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Articles 1 - 30 of 939
Full-Text Articles in Medicine and Health Sciences
High-Resolution Physical Map For Chromosome 16q12.1-Q13, The Blau Syndrome Locus., Xiaoju Wang, Helena Kuivaniemi, Gina Bonavita, Charlene J Williams, Gerard Tromp
High-Resolution Physical Map For Chromosome 16q12.1-Q13, The Blau Syndrome Locus., Xiaoju Wang, Helena Kuivaniemi, Gina Bonavita, Charlene J Williams, Gerard Tromp
Charlene Williams
BACKGROUND: The Blau syndrome (MIM 186580), an autosomal dominant granulomatous disease, was previously mapped to chromosome 16p12-q21. However, inconsistent physical maps of the region and consequently an unknown order of microsatellite markers, hampered us from further refining the genetic locus for the Blau syndrome. To address this problem, we constructed our own high-resolution physical map for the Blau susceptibility region. RESULTS: We generated a high-resolution physical map that provides more than 90% coverage of a refined Blau susceptibility region. The map consists of four contigs of sequence tagged site-based bacterial artificial chromosomes with a total of 124 bacterial artificial chromosomes, …
P5l Mutation In Ank Results In An Increase In Extracellular Inorganic Pyrophosphate During Proliferation And Nonmineralizing Hypertrophy In Stably Transduced Atdc5 Cells, Raihana Zaka, David Stokes, Arnold S. Dion, Anna Kusnierz, Fei Han, Charlene J. Williams
P5l Mutation In Ank Results In An Increase In Extracellular Inorganic Pyrophosphate During Proliferation And Nonmineralizing Hypertrophy In Stably Transduced Atdc5 Cells, Raihana Zaka, David Stokes, Arnold S. Dion, Anna Kusnierz, Fei Han, Charlene J. Williams
Charlene Williams
Ank is a multipass transmembrane protein that regulates the cellular transport of inorganic pyrophosphate. In the progressive ankylosis (ank) mouse, a premature termination mutation at glutamic acid 440 results in a phenotype characterized by inappropriate deposition of basic calcium phosphate crystals in skeletal tissues. Mutations in the amino terminus of ANKH, the human homolog of Ank, result in familial calcium pyrophosphate dihydrate deposition disease. It has been hypothesized that these mutations result in a gain-of-function with respect to the elaboration of extracellular inorganic pyrophosphate. To explore this issue in a mineralization-competent system, we stably transduced ATDC5 cells with wild-type Ank …
Epilepsy, Hippocampal Sclerosis And Febrile Seizures Linked By Common Genetic Variation Around Scn1a., Dalia Kasperaviciute, Claudia B Catarino, Mar Matarin, Costin Leu, Jan Novy, Anna Tostevin, Bárbara Leal, Ellen V S Hessel, Kerstin Hallmann, Michael S Hildebrand, Hans-Henrik M Dahl, Mina Ryten, Daniah Trabzuni, Adaikalavan Ramasamy, Saud Alhusaini, Colin P Doherty, Thomas Dorn, Jörg Hansen, Günter Krämer, Bernhard J Steinhoff, Dominik Zumsteg, Susan Duncan, Reetta K Kälviäinen, Kai J Eriksson, Anne-Mari Kantanen, Massimo Pandolfo, Ursula Gruber-Sedlmayr, Kurt Schlachter, Eva M Reinthaler, Elisabeth Stogmann, Fritz Zimprich, Emilie Théâtre, Colin Smith, Terence J O'Brien, K Meng Tan, Slave Petrovski, Angela Robbiano, Roberta Paravidino, Federico Zara, Pasquale Striano, Michael R Sperling, Russell J Buono, Hakon Hakonarson, João Chaves, Paulo P Costa, Berta M Silva, António M Da Silva, Pierre N E De Graan, Bobby P C Koeleman, Albert Becker, Susanne Schoch, Marec Von Lehe, Philipp S Reif, Felix Rosenow, Felicitas Becker, Yvonne Weber, Holger Lerche, Karl Rössler, Michael Buchfelder, Hajo M Hamer, Katja Kobow, Roland Coras, Ingmar Blumcke, Ingrid E Scheffer, Samuel F Berkovic, Michael E. Weale, Uk Brain Expression Consortium, Norman Delanty, Chantal Depondt, Gianpiero L Cavalleri, Wolfram S Kunz, Sanjay M Sisodiya
