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Full-Text Articles in Medicine and Health Sciences

Should We Provide Outreach Rehabilitation To Very Old People Living In Nursing Care Facilities After A Hip Fracture? A Randomised Controlled Trial, Maria Crotty, Maggie Killington, Enwu Liu, Ian D. Cameron, Susan Kurrle, Billingsley Kaambwa, Owen Davies, Michelle D. Miller, Mellick Chehade, Julie Ratcliffe Jan 2019

Should We Provide Outreach Rehabilitation To Very Old People Living In Nursing Care Facilities After A Hip Fracture? A Randomised Controlled Trial, Maria Crotty, Maggie Killington, Enwu Liu, Ian D. Cameron, Susan Kurrle, Billingsley Kaambwa, Owen Davies, Michelle D. Miller, Mellick Chehade, Julie Ratcliffe

Faculty of Health Sciences Publications

Objective to determine whether a 4-week postoperative rehabilitation program delivered in Nursing Care Facilities (NCFs) would improve quality of life and mobility compared with receiving usual care. Design parallel randomised controlled trial with integrated health economic study. Setting NCFs, in Adelaide South Australia. Subjects people aged 70 years and older who were recovering from hip fracture surgery and were walking prior to hip fracture. Measurements primary outcomes: mobility (Nursing Home Life-Space Diameter (NHLSD)) and quality of life (DEMQOL) at 4 weeks and 12 months. Results participants were randomised to treatment (n = 121) or control (n = 119) groups. At 4 weeks ...


Trial Feasibility And Process Evaluation Of A Motivationally-Embellished Group Peer Led Walking Intervention In Retirement Villages Using The Re-Aim Framework: The Residents In Action Trial (Riat), Cecilie Thøgersen-Ntoumani, Eleanor Quested, Stuart J. H. Biddle, Marlene Kritz, Jenny Olson, Elissa Burton, Ester Cerin, Keith D. Hill, Joanne A. Mcveigh, Nikos Ntoumanis Jan 2019

Trial Feasibility And Process Evaluation Of A Motivationally-Embellished Group Peer Led Walking Intervention In Retirement Villages Using The Re-Aim Framework: The Residents In Action Trial (Riat), Cecilie Thøgersen-Ntoumani, Eleanor Quested, Stuart J. H. Biddle, Marlene Kritz, Jenny Olson, Elissa Burton, Ester Cerin, Keith D. Hill, Joanne A. Mcveigh, Nikos Ntoumanis

Faculty of Health Sciences Publications

Objective: The Residents in Action Trial (RiAT; ACTRN12616001177448) was a 16-week motivationally-embellished peer-led walking intervention designed to increase walking, reduce sitting, and improve mental health and well-being in insufficiently active residents in retirement villages. In this paper we report on 1) trial feasibility and acceptability, and 2) evaluate the processes involved in the implementation of the intervention using the RE-AIM framework. Method: A mixed methods design was employed, consisting of data from accelerometers, surveys, (individual, pair-based and focus group) interviews, and participant logbooks. Participants included 116 walkers (M(SD) age = 78.37(8.30); 92% female), 8 peer leaders (i ...


Dose-Response Association Between Physical Activity And Sedentary Time Categories On Ageing Biomarkers, Asier Mañas, Borja Del Pozo-Cruz, Irene Rodríguez-Gómez, Javier Leal-Martín, José Losa-Reyna, Leocadio Rodriguez Mañas, Francisco J. García-García, Ignacio Ara Jan 2019

Dose-Response Association Between Physical Activity And Sedentary Time Categories On Ageing Biomarkers, Asier Mañas, Borja Del Pozo-Cruz, Irene Rodríguez-Gómez, Javier Leal-Martín, José Losa-Reyna, Leocadio Rodriguez Mañas, Francisco J. García-García, Ignacio Ara

Faculty of Health Sciences Publications

Background: Physical activity and sedentary behaviour have been suggested to independently affect a number of health outcomes. To what extent different combinations of physical activity and sedentary behaviour may influence physical function and frailty outcomes in older adults is unknown. The aim of this study was to examine the combination of mutually exclusive categories of accelerometer-measured physical activity and sedentary time on physical function and frailty in older adults. Methods: 771 older adults (54% women; 76.8 ± 4.9 years) from the Toledo Study for Healthy Aging participated in this cross-sectional study. Physical activity and sedentary time were measured by ...


