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Australian Catholic University

2011

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Full-Text Articles in Medicine and Health Sciences

Working It Out: New Mothers' Experiences Of Learning To Breasfeed, Danielle Gleeson Dec 2011

Working It Out: New Mothers' Experiences Of Learning To Breasfeed, Danielle Gleeson

Theses

The aim of this study was to explore new mothers' experiences of receiving breastfeeding support from midwives. The study's objectives were to identify, describe and explain the role of the midwife in supporting new mothers to breastfeed, the factors that influenced new mothers' experiences of receiving breastfeeding support from midwives and the impact of midwifery practices on new mothers' experiences of receiving breastfeeding support.


The Enduring Effects Of Job Demands On The Mental Health Of Police Officers, Katrina J. Lawson Dec 2011

The Enduring Effects Of Job Demands On The Mental Health Of Police Officers, Katrina J. Lawson

Theses

Occupational stress research has consistently documented significant relationships between work characteristics and employee mental health, with the components of the Demand-Control-Support (DCS) model of occupational stress (i.e., job demand, job control and social support) being widely used to capture work characteristics (Karasek & Theorell, 1990). The work characteristics of the DCS model appear to be key determinants of employee health outcomes for individuals in a diverse range of occupations (de Lange, Taris, Kompier, Houtman, & Bongers, 2003; van der Doef & Maes, 1999). Although previous research suggests that the DCS model may provide a strong foundation for investigating the effects of the work environment on employee health, the model does not, however, consider the possible effects of the broader organisational context on the health of employees. In light of this criticism, a growing body of research in the last decade (Fujishiro & Heaney, 2007) has begun to compare the influence of work characteristics, as measured by the DCS model, with a concept known as 'organisational justice' in order to broaden the focus of the DCS model and to account for the organisational environment (e.g. Elovainio, Kivimaki, & Vahtera, 2002; Kivimaki, et al., 2005; Kivimaki, et al., 2004; Zohar, 1995). Preliminary results from studies that have compared the effects of work characteristics and organisational justice onto health outcomes tend to indicate that justice is a stronger antecedent of employee mental health than work characteristics. Research studies incorporating both work characteristics and justice are relatively ...


Applications Of Portable Tracking Technology To Talent Development In Team Sports, Darren Burgess Dec 2011

Applications Of Portable Tracking Technology To Talent Development In Team Sports, Darren Burgess

Theses

Despite widespread current availability of motion analysis techniques in sport, little attention has been given to how the devices can be used to understand more about the gap between aspiring elite and elite team sport. Therefore, the purpose of this thesis was to explore a number of applications of tracking technology, specifically Global Positioning Satellite (GPS) devices, to the development of talent within team sport. This Thesis by Publication consists of 4 publications. The first publication provided a review of relevant literature and practices of talent development within team sports in Australia. Study one profiled the movement demands of professional ...


Evaluation Of The Barwon South Western Region Dementia Strategy, Briony Dow, Emma Renehan, Colleen Doyle Nov 2011

Evaluation Of The Barwon South Western Region Dementia Strategy, Briony Dow, Emma Renehan, Colleen Doyle

Faculty of Health Sciences Publications

The Department of Health (DH) Barwon-South Western (BSW) Region Dementia Strategy was developed with the support of regional health professionals in response to the Regional, State and National Health Departments’ priority to improve services for people affected by dementia. The National Ageing Research Institute (NARI) was commissioned by DH BSW in 2010 to conduct an evaluation of the BSW Region Dementia Strategy.


Bachelor Of Midwifery Students' Experiences Of Achieving Competency For Beginning Practice, Sharon Licqurish Nov 2011

Bachelor Of Midwifery Students' Experiences Of Achieving Competency For Beginning Practice, Sharon Licqurish

Theses

This study, commencing in 2005, explored the experiences of Bachelor of Midwifery students' achievement of competency for beginning practice. Data were collected via interviews with nineteen final year Bachelor of Midwifery students, completed competency assessments and reflective journals, along with field observation of 5 of the students periodically during their final placement, for a total of 48 hours. Data were analysed using grounded theory methodology augmented by situational analysis. Achievement of competency involved a number of social processes as the students adapted to a largely medically dominated system. The overarching process was termed assimilation, linked to which were realisation, adaptation ...


