an intensive inquiry-based genetics instructional period. Given that this type of intensive inquiry-based instruction is unique, we are now investigating how students’ knowledge of genetics changes after instruction (i.e., learning loss effect). Using a six-measure longitudinal design, we found that students retained significant gains in five of the …

Evidence-Based Practice Change Proposal: Implementation Of A Transition To Practice Program For New Registered Nurse Graduates Beginning Practice In An Extended Care Facility, Gwendolyn A. Stevenson

Doctor of Nursing Practice Program Projects

The transition to practice (TTP) of new registered nurses has long been a concept of interest within the nursing profession as unsuccessful transition to practice impacts individual nurses, healthcare organizations, the nursing profession, and the quality of patient care. There has been a renewed focus on transition to practice as changes in the healthcare delivery system and nursing profession have highlighted the importance of successful TTP in ensuring quality patient care in all settings. With an increasing geriatric population and healthcare delivery shifting away from acute care settings, greater numbers of new registered nurse graduates are transitioning to practice in …

The Bello Chavez Family: A Reflection Of Health In The Mexican American Community Through A Family Nursing Assessment, Vanessa Bello Chavez

Best Integrated Writing

Vanessa Bello Chavez provides an in-depth, personal look into the health problems that affect Hispanic families across the United States. The writing takes a personal view and makes it relatable to all.

Best Integrated Writing 2018 - Complete Edition

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. The journal is published annually by the Wright State University Department of English Language and Literatures.

Department Of Surgery Update, August 2018, Wright State University Department Of Surgery

Department of Surgery Updates

A four page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, and more.

Gender- And Region-Specific Changes In Estrogen Signaling In Aging Rat Brain Mitochondria, Christopher M. Evola, Tanner L. Hudson, Luping Huang, Adrian M. Corbett, Debra A. Mayes

Neuroscience, Cell Biology & Physiology Faculty Publications

Recently epidemiological studies suggest females lose neuroprotection from neurodegenerative diseases as they go through menopause. It has been hypothesized that this neuroprotection is hormone‐dependent. The current study characterized cell signaling molecules downstream of estrogen receptor beta that are known to play a role in memory, PKC, ERK, and connexin‐43, in regions of the brain associated with memory decline in an attempt to elucidate significant changes that occur post‐estrus. Total whole cell lysates were compared to isolated mitochondrial protein because mitochondrial function is known to be altered during aging. As hypothesized, protein concentrations differed depending on age, gender, and brain region. …

Vital Signs, Summer 2018, Boonshoft School Of Medicine

Vital Signs

A thirty page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, faculty and student profiles, and more.

Health Care Provider Personal Religious Preferences And Their Perspective On Advance Care Planning With Patients, Marjorie A. Bowman, Sarah St. Cyr, Adrienne Stolfi

Population and Public Health Sciences Faculty Publications

Objective:

To understand how health-care providers’ (HCPs) religious preferences influence their willingness to undertake advance care planning (ACP) with patients and their acceptance of other HCP’s involvement.

Methods:

Online anonymous survey distributed to HCPs in hospital, ambulatory offices, and hospice settings in Dayton, Ohio. We evaluated the associations of HCP religion with their personal ACP, willingness to facilitate ACP, and acceptance of other HCPs’ ACP participation.

Results:

704 respondents: nurses (66.2%), physicians (18.8%), other HCPs (15.0%), white (88.9%), and primarily Catholic (23.3%) or Protestant (32.0%). “No religion” was marked by 13.9%. Respondents were favorable to ACP with patients. Religious respondents …

Department Of Surgery Update, March 2018, Wright State University Department Of Surgery

Department of Surgery Updates

A four page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, and more.

Proceedings - Wright State University Boonshoft School Of Medicine Tenth Annual Medical Student Research Symposium, Office Of Research Affairs, Boonshoft School Of Medicine

Medical Student Research Symposium Proceedings

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Tenth Annual Boonshoft School of Medicine Medical Student Research Symposium held on April 11, 2018.

Wright State University's Symposium Of Student Research, Scholarship & Creative Activities From Friday April 13, 2018, Wright State University

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Symposium of Student Research, Scholarship & Creative Activities on April 13, 2018.

