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Australian Catholic University

Pregnancy

Chemicals and Drugs

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Full-Text Articles in Medicine and Health Sciences

Validation Of Trichloroacetic Acid Exposure Via Drinking Water During Pregnancy Using A Urinary Tcaa Biomarker, Rachel B. Smith, Mark J. Nieuwenhuijsen, John Wright, Pauline Raynor, John Cocker, Kate Jones, Maria Kostopoulou-Karadanelli, Mireille B. Toledano Jan 2013

Validation Of Trichloroacetic Acid Exposure Via Drinking Water During Pregnancy Using A Urinary Tcaa Biomarker, Rachel B. Smith, Mark J. Nieuwenhuijsen, John Wright, Pauline Raynor, John Cocker, Kate Jones, Maria Kostopoulou-Karadanelli, Mireille B. Toledano

Faculty of Health Sciences Publications

Disinfection by-product (DBP) exposure during pregnancy may be related to reduced fetal growth, but the evidence is inconclusive and improved DBP exposure assessment is required. The authors conducted a nested exposure study on a subset (n=39) of pregnant women in the Born in Bradford cohort to assess validity of TCAA exposure assessment based on tap water sampling and self-reported water-use; water-use questionnaire validity; and use of a one-time urinary TCAA biomarker. TCAA levels in urine and home tap water supply were quantified, and water use was measured via a questionnaire and 7-day diary, at 28 weeks gestation. Diary and ...