How Well Do Seniors Estimate Distance To Food? The Accuracy Of Older Adults' Reported Proximity To Local Grocery Stores, Benjamin W. Chrisinger, Abby C. King, Jenna Hua, Brian E. Saelens, Lawrence D. Frank, Terry L. Conway, Kelli L. Cain, James F. Sallis Jan 2019

How Well Do Seniors Estimate Distance To Food? The Accuracy Of Older Adults' Reported Proximity To Local Grocery Stores, Benjamin W. Chrisinger, Abby C. King, Jenna Hua, Brian E. Saelens, Lawrence D. Frank, Terry L. Conway, Kelli L. Cain, James F. Sallis

Faculty of Health Sciences Publications

(1) Background: Findings from observational studies of relations between neighborhood environments and health outcomes underscore the importance of both objective and perceived experiences of those environments. A clearer understanding of the factors associated with discrepancies between these two assessment approaches is needed to tailor public health interventions to specific populations. This study examined how individual and neighborhood characteristics affect perceptions of supermarket distance, particularly when perceptions do not match objective measures. (2) Methods: Participants were older adults (n = 880) participating in the Senior Neighborhood Quality of Life Study in the Seattle/King County, WA or Baltimore/Washington, DC regions. Two ...


Costs Of Potentially Inappropriate Medication Use In Residential Aged Care Facilities, S. L. Harrison, L. K. O'Donnell, R. Milte, S. M. Dyer, E. S. Gnanamanickam, C. Bradley, Enwu Liu, S. N. Hilmer, M. Crotty Jan 2018

Costs Of Potentially Inappropriate Medication Use In Residential Aged Care Facilities, S. L. Harrison, L. K. O'Donnell, R. Milte, S. M. Dyer, E. S. Gnanamanickam, C. Bradley, Enwu Liu, S. N. Hilmer, M. Crotty

Faculty of Health Sciences Publications

Background: The potential harms of some medications may outweigh their potential benefits (inappropriate medication use). Despite recommendations to avoid the use of potentially inappropriate medications (PIMs) in older adults, the prevalence of PIM use is high in different settings including residential aged care. However, it remains unclear what the costs of these medications are in this setting. The main objective of this study was to determine the costs of PIMs in older adults living in residential care. A secondary objective was to examine if there was a difference in costs of PIMs in a home-like model of residential care compared ...


Vertebral Fractures And Their Association With Health-Related Quality Of Life, Back Pain And Physical Function In Older Women, Lisa Johansson, Daniel Sundh, Dan Nilsson, Dan Mellström, Mattias Lorentzon Jan 2018

Vertebral Fractures And Their Association With Health-Related Quality Of Life, Back Pain And Physical Function In Older Women, Lisa Johansson, Daniel Sundh, Dan Nilsson, Dan Mellström, Mattias Lorentzon

Faculty of Health Sciences Publications

Summary Studies investigating prevalent vertebral fracture (VF) diagnosed using densitometry-based VF assessment (VFA) and associations with physical function, assessed by performance-based measures, are lacking. In this population-based study of 1027 older women, we found that prevalent VF, identified by VFA, was associated with inferior physical health, back pain and inferior physical function. Purpose: Several studies have investigated the associations between health-related quality of life (HRQL) and back pain with prevalent VF, detected by spine radiographs, but just a few have been population-based and have used vertebral fracture assessment (VFA) for diagnosing VF. The aims of this study were to investigate ...


Dynamic Balance Control During Stair Negotiation For Older Adults And People With Parkinson Disease [Accepted Manuscript], Zachary J. Conway, Tim Blackmore, Peter A. Silburn, Michael H. Cole Jan 2018

Dynamic Balance Control During Stair Negotiation For Older Adults And People With Parkinson Disease [Accepted Manuscript], Zachary J. Conway, Tim Blackmore, Peter A. Silburn, Michael H. Cole

Faculty of Health Sciences Publications

It is well understood that stability during ambulation is reliant upon appropriate control of the trunk segment, but research shows that the rhythmicity of this segment is significantly reduced for people with Parkinson’s disease (PD). Given the increased risk associated with stair ambulation, this study investigated whether people with PD demonstrate poorer trunk control during stair ambulation compared with age-matched controls. Trunk accelerations were recorded for twelve PD patients and age-matched controls during stair ascent and descent. Accelerations were used to derive measures of harmonic ratios and root mean square (RMS) acceleration to provide insight into the rhythmicity and ...


