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Articles 61 - 90 of 105
Full-Text Articles in Medicine and Health Sciences
The Effect Of Hyperthermic Whole Body Heat Stimulus (Sauna) On Heat Shock Protein 70 And Skeletal Muscle Hypertrophy In Young Males During Weight Training, Brandon C. Jones Mr.
The Effect Of Hyperthermic Whole Body Heat Stimulus (Sauna) On Heat Shock Protein 70 And Skeletal Muscle Hypertrophy In Young Males During Weight Training, Brandon C. Jones Mr.
All NMU Master's Theses
The traditional Finnish steam sauna is theorized to aid skeletal muscle hypertrophy by stimulating Heat Shock Protein 70 (HSP70), which acts as a molecular chaperone to the folding of functional skeletal muscle. The aim of this study was to investigate if stimulating HSP70 by using a sauna (45 – 50 ͦC, 80% Humidity) three times per week, for 15 minutes, could aid skeletal muscle hypertrophy during six weeks of resistance training in a young (21.38 ± 1.9 yrs.), recreationally trained male population. Thirteen subjects were randomly distributed into 3 groups [resistance Training + sauna (RT+S, n=5), RT + Relaxation (RT+R, …
The Acute And Chronic Effects Of Highly Cushioned Shoes On Loading Characteristics In Recreational Runners, Jessica Corkin
The Acute And Chronic Effects Of Highly Cushioned Shoes On Loading Characteristics In Recreational Runners, Jessica Corkin
All NMU Master's Theses
Recently, highly cushioned shoes (HCS) entered the running market, and manufacturers suggested extra cushioning potentially reduced injury rates through superior shock absorption, implying less impact upon foot strike versus other shoes. Hence, the purpose of this study was to examine the effects of a 4-week HCS intervention on running-related impact forces in adult recreational runners. We hypothesized HCS would result in altered force attenuation compared to standard cushioned shoes (SCS) at baseline. After 4-weeks, we speculated differences would not be attenuated. Twenty-nine healthy runners (18-60 yrs of age) who had never worn HCS were randomized to either an intervention (INV) …
Characterization Of Transmembrane Protein 35 Expression: Considerations Of Sex And Ovarian Hormones, Amanda M. Vanderplow
Characterization Of Transmembrane Protein 35 Expression: Considerations Of Sex And Ovarian Hormones, Amanda M. Vanderplow
All NMU Master's Theses
The recently discovered novel neuropeptide transmembrane protein 35 (TMEM35), is believed to modulate chemical signaling within the nervous system. Notably, the TMEM35 protein is detectable in humans, non-human primates and rodents, suggesting a conserved and critical function. Despite this, the functions of TMEM35 are ill-defined in the nervous system and insufficiently studied (currently only three publications). Previous work has identified high expression of TMEM35 in both the ventromedial hypothalamus (VMH) and the limbic circuit of the mouse brain. Due to the known functions of these two regions, this pattern of expression indicates possible roles of this neuropeptide in social behavior …
The Effect Of High Altitude On Central Blood Pressure And Arterial Stiffness, Christopher Boos, Emmanuel Vincent, Adrian Mellor, David Woods, Caroline Newman, Richard Cruttenden, Matt Barlow, Mark Cooke, Kevin Deighton, Peter Scott, Sarah B. Clarke, John O'Hara
The Effect Of High Altitude On Central Blood Pressure And Arterial Stiffness, Christopher Boos, Emmanuel Vincent, Adrian Mellor, David Woods, Caroline Newman, Richard Cruttenden, Matt Barlow, Mark Cooke, Kevin Deighton, Peter Scott, Sarah B. Clarke, John O'Hara
Journal Articles
No abstract provided.