Epilepsy, Hippocampal Sclerosis And Febrile Seizures Linked By Common Genetic Variation Around Scn1a., Dalia Kasperaviciute, Claudia B Catarino, Mar Matarin, Costin Leu, Jan Novy, Anna Tostevin, Bárbara Leal, Ellen V S Hessel, Kerstin Hallmann, Michael S Hildebrand, Hans-Henrik M Dahl, Mina Ryten, Daniah Trabzuni, Adaikalavan Ramasamy, Saud Alhusaini, Colin P Doherty, Thomas Dorn, Jörg Hansen, Günter Krämer, Bernhard J Steinhoff, Dominik Zumsteg, Susan Duncan, Reetta K Kälviäinen, Kai J Eriksson, Anne-Mari Kantanen, Massimo Pandolfo, Ursula Gruber-Sedlmayr, Kurt Schlachter, Eva M Reinthaler, Elisabeth Stogmann, Fritz Zimprich, Emilie Théâtre, Colin Smith, Terence J O'Brien, K Meng Tan, Slave Petrovski, Angela Robbiano, Roberta Paravidino, Federico Zara, Pasquale Striano, Michael R Sperling, Russell J Buono, Hakon Hakonarson, João Chaves, Paulo P Costa, Berta M Silva, António M Da Silva, Pierre N E De Graan, Bobby P C Koeleman, Albert Becker, Susanne Schoch, Marec Von Lehe, Philipp S Reif, Felix Rosenow, Felicitas Becker, Yvonne Weber, Holger Lerche, Karl Rössler, Michael Buchfelder, Hajo M Hamer, Katja Kobow, Roland Coras, Ingmar Blumcke, Ingrid E Scheffer, Samuel F Berkovic, Michael E. Weale, Uk Brain Expression Consortium, Norman Delanty, Chantal Depondt, Gianpiero L Cavalleri, Wolfram S Kunz, Sanjay M Sisodiya
Russell Buono
Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and mesial temporal lobe epilepsy with hippocampal sclerosis is frequently associated with important co-morbidities, mandating the search for better understanding and treatment. The cause of mesial temporal lobe epilepsy with hippocampal sclerosis is unknown, but there is an association with childhood febrile seizures. Several rarer epilepsies featuring febrile seizures are caused by mutations in SCN1A, which encodes a brain-expressed sodium channel subunit targeted by many anti-epileptic drugs. We undertook a genome-wide association …
Ten-Year (2001-2011) Trends In The Incidence Rates And Short-Term Outcomes Of Early Versus Late Onset Cardiogenic Shock After Hospitalization For Acute Myocardial Infarction, Hoa L. Nguyen, Jorge L. Yarzebski, Darleen M. Lessard, Joel M. Gore, David D. Mcmanus, Robert J. Goldberg
Ten-Year (2001-2011) Trends In The Incidence Rates And Short-Term Outcomes Of Early Versus Late Onset Cardiogenic Shock After Hospitalization For Acute Myocardial Infarction, Hoa L. Nguyen, Jorge L. Yarzebski, Darleen M. Lessard, Joel M. Gore, David D. Mcmanus, Robert J. Goldberg
Jorge L. Yarzebski
BACKGROUND: Cardiogenic shock (CS) is a serious complication of acute myocardial infarction, and the time of onset of CS has a potential role in influencing its prognosis. Limited contemporary data exist on this complication, however, especially from a population-based perspective. Our study objectives were to describe decade-long trends in the incidence, in-hospital mortality, and factors associated with the development of CS in 3 temporal contexts: (1) before hospital arrival for acute myocardial infarction (prehospital CS); (2) within 24 hours of hospitalization (early CS); and (3) > /=24 hours after hospitalization (late CS). METHODS AND RESULTS: The study population consisted of 5782 …
