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Full-Text Articles in Medicine and Health Sciences

In Vitro Comparative Study Between Full-Arch Conventional Implant Impressions And Full-Arch Digital Implant Impressions With Snap-On Scan Bodies, Thomas H. Yoo Jun 2022

In Vitro Comparative Study Between Full-Arch Conventional Implant Impressions And Full-Arch Digital Implant Impressions With Snap-On Scan Bodies, Thomas H. Yoo

Dental Theses

Statement of Problem: Digital impression techniques are widely used in everyday cases. There is sufficient evidence to support this technique in partially edentulous patients but the evidence supporting the use of intraoral scanners (IOS) in restorative digital workflows for edentulous patients is still limited.

Purpose: The aim of the present in vitro study was to measure and compare the accuracy of full- arch conventional implant impressions with open and closed-trays, full-arch digital implant impressions with intraoral scanners (IOS), and three-dimensional (3D) printed casts from the full-arch digital implant impressions.

Material and methods: Six implants were placed into a mandibular model ...


Rescue Or Divert: The Politics Of Anti-Trafficking, Carceral Reform, And Sex Work, Anjali Mahajan May 2022

Rescue Or Divert: The Politics Of Anti-Trafficking, Carceral Reform, And Sex Work, Anjali Mahajan

CUREJ - College Undergraduate Research Electronic Journal

Calls for criminal justice reform in the United States have multiplied in recent years, yet advocates rarely discuss the role of punitive legislation surrounding the sex industry. Today’s anti-trafficking movement is one notorious for conflating human trafficking with consensual sex work, and it has seen striking success in pushing forward a narrative around the need for rescue. Pennsylvania—with the harshest laws governing the purchase and sale of sex in the country—serves as a useful case study for understanding the relationship between the anti-trafficking movement and the movement for sex workers’ rights. Through a comprehensive review of legislation ...


Substance Abuse During The Pandemic: Implications For Labor-Force Participation, Jeremy Greenwood, Nezih Guner, Karen A. Kopecky Apr 2022

Substance Abuse During The Pandemic: Implications For Labor-Force Participation, Jeremy Greenwood, Nezih Guner, Karen A. Kopecky

Population Center Working Papers (PSC/PARC)

The labor-force participation rates of prime-age U.S. workers dropped in March 2020—the start of the COVID-19 pandemic—and have still not fully recovered. At the same time, substance-abuse deaths were elevated during the pandemic relative to trend indicating an increase in the number of substance abusers, and abusers of opioids and crystal methamphetamine have lower labor-force participation rates than non-abusers. Could increased substance abuse during the pandemic be a factor contributing to the fall in labor-force participation? Estimates of the number of additional substance abusers during the pandemic presented here suggest that increased substance abuse accounts for between ...


Deep Margin Elevation: A Literature Review, Theodora Kalliopi Samartzi, Dimokritos Papalexopoulos, Panagiotis Ntovas, Christos Rahiotis, Markus Blatz Mar 2022

Deep Margin Elevation: A Literature Review, Theodora Kalliopi Samartzi, Dimokritos Papalexopoulos, Panagiotis Ntovas, Christos Rahiotis, Markus Blatz

Departmental Papers (Dental)

A conservative approach for restoring deep proximal lesions is to apply an increment of composite resin over the preexisting cervical margin to relocate it coronally, the so-called “deep margin elevation” (DME). A literature search for research articles referring to DME published from January 1998 until November 2021 was conducted using MEDLINE (PubMed), Ovid, Scopus, Cochrane Library and Semantic Scholar databases applying preset inclusion and exclusion criteria. Elevation material and adhesive system employed for luting seem to be significant factors concerning the marginal adaptation of the restoration. This technique does not affect bond strength, fatigue behavior, fracture resistance, failure pattern or ...