The Prevalence, Reporting, And Treatment Of Anxiety Among Older Adults In Nursing Homes And Other Residential Aged Care Facilities [Accepted Manuscript], Alexandra S. Creighton, Tanya E. Davison, David W. Kissane Jan 2018

The Prevalence, Reporting, And Treatment Of Anxiety Among Older Adults In Nursing Homes And Other Residential Aged Care Facilities [Accepted Manuscript], Alexandra S. Creighton, Tanya E. Davison, David W. Kissane

Faculty of Health Sciences Publications

Background: Little is known about anxiety in aged care populations, despite its increase in this frail population. This study investigated the prevalence, recording, and treatment rate of anxiety disorders among aged care residents. Methods: A cross-sectional, observational design was used to assess 180 elderly residents from 12 aged care facilities in Melbourne, Australia. Participants were assessed for threshold and subthreshold anxiety disorders and comorbid depression using the MINI for DSM-5. Medical files were also reviewed to determine whether there was any indication that anxiety had previously been detected, and what treatment those with a threshold/ subthreshold diagnosis were receiving. Results ...


The Spectrum Of Neurological And White Matter Changes And Premutation Status Categories Of Older Male Carriers Of The Fmr1 Alleles Are Linked To Genetic (Cgg And Fmr1 Mrna) And Cellular Stress (Ampk) Markers, Danuta Z. Loesch, Nicholas Trost, Minh Q. Bui, Eleanor Hammersley, Sui T. Lay, Sarah J. Annesley, Oana Sanislav, Claire Y. Allan, Flora Tassone, Zhi-Ping Chen, Kevin R. W. Ngoei, Bruce E. Kemp, David Francis, Paul R. Fisher, Elsdon Storey Jan 2018

The Spectrum Of Neurological And White Matter Changes And Premutation Status Categories Of Older Male Carriers Of The Fmr1 Alleles Are Linked To Genetic (Cgg And Fmr1 Mrna) And Cellular Stress (Ampk) Markers, Danuta Z. Loesch, Nicholas Trost, Minh Q. Bui, Eleanor Hammersley, Sui T. Lay, Sarah J. Annesley, Oana Sanislav, Claire Y. Allan, Flora Tassone, Zhi-Ping Chen, Kevin R. W. Ngoei, Bruce E. Kemp, David Francis, Paul R. Fisher, Elsdon Storey

Faculty of Health Sciences Publications

The fragile X premutation (PM) allele contains a CGG expansion of 55–200 repeats in the FMR1 gene’s promoter. Male PM carriers have an elevated risk of developing neurological and psychiatric changes, including an approximately 50% risk of the fragile X-associated tremor/ataxia syndrome (FXTAS). The aim of this study was to assess the relationships of regional white matter hyperintensities (wmhs) semi-quantitative scores, clinical status, motor (UPDRS, ICARS, Tremor) scales, and cognitive impairments, with FMR1-specific genetic changes, in a sample of 32 unselected male PM carriers aged 39–81 years. Half of these individuals were affected with FXTAS, while ...


Diagnosis Of Dementia In Residential Aged Care Settings In Australia: An Opportunity For Improvements In Quality Of Care?, Suzanne M. Dyer, Emmanuel S. Gnanamanickam, Enwu Liu, Craig Whitehead, Maria Crotty Jan 2018

Diagnosis Of Dementia In Residential Aged Care Settings In Australia: An Opportunity For Improvements In Quality Of Care?, Suzanne M. Dyer, Emmanuel S. Gnanamanickam, Enwu Liu, Craig Whitehead, Maria Crotty

Faculty of Health Sciences Publications

Objective: To examine the cognitive status of Australians living in residential aged care facilities (RACFs) and whether or not a dementia diagnosis was recorded. Methods: Cross‐sectional study of 541 residents of 17 RACFs spanning four states. Examination of cognitive status by Psychogeriatric Assessment Scale Cognitive Impairment Scale (PAS‐Cog) and dementia diagnosis from medical records. Results: The study population included 65% of residents with a diagnosis of dementia recorded, and 83% had a PAS‐Cog score of four or more indicating likely cognitive impairment. More than 20% of participants had likely cognitive impairment (PAS‐Cog ≥4), but no diagnosis ...


Direct Health And Residential Care Costs Of People Living With Dementia In Australian Residential Aged Care, Emmanuel S. Gnanamanickam, Suzanne M. Dyer, Rachel Milte, Stephanie L. Harrison, Enwu Liu, Tiffany Easton, Clare Bradley, Rebecca Bilton, Wendy Shulver, Julie Ratcliffe, Craig Whitehead, Maria Crotty Jan 2018

Direct Health And Residential Care Costs Of People Living With Dementia In Australian Residential Aged Care, Emmanuel S. Gnanamanickam, Suzanne M. Dyer, Rachel Milte, Stephanie L. Harrison, Enwu Liu, Tiffany Easton, Clare Bradley, Rebecca Bilton, Wendy Shulver, Julie Ratcliffe, Craig Whitehead, Maria Crotty

Faculty of Health Sciences Publications

Objectives: This analysis estimates the whole‐of‐system direct costs for people living with dementia in residential care by using a broad health and social care provision perspective and compares it to people without dementia living in residential care. Methods: Data were collected from 541 individuals living permanently in 17 care facilities across Australia. The annual cost of health and residential care was determined by using individual resource use data and reported by the dementia status of the individuals. Results: The average annual whole‐of‐system cost for people living with dementia in residential care was approximately AU$88 000 ...


