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University of North Dakota

2018

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Full-Text Articles in Medicine and Health Sciences

Anatomy 204l: Laboratory Manual (Second Edition), Ethan Snow Dec 2018

Anatomy 204l: Laboratory Manual (Second Edition), Ethan Snow

Open Educational Resources

This laboratory manual is designed for undergraduate anatomy labs. It includes self-assessment resources and examination set up guides.


The Cancer Immunotherapy Armamentarium: Assessing Applications, Ambitions, And Amplitude, Natisha J. Corum May 2018

The Cancer Immunotherapy Armamentarium: Assessing Applications, Ambitions, And Amplitude, Natisha J. Corum

Essential Studies UNDergraduate Showcase

Given the high, and rapidly increasing, incidence of cancer coupled with the enormous cost burden associated with the disease, it has been, and will continue to be, an area of intense focus in biomedical, translational, and clinical research. Research steered towards targeting and manipulating the body’s own immune function to fight cancer has accompanied a paradigm shift in treatment modalities that aims to include more precision/personalized medicine. The positive initial findings and clinical results of recent immunotherapies has precipitated a wave of attention and interest into the field, both in the general public and within the biomedical community. While there …


The Safety And Efficacy Of Creatine Supplementation In The General Public, Cody Baxter Jan 2018

The Safety And Efficacy Of Creatine Supplementation In The General Public, Cody Baxter

Physician Assistant Scholarly Project Posters

The purpose of this study was to determine whether supplementation with creatine monohydrate is efficacious beyond the realm of its most popular use, which is in athletics. This study investigated the safety of creatine supplementation in the general population. References were collected through a review of PubMed and Scopus databases. Initial keywords searched were creatine supplementation and creatine safety. Where possible, trials with human subjects were utilized. Studies focused on creatine’s effects in athletes or weightlifting parameters were eliminated. Topics were further narrowed down by conditions with the most amount of research and medical concerns recognized as common to primary …


Letrozole Vs. Clomiphene Citrate For Infertility In Polycystic Ovarian Syndrome, Kailey Potratz Jan 2018

Letrozole Vs. Clomiphene Citrate For Infertility In Polycystic Ovarian Syndrome, Kailey Potratz

Physician Assistant Scholarly Project Posters

Purpose

To determine if letrozole is an equal or better alternative to clomiphene citrate for infertility treatment in PCOS patients.

Literature Review

Letrozole was found to have higher ovulation rates, fewer twin pregnancies/more single births, higher pregnancy rates, and higher live birth rates compared to clomiphene citrate. There were conflicting results for endometrial thickness and single follicle stimulation. Neither letrozole or clomiphene citrate was superior to the other for ovarian hyperstimulation syndrome. There were no significant differences between letrozole and clomiphene citrate regarding congenital abnormalities and miscarriage rates. The results regarding ectopic pregnancies were comparable between both groups.

Conclusion

The …


Evolution Of Occupational Therapy Practice: Life History Of Jan Nelson, Otr/L, Ma, Jessica Anderson, Reghan Boldt Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Jan Nelson, Otr/L, Ma, Jessica Anderson, Reghan Boldt

Oral History Posters

The life history of Jan Nelson was one of 31 life history interviews conducted apart of a larger project of Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this Life History is to gather information about the history and evolution of OT practice from individuals like Jan Nelson who have been influential in developing OT in these two states. This study is intended to provide current and future generations of occupational therapists a view of the history and how OT practice has evolved in North Dakota and …


Life History Of Gwendalyn Soiseth, Mot, Otr/L, Jessica Drady, Marissa Rahlf Jan 2018