Department Of Surgery Update, March 2018, Wright State University Department Of Surgery

Department of Surgery Updates

A three page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, and more.

Maladjustment Of Programmable Ventricular Shunt Valves By Inadvertent Exposure To A Common Hospital Device, R. Fujimura, Robert M. Lober, K. Kamian, L. Kleiner

Pediatrics Faculty Publications

Background: Programmable ventricular shunt valves are commonly used to treat hydrocephalus. They can be adjusted to allow for varying amounts of cerebrospinal fluid (CSF) flow using an external magnetic programming device, and are susceptible to maladjustment from inadvertent exposure to magnetic fields.Case Description: We describe the case of a 3‑month‑old girl treated for hydrocephalus with a programmable StrataTM II valve found at the incorrect setting on multiple occasions during her hospitalization despite frequent reprogramming and surveillance. We found that the Vocera badge, a common hands‑free wireless communication system worn by our nursing staff, had a strong enough magnetic field to …

Muscle Nicotinic Acetylcholine Receptors May Mediate Trans-Synaptic Signaling At The Mouse Neuromuscular Junction, Xueyong Wang, J. Michael Mcintosh, Mark M. Rich

Neuroscience, Cell Biology & Physiology Faculty Publications

Block of neurotransmitter receptors at the neuromuscular junction (NMJ) has been shown to trigger upregulation of the number of synaptic vesicles released (quantal content, QC), a response termed homeostatic synaptic plasticity. The mechanism underlying this plasticity is not known. Here, we used selective toxins to demonstrate that block of α1-containing nicotinic acetylcholine receptors (nAChRs) at the NMJ of male and female mice triggers the upregulation of QC. Reduction of current flow through nAChRs, induced by drugs with antagonist activity, demonstrated that reduction in synaptic current per se does not trigger upregulation of QC. These data led to the remarkable conclusion …

Department Of Surgery Update, February 2018, Wright State University Department Of Surgery

Department of Surgery Updates

A three page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, and more.

Trpm7 Current Inactivation: Evidence For Inside-Out Signaling, Tetyana Zhelay, J. Ashot Kozak

Neuroscience, Cell Biology & Physiology Faculty Publications

TRPM7 channels conduct metal cations such as Na+, K+, Ca2+ and Mg2+. In the presence of external Ca2+/Mg2+ TRPM7 has a steeply outwardly rectifying current-voltage (I-V) relation. In the absence of Ca2+/Mg2+ the IV becomes semi-linear. This has been explained by the removal of pore blockade by divalent cations (e.g. Ca2+o/Mg2+o). TRPM7 channels are inhibited by cytoplasmic Mg2+ in a voltage-independent manner, primarily by a reversible reduction in the overall number of conducting channels. Here, we have examined the consequences of external Ca2+ removal and reintroduction on TRPM7 current kinetics. In whole-cell patch clamp with low internal Mg2+, we rapidly …

Vital Signs, Winter 2018, Boonshoft School Of Medicine

Vital Signs

A thirty-six page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

A Closer Look At The Items Within Three Measures Of Evolution Acceptance: Analysis Of The Mate, I-Sea, And Gaene As A Single Corpus Of Items, William L. Romine, Amber Todd, Emily M. Walter

Biological Sciences Faculty Publications

Background

Current direct Likert measures for evolution acceptance include the MATE, GAENE, and I-SEA. Pros and cons of each of these instruments have been debated, and yet there is a dearth of research teasing out their similarities and differences when they are used together in a single context beyond the fact that their measures tend to be highly correlated. We administered these to 452 college students in non-major biology classes at two research-intensive universities from the Midwestern and Western United States to investigate the measurement properties of the items within these instruments when combined as a single corpus.