A Qualitative Study Of Spanish-Speaking Patients’ Experiences Of Pain After Surgery, Nelly Beatriz Bruinsma Jun 2011

A Qualitative Study Of Spanish-Speaking Patients’ Experiences Of Pain After Surgery, Nelly Beatriz Bruinsma

Theses

The aim of this study was to acquire knowledge of the way Spanish-speaking patients experience pain and pain management after surgery and to analyse how their experiences, lack of knowledge of the English language and their cultural beliefs may influence their experiences. The study outcomes will assist health professionals to provide a culturally appropriate pain management plan when not able to speak English and to care appropriately for Spanish-speaking patients and for other Culturally and Linguistically Diverse (CALD) patients. An interpretive phenomenological approach informed by Gadamer’s (1979) theory was used to explore seven participants ‘in-depth stories.’ The study sought ...


Upper Body Bone Strength And Muscle Function In Non-Elite Artistic Gymnasts, Lauren A. Burt May 2011

Upper Body Bone Strength And Muscle Function In Non-Elite Artistic Gymnasts, Lauren A. Burt

Theses

Musculoskeletal development in the upper limbs of non-elite female gymnasts during pre and early pubescent growth is under researched. Most studies have focussed on elite rather than non-elite gymnasts, via dual-energy X-ray absorptiometry (DXA). The purpose of this thesis was to longitudinally characterise the effects of non-elite female artistic gymnastics participation on upper limb musculoskeletal parameters using peripheral Quantitative Computed Tomography (pQCT), DXA and muscle function assessments. Three major studies were designed. Study one compared the upper limb of two groups of gymnasts (high-training gymnasts (HGYM), participating in 6-16 hr/wk, low-training gymnasts (LGYM), participating in 1-5 hr/wk) and ...


Evaluation Of Nursing Students' Academic Expectations, Perceptions And Experiences Of Science At Different Stages During Their Undergraduate Studies, Hemant Mehta Apr 2011

Evaluation Of Nursing Students' Academic Expectations, Perceptions And Experiences Of Science At Different Stages During Their Undergraduate Studies, Hemant Mehta

Theses

At the Australian Catholic University (NSW), expansion of the undergraduate nursing program in response to a worldwide shortage of nurses resulted in increased student enrolment and accelerated diversification of the student population during the study period, 2005 to 2009. A primary focus of this investigation was to develop a better understanding of this nursing student population, and evaluate the impact of rapid unplanned change on the academic environment by exploring students' changing expectations, perceptions and experiences of science during the BN course. The research design combined a horizontal three year study with a three year longitudinal investigation. The repetitive horizontal ...


Musculoskeletal Kinetic Models To Predict Injury And Performance In Adolescent Female Athletes, Mark Peter Moresi Apr 2011

Musculoskeletal Kinetic Models To Predict Injury And Performance In Adolescent Female Athletes, Mark Peter Moresi

Theses

Background: High level adolescent female athletes in high-impact sports may be at an increased injury risk due to increased training demands coupled with pubertal growth. Participation longevity in active females requires innovative, holistic research to advance the understanding of injury prevention via longitudinal training response monitoring. Measures of musculoskeletal stiffness (MSS), which model the lower limb as a spring, may provide valuable insight on this issue. MSS has been linked to both performance and injury through cross-sectional and retrospective study designs. This thesis aimed to longitudinally investigate measures of MSS, jump performance and injury in adolescent females from high-impact, low-impact ...


The Experiences Of Parents And Nurses Of Hospitalised Infants Requiring Oxygen Therapy For Severe Bronchiolitis: A Phenomenological Study, Alison Peeler Mar 2011

The Experiences Of Parents And Nurses Of Hospitalised Infants Requiring Oxygen Therapy For Severe Bronchiolitis: A Phenomenological Study, Alison Peeler

Theses

Objectives: Annually, bronchiolitis is a major cause of children's hospital admissions. Children suffering from respiratory distress are provided supplemental oxygen therapy via a headbox. Whilst effective in treating the child physically, the headbox can be very restrictive and limits parental access to their child. This form of oxygen therapy can have a detrimental effect on parental bonding, their relationship with their child, and the parents' ability to fulfil their parenting role. The aim of this study was to investigate the lived experiences of parents and nurses who have had or cared for a child admitted to hospital for severe ...