Survival Advantage Of Both Human Hepatocyte Xenografts And Genome-Edited Hepatocytes For Treatment Of Alpha-1 Antitrypsin Deficiency, Florie Borel, Qiushi Tang, Gwladys Gernoux, Cynthia Greer, Ziqiong Wang, Adi Barzel, Mark A. Kay, Leonard D. Shultz, Dale L. Greiner, Terence R. Flotte, Michael A. Brehm, Christian Mueller
Survival Advantage Of Both Human Hepatocyte Xenografts And Genome-Edited Hepatocytes For Treatment Of Alpha-1 Antitrypsin Deficiency, Florie Borel, Qiushi Tang, Gwladys Gernoux, Cynthia Greer, Ziqiong Wang, Adi Barzel, Mark A. Kay, Leonard D. Shultz, Dale L. Greiner, Terence R. Flotte, Michael A. Brehm, Christian Mueller
Christian Mueller
Hepatocytes represent an important target for gene therapy and editing of single-gene disorders. In alpha-1 antitrypsin (AAT) deficiency, one missense mutation results in impaired secretion of AAT. In most patients, lung damage occurs due to a lack of AAT-mediated protection of lung elastin from neutrophil elastase. In some patients, accumulation of misfolded PiZ mutant AAT protein triggers hepatocyte injury, leading to inflammation and cirrhosis. We hypothesized that correcting the Z mutant defect in hepatocytes would confer a selective advantage for repopulation of hepatocytes within an intact liver. A human PiZ allele was crossed onto an immune-deficient (NSG) strain to create …
Using Creative Art To Explore Psychoanalytic Process, Robert Irwin Wolf
Using Creative Art To Explore Psychoanalytic Process, Robert Irwin Wolf
Robert Irwin Wolf
No abstract provided.
Niemann-Pick Type C Disease, Sameh Morkous Md, Faan
Niemann-Pick Type C Disease, Sameh Morkous Md, Faan
Sameh Morkous, MD, FAAP, FAAN
No abstract provided.
Gallic Acid, A Phenolic Compound, Exerts Anti-Angiogenic Effects Via The Pten/Akt/Hif-1Α/Vegf Signaling Pathway In Ovarian Cancer Cells, Zhiping He, Allen Y. Chen, Yon Rojanasakul, Gary O. Rankin, Yi Charlie Chen
Gallic Acid, A Phenolic Compound, Exerts Anti-Angiogenic Effects Via The Pten/Akt/Hif-1Α/Vegf Signaling Pathway In Ovarian Cancer Cells, Zhiping He, Allen Y. Chen, Yon Rojanasakul, Gary O. Rankin, Yi Charlie Chen
Gary O. Rankin
Gallic acid (GA), a polyphenol, is widely found in numerous fruits and vegetables, particularly in hickory nuts. In the present study, we found that gallic acid, a natural phenolic compound isolated from fruits and vegetables, had a more potent growth inhibitory effect on two ovarian cancer cell lines, OVCAR-3 and A2780/CP70, than the effect on a normal ovarian cell line, IOSE-364. These results demonstrated that GA selectively inhibits the growth of cancer cells. Gene expression was examined by ELISA and western blot analysis, and gene pathways were examined by luciferase assay. It was found that GA inhibited VEGF secretion and …
Myricetin Inhibits Proliferation Of Cisplatin-Resistant Cancer Cells Through A P53-Dependent Apoptotic Pathway, Haizhi Huang, Allen Y. Chen, Xingqian Ye, Bingyun Li, Yon Rojanasakul, Gary O. Rankin, Yi Charlie Chen
Myricetin Inhibits Proliferation Of Cisplatin-Resistant Cancer Cells Through A P53-Dependent Apoptotic Pathway, Haizhi Huang, Allen Y. Chen, Xingqian Ye, Bingyun Li, Yon Rojanasakul, Gary O. Rankin, Yi Charlie Chen
Gary O. Rankin
Cisplatin is a commonly used drug for cancer treatment by crosslinking DNA, leading to apoptosis of cancer cells, resistance to cisplatin treatment often occurs, leading to relapse. Therefore, there is a need for the development of more effective treatment strategies that can overcome chemoresistance. Myricetin is a flavonoid from fruits and vegetables, showing anticancer activity in various cancer cells. In this study, we found myricetin exhibited greater cytotoxicity than cisplatin in two cisplatin-resistant ovarian cancer cell lines, OVCAR-3 and A2780/CP70, and it was less cytotoxic to the normal ovarian cell line IOSE-364. Myricetin selectively induced apoptosis in both cisplatin-resistant cancer …