Can A Single Session Of Motor Imagery Promote Motor Learning Of Locomotion In Older Adults? A Randomized Controlled Trial, Vaughan P. Nicholson, Justin W. L. Keogh, Nancy L. Low Choy Jan 2018

Can A Single Session Of Motor Imagery Promote Motor Learning Of Locomotion In Older Adults? A Randomized Controlled Trial, Vaughan P. Nicholson, Justin W. L. Keogh, Nancy L. Low Choy

Faculty of Health Sciences Publications

Purpose: To investigate the influence of a single session of locomotor-based motor imagery training on motor learning and physical performance. Patients and methods: Thirty independent adults aged > 65 years took part in the randomized controlled trial. The study was conducted within an exercise science laboratory. Participants were randomly divided into three groups following baseline locomotor testing: motor imagery training, physical training, and control groups. The motor imagery training group completed 20 imagined repetitions of a locomotor task, the physical training group completed 20 physical repetitions of a locomotor task, and the control group spent 25 minutes playing mentally stimulating games ...


How Experience Modulates Semantic Memory For Food: Evidence From Elderly Adults And Centenarians, Miriam Vignando, Marilena Aiello, Francesco Foroni, Gabriella Marcon, Mauro Tettamanti, Raffaella I. Rumiati Jan 2018

How Experience Modulates Semantic Memory For Food: Evidence From Elderly Adults And Centenarians, Miriam Vignando, Marilena Aiello, Francesco Foroni, Gabriella Marcon, Mauro Tettamanti, Raffaella I. Rumiati

Faculty of Health Sciences Publications

In order to make sense of the objects we encounter in everyday life we largely rely on previous knowledge stored in our semantic memory. Semantic memory is considered dependent on lifelong experience and cultural knowledge. So far, a few studies have investigated the role of expertise on the organization of semantic memory, whereas life-long experience has largely been overlooked. In this study, we investigated this issue using food concepts. In particular, we administered different semantic tasks using food (natural and transformed) and non-food (living and non-living things) as stimuli to participants belonging to three different age cohorts (56–74, 75 ...


Pain Education For Clinicians In Geriatrics: A Study Into Changes In Clinician Attitudes And Beliefs, Audrey P. Wang, Georgia Fisher, Jillian Hall Jan 2018

Pain Education For Clinicians In Geriatrics: A Study Into Changes In Clinician Attitudes And Beliefs, Audrey P. Wang, Georgia Fisher, Jillian Hall

Faculty of Health Sciences Publications

A lack of recognition of chronic pain in older adults has fundamental healthcare implications. A practice gap exists that affects evidence-based practice for chronic pain assessment and management specific to older adults. Psychologically informed practice (PIP) has been proposed as a method of enabling health professionals to deliver biopsychosocial pain assessment and management in their practice. The aim of this study was to test the feasibility of a single one-day structured educational program to both introduce the concept of PIP and to shift the attitudes, beliefs and orientation towards patients of clinicians working in the geriatric rehabilitation setting. An observational ...


Clustered Domestic Model Of Residential Care Is Associated With Better Consumer Rated Quality Of Care, Emmanuel S. Gnanamanickam, Suzanne M. Dyer, Rachel Milte, Enwu Liu, Julie Ratcliffe, Maria Crotty Jan 2018

Clustered Domestic Model Of Residential Care Is Associated With Better Consumer Rated Quality Of Care, Emmanuel S. Gnanamanickam, Suzanne M. Dyer, Rachel Milte, Enwu Liu, Julie Ratcliffe, Maria Crotty

Faculty of Health Sciences Publications

Objective: To compare consumer rated quality of care among individuals living long-term in homelike clustered domestic and standard models of residential care in Australia. Design: Cross-sectional study. Setting: Seventeen residential aged care facilities in four Australian states providing alternative models of care. Study participants: A sample of individuals with high prevalence of cognitive impairment living in residential care for 12 months or longer, not immediately in palliative care and having a proxy available to provide consent and assist with data collection. Of 901 eligible participants, 541 consented and participated in the study. Main outcome measure: Consumer rated quality of care ...