A Multilevel Investigation Of Inequalities In Clinical And Psychosocial Outcomes For Women After Breast Cancer, Philippa H. Youl, Peter D. Baade, Joanne Aitken, Suzanne K. Chambers, Gavin Turrell, Christopher Pyke, Jeffery Dunn Jan 2011

A Multilevel Investigation Of Inequalities In Clinical And Psychosocial Outcomes For Women After Breast Cancer, Philippa H. Youl, Peter D. Baade, Joanne Aitken, Suzanne K. Chambers, Gavin Turrell, Christopher Pyke, Jeffery Dunn

Faculty of Health Sciences Publications

Background In Australia, breast cancer is the most common cancer affecting Australian women. Inequalities in clinical and psychosocial outcomes have existed for some time, affecting particularly women from rural areas and from areas of disadvantage. We have a limited understanding of how individual and area-level factors are related to each other, and their associations with survival and other clinical and psychosocial outcomes. Methods/Design This study will examine associations between breast cancer recurrence, survival and psychosocial outcomes (e.g. distress, unmet supportive care needs, quality of life). The study will use an innovative multilevel approach using area-level factors simultaneously with ...


An Exploration Of Factors That Influence End Of Career Nurses' Decision Making Regarding Their Workforce Participation, Catriona Anne Booker Jan 2011

An Exploration Of Factors That Influence End Of Career Nurses' Decision Making Regarding Their Workforce Participation, Catriona Anne Booker

Theses

As healthcare faces a critical shortage of qualified nursing staff, the ageing nursing workforce is further challenged as the 'Baby Boomer' generation approaches retirement age by 2010. While current retention strategies are focused on recruitment, little is known about the reasons for the end of career nurses' (EOCNs') premature retirement or their resilience to remain in the profession. For the purpose of this thesis, the term EOCN is defined as registered nurses aged from 45 years and above, regardless of their length of service in the profession. The purpose of this research is to explore factors that influence EOCNs' decisions ...


Exercise-Induced Splanchnic Hypoperfusion Results In Gut Dysfunction In Healthy Men, Kim V. Wijck, Kaatje Lenaerts, Luc Van Loon, Wilbert H. M. Peters, Wim A. Buurman, Cornelis H. C. Dejong Jan 2011

Exercise-Induced Splanchnic Hypoperfusion Results In Gut Dysfunction In Healthy Men, Kim V. Wijck, Kaatje Lenaerts, Luc Van Loon, Wilbert H. M. Peters, Wim A. Buurman, Cornelis H. C. Dejong

Faculty of Health Sciences Publications

Background Splanchnic hypoperfusion is common in various pathophysiological conditions and often considered to lead to gut dysfunction. While it is known that physiological situations such as physical exercise also result in splanchnic hypoperfusion, the consequences of flow redistribution at the expense of abdominal organs remained to be determined. This study focuses on the effects of splanchnic hypoperfusion on the gut, and the relationship between hypoperfusion, intestinal injury and permeability during physical exercise in healthy men. Methods and Findings Healthy men cycled for 60 minutes at 70% of maximum workload capacity. Splanchnic hypoperfusion was assessed using gastric tonometry. Blood, sampled every ...


Heart Failure: Not Enough Pump Iron?, John J. V. Mcmurray, Piotr P. Ponikowski Jan 2011

Heart Failure: Not Enough Pump Iron?, John J. V. Mcmurray, Piotr P. Ponikowski

Faculty of Health Sciences Publications

No abstract provided.


Evaluation Of A Resistance Training Program For Adults With Or At Risk Of Developing Diabetes : An Effectiveness Study In A Community Setting, Karl Minges, Glen Cormick, Edna Unglik, David Dunstan Jan 2011

Evaluation Of A Resistance Training Program For Adults With Or At Risk Of Developing Diabetes : An Effectiveness Study In A Community Setting, Karl Minges, Glen Cormick, Edna Unglik, David Dunstan

Faculty of Health Sciences Publications

Background: To examine the effects of a community-based resistance training program (Lift for Life®) on waist circumference and functional measures in adults with or at risk of developing type 2 diabetes. Methods: Lift for Life is a research-to-practice initiative designed to disseminate an evidence-based resistance training program for adults with or at risk of developing type 2 diabetes to existing health and fitness facilities in the Australian community. A retrospective assessment was undertaken on 86 participants who had accessed the program within 4 active providers in Melbourne, Australia. The primary goal of this longitudinal study was to assess the effectiveness ...