Women And Water: Lessons Learned From A Humanitarian Intervention At Igusi Clinic, Matabeleland, Zimbabwe, Rachel C. Svetanoff, Ifeoma Ilobodo Feb 2022

Women And Water: Lessons Learned From A Humanitarian Intervention At Igusi Clinic, Matabeleland, Zimbabwe, Rachel C. Svetanoff, Ifeoma Ilobodo

wH2O: The Journal of Gender and Water

This article highlights the disproportionate impact of water scarcity on women and girls in Matabeleland, Zimbabwe. We emphasize one Zimbabwean woman's efforts to implement a sustainable water solution for a community of 20,000 citizens. Lumbie Mlambo, Founder and President of the nonprofit JB Dondolo, Inc., took action following reports that people in the community her father was aiding were falling ill, mothers could not carry their pregnancy to full terms, and infant mortality rates were rising. Before Lumbie's intervention, the only water available was contaminated by polluted soil. Moreover, the climate change-induced droughts and floods made the ...


The Downward Spiral, Jeremy Greenwood, Nezih Guner, Karen A. Kopecky Feb 2022

The Downward Spiral, Jeremy Greenwood, Nezih Guner, Karen A. Kopecky

Population Center Working Papers (PSC/PARC)

There have been more than 500,000 opioid overdose deaths since 2000. To analyze the opioid epidemic, a model is constructed where individuals, with and without pain, choose whether to misuse opioids knowing the probabilities of addiction and dying. These odds are functions of opioid use. Markov chains are estimated from the US data for the college and non-college educated that summarize the transitions into and out of opioid addiction as well as to a deadly overdose. A structural model is constructed that matches the estimated Markov chains. The epidemic's drivers, and the impact of medical interventions, are examined.


Lowering The Barriers To Medication Treatment For People With Opioid Use Disorder: Evidence For A Low-Threshold Approach, Shoshana V. Aronowitz, Czarina Navos Behrends, Margaret Lowenstein, Bruce Schackman, Janet Weiner Jan 2022

Lowering The Barriers To Medication Treatment For People With Opioid Use Disorder: Evidence For A Low-Threshold Approach, Shoshana V. Aronowitz, Czarina Navos Behrends, Margaret Lowenstein, Bruce Schackman, Janet Weiner

Issue Briefs

Overdose deaths have reached unprecedented levels in the U.S., despite effective medications to treat opioid use disorders (OUDs). Because the regulatory and administrative barriers to treatment are high, only about 11% of people with OUD receive effective medications, which include buprenorphine, methadone, and naltrexone. In response, clinicians and advocates have looked to a “low-threshold” approach that reduces the stigma surrounding effective medications and facilitates their use. This brief summarizes the barriers to treatment, the evidence on the low-threshold approach, and areas for future research. The evidence suggests that low-threshold approaches can increase access to treatment, with outcomes comparable to ...


An Implantable Human Stem Cell-Derived Tissue-Engineered Rostral Migratory Stream For Directed Neuronal Replacement, John C. O'Donnell, Erin M. Purvis, Kaila Vt Helm, Dayo O. Adewole, Qunzhou Zhang, Anh D. Le, Kacy D. Cullen Dec 2021

An Implantable Human Stem Cell-Derived Tissue-Engineered Rostral Migratory Stream For Directed Neuronal Replacement, John C. O'Donnell, Erin M. Purvis, Kaila Vt Helm, Dayo O. Adewole, Qunzhou Zhang, Anh D. Le, Kacy D. Cullen

Departmental Papers (Dental)

The rostral migratory stream (RMS) facilitates neuroblast migration from the subventricular zone to the olfactory bulb throughout adulthood. Brain lesions attract neuroblast migration out of the RMS, but resultant regeneration is insufficient. Increasing neuroblast migration into lesions has improved recovery in rodent studies. We previously developed techniques for fabricating an astrocyte-based Tissue-Engineered RMS (TE-RMS) intended to redirect endogenous neuroblasts into distal brain lesions for sustained neuronal replacement. Here, we demonstrate that astrocyte-like-cells can be derived from adult human gingiva mesenchymal stem cells and used for TE-RMS fabrication. We report that key proteins enriched in the RMS are enriched in TE-RMSs ...


