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Australian Catholic University

2014

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Articles 1 - 30 of 200

Full-Text Articles in Medicine and Health Sciences

The Journey From New Graduate To Proficient Nurse In The Intensive Care Unit: A Descriptive Phenomenological Study, Farida Saghafi Aug 2014

The Journey From New Graduate To Proficient Nurse In The Intensive Care Unit: A Descriptive Phenomenological Study, Farida Saghafi

Theses

The rationale for study was the increased need for critical care services, the shortage of experienced critical care nurses, and the unidentified factors affecting nurse retention after completion of New Graduate/Transition to Practice Program in the critical care area. New graduate nurses were provided with an opportunity to share their experiences as they developed and achieved levels of proficiency over time in Intensive Care Unit (ICU). Although most new graduate nurses in New South Wales (NSW) progress through a Transition to Practice Program, limited research has been conducted concerning their lived experience of what they deem to be important ...


Evaluation Of A Behaviour Change Intervention Targeting Evidence-Based Management Of Fever, Hyperglycaemia And Swallowing Dysfunction Following Acute Stroke, Peta Drury Aug 2014

Evaluation Of A Behaviour Change Intervention Targeting Evidence-Based Management Of Fever, Hyperglycaemia And Swallowing Dysfunction Following Acute Stroke, Peta Drury

Theses

Stroke is Australia’s second highest cause of death and a leading cause of adult disability (1- 3). Several factors influence morbidity and mortality after ischaemic stroke, including fever, hyperglycaemia and swallowing dysfunction (4-8). Early detection and treatment of these three physiological variables should be a priority (4-8). National and international guidelines (9-13) provide recommendations for the management of fever, hyperglycaemia and swallowing dysfunction following acute stroke; however, only a small proportion of Australians receive evidence-based care (14-18). Prior studies have identified that the distribution alone of guidelines will not change clinician behaviour (19); thus, further research is required to ...


Facilitating Clinical Transition In The Midst Of Cultural Diversity: Challenges And Strategies, Jennie Robinson Jun 2014

Facilitating Clinical Transition In The Midst Of Cultural Diversity: Challenges And Strategies, Jennie Robinson

Theses

The clinical facilitator (CF) role has evolved to enable the clinical transition of the growing numbers of culturally and linguistically diverse overseas qualified (CALD OSQ) nurses who have brought nursing experience and knowledge to Australia. The presence of CALD OSQ nurses in Australia reflected globalisation patterns of nursing which contributed to the imbalance of the distribution of global health service delivery. The continued reliance on CALD OSQ nurses has added to the overwhelming health workforce shortages in developing nations. However the World Health Organisation (2010) proposed the origins of the health workforce crisis stemmed from the gulf between health professional ...


Investigation Of Registered Nurses' Clinical Decision-Making Processes In Aged Care, Marina Lucia Lomonaco Apr 2014

Investigation Of Registered Nurses' Clinical Decision-Making Processes In Aged Care, Marina Lucia Lomonaco

Theses

An ageing global population places increasing humanitarian and financial loads on government, health and welfare agencies; necessitating change and innovation to meet and manage clinical and physically complex needs and demands. Australian residential aged care has been influenced by these international and jurisdictional socio-political forces. This thesis aims to inform healthcare professionals and others about Australian aged care registered nurse (RN) decision-making processes, as well as convey understanding of the responsibilities and contextual influences upon RNs working in this sector and scope of practice according to their professional responsibilities...


Impact Of Warm-Up Intensity On Simulated Team-Sport Running Performance, Grant Rowe Mar 2014

Impact Of Warm-Up Intensity On Simulated Team-Sport Running Performance, Grant Rowe

Theses

Ideally, warm-ups optimise performance; however, most warm-ups are prescribed based on trial and error rather than applying an evidence-based approach (Fradkin, Zazryn, & Smoliga, 2010). The most appropriate warm-up strategy for optimal team-sport performance remains elusive. While the impact of warm-up intensity on repeated-sprint performance has been examined (Yaicharoen, Wallman, Bishop, & Morton, 2012), sprinting only constitutes a fraction of the total activity that occurs during a match. Optimising submaximal efforts (e.g. jogging, running) between sprints may impact performance by ensuring correct positioning of players and recovery between sprint efforts. There is little research investigating the impact of warm-up on team-sport ...