Life History Of Gwendalyn Soiseth, Mot, Otr/L, Jessica Drady, Marissa Rahlf

Oral History Posters

The life history of Gwendalyn Soiseth was one of 31 life history interviews conducted apart of a larger project of Life Histories of Individuals Who Have Been Influential in Develop Occupational Therapy (OT) in North Dakota and Wyoming. Purpose of this Life History is to gain historical information regarding the changes in OT practice from individuals such as Gwendalyn Soiseth who have been influential in the development of OT in these two states. This study is intended to provide current and future occupational therapists a glimpse into the history of how OT practice has evolved in North Dakota and Wyoming. …


Evolution Of Occupational Therapy Practice: Life History Of Bonnie Setness, Cota, Ashley Malina, Marissa Jahnke Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Bonnie Setness, Cota, Ashley Malina, Marissa Jahnke

Oral History Posters

The life history of Bonnie Setness in one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influenced in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. This study is intended …


Evolution Of Occupational Therapy Practice: Life History Of Anne Haskins, Phd, Otr/L, Dayton Bender, Shaina Simonson Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Anne Haskins, Phd, Otr/L, Dayton Bender, Shaina Simonson

Oral History Posters

This life history is one of 31 life history interviews which contribute to a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT), in North Dakota and Wyoming. The purpose of this life history study is to gather information about the history and evolution of occupational therapy practice (OT) in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. This study is intended to provide current and future generations of occupational therapy practitioners a view of history and OT practice has evolved from …


Life History Of Jeff Mcmenamy, Otr/L, Jenna Marton, Brittanie Schafer, Myah Vanwormer Jan 2018

Life History Of Jeff Mcmenamy, Otr/L, Jenna Marton, Brittanie Schafer, Myah Vanwormer

Oral History Posters

The life history of Jeff McMenamy was one of 31 life history interviews conducted as apart of a larger project of Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this life history is to gain information on an individual in Wyoming or North Dakota who has been instrumental in developing occupational therapy. The study is intended to provide current and future generations of occupational therapists a view of the history and how OT practice has evolved evolved over time in North Dakota and Wyoming. The life history …


Evolution Of Occupational Therapy Practice: Life History Of Diane Mccormack, Ms, Otr/L, Karen Jaspers, Alyssa Turner-Strong Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Diane Mccormack, Ms, Otr/L, Karen Jaspers, Alyssa Turner-Strong

Oral History Posters

This is one of 31 life history interviews which are part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this project is to gather information about the history and evolution about occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. This study is intended to provide current and future generations of occupational therapists a view of the history and how occupational therapy practice has evolved from its …


Life History Of Sclinda"Cindy" Janssen, Phd, Otr/L, Courtney Haugen, Olivia Kack Jan 2018

Life History Of Sclinda"Cindy" Janssen, Phd, Otr/L, Courtney Haugen, Olivia Kack

Oral History Posters

This installation is part of a larger qualitative research study entitled Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. Thepurpose of the study is to examine influential and impactful leaders within OT practice and academia. It is anticipated that the current and future members within the OT community will be able to utilize this information to inform themselves about impactful people and occurrences within OT history.


The Neuroprotective Effects Of Targeted Temperature Management On Post-Cardiac Arrest Patients, Timothy Hovde Jan 2018

The Neuroprotective Effects Of Targeted Temperature Management On Post-Cardiac Arrest Patients, Timothy Hovde

Physician Assistant Scholarly Project Posters

Novel methods of ensuring survival following cardiac arrest and resuscitation are of supreme importance to the medical community. Targeted temperature management (TTM) has become increasingly utilized pre-hospital, in emergency departments, and within intensive care units to increase the likelihood of survival to hospital discharge. TTM has further been used to attempt to improve neurological functioning. The efficacy and mechanism behind TTM remains poorly understood. In several patient populations it also remains unproven. The purpose of this study is to assess the physiological mechanism, survival, neurological recovery and methodology of TTM use and implementation.