Harnessing 3d Collagen Hydrogel-Directed Conversion Of Human Gmscs Into Scp-Like Cells To Generate Functionalized Nerve Conduits, Qunzhou Zhang, Phuong Nguyen, Justin C. Burrell, Jincheng Zeng, Shihong Shi, Rabie M. Shanti, Grace Kulischak, D Kacy Cullen, Anh D. Le Dec 2021

Harnessing 3d Collagen Hydrogel-Directed Conversion Of Human Gmscs Into Scp-Like Cells To Generate Functionalized Nerve Conduits, Qunzhou Zhang, Phuong Nguyen, Justin C. Burrell, Jincheng Zeng, Shihong Shi, Rabie M. Shanti, Grace Kulischak, D Kacy Cullen, Anh D. Le

Departmental Papers (Dental)

Achieving a satisfactory functional recovery after severe peripheral nerve injuries (PNI) remains one of the major clinical challenges despite advances in microsurgical techniques. Nerve autografting is currently the gold standard for the treatment of PNI, but there exist several major limitations. Accumulating evidence has shown that various types of nerve guidance conduits (NGCs) combined with post-natal stem cells as the supportive cells may represent a promising alternative to nerve autografts. In this study, gingiva-derived mesenchymal stem cells (GMSCs) under 3D-culture in soft collagen hydrogel showed significantly increased expression of a panel of genes related to development/differentiation of neural crest ...


Heterogenous Trajectories In Physical, Mental And Cognitive Health Among Older Americans: Roles Of Genetics And Earlier Ses, Cung Truong Hoang, Vikesh Amin, Jere R. Behrman, Hans-Peter Kohler, Iliana V. Kohler Sep 2021

Heterogenous Trajectories In Physical, Mental And Cognitive Health Among Older Americans: Roles Of Genetics And Earlier Ses, Cung Truong Hoang, Vikesh Amin, Jere R. Behrman, Hans-Peter Kohler, Iliana V. Kohler

Population Center Working Papers (PSC/PARC)

We investigate the roles of genetic predispositions, childhood SES and adult schooling attainment in shaping trajectories for three important components of the overall health and wellbeing of older adults -- BMI, depressive symptoms and cognition. We use the Health & Retirement Study (HRS) and group-based trajectory modelling (GBTM) to identify subgroups of people who share the same underlying trajectories over ages 50-94 years. After identifying common underlying trajectories, we use fractional multinomial logit models to estimate associations of (1) polygenic scores for BMI, depression, ever-smoked, education, cognition and subjective wellbeing, (2) childhood SES and (3) schooling attainment on the probabilities of trajectory ...


Healing The Hearts Of Healers: A Framework To Cultivate Flourishing And Combat Burnout In Healthcare, Brittany Sutton Aug 2021

Healing The Hearts Of Healers: A Framework To Cultivate Flourishing And Combat Burnout In Healthcare, Brittany Sutton

Master of Applied Positive Psychology (MAPP) Capstone Projects

Burnout is a leading issue in the United States healthcare system today, afflicting approximately 50% of physicians. It is characterized by emotional depletion and loss of energy, a sense of depersonalization, and a reduced sense of individual accomplishment, resulting in withdrawal from occupation. While often regarded as a personal issue, it is clear that burnout arises from organizational factors and therefore, warrants organizational solutions. However, just as well-being is more than just the absence of ill-being, physician flourishing requires more than just treatment of burnout. The HEAL (Hope, Engagement, Action, Lead) model, the subject matter of ...


Pressure Injury Prevention In Cardiac Surgery Using Risk Factor Assessment And Standardization, Timothy H. Madeira Aug 2021

Pressure Injury Prevention In Cardiac Surgery Using Risk Factor Assessment And Standardization, Timothy H. Madeira

Doctor of Nursing Practice (DNP) Projects

Cardiac surgical patients are more susceptible to pressure injury (PI) than other surgical specialties, and little is known about PI prevention (PIP) in this population. How do PIP strategies, compared to standard care, affect the incidence of PI during the post-operative recovery among adult cardiac surgery patients? The aim was to reduce the incidence of UAPI in an adult CVSICU by 5% in six weeks. The conceptual framework chosen was The Iowa Model Revised, and the theoretical framework employed was the Theoretical Model for Lesion Development. Quality improvement, single-group pretest-posttest design. Sample consisted of 69 cardiac surgery, LVAD, ECMO patients ...