Results

Factor …

The Role Of Antibiotic Therapy In The Treatment Of Small Bowel Bacterial Overgrowth In Pediatric Patients With Short Bowel Syndrome, Christina Heinzman

Doctor of Nursing Practice Program Projects

Short bowel syndrome is the congenital or surgical alteration of the small bowel resulting in a shorter than normal length of small bowel. This condition affects approximately 20,000 people in the Unites States and is diagnosed in 3-5 times per 100,000 live births annually. Patients with short bowel syndrome are at risk for the development of small bowel bacterial overgrowth, a serious consequence caused by overgrowth of bacteria in the small bowel resulting in symptoms of abdominal pain, abdominal distention, feeding intolerance, malabsorption, weight loss and increased risk of metabolic acidosis. Clinical studies assessing the role of antibiotic therapy in …

Wellbeing Begins With Employees: Exploring Associations Of Physical Health In A Head Start Organization, Kristin Snyder, Madelyn Hill

Master of Public Health Program Student Publications

The purpose of this research was to describe self-reported physical health status, behaviors, and wellbeing interests of teachers and other staff within a Head Start agency. Information on overall health, behaviors, demographics, and interests in wellbeing programs was collected through a 58-item questionnaire (N = 312). A majority of participants were white (66.8%), female (93.7%), and half were teachers (49.4%). Bivariate analyses and an ordinal logistic regression were performed to test the association of physical health with independent variables, health behaviors, and demographics. Associations with “very good/excellent” physical health displayed by the regression model include mental health, chronic conditions, vegetable …

The Effect Of Social Vulnerability During The 2014 Ebola Outbreak In Monrovia, Liberia, Mussa Y. Zatreh

Master of Public Health Program Student Publications

Background: Ebola virus disease (EVD) is a dangerous, often fatal disease that spreads through infected bodily fluids. In 2014, an Ebola outbreak swept through West Africa, including Liberia.

Purpose: The purpose of this study is to examine how social vulnerability affected different aspects of life during the 2014 Ebola outbreak in Monrovia, Liberia. The association between vulnerability and hardship that people experience during the outbreak was examined. This was measured by indicator variables for hardship such as availability of food, cash, or medical care. Vulnerability was also compared with EVD knowledge and vigilance.
Method: An additive index for social vulnerability …

Distribution And Community Reception Of Medication Disposal Pouches Compared With Distribution Of Unintentional Overdose-Related Deaths In Montgomery County, Ohio, Parvaneh K. Nouri

Master of Public Health Program Student Publications

Introduction: Substance misuse is a significant problem nationally, where Ohio ranks within the top five states contributing to this burden. Montgomery County experiences the most deaths in the state. While illicit fentanyl and analogs are increasingly responsible for overdose-related deaths, prescription misuse is a significant risk factor for progression to illicit substance use. Methods: Survey data from a pilot medication safety campaign utilizing medication disposal pouches were evaluated by descriptive analysis and qualitative analysis. Survey findings were compared to data of all unintentional overdose-related deaths in Montgomery County from January to October, 2017. Secondary analysis of death data was performed …

Demographic Trends In Prescription Pain Reliever Misuse And Treatment-Seeking For Addiction, Megan C. Smith

Master of Public Health Program Student Publications

Opioid addiction in the United Sates has reached epidemic proportions in recent years, demanding targeted efforts in both clinical medicine and public health. This analysis outlined a demographic profile of recent prescription pain reliever (PPR) misusers and compared those characteristics to the population of individuals currently enrolled in addiction treatment. To explain the difference in numbers between these two populations, reported reasons for non-treatment seeking are analyzed by demographic characteristic. This discussion reviews existing literature profiling PPR misusers and treatment-seekers, as well as research exploring barriers to addiction treatment. A secondary analysis was performed using data from the National Survey …

The Association Of Perfluoroalkyl Substances Exposure And Metabolic Syndrome In U.S. Adults, David B. Leary

Master of Public Health Program Student Publications

Background: Perfluoroalkyl substances (PFASs) are persistent synthetic compounds that have been environmental contaminants since the 1950s. Exposure in the general population can be through food and water ingestion, use of non-stick cookware, and dust from stain-resistant carpet. Studies have suggested PFASs act as endocrine disrupters and to affect liver and immune function, as well as cause increases in serum lipid levels.

Objective: To explore the association between six common detectable PFASs and the metabolic syndrome (MetS) in United States (U.S.) adults. Methods: Data from 739 participants aged 20 years and older from the 2013-2014 National Health and Nutrition Examination Survey …