Literature review was utilized to assess the …


Antibiotic Therapy In Preventing Exacerbations Of Severe Chronic Obstructive Pulmonary Disease, Jamie Trautner Jan 2018

Antibiotic Therapy In Preventing Exacerbations Of Severe Chronic Obstructive Pulmonary Disease, Jamie Trautner

Physician Assistant Scholarly Project Posters

• Chronic obstructive pulmonary disease (COPD) is a progressive disease that has no cure but is treatable. The treatment goal is to have adequate symptom control, decreased exacerbations, prevent hospitalizations and maintain an independent quality of life.

• The review of literature is to determine if the benefits of long-term antimicrobial therapy outweigh the risks in the treatment of severe COPD.

• The gold standard for pharmacotherapy consists of inhaled corticosteroids and bronchodilators (long-acting beta2agonist (LABA).

• Adding azithromycin to standard therapy for patients with frequent exacerbations showed a 27% reduction in exacerbation frequency.

• With prolonged use of antimicrobials …


A Bridge Too Far? Risks And Benefits Of Perioperative Bridging Therapy, Jordan Buchholz Jan 2018

A Bridge Too Far? Risks And Benefits Of Perioperative Bridging Therapy, Jordan Buchholz

Physician Assistant Scholarly Project Posters

The long-term use of oral anticoagulants is common among certain high-risk patient populations for the prevention of thromboembolic events such as stroke, pulmonary embolism (PE), and other systemic events. According to Garwood et al. (2017) it is estimated that 15-20% of chronically anticoagulated patients will undergo a surgery or procedure that will require anticoagulation interruption annually. During this interruption period, “bridging” anticoagulant therapy is often utilized with unfractionated heparin or low-molecular weight heparin to ensure adequate anticoagulation is achieved (Ayoub et al., 2016). However, there has been an ongoing debate whether or not the benefits of perioperative anticoagulant bridging therapy …


Comparing Prevalence Of Medication-Related Osteonecrosis Of The Jaw (Mronj) Due To Denosumab And Bisphosphonates As A Side Effect Of Osteoporosis Treatment, Kendra Apland Jan 2018

Comparing Prevalence Of Medication-Related Osteonecrosis Of The Jaw (Mronj) Due To Denosumab And Bisphosphonates As A Side Effect Of Osteoporosis Treatment, Kendra Apland

Physician Assistant Scholarly Project Posters

As the baby boomer generation continues to age, the diagnosis of osteoporosis and its side effects will continue to increase. Denosumab and bisphosphonates (BPs) are some of the most common medication classes used to treat osteopenia and osteoporosis, but it is believed that both medications have the possible side effect of medication-related osteonecrosis of the jaw (MRONJ). The purpose of this paper is to uncover if MRONJ is a side effect of osteoporosis treatment and which medication carries the highest incidence rate. Through a review of several electronic databases and several peer reviewed research articles, a wide range of reported …


The Efficacy And Safety Of Statins In The Primary Prevention Of Cardiovascular Disease, Kayla M. Ashton Jan 2018

The Efficacy And Safety Of Statins In The Primary Prevention Of Cardiovascular Disease, Kayla M. Ashton

Physician Assistant Scholarly Project Posters

Atherosclerotic plaques can form in the blood vessels from particles of cholesterol. These plaques are a major cause of cardiovascular disease and have the ability to result in fatal cardiovascular events. In researching this topic, PubMed, the Cochrane Library, DynaMed, and ClinicalKey were all utilized in finding articles published from 2002 to 2018. There are several organizations with conflicting guidelines recommending the use of statin medications in the primary prevention of cardiovascular disease. The research evaluated discovers data is inconclusive on the benefit of statin medications in this primary prevention as well as the safety of long-term statin use. Some …


Exercise Therapy For Chronic Low Back Pain, Jeanmarie Dahl Jan 2018

Exercise Therapy For Chronic Low Back Pain, Jeanmarie Dahl

Physician Assistant Scholarly Project Posters

Chronic low back pain (CLBP) is currently ranked as the 13th most frequent diagnosis in family practice (DynaMedPlus, 2017). The severe nature of the pain in this condition often leads providers to prescribe narcotics. While effective in the short term, opiates have significant side effects when used chronically. Other forms of management for CLBP need to be identified and utilized. The purpose of this review was to determine the role exercise therapy plays in the management of CLBP.