Cerium Oxide Nanoparticle Treatment Ameliorates Peritonitis-Induced Diaphragm Dysfunction, Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, Bing Ma, Kevin M. Rice, Vellaisamy Selvaraj, Eric Blough
Cerium Oxide Nanoparticle Treatment Ameliorates Peritonitis-Induced Diaphragm Dysfunction, Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, Bing Ma, Kevin M. Rice, Vellaisamy Selvaraj, Eric Blough
Nandini Manne
The severe inflammation observed during sepsis is thought to cause diaphragm dysfunction, which is associated with poor patient prognosis. Cerium oxide (CeO2) nanoparticles have been posited to exhibit anti-inflammatory and antioxidative activities suggesting that these particles may be of potential use for the treatment of inflammatory disorders. To investigate this possibility, Sprague Dawley rats were randomly assigned to the following groups: sham control, CeO2 nanoparticle treatment only (0.5 mg/kg iv), sepsis, and sepsis+CeO2 nanoparticles. Sepsis was induced by the introduction of cecal material (600 mg/kg) directly into the peritoneal cavity. Nanoparticle treatment decreased sepsis-associated impairments in …
Cerium Oxide Nanoparticle Treatment Ameliorates Peritonitis-Induced Diaphragm Dysfunction, Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, Bing Ma, Kevin M. Rice, Vellaisamy Selvaraj, Eric Blough
Cerium Oxide Nanoparticle Treatment Ameliorates Peritonitis-Induced Diaphragm Dysfunction, Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, Bing Ma, Kevin M. Rice, Vellaisamy Selvaraj, Eric Blough
Kevin M Rice
The severe inflammation observed during sepsis is thought to cause diaphragm dysfunction, which is associated with poor patient prognosis. Cerium oxide (CeO2) nanoparticles have been posited to exhibit anti-inflammatory and antioxidative activities suggesting that these particles may be of potential use for the treatment of inflammatory disorders. To investigate this possibility, Sprague Dawley rats were randomly assigned to the following groups: sham control, CeO2 nanoparticle treatment only (0.5 mg/kg iv), sepsis, and sepsis+CeO2 nanoparticles. Sepsis was induced by the introduction of cecal material (600 mg/kg) directly into the peritoneal cavity. Nanoparticle treatment decreased sepsis-associated impairments in diaphragmatic contractile (Po) function …
Cerium Oxide Nanoparticle Treatment Ameliorates Peritonitis-Induced Diaphragm Dysfunction, Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, Bing Ma, Kevin M. Rice, Vellaisamy Selvaraj, Eric Blough
Cerium Oxide Nanoparticle Treatment Ameliorates Peritonitis-Induced Diaphragm Dysfunction, Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, Bing Ma, Kevin M. Rice, Vellaisamy Selvaraj, Eric Blough
Eric Blough
The severe inflammation observed during sepsis is thought to cause diaphragm dysfunction, which is associated with poor patient prognosis. Cerium oxide (CeO2) nanoparticles have been posited to exhibit anti-inflammatory and antioxidative activities suggesting that these particles may be of potential use for the treatment of inflammatory disorders. To investigate this possibility, Sprague Dawley rats were randomly assigned to the following groups: sham control, CeO2 nanoparticle treatment only (0.5 mg/kg iv), sepsis, and sepsis+CeO2 nanoparticles. Sepsis was induced by the introduction of cecal material (600 mg/kg) directly into the peritoneal cavity. Nanoparticle treatment decreased sepsis-associated impairments in …