Adverse Events Following Intensive Care Discharge: The Contribution Of System, Clinician And Patient Factors, Malcolm Elliott Mar 2014

Adverse Events Following Intensive Care Discharge: The Contribution Of System, Clinician And Patient Factors, Malcolm Elliott

Theses

An adverse medical event is any unintended injury or complication that arises from health care management rather than the patient’s underlying disease, and results in disability, death or a prolonged hospital stay. Unfortunately, these events occur frequently across the care continuum including in patients recently discharged from Intensive Care Units (ICU). Currently there is limited understanding of adverse events in hospitalised post-ICU patients. Given the significant costs, consequences and preventability of these events, greater understanding of post-ICU adverse events is needed.


"I Try And Smile, I Try And Be Cheery, I Try Not To Be Pushy. I Try To Say 'I'M Here For Help' But I Leave Feeling... Worried": A Qualitative Study Of Perceptions Of Interactions With Health Professionals By Community-Based Older Adults With Chronic Pain, Amanda Clarke, Denis Martin, Derek Jones, Patricia Schofield, Geraldine Anthony, Paul Mcnamee, Denise Gray, Blair H. Smith Jan 2014

"I Try And Smile, I Try And Be Cheery, I Try Not To Be Pushy. I Try To Say 'I'M Here For Help' But I Leave Feeling... Worried": A Qualitative Study Of Perceptions Of Interactions With Health Professionals By Community-Based Older Adults With Chronic Pain, Amanda Clarke, Denis Martin, Derek Jones, Patricia Schofield, Geraldine Anthony, Paul Mcnamee, Denise Gray, Blair H. Smith

Faculty of Health Sciences Publications

Background: Over 50% of community-dwelling older adults experience chronic pain, which threatens their quality of life. Of importance to their pain management is older people's interaction with health professionals that, if unsatisfactory, may impair the outcome. Aims: To add to the limited research specific to older people living with chronic pain in the community, we explored how they perceive their experiences of interacting with health professionals, seeking factors that might optimise these interactions. Methods: Purposive sampling was used to recruit men and women > 65 years with self-reported musculoskeletal chronic pain. Qualitative individual interviews and one group interview were undertaken ...


The Electronic Self Report Assessment And Intervention For Cancer: Promoting Patient Verbal Reporting Of Symptom And Quality Of Life Issues In A Randomized Controlled Trial, Donna L. Berry, Fangxin Hong, Barbara Halpenny, Anne Partridge, Erica Fox, Jesse R. Fann, Seth Wolpin, William B. Lober, Nigel Bush, Upendra Parvathaneni, Dagmar Amtmann, Rosemary Ford Jan 2014

The Electronic Self Report Assessment And Intervention For Cancer: Promoting Patient Verbal Reporting Of Symptom And Quality Of Life Issues In A Randomized Controlled Trial, Donna L. Berry, Fangxin Hong, Barbara Halpenny, Anne Partridge, Erica Fox, Jesse R. Fann, Seth Wolpin, William B. Lober, Nigel Bush, Upendra Parvathaneni, Dagmar Amtmann, Rosemary Ford

Faculty of Health Sciences Publications

The electronic self report assessment - cancer (ESRA-C), has been shown to reduce symptom distress during cancer therapy The purpose of this analysis was to evaluate aspects of how the ESRA-C intervention may have resulted in lower symptom distress (SD).


Traffic-Related Air Pollution And Congenital Anomalies In Barcelona, Anna Schembari, Mark J. Nieuwenhuijsen, Joaquin Salvador, Audrey De Nazelle, Marta Cirach, Payam Dadvand, Rob Beelen, Gerard Hoek, Xavier Basagaña, Martine Vrijheid Jan 2014

Traffic-Related Air Pollution And Congenital Anomalies In Barcelona, Anna Schembari, Mark J. Nieuwenhuijsen, Joaquin Salvador, Audrey De Nazelle, Marta Cirach, Payam Dadvand, Rob Beelen, Gerard Hoek, Xavier Basagaña, Martine Vrijheid

Faculty of Health Sciences Publications

Background: A recent meta-analysis suggested evidence for an effect of exposure to ambient air pollutants on risk of certain congenital heart defects. However, few studies have investigated the effects of traffic-related air pollutants with sufficient spatial accuracy. Objectives: We estimated associations between congenital anomalies and exposure to traffic-related air pollution in Barcelona, Spain. Method: Cases with nonchromosomal anomalies (n = 2,247) and controls (n = 2,991) were selected from the Barcelona congenital anomaly register during 1994–2006. Land use regression models from the European Study of Cohorts for Air Pollution Effects (ESCAPE), were applied to residential addresses at birth to ...