Objectively Measured Physical Activity And The Subsequent Risk Of Incident Dysglycemia : The Australian Diabetes, Obesity And Lifestyle Study (Ausdiab), Anne-Louise Ponsonby, Cong Sun, Obioha Ukoumunne, Angela Pezic, Alison Venn, Jonathan Shaw, David Dunstan, Elizabeth Barr, Steven Blair, Jenny Cochrane, Paul Zimmet, Terence Dwyer Jan 2011

Objectively Measured Physical Activity And The Subsequent Risk Of Incident Dysglycemia : The Australian Diabetes, Obesity And Lifestyle Study (Ausdiab), Anne-Louise Ponsonby, Cong Sun, Obioha Ukoumunne, Angela Pezic, Alison Venn, Jonathan Shaw, David Dunstan, Elizabeth Barr, Steven Blair, Jenny Cochrane, Paul Zimmet, Terence Dwyer

Faculty of Health Sciences Publications

Objective: To investigate pedometer-measured physical activity (PA) in 2000 and change in PA over 5 years with subsequent risk of dysglycemia by 2005. Research design and methods: This prospective cohort study in Tasmania, Australia, analyzed 458 adults with normal glucose tolerance and a mean (SD) age of 49.7 (12.1) years in 2000. Variables assessed in 2000 and 2005 included PA, by pedometer and questionnaire, nutrient intake, and other lifestyle factors. Incident dysglycemia was defined as the development of impaired fasting glucose or impaired glucose tolerance revealed by oral glucose tolerance testing in 2005, without type 2 diabetes. Results ...


Does Passive Mobilization Of Shoulder Region Joints Provide Additional Benefit Over Advice And Exercise Alone For People Who Have Shoulder Pain And Minimal Movement Restriction? A Randomized Controlled Trial, Ross Yiasemides, Mark Halaki, Ian Cathers, Karen Ginn Jan 2011

Does Passive Mobilization Of Shoulder Region Joints Provide Additional Benefit Over Advice And Exercise Alone For People Who Have Shoulder Pain And Minimal Movement Restriction? A Randomized Controlled Trial, Ross Yiasemides, Mark Halaki, Ian Cathers, Karen Ginn

Faculty of Health Sciences Publications

Background: Passive mobilization of shoulder region joints, often in conjunction with other treatment modalities, is used for the treatment of people with shoulder pain and minimal movement restriction. However, there is only limited evidence supporting the efficacy of this treatment modality. Objective: The purpose of this study was to determine whether passive mobilization of shoulder region joints adds treatment benefit over exercise and advice alone for people with shoulder pain and minimal movement restriction. Design: This was a randomized controlled clinical trial with short-, medium- and longer-term follow-up. Setting: The study was conducted in a metropolitan teaching hospital. Patients: Ninety-eight ...


Efficacy And Safety Of A Modular Multi-Modal Exercise Program In Prostate Cancer Patients With Bone Metastases: A Randomized Controlled Trial, Daniel Galvao, D R Taaffe, P Cormie, Nigel Spry, Suzanne Chambers, C Peddle-Mcintyre, Michael Baker, James Denham, David Joseph, Geoff Groom Jan 2011

Efficacy And Safety Of A Modular Multi-Modal Exercise Program In Prostate Cancer Patients With Bone Metastases: A Randomized Controlled Trial, Daniel Galvao, D R Taaffe, P Cormie, Nigel Spry, Suzanne Chambers, C Peddle-Mcintyre, Michael Baker, James Denham, David Joseph, Geoff Groom

Faculty of Health Sciences Publications

Background

The presence of bone metastases has excluded participation of prostate cancer patients in exercise intervention studies to date and is also a relative contraindication to supervised exercise in the community setting because of concerns of fragility fracture. However, this group of patients often have developed significant muscle atrophy and functional impairments from prior and continuing androgen deprivation that is exacerbated by subsequent and more intensive interventions such as chemotherapy. The aim of this study is to determine the efficacy and safety of a modular multi-modal exercise program in prostate cancer patients with bone metastases.

Methods/Design

Multi-site randomized controlled ...


Women With Heart Failure Are At High Psychosocial Risk: A Systematic Review Of How Sex And Gender Influence Heart Failure Self-Care, Jody R. Thomas, Alexander M. Clark Jan 2011

Women With Heart Failure Are At High Psychosocial Risk: A Systematic Review Of How Sex And Gender Influence Heart Failure Self-Care, Jody R. Thomas, Alexander M. Clark

Faculty of Health Sciences Publications

No abstract provided.