Comparison Of Clinical Versus Mechanical Measurements In Detecting Lower Limb Asymmetries Associated With A Second Acl Injury, Alicia E. Denherder
Comparison Of Clinical Versus Mechanical Measurements In Detecting Lower Limb Asymmetries Associated With A Second Acl Injury, Alicia E. Denherder
All NMU Master's Theses
Study Design: Quasi-experimental. Objectives: To compare clinical and mechanical measures in detecting lower limb asymmetries associated with second anterior cruciate ligament (ACL) injuries. Background: Knee extension moment (KExtM) asymmetry is predictive of second ACL injury. Evaluation of clinical return to sport tests to assess and classify asymmetry is needed. Methods: While performing the drop vertical jump (DVJ), thirty healthy individuals underwent 3D motion analysis. Absolute difference in KExtM between limbs at initial contact of the DVJ (KExtM symmetry) was calculated separately for each trial and averaged. Subjects performed single leg hop (SLH) and Y-Balance tests (YBT). Limb symmetry index (LSI) …
Molecular Subtyping Of Staphylococcus Aureus Isolates From The U.P. Community For The Presence Of Toxin-Encoding Genes, Carol I. Kessel
Molecular Subtyping Of Staphylococcus Aureus Isolates From The U.P. Community For The Presence Of Toxin-Encoding Genes, Carol I. Kessel
All NMU Master's Theses
Staphylococcus aureus is the most common cause of human bacterial infections; however, humans can also be asymptomatically colonized with S. aureus. Asymptomatic carriers can potentially spread S. aureus infection to others. These infections can range from mild to severe. The pathology of a S. aureus infection is often dependent on which toxins are expressed and the virulence factors with which they are associated. One goal of this study was to isolate S. aureus from healthy, consenting adult volunteers who submitted nasal swabs for culture and qRT-PCR analysis to determine which strains are present in the community. This knowledge could …
Application Of The Patient Checklist Tool In Anesthesia Handoffs, Theresa Durley
Application Of The Patient Checklist Tool In Anesthesia Handoffs, Theresa Durley
DNP Scholarly Projects
Accurate and essential communication is required during the transfer of patient care from one health care provider to another. Communication errors during the handoff process have been identified as contributing factors in sentinel events. There is a plethora of literature supporting a standardized transfer of care process as well as several accepted handoff communication tools for the various units within a healthcare institution. However, in the anesthesia domain, there is currently only one protocol specifically created for the transfer of patient care between certified registered nurse anesthetists (CRNAs). The PATIENT protocol, created by Dr. Suzanne M. Wright, CRNA, PhD (2013) …
Implementation Of The 2012 American College Of Rheumatology Guidelines For Management Of Gout In A Sample Of Midwestern Native Americans, Myrth C. Condon
Implementation Of The 2012 American College Of Rheumatology Guidelines For Management Of Gout In A Sample Of Midwestern Native Americans, Myrth C. Condon
DNP Scholarly Projects
Gout is a well understood, yet poorly treated condition that is associated with many co-morbidities including hypertension, renal and cardiac disease, metabolic syndrome, central obesity and type-2 diabetes. The American Indian population is at risk for gout due an increased incidence of type-2 diabetes, chronic kidney disease, hypertension, and alcohol abuse. The purpose of this scholarly project was to implement the 2012 American College of Rheumatology (ACR) guidelines in a sample of Tribal members within mid-western portions of the United States. This scholarly project utilized a quasi-experimental research design with pretest – posttest methods to measure uric acid levels at …
Changes In Balance And Joint Position Sense During A 12-Day High Altitude Trek: The British Services Dhaulagiri Medical Research Expedition, Sarah B. Clarke
Changes In Balance And Joint Position Sense During A 12-Day High Altitude Trek: The British Services Dhaulagiri Medical Research Expedition, Sarah B. Clarke
Datasets
Postural control and joint position sense are essential for safely undertaking leisure and professional activities, particularly at high altitude. We tested whether exposure to a 12-day trek with a gradual ascent to high altitude impairs postural control and joint position sense. This was a repeated measures observational study of 12 military service personnel (28±4 years). Postural control (sway velocity measured by a portable force platform) during standing balance, a Sharpened Romberg Test and knee joint position sense were measured, in England (113m), and at 3 research camps (3619m, 4600m and 5140m) on a 12-day high altitude trek in the Dhaulagiri …
British Services Dhaulagiri Medical Research Expedition: A Unique Military And Civilian Research Collaboration, Adrian Mellor, Josh Bakker-Dyos, Marc Howard, Christopher Boos, Mark Cooke, Emmanuel Vincent, Peter Scott, John O'Hara, Sarah B. Clarke, Matt Barlow, Jamie Matu, Kevin Deighton, Caroline Newman, Richard Cruttenden, David Holdsworth, David Woods
British Services Dhaulagiri Medical Research Expedition: A Unique Military And Civilian Research Collaboration, Adrian Mellor, Josh Bakker-Dyos, Marc Howard, Christopher Boos, Mark Cooke, Emmanuel Vincent, Peter Scott, John O'Hara, Sarah B. Clarke, Matt Barlow, Jamie Matu, Kevin Deighton, Caroline Newman, Richard Cruttenden, David Holdsworth, David Woods
Journal Articles
No abstract provided.
