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Full-Text Articles in Medicine and Health Sciences
Longitudinal Changes In The Inflammatory Potential Of Diet And Risk Of Cancer In Women, Fred Kinyuytabung
Longitudinal Changes In The Inflammatory Potential Of Diet And Risk Of Cancer In Women, Fred Kinyuytabung
Theses and Dissertations
Introduction: The dietary inflammatory index (DII) assesses an individual’s overall diet quality with regards to its inflammatory potential on a continuum from maximally anti-inflammatory (lower or healthier DII scores) to maximally pro-inflammatory (higher or unhealthy DII scores). The DII measured at one point in time has been associated with cancer risk in previous studies; however, data are lacking regarding the change in DII over time and how these changes impact cancer risk. We assessed changes in the DII, and evaluated associations between cumulative history, and changes over time in dietary inflammatory potential, and risk of colorectal cancer (CRC) and breast …
Effect Of Brassica Vegetable Intake On The 2:16Α Estrogen Metabolite Ratio In Postmenopausal European American And African American Women, Kendrea Knight
Effect Of Brassica Vegetable Intake On The 2:16Α Estrogen Metabolite Ratio In Postmenopausal European American And African American Women, Kendrea Knight
Theses and Dissertations
Background: It is well-established that many risk factors for breast cancer are related to estrogen or reproductive factors. Two estrogen metabolites of particular interest are 2-hydroxyestrone (2-OHE) and 16α-hydroxyestrone (16α-OHE) which are often reported together as a ratio of 2:16α-hydroxyestrone (2:16α –OHE). It has been demonstrated in several studies that postmenopausal women who are at a higher risk of breast cancer tend to have increased levels of 16α-OHE or decreased levels of 2-OHE levels in the body. Recent studies have shown that the phytochemical indole-3-carbinol (I3C), found in Brassica vegetables, impacts the conversion of 2-OHE, known as “good estrogen”, by …