Accessibility And Use Of Urban Green Spaces, And Cardiovascular Health: Findings From A Kaunas Cohort Study, Abdonas Tamosiunas, Regina Grazuleviciene, Dalia Luksiene, Audrius Dedele, Regina Reklaitiene, Migle Baceviciene, Jone Vencloviene, Gailute Bernotiene, Ricardas Radisauskas, Vilija Malinauskiene, Egle Milinaviciene, Martin Bobak, Anne Peasey, Mark J. Nieuwenhuijsen Jan 2014

Accessibility And Use Of Urban Green Spaces, And Cardiovascular Health: Findings From A Kaunas Cohort Study, Abdonas Tamosiunas, Regina Grazuleviciene, Dalia Luksiene, Audrius Dedele, Regina Reklaitiene, Migle Baceviciene, Jone Vencloviene, Gailute Bernotiene, Ricardas Radisauskas, Vilija Malinauskiene, Egle Milinaviciene, Martin Bobak, Anne Peasey, Mark J. Nieuwenhuijsen

Faculty of Health Sciences Publications

Background: The aims of this study were to explore associations of the distance and use of urban green spaces with the prevalence of cardiovascular diseases (CVD) and its risk factors, and to evaluate the impact of the accessibility and use of green spaces on the incidence of CVD among the population of Kaunas city (Lithuania). Methods: We present the results from a Kaunas cohort study on the access to and use of green spaces, the association with cardiovascular risk factors and other health-related variables, and the risk of cardiovascular mortality and morbidity. A random sample of 5,112 individuals aged ...


Four Weeks Of Iv Iron Supplementation Reduces Perceived Fatigue And Mood Disturbance In Distance Runners, Amy L. Woods, Laura A. Garvican-Lewis, Philo U. Saunders, Greg Lovell, David Hughes, Ruth Fazakerley, Bev Anderson, Christopher J. Gore, Kevin G. Thompson Jan 2014

Four Weeks Of Iv Iron Supplementation Reduces Perceived Fatigue And Mood Disturbance In Distance Runners, Amy L. Woods, Laura A. Garvican-Lewis, Philo U. Saunders, Greg Lovell, David Hughes, Ruth Fazakerley, Bev Anderson, Christopher J. Gore, Kevin G. Thompson

Faculty of Health Sciences Publications

Purpose: To determine the effect of intravenous iron supplementation on performance, fatigue and overall mood in runners without clinical iron deficiency. Methods: Fourteen distance runners with serum ferritin 30–100 µg·L−1 were randomly assigned to receive three blinded injections of intravenous ferric-carboxymaltose (2 ml, 100 mg, IRON) or normal saline (PLACEBO) over four weeks (weeks 0, 2, 4). Athletes performed a 3,000 m time trial and 10×400 m monitored training session on consecutive days at week 0 and again following each injection. Hemoglobin mass (Hbmass) was assessed via carbon monoxide rebreathing at weeks 0 and 6 ...


Positive Health Effects Of The Natural Outdoor Environment In Typical Populations In Different Regions In Europe (Phenotype): A Study Programme Protocol, Mark J. Nieuwenhuijsen, Hanneke Kruize, Christopher Gidlow, Sandra Andrusaityte, Josep M. Antó, Xavier Basagaña, Marta Cirach, Payam Dadvand, Asta Danileviciute, David Donaire-Gonzalez, Judith Garcia, Michael Jerrett, Marc V. Jones, Jordi Julvez, Elise Van Kempen, Irene Van Kamp, Jolanda Maas, Edmund Seto, Graham Smith, Margarita Triguero, Wanda Wendel-Vos, John Wright, Joris Zufferey, Peter Van Den Hazel, Roderick Lawrence, Regina Gražulevičienė Jan 2014

Positive Health Effects Of The Natural Outdoor Environment In Typical Populations In Different Regions In Europe (Phenotype): A Study Programme Protocol, Mark J. Nieuwenhuijsen, Hanneke Kruize, Christopher Gidlow, Sandra Andrusaityte, Josep M. Antó, Xavier Basagaña, Marta Cirach, Payam Dadvand, Asta Danileviciute, David Donaire-Gonzalez, Judith Garcia, Michael Jerrett, Marc V. Jones, Jordi Julvez, Elise Van Kempen, Irene Van Kamp, Jolanda Maas, Edmund Seto, Graham Smith, Margarita Triguero, Wanda Wendel-Vos, John Wright, Joris Zufferey, Peter Van Den Hazel, Roderick Lawrence, Regina Gražulevičienė

Faculty of Health Sciences Publications

Introduction: Growing evidence suggests that close contact with nature brings benefits to human health and well-being, but the proposed mechanisms are still not well understood and the associations with health remain uncertain. The Positive Health Effects of the Natural Outdoor environment in Typical Populations in different regions in Europe (PHENOTYPE) project investigates the interconnections between natural outdoor environments and better human health and well-being. Aims and methods: The PHENOTYPE project explores the proposed underlying mechanisms at work (stress reduction/restorative function, physical activity, social interaction, exposure to environmental hazards) and examines the associations with health outcomes for different population groups ...