Lactobacillus Reuteri Reduces Bone Loss In Older Women With Low Bone Mineral Density: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial, A. G. Nilsson, D. Sundh, F. Bäckhed, Mattias Lorentzon Jan 2018

Lactobacillus Reuteri Reduces Bone Loss In Older Women With Low Bone Mineral Density: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial, A. G. Nilsson, D. Sundh, F. Bäckhed, Mattias Lorentzon

Faculty of Health Sciences Publications

Background: The importance of the gut microbiome for bone metabolism in mice has recently been demonstrated, but no studies are available in humans. Lactobacillus reuteri ATCCPTA 6475 (L. reuteri 6475) has been reported to increase bone mineral density (BMD) in mice but its effect on the human skeleton is unknown. The objective of this trial was to investigate if L. reuteri 6475 affects bone loss in older women with low BMD. Methods: In this double‐blind, placebo‐controlled study, women from the population who were 75 to 80 years old and had low BMD were randomized to orally receive 1010 ...


Reliability And Validity Of A Mediterranean Diet And Culinary Index (Medicul) Tool In An Older Population With Mild Cognitive Impairment, Sue Radd-Vagenas, Maria A. Fiatarone Singh, Michael Inskip, Yorgi Mavros, Nicola J. Gates, Guy C. Wilson, Nidhi Jain, Jacinda Meiklejohn, Henry Brodaty, Wei Wen, Nalin Singh, Bernhard T. Baune, Chao Suo, Michael K. Baker, Nasim Foroughi, Peminder S. Sachdev, Michael Valenzuela, Victoria M. Flood Jan 2018

Reliability And Validity Of A Mediterranean Diet And Culinary Index (Medicul) Tool In An Older Population With Mild Cognitive Impairment, Sue Radd-Vagenas, Maria A. Fiatarone Singh, Michael Inskip, Yorgi Mavros, Nicola J. Gates, Guy C. Wilson, Nidhi Jain, Jacinda Meiklejohn, Henry Brodaty, Wei Wen, Nalin Singh, Bernhard T. Baune, Chao Suo, Michael K. Baker, Nasim Foroughi, Peminder S. Sachdev, Michael Valenzuela, Victoria M. Flood

Faculty of Health Sciences Publications

Dementia is a leading cause of morbidity and mortality without pharmacologic prevention or cure. Mounting evidence suggests that adherence to a Mediterranean dietary pattern may slow cognitive decline, and is important to characterise in at-risk cohorts. Thus, we determined the reliability and validity of the Mediterranean Diet and Culinary Index (MediCul), a new tool, among community-dwelling individuals with mild cognitive impairment (MCI). A total of sixty-eight participants (66 % female) aged 75·9 (sd 6·6) years, from the Study of Mental and Resistance Training study MCI cohort, completed the fifty-item MediCul at two time points, followed by a 3-d food ...


Dairy Food Supplementation May Reduce Malnutrition Risk In Institutionalised Elderly, Sandra Iuliano, Shirley Poon, Xiaofang Wang, Minh Bui, Ego Seeman Jan 2017

Dairy Food Supplementation May Reduce Malnutrition Risk In Institutionalised Elderly, Sandra Iuliano, Shirley Poon, Xiaofang Wang, Minh Bui, Ego Seeman

Faculty of Health Sciences Publications

Malnutrition in institutionalised elderly increases morbidity and care costs. Meat and dairy foods are high-quality protein sources so adequate intakes may reduce malnutrition risk. We aimed to determine whether inadequate intakes of meat and dairy foods contribute to malnutrition in institutionalised elderly. This cross-sectional study involved 215 elderly residents (70·2 % females, mean age 85·8 years) from twenty-one aged-care facilities in Melbourne, Australia. Dietary intake was assessed using observed plate waste. Food groups and serving sizes were based on the Australian Guide to Healthy Eating. Nutrient content was analysed using a computerised nutrient analysis software (Xyris). Malnutrition risk was ...


Increased Cortical Porosity In Women With Hip Fracture, Daniel Sundh, A. G. Nilsson, Martin Nilsson, L. Johansson, Dan Mellström, Mattias Lorentzon Jan 2017

Increased Cortical Porosity In Women With Hip Fracture, Daniel Sundh, A. G. Nilsson, Martin Nilsson, L. Johansson, Dan Mellström, Mattias Lorentzon

Faculty of Health Sciences Publications

Background: Hip fractures cause increased mortality and disability and consume enormous healthcare resources. Only 46% of hip fracture patients have osteoporosis at the total hip according to dual‐energy X‐ray absorptiometry (DXA) measurement. Cortical porosity increases with ageing and is believed to be important for bone strength. Objective: To investigate whether older women with hip fracture have higher cortical porosity than controls, and if so whether this difference is independent of clinical risk factors and areal bone mineral density (aBMD). Methods: From an ongoing population‐based study, we identified 46 women with a prevalent X‐ray‐verified hip fracture ...