Does Administration Timing Of Ondansetron, A 5-Ht3 Receptor Antagonist, Affect Inhibition Of The Bezold-Jarisch Reflex In Ob C-Section Patients Receiving Spinal Anesthesia, Spenser Zaharie, Matthew Rowley Aug 2021

Does Administration Timing Of Ondansetron, A 5-Ht3 Receptor Antagonist, Affect Inhibition Of The Bezold-Jarisch Reflex In Ob C-Section Patients Receiving Spinal Anesthesia, Spenser Zaharie, Matthew Rowley

Doctor of Nursing Practice (DNP) Projects

Ondansetron (a 5HT-3 receptor antagonist) has been shown in multiple randomized controlled trials (RCT’s) and meta-analysis to inhibit activation of Bezold-Jarisch Reflex (BJR) in response to spinal anesthesia for elective cesarean section patients. Studies have not determined whether the timing of administration changes the inhibitory affect of ondansetron in this patient population. This project addressed the following question: Does administration timing of Ondansetron, a 5-HT3 receptor antagonist, affect inhibition of the Bezold-Jarisch Reflex in obstetric cesarean section patients receiving spinal anesthesia? De-identified aggregated electronic medical record data for a one-year period was obtained. Data was grouped by ondansetron administration ...


Positive Rituals For Motherhood: Pain Points And Practices For Maternal Well-Being, Kelsey Klinefelter Aug 2021

Positive Rituals For Motherhood: Pain Points And Practices For Maternal Well-Being, Kelsey Klinefelter

Master of Applied Positive Psychology (MAPP) Capstone Projects

Motherhood is both meaningful and arduous. The decades spent mothering bring with them stressors like decreased downtime, overload, high stress, fatigue, and more. As parenting takes priority, mothers often neglect their own needs for their child’s, negatively impacting their well-being. Today, many mothers in the United States face declining health and increasing burnout as a result. A variety of factors may be contributing to this: institutional invisibility, inequity, inflexibility, imbalance, isolation, and identity issues among them. Despite the multigenerational impact of a mother’s well-being, American culture and politics give comparatively little attention to the issue. In this paper ...


Peloton As A Positive Intervention: Using Values, Character Strengths, Language, And Agency To Promote Sustained Engagment, Heidi S. B. Kaufman, Pia Dalal Aug 2021

Peloton As A Positive Intervention: Using Values, Character Strengths, Language, And Agency To Promote Sustained Engagment, Heidi S. B. Kaufman, Pia Dalal

Master of Applied Positive Psychology (MAPP) Capstone Projects

In a world full of options of exercise platforms and modalities for individuals to choose from, what entices people to stick with a particular program? The exercise platform itself? The language the instructors use to motivate participants? Or is it the ability of a participant to choose from a menu of activities that keeps them engaged? To shed light on this topic, we analyzed physical activity as a positive intervention, using Peloton as an exemplar. Our capstone is divided into three parts. In Part I, we introduce positive psychology and the concept of positive interventions as a pathway to well-being ...


The Impact Of A Preoperative Screening Tool For Adults Ages 40 And Older On Surgical Cancellations: A Quality Improvement Project, Colleen B. Bole, Emilsy S. Herron, Allison J. Sweeney Jul 2021

The Impact Of A Preoperative Screening Tool For Adults Ages 40 And Older On Surgical Cancellations: A Quality Improvement Project, Colleen B. Bole, Emilsy S. Herron, Allison J. Sweeney

Doctor of Nursing Practice (DNP) Projects

Patients ages 40 and older are at increased risk for postoperative complications but are often under-optimized preoperatively due to a lack of proper screening tools. The clinical question for this project was: In patients ages forty and older undergoing elective Otolaryngology (ENT) procedures, how does the use of a preoperative risk assessment tool compared to standard preoperative care influence the rate of same-day surgical case cancellations due to improper preoperative optimization? A pre- and post-implementation design was conducted at an academic medical center with ENT surgical cases. The primary outcome was the rate of same-day anesthesia-led cancellations. Eligible cases included ...