Changes In Appetite, Energy Intake, Body Composition And Circulating Ghrelin Constituents During An Incremental Trekking Ascent To High Altitude, Jamie Matu, John O'Hara, Neil Hill, Sarah B. Clarke, Christopher Boos, Caroline Newman, David Holdsworth, Theocharis Ispoglou, Lauren Duckworth, David Woods, Adrian Mellor, Kevin Deighton
Changes In Appetite, Energy Intake, Body Composition And Circulating Ghrelin Constituents During An Incremental Trekking Ascent To High Altitude, Jamie Matu, John O'Hara, Neil Hill, Sarah B. Clarke, Christopher Boos, Caroline Newman, David Holdsworth, Theocharis Ispoglou, Lauren Duckworth, David Woods, Adrian Mellor, Kevin Deighton
Journal Articles
No abstract provided.
Evaluation Of A Multiplex Real-Time Pcr Assay To Simultaneously Detect Streptococcus Pneumoniae And Staphylococcus Aureus In Nasal Samples, Polly Hockberger
Evaluation Of A Multiplex Real-Time Pcr Assay To Simultaneously Detect Streptococcus Pneumoniae And Staphylococcus Aureus In Nasal Samples, Polly Hockberger
All NMU Master's Theses
Invasive disease caused by Streptococcus pneumoniae and Staphylococcus aureus is associated with nasal carriage of these bacteria. Use of a pneumococcal conjugate vaccine (PCV) in children altered nasal carriage rates and reduced infections due to S. pneumonia. Similar studies demonstrate that there is an inverse correlation between S. pneumoniae and S. aureus nasal carriage in children, but this inverse correlation has not been extensively investigated adults. The PCV is now approved for use in adults, a group more likely to be colonized with S. aureus. To investigate the impact of PCV vaccination on S. aureus carriage in adults, the …
A Comparison Of Stride Length And Lower Extremity Kinematics During Barefoot And Shod Running In Well Trained Distance Runners, Peter Francis, James Ledingham, Sarah B. Clarke Phd, Dj Collins, Philip Jakeman
A Comparison Of Stride Length And Lower Extremity Kinematics During Barefoot And Shod Running In Well Trained Distance Runners, Peter Francis, James Ledingham, Sarah B. Clarke Phd, Dj Collins, Philip Jakeman
Journal Articles
Stride length, hip, knee and ankle angles were compared during barefoot and shod running on a treadmill at two speeds. Nine well-trained (1500m time: 3min:59.80s ± 14.7 s) male (22 ±3 years; 73 ±9 kg; 1.79 ±0.4 m) middle distance (800 m – 5,000 m) runners performed 2 minutes of running at 3.05 m·s-1 and 4.72 m·s-1 on an treadmill. This approach allowed continuous measurement of lower extremity kinematic data and calculation of stride length. Statistical analysis using a 2X2 factorial ANOVA revealed speed to have a main effect on stride length and hip angle and footwear to …
Upper Body Characteristics Related To Double Pole Performance In Female Cross Country Skiers, Karmen M. Whitham
Upper Body Characteristics Related To Double Pole Performance In Female Cross Country Skiers, Karmen M. Whitham
All NMU Master's Theses
The purpose of the current study was to correlate upper body (UB) lean mass (UBLM), UB maximal strength (UBMS), and average power production during a 3-min ski ergometer (SERG) test to predict the dependent variable, a one-kilometer uphill double pole time trial (DPTT) on snow. We hypothesized UBLM would be most important to performance. All tests were conducted within four weeks of completing the championship phase of a Division I cross country (XC) ski season. Skiers (n=10; all females) performed the mass-start DPTT on snow (i.e., criterion measure), SERG, and UBMS separated by at least a few days recovery. Lastly, …
Reactive Strength Index-Modified In Different Plyometric Tasks, Josh Walker, Sarah B. Clarke, Emma Waller, Aaron Robey-Broome, Randall L. Jensen
Reactive Strength Index-Modified In Different Plyometric Tasks, Josh Walker, Sarah B. Clarke, Emma Waller, Aaron Robey-Broome, Randall L. Jensen
Conference Presentations