Diversity In Fall Characteristics Hampers Effective Prevention: The Precipitants, The Environment, The Fall And The Injury, Kerrie Sanders, Karen Lim, Amanda L. Stuart, Ashley Macleod, David Scott, Geoff Nicholson, Lucy Busija Jan 2017

Diversity In Fall Characteristics Hampers Effective Prevention: The Precipitants, The Environment, The Fall And The Injury, Kerrie Sanders, Karen Lim, Amanda L. Stuart, Ashley Macleod, David Scott, Geoff Nicholson, Lucy Busija

Faculty of Health Sciences Publications

Summary Falls among the elderly are common and characteristics may differ between injurious and non-injurious falls. Among 887 older Australian women followed for 1.6 years, 32% fell annually. Only 8.5% resulted in fracture and/or hospital admission. The characteristics of those falls are indistinguishable from those not coming to medical attention. Introduction The precipitants and environment of all falls occurring among a large cohort of older Caucasian women were categorised by injury status to determine if the characteristics differed between injurious and non-injurious falls. Methods Among 887 Australian women (70+ years), falls were ascertained using monthly postcard calendars ...


Association Of Cardiovascular System Medications With Cognitive Function And Dementia In Older Adults Living In Nursing Homes In Australia, Enwu Liu, Suzanne M. Dyer, Lisa Kouladjian O'Donnell, Rachel Milte, Clare E. Bradley, Stephanie L. Harrison, Emmanuel S. Gnanamanickam, Craig Whitehead, Maria Crotty Jan 2017

Association Of Cardiovascular System Medications With Cognitive Function And Dementia In Older Adults Living In Nursing Homes In Australia, Enwu Liu, Suzanne M. Dyer, Lisa Kouladjian O'Donnell, Rachel Milte, Clare E. Bradley, Stephanie L. Harrison, Emmanuel S. Gnanamanickam, Craig Whitehead, Maria Crotty

Faculty of Health Sciences Publications

OBJECTIVE:
To examine associations between cardiovascular system medication use with cognition function and diagnosis of dementia in older adults living in nursing homes in Australia.
METHODS:
As part of a cross-sectional study of 17 Australian nursing homes examining quality of life and resource use, we examined the association between cognitive impairment and cardiovascular medication use (identified using the Anatomical Therapeutic Classification System) using general linear regression and logistic regression models. People who were receiving end of life care were excluded.
RESULTS:
Participants included 541 residents with a mean age of 85.5 years (± 8.5), a mean Psychogeriatric Assessment Scale-Cognitive ...


Sedentary Time In Older Men And Women: An International Consensus Statement And Research Priorities, Shilpa Dogra, Maureen C. Ashe, Stuart J. H. Biddle, Wendy J. Brown, Mathew P. Buman, Sebastien Chastin, Paul A. Gardiner, Shigeru Inoue, Barbara J. Jefferis, Koichiro Oka, Neville Owen, Luis B. Sardinha, Dawn A. Skelton, Takemi Sugiyama, Jennifer L. Copeland Jan 2017

Sedentary Time In Older Men And Women: An International Consensus Statement And Research Priorities, Shilpa Dogra, Maureen C. Ashe, Stuart J. H. Biddle, Wendy J. Brown, Mathew P. Buman, Sebastien Chastin, Paul A. Gardiner, Shigeru Inoue, Barbara J. Jefferis, Koichiro Oka, Neville Owen, Luis B. Sardinha, Dawn A. Skelton, Takemi Sugiyama, Jennifer L. Copeland

Faculty of Health Sciences Publications

Sedentary time is a modifiable determinant of poor health, and in older adults, reducing sedentary time may be an important first step in adopting and maintaining a more active lifestyle. The primary purpose of this consensus statement is to provide an integrated perspective on current knowledge and expert opinion pertaining to sedentary behaviour in older adults on the topics of measurement, associations with health outcomes, and interventions. A secondary yet equally important purpose is to suggest priorities for future research and knowledge translation based on gaps identified. A five-step Delphi consensus process was used. Experts in the area of sedentary ...