Trends In Incidence And In Short Term Survival Following A Subarachnoid Haemorrhage In Scotland, 1986 - 2005: A Retrospective Cohort Study, Karen J. Macpherson, James D. Lewsey, Pardeep S. Jhund, Michelle Gillies, Jim Wt Chalmers, Adam Redpath, Andrew Briggs, Matthew Walters, Peter Langhorne, Simon Capewell, John Jv Mcmurray, Kate Macintyre Jan 2011

Trends In Incidence And In Short Term Survival Following A Subarachnoid Haemorrhage In Scotland, 1986 - 2005: A Retrospective Cohort Study, Karen J. Macpherson, James D. Lewsey, Pardeep S. Jhund, Michelle Gillies, Jim Wt Chalmers, Adam Redpath, Andrew Briggs, Matthew Walters, Peter Langhorne, Simon Capewell, John Jv Mcmurray, Kate Macintyre

Faculty of Health Sciences Publications

Background: To examine age and sex specific incidence and 30 day case fatality for subarachnoid haemorrhage (SAH) in Scotland over a 20 year period.


Association Of Plasma Aß Peptides With Blood Pressure In The Elderly, Jean C. Lambert, Jean Dallongeville, Kathryn A. Ellis, Susanna Schraen-Maschke, James Lui, Simon M. Laws, Julie Dumont, Florence Richard, Dominique C. Cottel, Claudine Berr, David Ames, Colin L. Masters, Christopher C. Rowe, Cassandra Szoeke, Christophe Tzourio, Jean-Francois Dartigues, Luc Buee, Ralph N. Martins, Phillippe Amouyel Jan 2011

Association Of Plasma Aß Peptides With Blood Pressure In The Elderly, Jean C. Lambert, Jean Dallongeville, Kathryn A. Ellis, Susanna Schraen-Maschke, James Lui, Simon M. Laws, Julie Dumont, Florence Richard, Dominique C. Cottel, Claudine Berr, David Ames, Colin L. Masters, Christopher C. Rowe, Cassandra Szoeke, Christophe Tzourio, Jean-Francois Dartigues, Luc Buee, Ralph N. Martins, Phillippe Amouyel

Faculty of Health Sciences Publications

Background: Aß peptides are often considered as catabolic by-products of the amyloid ß protein precursor (APP), with unknown physiological functions. However, several biological properties have been tentatively attributed to these peptides, including a role in vasomotion. We assess whether plasma Aß peptide levels might be associated with systolic and diastolic blood pressure values (SBP and DBP, respectively). Methodology/Principal Findings: Plasma Aß1-40 and Aß1-42 levels were measured using an xMAP-based assay in 1,972 individuals (none of whom were taking antihypertensive drugs) from 3 independent studies: the French population-based 3C and MONA-LISA (Lille) studies (n = 627 and n = 769, respectively ...


Cost-Effectiveness Of Dermabond Versus Sutures For Lacerated Wound Closure: A Randomised Controlled Trial, Mi Ling Eliza Wong, T. H. Rainer, Yan Lam Ng, M. S. Chan, Violeta Lopez Jan 2011

Cost-Effectiveness Of Dermabond Versus Sutures For Lacerated Wound Closure: A Randomised Controlled Trial, Mi Ling Eliza Wong, T. H. Rainer, Yan Lam Ng, M. S. Chan, Violeta Lopez

Faculty of Health Sciences Publications

1. For management of simple lacerated wounds, tissue adhesive (Dermabond) achieved more positive outcomes but incurred higher cost, compared with standard sutures. 2. Dermabond may be more cost-effective than standard sutures from a societal viewpoint. 3. Use of sutures required more nursing time and additional costs from subsequent dressing, whereas use of Dermabond incurred higher equipment costs. 4. Dermabond achieved better appearance outcome and patient satisfaction, compared with sutures. 5. Pain levels were not significantly different in patients treated with Dermabond or sutures.