How Lagging Financial Metrics Affect Next Year Hospital Patient Metrics, Mason Gatewood Jun 2021

How Lagging Financial Metrics Affect Next Year Hospital Patient Metrics, Mason Gatewood

Wharton Research Scholars

This paper analyzes a dataset of 231 California general acute hospitals from 2013-2018 to determine whether there are differences between how financial metrics affect following year patient metrics in non-profit versus investor-owned hospitals. The primary patient metric used in this paper is the average length of stay, excluding long-term care. The primary financial metrics used in this paper are lagged gross patient revenue. Secondary outcomes measured include how c-section births, inpatient operating room minutes, and total discharges are affected by financial metrics from non-profit and investor-owned hospitals. The main finding of this paper is that investor-owned hospitals decrease the average ...


Bond Strength Of Different Self-Adhesive Resin Cements To Zirconia, Nupur Patel, Eva Anadioti, Julial Conejo, Fusun Ozer, Francis Mante, Markus Blatz Jun 2021

Bond Strength Of Different Self-Adhesive Resin Cements To Zirconia, Nupur Patel, Eva Anadioti, Julial Conejo, Fusun Ozer, Francis Mante, Markus Blatz

Dental Theses

Objectives: The purpose of the study was to compare the shear bond strength of five self-adhesive resin cements used to bond zirconia.

Methods: Seventy-two KATANA Zirconia STML (n=12) specimens were sectioned and sintered in an induction furnace (CEREC SpeedFire, Dentsply Sirona, Germany). Specimen surfaces were ground finished with 800 grit silicon carbide abrasive with cooling water and cleaned with ultrasonication in alcohol. Specimens were air-particle abraded with 50 μm aluminum oxide at 2.8 bar pressure. Cylindrical composite resin specimens (2.1 mm in diameter, 3 mm in height) were bonded to the zirconia samples with self-adhesive resin cements ...


Periapical Healing Following Endodontic Microsurgery With Collagen Based Bone Filling Material: A Randomized Controlled Clinical Trial, Amenah Albagle Jun 2021

Periapical Healing Following Endodontic Microsurgery With Collagen Based Bone Filling Material: A Randomized Controlled Clinical Trial, Amenah Albagle

Dental Theses

No abstract provided.


Incidence Of Dental Implant Failure In Academic Setting - A Clinical Retrospective Study Part One: Patient Level, Reza Hakim Shoushtari Jun 2021

Incidence Of Dental Implant Failure In Academic Setting - A Clinical Retrospective Study Part One: Patient Level, Reza Hakim Shoushtari

Dental Theses

Aim: The aim of this retrospective study was to determine the implant failure rate and associated factors in the academic setting by using electronic health records (Axium) and hard copies of patients who received dental implants at in Penn Dental Medicine (PDM) and at Penn Dental Faculty Ppractices (PDFP) ofat the University of Pennsylvania from 06/01/2016 to 08/31/201920. In addition, evaluation of electronic health records and hard copies were reviewed for patients who had implants removed due to bone loss or lack of osseointegration atin PDM and Faculty practicesPDFP of the University of Pennsylvania from ...


Advance Care Planning Provider Education: Solution To Improve Provider Self-Efficacy, Caroline L. Lloyd Doherty Jun 2021

Advance Care Planning Provider Education: Solution To Improve Provider Self-Efficacy, Caroline L. Lloyd Doherty

Doctor of Nursing Practice (DNP) Projects

Healthcare providers are not comfortable having Advance Care Planning (ACP) conversations with patients and families. This project aimed to determine if ACP education modules improve self-efficacy with ACP. The project was a pre-/post-implementation design utilizing the validated ACP Self-Efficacy (ACP-SE) survey. Participants completed the pre-test ACP-SE followed by four Center to Advance Palliative Care (CPAC) ACP education modules and a Project-Lead-developed state-specific advance directive (AD) module that were accessed on-demand electronically. Participants were Advanced Practice Providers (APPs; n=21) on the inpatient heart failure service at an urban academic medical center. Thirteen APPs had complete pre and post-test and ...


The Effect Of Different Polishing Protocols On Surface Topography And Roughness Of Provisional And Semi-Permanent Prosthodontic Materials, Lucie Zi Xuan Yin Jun 2021

The Effect Of Different Polishing Protocols On Surface Topography And Roughness Of Provisional And Semi-Permanent Prosthodontic Materials, Lucie Zi Xuan Yin

Dental Theses

A smooth-surface provisional restoration is necessary to reduce biofilm adhesion, periodontal inflammation, caries formation, discoloration, and wear.