Low Serum Dheas Predicts Increased Fracture Risk In Older Men: The Mros Sweden Study, Claes Ohlsson, Maria Nethander, Andreas Kindmark, Östen Ljunggren, Mattias Lorentzon, Björn E. Rosengren, Magnus K. Karlsson, Dan Mellström, Liesbeth Vandenput Jan 2017

Low Serum Dheas Predicts Increased Fracture Risk In Older Men: The Mros Sweden Study, Claes Ohlsson, Maria Nethander, Andreas Kindmark, Östen Ljunggren, Mattias Lorentzon, Björn E. Rosengren, Magnus K. Karlsson, Dan Mellström, Liesbeth Vandenput

Faculty of Health Sciences Publications

The adrenal‐derived hormones dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are the most abundant circulating hormones and their levels decline substantially with age. DHEAS is considered an inactive precursor, which is converted into androgens and estrogens via local metabolism in peripheral target tissues. The predictive value of serum DHEAS for fracture risk is unknown. The aim of this study was, therefore, to assess the associations between baseline DHEAS levels and incident fractures in a large cohort of older men. Serum DHEAS levels were analyzed with mass spectrometry in the population‐based Osteoporotic Fractures in Men study in Sweden (n = 2568 ...


Low Testosterone, But Not Estradiol, Is Associated With Incident Falls In Older Men: The International Mros Study, Liesbeth Vandenput, Dan Mellström, Gail A. Laughlin, Peggy M. Cawthon, Jane A. Cauley, Andrew R. Hoffman, Magnus K. Karlsson, Björn E. Rosengren, Östen Ljunggren, Maria Nethander, Anna L. Eriksson, Mattias Lorentzon, Jason Leung, Timothy Kwok, Eric S. Orwoll, Claes Ohlsson Jan 2017

Low Testosterone, But Not Estradiol, Is Associated With Incident Falls In Older Men: The International Mros Study, Liesbeth Vandenput, Dan Mellström, Gail A. Laughlin, Peggy M. Cawthon, Jane A. Cauley, Andrew R. Hoffman, Magnus K. Karlsson, Björn E. Rosengren, Östen Ljunggren, Maria Nethander, Anna L. Eriksson, Mattias Lorentzon, Jason Leung, Timothy Kwok, Eric S. Orwoll, Claes Ohlsson

Faculty of Health Sciences Publications

Fracture risk is determined by bone strength and the risk of falls. The relationship between serum sex steroids and bone strength parameters in men is well known, whereas the predictive value of sex steroids for falls is less studied. The aim of this study was to assess the associations between serum testosterone (T) and estradiol (E2) and the likelihood of falls. Older men (aged ≥65 years) from the United States (n = 1919), Sweden (n = 2495), and Hong Kong (n = 1469) participating in the Osteoporotic Fractures in Men Study had baseline T and E2 analyzed by mass spectrometry. Bioavailable (Bio) levels ...


Type 2 Diabetes And Risk Of Hip Fractures And Non-Skeletal Fall Injuries In The Elderly: A Study From The Fractures And Fall Injuries In The Elderly Cohort (Frailco), Märit Wallander, Kristian F. Axelsson, Anna G. Nilsson, Dan Lundh, Mattias Lorentzon Jan 2017

Type 2 Diabetes And Risk Of Hip Fractures And Non-Skeletal Fall Injuries In The Elderly: A Study From The Fractures And Fall Injuries In The Elderly Cohort (Frailco), Märit Wallander, Kristian F. Axelsson, Anna G. Nilsson, Dan Lundh, Mattias Lorentzon

Faculty of Health Sciences Publications

Questions remain about whether the increased risk of fractures in patients with type 2 diabetes (T2DM) is related mainly to increased risk of falling or to bone‐specific properties. The primary aim of this study was to investigate the risk of hip fractures and non‐skeletal fall injuries in older men and women with and without T2DM. We included 429,313 individuals (aged 80.8 ± 8.2 years [mean ± SD], 58% women) from the Swedish registry “Senior Alert” and linked the data to several nationwide registers. We identified 79,159 individuals with T2DM (45% with insulin [T2DM‐I], 41% with ...


Type 2 Diabetes Mellitus Is Associated With Better Bone Microarchitecture But Lower Bone Material Strength And Poorer Physical Function In Elderly Women: A Population-Based Study, Anna G. Nilsson, Daniel Sundh, Lisa Johansson, Martin Nilsson, Dan Mellström, Robert Rudäng, Michail Zoulakis, Märit Wallander, Anna Darelid, Mattias Lorentzon Jan 2017

Type 2 Diabetes Mellitus Is Associated With Better Bone Microarchitecture But Lower Bone Material Strength And Poorer Physical Function In Elderly Women: A Population-Based Study, Anna G. Nilsson, Daniel Sundh, Lisa Johansson, Martin Nilsson, Dan Mellström, Robert Rudäng, Michail Zoulakis, Märit Wallander, Anna Darelid, Mattias Lorentzon

Faculty of Health Sciences Publications

Type 2 diabetes mellitus (T2DM) is associated with an increased risk of fractures according to several studies. The underlying mechanisms remain unclear, although small case‐control studies indicate poor quality of the cortical bone. We have studied a population‐based sample of women aged 75 to 80 years in Gothenburg, randomly invited from the population register. Areal bone mineral density (aBMD) was measured by dual‐energy X‐ray absorptiometry (Hologic Discovery A), bone microarchitecture by high‐resolution peripheral quantitative computed tomography (HR‐pQCT; ExtremeCT from Scanco Medical AG), and reference point indentation was performed with Osteoprobe (Active Life Scientific). Women ...