Validation Of De-Identified Record Linkage To Ascertain Hospital Admissions In A Cohort Study, Allison Beauchamp, Andrew Tonkin, Helen Kelsall, Vijaya Sundararajan, Dallas English, Lalitha Sundaresan, Rory Wolfe, Gavin Turrell, Graham G. Giles, A. Peeters Jan 2011

Validation Of De-Identified Record Linkage To Ascertain Hospital Admissions In A Cohort Study, Allison Beauchamp, Andrew Tonkin, Helen Kelsall, Vijaya Sundararajan, Dallas English, Lalitha Sundaresan, Rory Wolfe, Gavin Turrell, Graham G. Giles, A. Peeters

Faculty of Health Sciences Publications

Background Cohort studies can provide valuable evidence of cause and effect relationships but are subject to loss of participants over time, limiting the validity of findings. Computerised record linkage offers a passive and ongoing method of obtaining health outcomes from existing routinely collected data sources. However, the quality of record linkage is reliant upon the availability and accuracy of common identifying variables. We sought to develop and validate a method for linking a cohort study to a state-wide hospital admissions dataset with limited availability of unique identifying variables. Methods A sample of 2000 participants from a cohort study (n = 41 ...


Swahili-Based Concepts: Explaining How Social Ties Manage Hiv And Infant Feeding, Jean Burke Jan 2011

Swahili-Based Concepts: Explaining How Social Ties Manage Hiv And Infant Feeding, Jean Burke

Faculty of Education and Arts Publications

In Tanzania where HIV transmission is high, decisions to avoid or modify breastfeeding are crucial for infant survival yet difficult due to competing risks. A study in Central Tanzania explored the role of social dynamics in infant feeding decisions to prevent HIV. Qualitative data was collected from in-depth interviews and focus group discussions with people living with HIV and community members, including village leaders, traditional healers and midwives within the Dodoma region. Data was analysed using grounded theory and natural Swahili language.

Emerging themes were based on Swahili categorisations. In the context of HIV, infant feeding is a moral issue ...


Implementation Of Evidence-Based Treatment Protocols To Manage Fever, Hyperglycaemia, And Swallowing Dysfunction In Acute Stroke (Qasc) :A Cluster Randomised Controlled Trial, Sandy Middleton, P. Mcelduff, J. Ward, J. Grimshaw, S. Dale, C. D'Este, P. Drury, R. Griffiths, N. Cheung, C. Quinn, M. Evans, D. Cadilhac, C. Levi Jan 2011

Implementation Of Evidence-Based Treatment Protocols To Manage Fever, Hyperglycaemia, And Swallowing Dysfunction In Acute Stroke (Qasc) :A Cluster Randomised Controlled Trial, Sandy Middleton, P. Mcelduff, J. Ward, J. Grimshaw, S. Dale, C. D'Este, P. Drury, R. Griffiths, N. Cheung, C. Quinn, M. Evans, D. Cadilhac, C. Levi

Faculty of Health Sciences Publications

Background

We assessed patient outcomes 90 days after hospital admission for stroke following a multidisciplinary intervention targeting evidence-based management of fever, hyperglycaemia, and swallowing dysfunction in acute stroke units (ASUs).

Methods

In the Quality in Acute Stroke Care (QASC) study, a single-blind cluster randomised controlled trial, we randomised ASUs (clusters) in New South Wales, Australia, with immediate access to CT and on-site high dependency units, to intervention or control group. Patients were eligible if they spoke English, were aged 18 years or older, had had an ischaemic stroke or intracerebral haemorrhage, and presented within 48 h of onset of symptoms ...


Factors Associated With Outcome In Heart Failure With Preserved Ejection Fraction : Findings From The Irbesartan In Heart Failure With Preserved Ejection Fraction Study (I-Preserve), Michel Komajda, Peter E. Carson, Scott J. Hetzel, Robert Mckelvie, John Mcmurray, Agata Ptaszynska, Michael R. Zile, David Demets, Barry M. Massie Jan 2011

Factors Associated With Outcome In Heart Failure With Preserved Ejection Fraction : Findings From The Irbesartan In Heart Failure With Preserved Ejection Fraction Study (I-Preserve), Michel Komajda, Peter E. Carson, Scott J. Hetzel, Robert Mckelvie, John Mcmurray, Agata Ptaszynska, Michael R. Zile, David Demets, Barry M. Massie

Faculty of Health Sciences Publications

The determinants of prognosis in patients with heart failure and preserved ejection fraction (HF-PEF) are poorly documented.