Investing In Longitudinal Studies Of Primary Healthcare: What Can We Learn About Service Performance, Sustainability And Quality?, Bernadette M. Ward, P. F. Buykx, Rachel Tham, Leigh Kinsman, John S. Humphreys Jan 2014

Investing In Longitudinal Studies Of Primary Healthcare: What Can We Learn About Service Performance, Sustainability And Quality?, Bernadette M. Ward, P. F. Buykx, Rachel Tham, Leigh Kinsman, John S. Humphreys

Faculty of Health Sciences Publications

No abstract provided.


High-Sensitivity Troponin T And Risk Stratification In Patients With Atrial Fibrillation During Treatment With Apixaban Or Warfarin, Ziyad Hijazi, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, John H. Alexander, Dan Atar, Bernard J. Gersh, Michael Hanna, Veli-Pekka Harjola, John D. Horowitz, Steen Husted, Elaine M. Hylek, Renato D. Lopes, John J.V. Mcmurray, Christopher B. Granger Jan 2014

High-Sensitivity Troponin T And Risk Stratification In Patients With Atrial Fibrillation During Treatment With Apixaban Or Warfarin, Ziyad Hijazi, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, John H. Alexander, Dan Atar, Bernard J. Gersh, Michael Hanna, Veli-Pekka Harjola, John D. Horowitz, Steen Husted, Elaine M. Hylek, Renato D. Lopes, John J.V. Mcmurray, Christopher B. Granger

Faculty of Health Sciences Publications

Objectives The aim of this study was to evaluate the prognostic value of high-sensitivity troponin T (hs-TnT) in addition to clinical risk factors and the CHA2DS2VASc (congestive heart failure, hypertension, 75 years of age and older, diabetes mellitus, previous stroke or transient ischemic attack, vascular disease, 65 to 74 years of age, female) risk score in patients with atrial fibrillation (AF). Background The level of troponin is a powerful predictor of cardiovascular events and mortality. Methods A total of 14,897 patients with AF were randomized to treatment with apixaban or warfarin in the ARISTOTLE (Apixaban for the Prevention of ...


Value Of Biomarkers In Osteoarthritis: Current Status And Perspectives, M. Lotz, Johanne Martel-Pelletier, Claus Christiansen, Maria Luisa Brandi, O. Bruyère, Roland D. Chapurlat, J. Collette, Cyrus Cooper, G. Giacovelli, John A. Kanis, M. A. Karsdal, V. Kraus, Willem F. Lems, I. Meulenbelt, Jean Pierre Pelletier, J. P. Raynauld, S. Reiter-Niesert, R. Rizzoli, L. J. Sandell, W. E. Van Spil, Jean Yves Reginster Jan 2014

Value Of Biomarkers In Osteoarthritis: Current Status And Perspectives, M. Lotz, Johanne Martel-Pelletier, Claus Christiansen, Maria Luisa Brandi, O. Bruyère, Roland D. Chapurlat, J. Collette, Cyrus Cooper, G. Giacovelli, John A. Kanis, M. A. Karsdal, V. Kraus, Willem F. Lems, I. Meulenbelt, Jean Pierre Pelletier, J. P. Raynauld, S. Reiter-Niesert, R. Rizzoli, L. J. Sandell, W. E. Van Spil, Jean Yves Reginster

Faculty of Health Sciences Publications

Osteoarthritis affects the whole joint structure with progressive changes in cartilage, menisci, ligaments and subchondral bone, and synovial inflammation. Biomarkers are being developed to quantify joint remodelling and disease progression. This article was prepared following a working meeting of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis convened to discuss the value of biochemical markers of matrix metabolism in drug development in osteoarthritis. The best candidates are generally molecules or molecular fragments present in cartilage, bone or synovium and may be specific to one type of joint tissue or common to them all. Many currently investigated ...