The Reactive Strength Index-Modified (RSlmod) is a reliable method of measuring the explosiveness of an athlete during a range of plyometric exercises. The purpose of the current study was to measure the between-limb differences in RSlmod across three different plyometric tasks. Eleven recreationally active participants performed countermovement jumps, stop jumps and single-leg jumps. The study found no significant differences in RSlmod between dominant and non-dominant limbs across all three tasks (p>0.05), but did find RSI,d to be higher in the stop jump than a countermovement jump and single leg stop jump for both dominant and non-dominant limbs. These findings …
12-Day Adventure Run-Hike Training At Altitude Improves Sea Level 5km Performance, Andrew M. Jones
12-Day Adventure Run-Hike Training At Altitude Improves Sea Level 5km Performance, Andrew M. Jones
All NMU Master's Theses
Elite and recreational endurance athletes routinely seek strategies to enhance sea level (SL) performance. Altitude (ALT) training continues to be an appealing approach. The primary purpose of this study was to measure the effect of a 12-day adventure running camp at ALT on 5 km time trial (TT) performance at SL. Secondarily, we explored changes in select metabolic and blood variables. We hypothesized an improvement in TT at SL. A group of five well-trained individuals (2 females) volunteered. TT, maximal oxygen uptake (VO2max), running economy (RE), and a complete blood count (CBC) were measured at SL before and …
7-Weeks Of Yoga Training And Its Effects On Flexibility, Rate Of Force Development, And Jump Height In Olympic Weightlifters, Andrew Ernst
7-Weeks Of Yoga Training And Its Effects On Flexibility, Rate Of Force Development, And Jump Height In Olympic Weightlifters, Andrew Ernst
All NMU Master's Theses
The purpose of the current study was to determine what effects 7-weeks of yoga training had on Olympic weightlifters flexibility, rate of force development, and jump height. Pre- and post-testing was performed consisting of flexibility and jump performance measurements. The participants performed a sit and reach test followed by a loaded overhead squat test with barbell. The overhead squat test was performed with reflective markers and recorded video to assess joint angles. A countermovement jump and snatch, at 80% of their one repetition maximum, was performed next to measure rate of force development and jump height. The participants then were …
A Novel And Rapid Staphylococcus Aureus Bacterial Identification Method Utilizing Immunomagnetic Beads And Single Cell Laser-Light Scattering, Kaylagh Hollen
A Novel And Rapid Staphylococcus Aureus Bacterial Identification Method Utilizing Immunomagnetic Beads And Single Cell Laser-Light Scattering, Kaylagh Hollen
All NMU Master's Theses
Staphylococcus aureus is the most commonly isolated human associated bacterial pathogen. It plays an important role in skin and soft-tissue infections, pneumonia, endocarditis, osteomyelitis, foreign-body infections, and sepsis. S. aureus diagnosis and treatment requires a minimum of 24-48. With this in mind, previous studies suggest that faster pathogen identification has been linked to improved patient outcomes. Improved patient outcomes including a reduction in hospitalization time, decreased risk of nosocomial infections, and decreased in medical costs. The impact of faster identification on patient outcome has led us to develop an alternative method of S. aureus identification via ImmunoMagnetic Separation (IMS) and …
Examination Of Cd133 And Cd147 As Cancer Stem Cell Markers, Christopher Mcmahon
Examination Of Cd133 And Cd147 As Cancer Stem Cell Markers, Christopher Mcmahon
All NMU Master's Theses