Four databases were searched in order to find high quality systematic reviews, meta-analyses, and randomized controlled trials (RCT) looking at exercise therapy …


Treatment Options For Hidradenitis Suppurativa: Efficacy, Risks, Benefits, Katherine A. Hennager Jan 2018

Treatment Options For Hidradenitis Suppurativa: Efficacy, Risks, Benefits, Katherine A. Hennager

Physician Assistant Scholarly Project Posters

Hidradenitis suppurativa is a chronic, recurrent follicular occlusion disease with painful, sometimes debilitating, cutaneous draining lesions and subcutaneous abscesses (DynaMed Plus, 2016). Hidradenitis suppurativa is understood to be a multifactorial disease that is hard to treat in some patients, especially those with a severe form of the disease. For this project, the efficacy of adalimumab for hidradenitis suppurativa was assessed and whether it is more beneficial than traditional treatments used. Adalimumab is a TNF-alpha inhibitor which belongs to the biologic DMARDs drug class. Kimball et al. (2012) found that at week 16 of their trial 3.9% of the placebo patients, …


The Impact Of Circadian Misalignment On Cardiometabolic Health, Cynthia Marie Mills Jan 2018

The Impact Of Circadian Misalignment On Cardiometabolic Health, Cynthia Marie Mills

Physician Assistant Scholarly Project Posters

The circadian system is important in all living organisms because it generates a 24-hour rhythm for physiological and behavioral processes enabling anticipation and adaptation to daily changes in the environment. The prevalence of cardiometabolic diseases, which are linked to lifestyle choices, has been rising at an alarming rate. Modernization and globalization are two of many factors to blame for lifestyle changes resulting in circadian disruption. The purpose of this literature review is to explore circadian misalignment with regards to its mechanism and impact on cardiometabolic health and to determine possible interventional measures. The primary focus is on lifestyle change, particularly …


The Effectiveness Of Oral Non-Steroidal Anti-Inflammatories Versus Steroid Injections In Patients With Shoulder Pain, Darren Scott Pledger Jan 2018

The Effectiveness Of Oral Non-Steroidal Anti-Inflammatories Versus Steroid Injections In Patients With Shoulder Pain, Darren Scott Pledger

Physician Assistant Scholarly Project Posters

- The fact that shoulder pain is the most common musculoskeletal complaint in primary care shows that clinicians must have an arsenal of quality interventions to treat this problem.

- The need for quality research and evidenced based guidelines are necessary to educate clinicians on their treatment options, the efficacy of those treatments, and their safety profiles.


Associations Among Acne Vulgaris And Western Diet, Kate Meredith Suda Jan 2018

Associations Among Acne Vulgaris And Western Diet, Kate Meredith Suda

Physician Assistant Scholarly Project Posters

Acne vulgaris is one of the most common dermatologic conditions, especially among the adolescent population.

The pathogenesis of acne is largely multifactorial, with heredity and hormones strongly contributing to one’s risk of developing the chronic inflammatory skin condition.

High prevalence rates of acne in the adolescent population cannot be attributed to heredity alone, but by the influence of Western diet (WD) that overstimulates insulin-like growth factors (IGFs).

