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Complementary Therapies; Glucose -- therapeutic use; Joint Instability -- drug therapy; Musculoskeletal Diseases -- drug therapy; Tendinopathy -- drug therapy; Tendon Injuries -- drug therapy
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Prolotherapy: Applications, Mechanism Of Action, Controversy And Evidence, Boris M. Davydov
Prolotherapy: Applications, Mechanism Of Action, Controversy And Evidence, Boris M. Davydov
Physician Assistant Scholarly Project Posters
Merriam-Webster defines prolotherapy (PROLO) as “an alternative therapy for treating musculoskeletal pain that involves injection of irritant substance (as dextrose) into a ligament or tendon to promote the growth of new tissue”. Experimental research and multiple clinical trials have generated evidence suggesting that PROLO is effective at treating a variety of musculoskeletal conditions, including tendinopathies, joint instability and ligament laxity. PROLO may also hold a potential to delay or avoid joint replacement and rotator cuff surgeries. Further research is needed to demonstrate the therapeutic effect of PROLO unequivocally.