To date, as many as 14,000 patients in the United States per year are diagnosed with glioblastoma, the most common and most malignant primary brain tumor. Glioblastomas are characterized by their ability to evade treatment on many fronts, thus a novel approach to curative therapies is imperative. A population of cells with stem cell-like properties are found within glioblastoma tumors and drive their initiation and progression. Identification of extracellular markers on these tumor stem cells is thus paramount. The cell surface glycoproteins CD133 and CD147 were examined as potential markers of cancer stem cells found in glioblastoma. Here we found …
Analysis Of Tumor Specific Protein Expression In Glioblastoma Multiforme (Gbms) Tumors Through Immunohistochemistry, Amanda M. Wigand
Analysis Of Tumor Specific Protein Expression In Glioblastoma Multiforme (Gbms) Tumors Through Immunohistochemistry, Amanda M. Wigand
All NMU Master's Theses
GBM tumors are the most aggressive and, unfortunately, the most fatal form of brain cancer. GBM tumors with isocitrate dehydrogenase-1 (IDH1) mutation being expressed, lead to higher survival rates in patients that also have full resection of the tumor and chemotherapy. Without this mutation, it is thought that tumors have a higher expression of the protein Basigin and O6-methylguanine-DNA-methyltrasnferase (MGMT) present, causing it to be more aggressive and less responsive to standard care. The objective of this study was to understand the correlation between IDH1 mutation presence and the expression of Basigin and MGMT. The expression of these proteins was …
Reactive Strength Index-Modified In Different Plyometric Tasks, Josh Walker, Sarah B. Clarke, Emma Waller, Aaron Robey-Broome, Randall L. Jensen
Reactive Strength Index-Modified In Different Plyometric Tasks, Josh Walker, Sarah B. Clarke, Emma Waller, Aaron Robey-Broome, Randall L. Jensen
Conference Presentations
No abstract provided.
Intracranial Infusions Of Neurotensin Agonists Produce An Anxiolytic Profile In A Rat Ultrasonic Vocalization Model, Floyd F. Steele Iii
Intracranial Infusions Of Neurotensin Agonists Produce An Anxiolytic Profile In A Rat Ultrasonic Vocalization Model, Floyd F. Steele Iii
All NMU Master's Theses
Neurotensin (NT) is a peptide neurotransmitter that interacts with brain monoamine neurotransmitter systems. It has been demonstrated that neurotensin type 1 and type 2 receptor agonists influence animal models of psychological disorders and pain regulation, respectively. It has already been shown that the systemic administration of the selective neurotensin type 1 receptor agonist PD149163 can attenuate the number of fear-induced 22-kHz ultrasonic vocalizations (USVs) produced by male Wistar rats. A reduction in the number of 22-kHz USV calls is indicative of an anxiolytic effect. The current study used a USV model to evaluate the effects of PD149163 (0.1, 1.0, and …
Exercise Intensity And Performance Aspects Of Snow Biking Through The Use Of A Fat Bike, Kevin C. Phillips
Exercise Intensity And Performance Aspects Of Snow Biking Through The Use Of A Fat Bike, Kevin C. Phillips
All NMU Master's Theses
The aim of this study was to quantify, describe, and compare the exercise intensity and performance aspects of riding a fat bike, in a time trial (TT) format, on a natural earthen trail (ET) vs. on a groomed snow trail (ST). Eleven subjects, nine males and two females, participated in this two part study. Heart rate (HR) was used to quantify exercise intensity, examining average heart rate (HRavg), and peak heart rate (HRpeak). In addition, a global positioning system (GPS) watch was used to assess time to complete the trail, average speed (speedavg), and …
The Acute Effects Of The Prevent Injury Enhance Performance Programme (Pep) On Acl Injury Risk Factors, Chris Mccann, Sarah B. Clarke
The Acute Effects Of The Prevent Injury Enhance Performance Programme (Pep) On Acl Injury Risk Factors, Chris Mccann, Sarah B. Clarke
Conference Presentations
No abstract provided.