Relation Of Peripheral Collagen Markers To Death And Hospitalization In Patients With Heart Failure And Preserved Ejection Fraction : Results Of The I-Preserve Collagen Substudy, Henry Krum, Maros Elsik, Hans G. Schneider, Agata Ptaszynska, Marion Black, Peter E. Carson, Michel Komajda, Barry Massie, Robert Mckelvie, John Mcmurray, Michael R. Zile, Inder S. Anand Jan 2011

Relation Of Peripheral Collagen Markers To Death And Hospitalization In Patients With Heart Failure And Preserved Ejection Fraction : Results Of The I-Preserve Collagen Substudy, Henry Krum, Maros Elsik, Hans G. Schneider, Agata Ptaszynska, Marion Black, Peter E. Carson, Michel Komajda, Barry Massie, Robert Mckelvie, John Mcmurray, Michael R. Zile, Inder S. Anand

Faculty of Health Sciences Publications

Heart failure with preserved ejection fraction (HFPEF) is a common and increasing public health problem. Myocardial fibrosis is a key pathological feature of HFPEF. Peripheral collagen markers may reflect this excess fibrosis; however, the relation of these markers to prognosis in patients with HFPEF has not as yet been determined.


Postprandial Hyperglycemia Is Highly Prevalent Throughout The Day In Type 2 Diabetes Patients, Jan-Willem Van Dijk, Ralph J. F. Manders, Fred Hartgens, Coen D. A. Stehouwer, Stephan F. E. Praet, Luc J. C. Van Loon Jan 2011

Postprandial Hyperglycemia Is Highly Prevalent Throughout The Day In Type 2 Diabetes Patients, Jan-Willem Van Dijk, Ralph J. F. Manders, Fred Hartgens, Coen D. A. Stehouwer, Stephan F. E. Praet, Luc J. C. Van Loon

Faculty of Health Sciences Publications

Aim: Although postprandial hyperglycemia is recognized as an important target in type 2 diabetes treatment, information on the prevalence of postprandial hyperglycemia throughout the day is limited. Therefore, we assessed the prevalence of hyperglycemia throughout the day in type 2 diabetes patients and healthy controls under standardized dietary, but otherwise free-living conditions. Methods: 60 male type 2 diabetes patients (HbA1c 7.5 ± 0.1% [58 ± 1 mmol/mol]) and 24 age- and BMI-matched normal glucose tolerant controls were recruited to participate in a comparative study of daily glycemic control. During a 3-day experimental period, blood glucose concentrations throughout the day ...


Stroke In Patients With Type 2 Diabetes Mellitus, Chronic Kidney Disease, And Anemia Treated With Darbepoetin Alfa: The Trial To Reduce Cardiovascular Events With Aranesp Therapy (Treat) Experience, Hicham Skali, Hans Henrik Parving, Patrick Parfrey, Emmanuel A. Burdmann, E. F. Lewis, Peter Ivanovich, Sai Ram Keithi-Reddy, Janet B. Mcgill, John Mcmurray, Ajay K. Singh, Scott Solomon, Hajime Uno, Marc A. Pfeffer Jan 2011

Stroke In Patients With Type 2 Diabetes Mellitus, Chronic Kidney Disease, And Anemia Treated With Darbepoetin Alfa: The Trial To Reduce Cardiovascular Events With Aranesp Therapy (Treat) Experience, Hicham Skali, Hans Henrik Parving, Patrick Parfrey, Emmanuel A. Burdmann, E. F. Lewis, Peter Ivanovich, Sai Ram Keithi-Reddy, Janet B. Mcgill, John Mcmurray, Ajay K. Singh, Scott Solomon, Hajime Uno, Marc A. Pfeffer

Faculty of Health Sciences Publications

More strokes were observed in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT) among patients assigned to darbepoetin alfa. We sought to identify baseline characteristics and postrandomization factors that might explain this association.


Prevalence And Significance Of Alterations In Cardiac Structure And Function In Patients With Heart Failure And A Preserved Ejection Fraction, Michael R. Zile, John S. Gottdiener, Scott J. Hetzel, John Mcmurray, Michel Komajda, Robert Mckelvie, Catalin F. Baicu, Barry M. Massie, Peter E. Carson Jan 2011

Prevalence And Significance Of Alterations In Cardiac Structure And Function In Patients With Heart Failure And A Preserved Ejection Fraction, Michael R. Zile, John S. Gottdiener, Scott J. Hetzel, John Mcmurray, Michel Komajda, Robert Mckelvie, Catalin F. Baicu, Barry M. Massie, Peter E. Carson

Faculty of Health Sciences Publications

The purpose of this study was to examine the prevalence of abnormalities in cardiac structure and function present in patients with heart failure and a preserved ejection fraction (HFPEF) and to determine whether these alterations in structure and function were associated with cardiovascular morbidity and mortality.