Reading And Language Intervention For Children At Risk Of Dyslexia: A Randomised Controlled Trial, Fiona J. Duff, Charles Hulme, Katy Grainger, Samantha J. Hardwick, Jeremy N.V. Miles, Margaret J. Snowling Jan 2014

Reading And Language Intervention For Children At Risk Of Dyslexia: A Randomised Controlled Trial, Fiona J. Duff, Charles Hulme, Katy Grainger, Samantha J. Hardwick, Jeremy N.V. Miles, Margaret J. Snowling

Faculty of Health Sciences Publications

Background: Intervention studies for children at risk of dyslexia have typically been delivered preschool, and show short-term effects on letter knowledge and phoneme awareness, with little transfer to literacy. Methods: This randomised controlled trial evaluated the effectiveness of a reading and language intervention for 6-year-old children identified by research criteria as being at risk of dyslexia (n = 56), and their school-identified peers (n = 89). An Experimental group received two 9-week blocks of daily intervention delivered by trained teaching assistants; the Control group received 9 weeks of typical classroom instruction, followed by 9 weeks of intervention. Results: Following mixed effects regression ...


The Power Of Anticipated Feedback: Effects On Students' Achievement Goals And Achievement Emotions, Reinhard Pekrun, Aisling Cusack, Kou Murayama, Andrew J. Elliot, Kevin Thomas Jan 2014

The Power Of Anticipated Feedback: Effects On Students' Achievement Goals And Achievement Emotions, Reinhard Pekrun, Aisling Cusack, Kou Murayama, Andrew J. Elliot, Kevin Thomas

Faculty of Health Sciences Publications

In an experimental study (N = 153 high school students), we tested a theoretical model positing that anticipated achievement feedback influences achievement goals and achievement emotions, and that achievement goals mediate the link between anticipated feedback and emotions. Participants were informed that they would receive self-referential feedback, normative feedback, or no feedback for their performance on a test. Subsequently, achievement goals and discrete achievement emotions regarding the test were assessed. Self-referential feedback had a positive influence on mastery goal adoption, whereas normative feedback had a positive influence on performance-approach and performance-avoidance goal adoption. Furthermore, feedback condition and achievement goals predicted test-related ...


A Formative Evaluation Of The Implementation Of An Upper Limb Stroke Rehabilitation Intervention In Clinical Practice: A Qualitative Interview Study, Louise Connell, Naoimh E. Mcmahon, Jocelyn E. Harris, Caroline Watkins, Janice J. Eng Jan 2014

A Formative Evaluation Of The Implementation Of An Upper Limb Stroke Rehabilitation Intervention In Clinical Practice: A Qualitative Interview Study, Louise Connell, Naoimh E. Mcmahon, Jocelyn E. Harris, Caroline Watkins, Janice J. Eng

Faculty of Health Sciences Publications

Background: The Graded Repetitive Arm Supplementary Program (GRASP) is a hand and arm exercise programme designed to increase the intensity of exercise achieved in inpatient stroke rehabilitation. GRASP was shown to be effective in a randomised controlled trial in 2009 and has since experienced unusually rapid uptake into clinical practice. The aim of this study was to conduct a formative evaluation of the implementation of GRASP to inform the development and implementation of a similar intervention in the United Kingdom. Methods: Semi-structured interviews were conducted with therapists who were involved in implementing GRASP at their work site, or who had ...


Novel Implications Of Lingo-1 And Its Signaling Partners In Schizophrenia, F. Fernandez-Enright, J. L. Andrews, K. A. Newell, C. Pantelis, X.-F. Huang Jan 2014

Novel Implications Of Lingo-1 And Its Signaling Partners In Schizophrenia, F. Fernandez-Enright, J. L. Andrews, K. A. Newell, C. Pantelis, X.-F. Huang

Faculty of Health Sciences Publications

Myelination and neurite outgrowth both occur during brain development, and their disturbance has been previously been implicated in the pathophysiology of schizophrenia. Leucine-rich repeat and immunoglobulin domain-containing protein (Lingo-1) is a potent negative regulator of axonal myelination and neurite extension. As co-factors of Lingo-1 signaling (Nogo receptor (NgR), With No Lysine (K) (WNK1) and Myelin transcription factor 1 (Myt1)) have been implicated in the genetics of schizophrenia, we explored for the first time the role of Lingo-1 signaling pathways in this disorder. Lingo-1 protein, together with its co-receptor and co-factor proteins NgR, tumor necrosis factor (TNF) receptor orphan Y (TROY ...


