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Full-Text Articles in Medicine and Health Sciences

What Is A D.O.? How Do Osteopathic Physicians Approach The Problem Of Pain, Katherine E. Galluzzi Oct 2007

What Is A D.O.? How Do Osteopathic Physicians Approach The Problem Of Pain, Katherine E. Galluzzi

PCOM Scholarly Papers

No abstract provided.


Inhibition Of Apoptosis In Neuronal Cells Infected With Chlamydophila (Chlamydia) Pneumoniae, Denah M. Appelt, Maria Roupas, Deana Way, Marcus G. Bell, Elizabeth V. Albert, Christine J. Hammond, Brian J. Balin Jun 2007

Inhibition Of Apoptosis In Neuronal Cells Infected With Chlamydophila (Chlamydia) Pneumoniae, Denah M. Appelt, Maria Roupas, Deana Way, Marcus G. Bell, Elizabeth V. Albert, Christine J. Hammond, Brian J. Balin

PCOM Scholarly Papers

Background Chlamydophila (Chlamydia) pneumoniae is an intracellular bacterium that has been identified within cells in areas of neuropathology found in Alzheimer disease (AD), including endothelia, glia, and neurons. Depending on the cell type of the host, infection by C. pneumoniae has been shown to influence apoptotic pathways in both pro- and anti-apoptotic fashions. We have hypothesized that persistent chlamydial infection of neurons may be an important mediator of the characteristic neuropathology observed in AD brains. Chronic and/or persistent infection of neuronal cells with C. pneumoniae in the AD brain may affect apoptosis in cells containing chlamydial inclusions.

Results SK-N-MC neuroblastoma …


Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 2007), Philadelphia College Of Osteopathic Medicine Jun 2007

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 2007), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 2007 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

  • Opening Remarks
  • PCOM Updates and Kudos
  • Going Global: Osteopathic Medicine Enriches Worldwide Health
  • A PCOM Graduate Thinks Back to Acts of Kindness that Helped to Pull Him through the Most Difficult Time of His Life
  • Retail Health Clinics: Competitors or Collaborators?
  • Remembering Leonard Johnson, DO ’64, And William M. King, DO ’62
  • Class Notes
  • In Memoriam
  • My Turn
  • PCOM Events


Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 2007), Philadelphia College Of Osteopathic Medicine Apr 2007

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 2007), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 2007 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

  • Opening Remarks
  • PCOM Updates and Kudos
  • Development News
  • Humanism in Medicine
  • Leaders on the New Frontier of High Technology Surgery
  • Breaking the Silence Surrounding Selective Mutism
  • Remembering Ida Schmidt, DO ’35
  • Class Notes
  • In Memoriam
  • My Turn
  • PCOM Golf Classic
  • PCOM Events


Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 2007), Philadelphia College Of Osteopathic Medicine Jan 2007

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 2007), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 2007 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

  • Opening Remarks
  • Remembering Harry Ginsburg, DO ’42
  • PCOM Updates and Kudos
  • Building Partnerships: Assessing the Value of Physician-Patient Communications
  • Recognizing Leadership, Loyalty, Service: Founders’ Day 2007
  • Places, Camera, Action . . . Learning Primary Care Skills
  • Out of Africa: True Tales of a Medical Missionary
  • Class Notes
  • In Memoriam
  • My Turn
  • PCOM Events


Synapsis: Philadelphia Campus (2007), Philadelphia College Of Osteopathic Medicine Jan 2007

Synapsis: Philadelphia Campus (2007), Philadelphia College Of Osteopathic Medicine

All Yearbooks

This yearbook includes the White Coat Ceremony, Military, Clinics, DO Day on the Hill, OMM Fellows, Prom, Holidays, Follies, Parties, Trips, Awards, Class Officers.


Herpes Simplex Virus 1 And Chlamydophila (Chlamydia) Pneumoniae Promote Ab 1-42 Amyloid Processing In Murine Astrocytes Linking An Infectious Process To Alzheimer's Disease, Laura R. Triplett, Adam L. Dore, Kevin S. Kralik, Brian J. Balin, Susan T. Hingley, Denah M. Appelt Jan 2007

Herpes Simplex Virus 1 And Chlamydophila (Chlamydia) Pneumoniae Promote Ab 1-42 Amyloid Processing In Murine Astrocytes Linking An Infectious Process To Alzheimer's Disease, Laura R. Triplett, Adam L. Dore, Kevin S. Kralik, Brian J. Balin, Susan T. Hingley, Denah M. Appelt

Scholarly Posters

Background: Several studies have suggested an infectious etiology for Alzheimer's disease (AD). Previously, our laboratory identified Chlamydia pneumoniae (Cpn) from autopsied sporadic AD brains, as well as developed a BALB/c mouse model that demonstrated infection-induced amyloid plaques similar to those found in AD. Hypothesis: We propose that an additional pathogen such as herpes simplex virus type 1 (HSV1), also may be a contributing factor in toin the pathology seen in AD. HSV1, in addition to Cpn, may be triggering the abnormal cleavage of the beta amyloid precursor protein (bAPP) into Ab1-42 , thereby contributing to amyloid plaque formation. Our current …


Does Verbal Communication Impairment Affect Quality Of Life In Amyotrophic Lateral Sclerosis Patients?, Jason Michael Duff Jan 2007

Does Verbal Communication Impairment Affect Quality Of Life In Amyotrophic Lateral Sclerosis Patients?, Jason Michael Duff

PCOM Psychology Dissertations

The purpose of this study was to examine the self-perceived QOL in ALS patients. Literature will be presented on the incidence, prevalence, prognosis, diagnosis and management of ALS, QOL studies for ALS, the role of the multidisciplinary team, the impairments and dysfunction that ALS patients experience, communication issues, and the development of ALS specific instruments to measure QOL. The "bulbar dysfunction" that ALS patients experience in salivation management, speech, and swallowing were examined in detail. The objectives of this research study were to investigate the following hypotheses: 1. QOL will differ among ALS patients with varying levels of speech, swallowing, …