Exploring The Journey Towards Successful Ageing In The Philippines: A Mixed Method Study, Nicamil Sanchez Dec 2016

Exploring The Journey Towards Successful Ageing In The Philippines: A Mixed Method Study, Nicamil Sanchez

Theses

Currently, there are no universally accepted definitions, dimensions or scales for measuring successful ageing. Rowe and Kahn’s (1977) three dimensions of successful ageing, namely, wellbeing, physical functioning, and social engagement, have been adopted by most studies in the literature to measure successful ageing. A review of the extant literature on successful ageing revealed that the majority of the studies on successful ageing have been conducted in developed western countries, despite the fact that the majority of older persons live in developing countries like the Philippines. Additionally, studies on successful ageing have been limited in their consideration of the sociocultural ...


Social Dancing And Incidence Of Falls In Older Adults: A Cluster Randomised Controlled Trial, Dafna Merom, Erin Mathieu, Ester Cerin, Rachael L. Morton, Judy M. Simpson, Chris Rissel, Kaarin J. Anstey, Catherine Sherrington, Stephen R. Lord, Robert G. Cumming Jan 2016

Social Dancing And Incidence Of Falls In Older Adults: A Cluster Randomised Controlled Trial, Dafna Merom, Erin Mathieu, Ester Cerin, Rachael L. Morton, Judy M. Simpson, Chris Rissel, Kaarin J. Anstey, Catherine Sherrington, Stephen R. Lord, Robert G. Cumming

Faculty of Health Sciences Publications

Background: The prevention of falls among older people is a major public health challenge. Exercises that challenge balance are recognized as an efficacious fall prevention strategy. Given that small-scale trials have indicated that diverse dance styles can improve balance and gait of older adults, two of the strongest risk factors for falls in older people, this study aimed to determine whether social dance is effective in i) reducing the number of falls and ii) improving physical and cognitive fall-related risk factors. Methods and Findings: A parallel two-arm cluster randomized controlled trial was undertaken in 23 self-care retirement villages (clusters) around ...


Low Serum Vitamin D Is Associated With Higher Cortical Porosity In Elderly Men, D. Sundh, Dan Mellström, Östen Ljunggren, Magnus K. Karlsson, Claes Ohlsson, M. Nilsson, A. G. Nilsson, Mattias Lorentzon Jan 2016

Low Serum Vitamin D Is Associated With Higher Cortical Porosity In Elderly Men, D. Sundh, Dan Mellström, Östen Ljunggren, Magnus K. Karlsson, Claes Ohlsson, M. Nilsson, A. G. Nilsson, Mattias Lorentzon

Faculty of Health Sciences Publications

Background: Bone loss at peripheral sites in the elderly is mainly cortical and involves increased cortical porosity. However, an association between bone loss at these sites and 25‐hydroxyvitamin D has not been reported. Objective: To investigate the association between serum levels of 25‐hydroxyvitamin D, bone microstructure and areal bone mineral density (BMD) in elderly men. Methods: A population‐based cohort of 444 elderly men (mean ± SD age 80.2 ± 3.5 years) was investigated. Bone microstructure was measured by high‐resolution peripheral quantitative computed tomography, areal BMD by dual‐energy X‐ray absorptiometry and serum 25‐hydroxyvitamin D ...


Trialling Of An Optimal Health Programme (Ohp) Across Chronic Disease, Chantal Ski, David Thompson, David J. Castle Jan 2016

Trialling Of An Optimal Health Programme (Ohp) Across Chronic Disease, Chantal Ski, David Thompson, David J. Castle

Faculty of Health Sciences Publications

Population ageing is a worldwide phenomenon, most advanced in developed countries and expected to continue over the next few decades. As people are surviving longer with age-associated disease and disability, there is an imperative to identify innovative solutions for an already overburdened health care system. Such innovations need to be focused on disease management, taking into consideration the strong associations that have been established between psychosocial factors and pathophysiological mechanisms associated with chronic disease. Aside from personal and community costs, chronic diseases produce a significant economic burden due to the culmination of health care costs and lost productivity. This commentary ...