Beliefs About Causes Of Weight Gain, Effective Weight Gain Prevention Strategies, And Barriers To Weight Management In The Australian Population, Rachel Dryer, Nicole Ware Jan 2014

Beliefs About Causes Of Weight Gain, Effective Weight Gain Prevention Strategies, And Barriers To Weight Management In The Australian Population, Rachel Dryer, Nicole Ware

Faculty of Health Sciences Publications

Purpose: To identify beliefs held by the general public regarding causes of weight gain, weight prevention strategies, and barriers to weight management; and to examine whether such beliefs predict the actual body mass of participants.
Methods: A questionnaire-based survey was administered to participants recruited from regional and metropolitan areas of Australia. This questionnaire obtained demographic information, height, weight; as well as beliefs about causes of weight gain, weight prevention strategies, and barriers to weight management.
Results: The sample consisted of 376 participants (94 males, 282 females) between the ages of 18 years and 88 years (mean age = 43.25, SD ...


Monitoring Training Load To Understand Fatigue In Athletes, Shona Halson Jan 2014

Monitoring Training Load To Understand Fatigue In Athletes, Shona Halson

Faculty of Health Sciences Publications

Many athletes, coaches, and support staff are taking an increasingly scientific approach to both designing and monitoring training programs. Appropriate load monitoring can aid in determining whether an athlete is adapting to a training program and in minimizing the risk of developing non-functional overreaching, illness, and/or injury. In order to gain an understanding of the training load and its effect on the athlete, a number of potential markers are available for use. However, very few of these markers have strong scientific evidence supporting their use, and there is yet to be a single, definitive marker described in the literature ...


Urinary And Breast Milk Biomarkers To Assess Exposure To Naphthalene In Pregnant Women: An Investigation Of Personal And Indoor Air Sources, Amanda Wheeler, Nina A. F. Dobbin, Marie-Eve Heroux, Mandy Fisher, Liu Sun, Cheryl F. Khoury, Russ Hauser, Mark Walker, Tim Ramsay, Jean-Francois Bienvenu, Alain Leblanc, Eric Daigle, Eric Gaudreau, Patrick Belanger, Mark Feeley, Pierre Ayotte, Tye E. Arbuckle Jan 2014

Urinary And Breast Milk Biomarkers To Assess Exposure To Naphthalene In Pregnant Women: An Investigation Of Personal And Indoor Air Sources, Amanda Wheeler, Nina A. F. Dobbin, Marie-Eve Heroux, Mandy Fisher, Liu Sun, Cheryl F. Khoury, Russ Hauser, Mark Walker, Tim Ramsay, Jean-Francois Bienvenu, Alain Leblanc, Eric Daigle, Eric Gaudreau, Patrick Belanger, Mark Feeley, Pierre Ayotte, Tye E. Arbuckle

Faculty of Health Sciences Publications

Background
Naphthalene exposures for most non-occupationally exposed individuals occur primarily indoors at home. Residential indoor sources include pest control products (specifically moth balls), incomplete combustion such as cigarette smoke, woodstoves and cooking, some consumer and building products, and emissions from gasoline sources found in attached garages. The study aim was to assess naphthalene exposure in pregnant women from Canada, using air measurements and biomarkers of exposure.
Methods
Pregnant women residing in Ottawa, Ontario completed personal and indoor air sampling, and questionnaires. During pregnancy, pooled urine voids were collected over two 24-hour periods on a weekday and a weekend day. At ...


The Human Early-Life Exposome (Helix): Project Rationale And Design, Martine Vrijheid, Rémy Slama, Oliver Robinson, Leda Chatzi, Muireann Coen, Peter Van Den Hazel, Cathrine Thomsen, John Wright, Toby J. Athersuch, Narcis Avellana, Xavier Basagaña, Celine Brochot, Luca Bucchini, Mariona Bustamante, Angel Carracedo, Maribel Casas, Xavier Estivill, Lesley Fairley, Diana Van Gent, Juan R. González, Berit Granum, Regina Gražulevičienė, Kristine B. Gutzkow, Jordi Julvez, Hector C. Keun, Manolis Kogevinas, Rosemary R. C. Mceachan, Helle Margrete Meltzer, Eduard Sabidó, Per E. Schwarze, Valérie Siroux, Jordi Sunyer, Elizabeth J. Want, Florence Zeman, Mark J. Nieuwenhuijsen Jan 2014