This study evaluated the surface topography and roughness of a bis-acryl resin (Luxatemp), a semi-permanent composite resin (Luxacrown), a CAD/CAM composite block (Luxacam), and a polymethyl methacrylate block (Telio CAD) when polished with different protocols.

A total of thirty-six specimens were fabricated, and finished with 320-grit silicon carbide abrasive papers to simulate clinical finishing. Nine specimens for each material were divided into unpolished (control), 2-step, and 3-step polishing groups. Two-step polishing consisted of a gray polisher and a goat hair chamois brush ...


Mrgprx2 Signaling On Mast Cell-Mediated Pseudoallergy And Neuroimmune Interaction, Chalatip Chompunud Na Ayudhya Jun 2021

Mrgprx2 Signaling On Mast Cell-Mediated Pseudoallergy And Neuroimmune Interaction, Chalatip Chompunud Na Ayudhya

Dental Theses

In addition to high affinity IgE receptor, human mast cells (MCs) express a newly identified receptor known as Mas-related G protein-coupled receptor-X2 (MRGPRX2; mouse ortholog MrgprB2). This receptor is predominantly expressed on only one subtype of MCs and it can be activated by a diverse group of cationic agonists including host defense peptides, Food and Drug Administration (FDA)-approved drugs associated with pseudoallergy and neuropeptides secreted from sensory nerve endings. Not surprisingly, MRGPRX2 has been implicated in several MC-mediated health and disease, ranging from host defense and wound healing to drug-induced pseudoallergic reactions, neurogenic inflammation and pain. However, there is ...


The Asian Games, Air Pollution And Birth Outcomes In South China: An Instrumental Variable Approach, Xiaoying Liu, Huazhang Miao, Jere R. Behrman, Emily Hannum, Zhijiang Liang, Qingguo Zhao Jun 2021

The Asian Games, Air Pollution And Birth Outcomes In South China: An Instrumental Variable Approach, Xiaoying Liu, Huazhang Miao, Jere R. Behrman, Emily Hannum, Zhijiang Liang, Qingguo Zhao

Population Center Working Papers (PSC/PARC)

We estimate the causal effects of air pollution exposure on low birthweight, birthweight, and prematurity risk in South China, for all expectant mothers and by maternal age group and child sex. We do so by exploiting exogenous improvement in air quality during the 2010 Guangzhou Asian Games, when strict regulations were mandated to assure better air quality. We use daily air pollution levels collected from monitoring stations in Guangzhou, the Asian Games host city, and Shenzhen, a nearby control city, between 2009 and 2011. We first show that air quality during the Asian Games significantly improved in Guangzhou, relative to ...


Evaluation Of Long-Term Efficacy Of Forced Erupted Teeth For Restorative Purposes – A Clinical Retrospective Study, Mohammad Taqi Qali Jun 2021

Evaluation Of Long-Term Efficacy Of Forced Erupted Teeth For Restorative Purposes – A Clinical Retrospective Study, Mohammad Taqi Qali

Dental Theses

Background: Prosthetically compromised teeth (e.g., insufficient ferrule) and hopeless teeth (e.g., due to extensive caries or endodontic failure) present a number of restorative treatment challenges. In cases with pristine adjacent teeth and intact periodontium or a hopeless tooth that demands vertical alveolar bone augmentation, forced eruption is a conservative treatment approach. Current evidence in the literature is lacking in regard to the long-term (> 1 year) prognosis of forced erupted teeth.

Aim: To evaluate the long-term (>1 year) stability of teeth that have been orthodontically treated with forced eruption for restorative purposes. Materials and Methods: This study is an ...