The purpose of this scholarly project is to determine if there is an association between the presence of acne vulgaris and the consumption of WD, and if a physiological link between the high …


Evolution Of Occupational Therapy Practice: The Life History Of Tammy Olson, Cota, Noelle Rivard, Kelsey Wehe Jan 2018

Evolution Of Occupational Therapy Practice: The Life History Of Tammy Olson, Cota, Noelle Rivard, Kelsey Wehe

Oral History Posters

Purpose

The life history of Tammy Olson was one of 31 life history interviews conducted for a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this study is to gather information about the history and evolution of OT practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. This study will provide current and future generations of occupational therapists and occupational therapy assistants a view of the history and how the profession has …


Evolution Of Occupational Therapy Practice: Life History Of Terry Kipp, Cota, Jacob Horn, Nora Stevenson Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Terry Kipp, Cota, Jacob Horn, Nora Stevenson

Oral History Posters

This life history is one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather information. This study is intended to provide current and …


Life History Of Zondra Thompson, Mot Otr/L, Brianna Johnson, Kylie Walthers Jan 2018

Life History Of Zondra Thompson, Mot Otr/L, Brianna Johnson, Kylie Walthers

Oral History Posters

This study offers a glimpse into the life of Zondra Thompson from the time she graduated in 1972 from the Occupational Therapy Program at the University of North Dakota to the time she retired in 2007. This life history is one of the 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories …


Evolution Of Occupational Therapy Practice: Life History Of Lanae Pickard, Otr/L, Cht, Megan Klein, Penelope Yoosook Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Lanae Pickard, Otr/L, Cht, Megan Klein, Penelope Yoosook

Oral History Posters

The life history one of 30 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming though life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. This study is intended to provide current and …


Evolution Of Occupational Therapy Practice: Life History Of Sue Morrison, Msot, Otr/L, Ashton Hudspeth, Colton Peltier Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Sue Morrison, Msot, Otr/L, Ashton Hudspeth, Colton Peltier

Oral History Posters

The life history of Sue Morrison was one of 30 life history interviews conducted as a part of a larger project of Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this project is to gather information about the history and evolution of OT practice from individuals like Sue Morrison who have been influential in developing OT in these two states This study is intended to provide current and future generations of occupational therapists a view of the history and how OT practice has evolved from its inception …


Life History Of Diane Gunderson, Otr/L, Parker Hoey, Cheyenne Hanson Jan 2018

Life History Of Diane Gunderson, Otr/L, Parker Hoey, Cheyenne Hanson

Oral History Posters

This life history is one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. This study is intended to provide current …


Evolution Of Occupational Therapy Practice: Life History Of Anne Haskins, Phd, Otr/L, Dayton Bender, Shaina Simonson Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Anne Haskins, Phd, Otr/L, Dayton Bender, Shaina Simonson

Oral History Posters

This life history is one of 31 life history interviews which contribute to a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT), in North Dakota and Wyoming.The purpose of this life history study is to gather information about the history and evolution of occupational therapy practice (OT) in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states.This study is intended to provide current and future generations of occupational therapy practitioners a view of history and OT practice has evolved from its inception …


A Piece Of The Evolution Of Occupational Therapy In North Dakota: Life History Of Rhoda Erhardt, Ms, Otr/L, Faota, Sidney Carlson, Alexis Tyce Jan 2018

A Piece Of The Evolution Of Occupational Therapy In North Dakota: Life History Of Rhoda Erhardt, Ms, Otr/L, Faota, Sidney Carlson, Alexis Tyce

Oral History Posters

This life history is one of 29 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of OT practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. By using a life history approach, this study focused on …


Evolution Of Occupational Therapy Practice: A Life History Of Jody Larson, Otr/L, Brianna Mcnelly, Nicholas Riveland Jan 2018

Evolution Of Occupational Therapy Practice: A Life History Of Jody Larson, Otr/L, Brianna Mcnelly, Nicholas Riveland

Oral History Posters

The purpose of this qualitative study was to examine the life history of occupational therapists (OT) and occupational therapy assistants (OTA) who were instrumental in developing occupational therapy practice in North Dakota or Wyoming. This is a continuation of the life history project at the University of North Dakota School of Medicine and Health Sciences (SMHS) started in 2017 as a repository of key individual’s lifetime contributions to the benefit of current and future occupational therapy practice and practitioners in the region.