The Human Early-Life Exposome (Helix): Project Rationale And Design, Martine Vrijheid, Rémy Slama, Oliver Robinson, Leda Chatzi, Muireann Coen, Peter Van Den Hazel, Cathrine Thomsen, John Wright, Toby J. Athersuch, Narcis Avellana, Xavier Basagaña, Celine Brochot, Luca Bucchini, Mariona Bustamante, Angel Carracedo, Maribel Casas, Xavier Estivill, Lesley Fairley, Diana Van Gent, Juan R. González, Berit Granum, Regina Gražulevičienė, Kristine B. Gutzkow, Jordi Julvez, Hector C. Keun, Manolis Kogevinas, Rosemary R. C. Mceachan, Helle Margrete Meltzer, Eduard Sabidó, Per E. Schwarze, Valérie Siroux, Jordi Sunyer, Elizabeth J. Want, Florence Zeman, Mark J. Nieuwenhuijsen

Faculty of Health Sciences Publications

Background: Developmental periods in early life may be particularly vulnerable to impacts of environmental exposures. Human research on this topic has generally focused on single exposure–health effect relationships. The “exposome” concept encompasses the totality of exposures from conception onward, complementing the genome. Objectives: The Human Early-Life Exposome (HELIX) project is a new collaborative research project that aims to implement novel exposure assessment and biomarker methods to characterize early-life exposure to multiple environmental factors and associate these with omics biomarkers and child health outcomes, thus characterizing the “early-life exposome.” Here we describe the general design of the project. Methods: In ...


Visual Network Asymmetry And Default Mode Network Function In Adhd : An Fmri Study, T. Sigi Hale, Andrea M. Kane, Olivia Kaminsky, Kelly L. Tung, Joshua F. Wiley, James J. Mcgough, Sandra K. Loo, Jonas T. Kaplan Jan 2014

Visual Network Asymmetry And Default Mode Network Function In Adhd : An Fmri Study, T. Sigi Hale, Andrea M. Kane, Olivia Kaminsky, Kelly L. Tung, Joshua F. Wiley, James J. Mcgough, Sandra K. Loo, Jonas T. Kaplan

Faculty of Health Sciences Publications

Background: A growing body of research has identified abnormal visual information processing in attention-deficit hyperactivity disorder (ADHD). In particular, slow processing speed and increased reliance on visuo-perceptual strategies have become evident.

Objective: The current study used recently developed fMRI methods to replicate and further examine abnormal rightward biased visual information processing in ADHD and to further characterize the nature of this effect; we tested its association with several large-scale distributed network systems.

Method: We examined fMRI BOLD response during letter and location judgment tasks, and directly assessed visual network asymmetry and its association with large-scale networks using both a voxelwise ...


Quality In Acute Stroke Care (Qasc): Process Evaluation Of An Intervention To Improve The Management Of Fever, Hyperglycaemia And Swallowing Dysfunction Following Acute Stroke, Peta Drury, Chris Levi, Catherine D'Este, Patrick Mcelduff, Elizabeth Mcinnes, Jennifer Hardy, Simeon Dale, N Wah Cheung, Jeremy Grimshaw, Clare Quinn Jan 2014

Quality In Acute Stroke Care (Qasc): Process Evaluation Of An Intervention To Improve The Management Of Fever, Hyperglycaemia And Swallowing Dysfunction Following Acute Stroke, Peta Drury, Chris Levi, Catherine D'Este, Patrick Mcelduff, Elizabeth Mcinnes, Jennifer Hardy, Simeon Dale, N Wah Cheung, Jeremy Grimshaw, Clare Quinn

Faculty of Health Sciences Publications

Background

Our randomized controlled trial of a multifaceted evidence-based intervention for improving the inpatient management of fever, hyperglycemia, and swallowing dysfunction in the first three-days following stroke improved outcomes at 90 days by 15%. We designed a quantitative process evaluation to further explain and illuminate this finding.

Methods

Blinded retrospective medical record audits were undertaken for patients from 19 stroke units prior to and following the implementation of three multidisciplinary evidence-based protocols (supported by team-building workshops, and site-based education and support) for the management of fever (temperature ≥37·5°C), hyperglycemia (glucose >11 mmol/l), and swallowing dysfunction in intervention ...


Australian Alcohol Policy 2001-2013 And Implications For Public Health, Stephen Howard, Ross Gordon, Sandra Jones Jan 2014

Australian Alcohol Policy 2001-2013 And Implications For Public Health, Stephen Howard, Ross Gordon, Sandra Jones

Faculty of Education and Arts Publications

Background

Despite a complex and multi-faceted alcohol policy environment in Australia, there are few comprehensive reviews of national and state alcohol policies that assess their effectiveness and research support. In mapping the Australian alcohol policy domain and evaluating policy interventions in each of the core policy areas, this article provides a useful resource for researchers. The implications for protecting public health emanating from this mapping and evaluation of alcohol policy are also discussed.

