Medicine and Health Sciences Commons^™

The Choice Of A Constitutive Formulation For Modeling Limb Flexion-Induced Deformations And Stresses In The Human Femoropopliteal Arteries Of Different Ages, Anastasia Desyatova, Jason Mactaggart, William Poulson, Paul Deegan, Carol Lomneth, Anjali Sandip, Alexey Kamenskiy

Mechanical Engineering Faculty Publications

Open and endovascular treatments for peripheral arterial disease are notorious for high failure rates. Severe mechanical deformations experienced by the femoropopliteal artery (FPA) during limb flexion and interactions between the artery and repair materials play important roles and may contribute to poor clinical outcomes. Computational modeling can help optimize FPA repair, but these simulations heavily depend on the choice of constitutive model describing the arterial behavior. In this study finite element model of the FPA in the standing (straight) and gardening (acutely bent) postures was built using computed tomography data, longitudinal pre-stretch and biaxially determined mechanical properties. Springs and dashpots …