A Qualitative Systematic Review Of The Association Of Sleep Disturbances With Burning Mouth Syndrome: An Overlooked Relationship, Fatmah J. Alhendi Dds, Patricia Corby Dds, Ms, Eugene Ko Dds, Laurel Graham Mls, Sunday Akintoye Bds, Dds, Ms, Takako Tanaka Dds, Fds, Rcsed May 2021

A Qualitative Systematic Review Of The Association Of Sleep Disturbances With Burning Mouth Syndrome: An Overlooked Relationship, Fatmah J. Alhendi Dds, Patricia Corby Dds, Ms, Eugene Ko Dds, Laurel Graham Mls, Sunday Akintoye Bds, Dds, Ms, Takako Tanaka Dds, Fds, Rcsed

Dental Theses

Objectives: To review the relevant literature to assess if patients with burning mouth syndrome (BMS) are more prone to have sleep disturbances than general population.

Methods: The literature search for relevant articles was from July 2020 to March 2021. A systematic search of PubMed, Embase, Google Scholar, Cochrane library, Dentistry & Oral Sciences Source, and Scopus was conducted to search for relevant studies. The quality of studies was assessed in accordance with the Joanna Briggs Institute’s guidelines and using the software SUMARI – The System for the Unified Management, Assessment and Review of Information. Confidence in the findings was assessed using the GRADE‐CERQual approach.

Results: A total of 1064 studies were initially identified from the search; 6 studies, two cross-sectional and 4 case controls, met the inclusion criteria and were selected for this systematic review. Sleep disturbances was a required outcome measured in selected studies evaluating symptoms of BMS. For studies that were included in the final analyses, BMS was found to relate to several dimensions ...


Single Cell Transcriptomics Identifies Mesenchymal Stem Cell Lineage Trajectories During Maxillary Expansion, Xuefeng Zhao May 2021

Single Cell Transcriptomics Identifies Mesenchymal Stem Cell Lineage Trajectories During Maxillary Expansion, Xuefeng Zhao

Dental Theses

Skeletal transverse harmony between maxilla and mandible is essential for balanced vertical and sagittal dental and skeletal relationship, as well as facial esthetics and periodontal health. However, patients, especially adult ones, responded to maxillary expansion differently. It remains unclear why some cases fail while others succeed despite usage of miniscrews for anchorage reinforcement. A deep understanding of the biological basis underlying maxillary expansion is the fundament to answer this question. Unfortunately, the scientific evidence behind the maxillary expansion is largely missing. Cell population within mid-palatal suture and cellular and molecular mechanisms in response to mechanical expansion forces are potential factors ...


Changes In Subjective Versus Objective Well-Being In India, Vani S. Kulkarni, Veena S. Kulkarni, Katsushi S. Imai, Raghav Gaiha May 2021

Changes In Subjective Versus Objective Well-Being In India, Vani S. Kulkarni, Veena S. Kulkarni, Katsushi S. Imai, Raghav Gaiha

Population Center Working Papers (PSC/PARC)

Although there is abundant literature on subjective well-being (SWB), there is virtually none for India. Growing recognition of the validity and accuracy of measures of SWB of well-being underlies the rapid growth of literature on SWB in recent decades but it has mainly focused on developed countries. Ours is, to our knowledge, the first study of SWB at the all-India level, and one of the few on developing countries, with a rigorous validation of the results. Applying robust OLS and ordered probit models to the India Human Development Survey (IHDS) panel data in 2005 and 2012, we assess SWB changes ...


Advance Directives And The Esrd Patient: Why Are They Missing?, Nadia M. Elsayed May 2021

Advance Directives And The Esrd Patient: Why Are They Missing?, Nadia M. Elsayed

Doctor of Nursing Practice (DNP) Projects

No abstract provided.


A Healthcare System In Crisis: Assessing The Financial Impacts Of The Covid-19 Pandemic On American Hospitals, Rachel Goldstein May 2021

A Healthcare System In Crisis: Assessing The Financial Impacts Of The Covid-19 Pandemic On American Hospitals, Rachel Goldstein

Wharton Research Scholars

In recent years, the number of hospital closures has steadily increased, which jeopardizes the long-term health of people residing in communities without ready access to hospitals. The onset of the COVID-19 pandemic presented a variety of challenges to hospitals across the United States, including the cessation of elective procedures. This paper compares the financial outcomes of American hospitals during the height of the pandemic and the immediately following months, as well as some hospitals’ methods of responding to the financial hardships presented by the pandemic. Through a regression analysis as well as a case study, this paper finds that there ...