Methods

This review considered data from: published primary research; alcohol legislation, strategies and alcohol-related press releases for all levels and jurisdictions of Australian government; international publications by ...


An Evaluation Of An Integrated Health Management Program For Workers In Hospital Setting, Toni M. Ryan Jan 2014

An Evaluation Of An Integrated Health Management Program For Workers In Hospital Setting, Toni M. Ryan

Theses

The aims of this study were to evaluate the 1) processes and 2) outcomes of a workplace health management program that attempted to integrate best practice principles of both workplace health promotion and injury management into the existing health management infrastructure of a major metropolitan hospital to improve the health management practices of hospital workers. An escalation in workplace injuries and a surfeit of injured workers who lacked the functional capacity to return to work had resulted in a shortage of skilled workers in this acute surgical hospital. This provided the impetus for the organisation to review its approach to ...


Prevalence And Correlates Of Attention Deficit Hyperactivity Disorder In Adults From A French Community Sample, Alexandre Morin, Herve Caci, Antoine Tran Jan 2014

Prevalence And Correlates Of Attention Deficit Hyperactivity Disorder In Adults From A French Community Sample, Alexandre Morin, Herve Caci, Antoine Tran

Faculty of Health Sciences Publications

Validated tools are lacking in languages like French to diagnose ADHD in adults. The Adult ADHD symptoms Self-Report (ASRS) was filled out by 1,171 parents of 900 school-aged youths in the context of the Children and Parents with ADHD and Related Disorders study. Prevalence estimates based on three scoring methods are compared (6-item screener, all 18 items, or the screener followed by the 12 remaining items). Based on the recommended and more conservative scoring method, the overall prevalence of ADHD symptoms is estimated to be 2.99%, without significant group differences between genders, or between younger and older adults ...


Efficacy And Safety Of Oral Methazolamide In Patients With Type 2 Diabetes: A 24-Week, Placebo-Controlled, Double-Blind Study, Richard W. Simpson, Geoffrey C. Nicholson, Joseph Proietto, Alana Sarah, Kerrie M. Sanders, Gabrielle Phillips, Jo Chambers, Rob Macginley, Neil Orford, Ken Walder, Guy Krippner, Kathy Skoff, Vincent J. Wacher Jan 2014

Efficacy And Safety Of Oral Methazolamide In Patients With Type 2 Diabetes: A 24-Week, Placebo-Controlled, Double-Blind Study, Richard W. Simpson, Geoffrey C. Nicholson, Joseph Proietto, Alana Sarah, Kerrie M. Sanders, Gabrielle Phillips, Jo Chambers, Rob Macginley, Neil Orford, Ken Walder, Guy Krippner, Kathy Skoff, Vincent J. Wacher

Faculty of Health Sciences Publications

OBJECTIVE To evaluate the safety and efficacy of methazolamide as a potential therapy for type 2 diabetes. RESEARCH DESIGN AND METHODS This double-blind, placebo-controlled study randomized 76 patients to oral methazolamide (40 mg b.i.d.) or placebo for 24 weeks. The primary efficacy end point for methazolamide treatment was a placebo-corrected reduction in HbA1c from baseline after 24 weeks (ΔHbA1c). RESULTS Mean ± SD baseline HbA1c was 7.1 ± 0.7% (54 ± 5 mmol/mol; n = 37) and 7.4 ± 0.6% (57 ± 5 mmol/mol; n = 39) in the methazolamide and placebo groups, respectively. Methazolamide treatment was associated with ...


A Mixed Methods Study Of Collaboration Between Perinatal And Infant Mental Health Clinicians And Other Service Providers: Do They Sit In Silos?, Karen A. Myors, Michelle Cleary, Maree Johnson, Virginia Schmied Jan 2014

A Mixed Methods Study Of Collaboration Between Perinatal And Infant Mental Health Clinicians And Other Service Providers: Do They Sit In Silos?, Karen A. Myors, Michelle Cleary, Maree Johnson, Virginia Schmied

Faculty of Health Sciences Publications

Background Women at risk of poor perinatal mental health benefit from coordinated approaches to care. Perinatal and infant mental health (PIMH) services have been established to support women with social and emotional needs. This paper examines the nature and extent of collaboration within two PIMH services in Australia. Methods A convergent, embedded, mixed methods design was used. Two hundred and forty four medical records were reviewed, 13 professionals (six PIMH clinicians, two PIMH service managers, and five key stakeholders) and 11 women service-users participated in semi-structured interviews. Results Three broad themes were drawn from the data, Theme 1: We don ...