A Cohort Study Investigating Autoantibody Levels During And After Infection With Influenza A Virus, Michelle Collins
A Cohort Study Investigating Autoantibody Levels During And After Infection With Influenza A Virus, Michelle Collins
All NMU Master's Theses
Antinuclear autoantibodies (ANAs) are present in all individuals. In those with autoimmune diseases they are routinely present in elevated levels. Although the nature and development of autoimmune diseases are not fully understood there are many hypotheses as to possible causes of an autoimmune disorder. One possible cause is viral infections. The scope of this thesis study was to examine if autoantibodies levels in individuals without autoimmune disorders increase during or after infection with influenza A virus. Blood was collected from volunteers (n=11) at time intervals of 0, 7, 42 and 63 days, respectively. Antibody levels were measured using ELISA assays …
The Effects Of High Intensity Intermittent Exercise In Normobaric Hypoxia On Aerobic Capacity And Body Composition In Overweight And Obese Sedentary Adults, Max W. Adolphs
All NMU Master's Theses
The purpose of this study was to examine if high intensity intermittent exercise (HIIE) combined with normobaric hypoxia had a multiplicative effect on body composition, maximal oxygen uptake (VO2max), and resting energy expenditure (REE) in overweight and obese sedentary adults. Twelve participates were recruited for the study. Participants were randomly assigned to either a hypoxic training (HT) group equivalent to 3,048 m (FIO2 = 14.5%) or a normoxic training (NT) group equivalent to 0 m (FIO2 = 20.9%) three times a week for six weeks in a normobaric hypoxic chamber. HIIE consisted …
Digigogy: Toward A Pedagogy Of Connections, Chris Kirk, Patricia Hogan, Breanne R. Carlson
Digigogy: Toward A Pedagogy Of Connections, Chris Kirk, Patricia Hogan, Breanne R. Carlson
Conference Presentations
No abstract provided.
Lower Limb Coordination During A Land-Cut Task Following Anterior Cruciate Ligament Reconstruction And Rehabilitation, Sarah B. Clarke, Ian Kenny, Andrew Harrison
Lower Limb Coordination During A Land-Cut Task Following Anterior Cruciate Ligament Reconstruction And Rehabilitation, Sarah B. Clarke, Ian Kenny, Andrew Harrison
Conference Presentations
No abstract provided.
Examining Success In Health Information Technology Implementation Research, Madison Ngafeeson
Examining Success In Health Information Technology Implementation Research, Madison Ngafeeson
Conference Presentations
The implementation of health information systems (IS) is rapidly increasing. In the United States, $70 billion will be invested by the government to facilitate the adoption of the electronic health record over a ten-year period. However, IS acceptance is not success. We use content analysis to investigate the success component.
An Exploratory Study Of User Resistance In Healthcare It, Madison Ngafeeson, Vishal Midha
An Exploratory Study Of User Resistance In Healthcare It, Madison Ngafeeson, Vishal Midha
Journal Articles
The US healthcare system is clearly experiencing a major transition. By 2015, the healthcare sector is expected to have migrated from a paper record system to a completely electronic health record (EHR) system. The adoption and use of these systems are expected to increase legibility, reduce costs, limit medical errors and improve the overall quality of healthcare. Hence, the US government is investing $70 billion over a 10-year period to facilitate the transition to an electronic system. However, early reports show that physicians and nurses among other health professionals continue to resist the full use of the system. This paper …