Techniques To Improve Patient Flow In A Pediatric Street Medicine Clinic., Richelle Reinhart, Carly Crowder, Nikos Karakashian, Ajay Koti Ms, Kathleen Mcfadden, Marna R. Greenberg Do, Mph, Facep
Techniques To Improve Patient Flow In A Pediatric Street Medicine Clinic., Richelle Reinhart, Carly Crowder, Nikos Karakashian, Ajay Koti Ms, Kathleen Mcfadden, Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Teaching With Cultural Competence Requires Gender Sensitivity., Marna R. Greenberg Do, Mph, Facep, Jessica Pierog Do
Teaching With Cultural Competence Requires Gender Sensitivity., Marna R. Greenberg Do, Mph, Facep, Jessica Pierog Do
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Lack Of Gender Differences In Prevalence Of Homelessness In The Emergency Department (Poster)., Brett Feldman Mspas, Pa-C, Alexandra M. Craen Ba, Osman Z. Abbasi Do, Zachary M. Dillon Md, Kenneth Dzike Md, Joshua Enyart Do, Julie A. Fritzges Do, Jessica L. Glaubman Do, Emily A. Kiernan Do, Nathaniel M. Yoder Do, Timothy J. Friel Md, Stephen W. Dusza Drph, Marna R. Greenberg Do, Mph, Facep
Lack Of Gender Differences In Prevalence Of Homelessness In The Emergency Department (Poster)., Brett Feldman Mspas, Pa-C, Alexandra M. Craen Ba, Osman Z. Abbasi Do, Zachary M. Dillon Md, Kenneth Dzike Md, Joshua Enyart Do, Julie A. Fritzges Do, Jessica L. Glaubman Do, Emily A. Kiernan Do, Nathaniel M. Yoder Do, Timothy J. Friel Md, Stephen W. Dusza Drph, Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Vulnerable Elder Survey As A Predictor Of Falls In The Emergency Medicine Setting., Rebecca Brown Ms2, Marna R. Greenberg Do, Mph, Facep
Vulnerable Elder Survey As A Predictor Of Falls In The Emergency Medicine Setting., Rebecca Brown Ms2, Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Development Of A Health Care Systems Curriculum., Zachary Pruitt, Rahul Mhaskar, Bryan G. Kane Md, Robert D. Barraco Md, Mph, Deborah J Dewaay, Alexander M. Rosenau Do, Kristin A. Bresnan Md, Marna R. Greenberg Do, Mph, Facep
Development Of A Health Care Systems Curriculum., Zachary Pruitt, Rahul Mhaskar, Bryan G. Kane Md, Robert D. Barraco Md, Mph, Deborah J Dewaay, Alexander M. Rosenau Do, Kristin A. Bresnan Md, Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
Background: There is currently no gold standard for delivery of systems-based practice in medical education, and it is challenging to incorporate into medical education. Health systems competence requires physicians to understand patient care within the broader health care system and is vital to improving the quality of care clinicians provide. We describe a health systems curriculum that utilizes problem-based learning across 4 years of systems-based practice medical education at a single institution.
Methods: This case study describes the application of a problem-based learning approach to system-based practice medical education. A series of behavioral statements, called entrustable professional activities, was created …
Evaluating The Effectiveness Of The 30-Second Chair Stand Test As An Ed Screening Tool For Elderly Fall Risk Assessment., Adison Weseloh, Bryan G. Kane Md, Jeanne L. Jacoby Md, Robert D. Barraco Md, Mph, Tracy M Bishop Do, Kyli Krape Do, Stephanie Merrick Md, Michael Wagner, Deirdre Warner Do, Marna R. Greenberg Do, Mph, Facep
Evaluating The Effectiveness Of The 30-Second Chair Stand Test As An Ed Screening Tool For Elderly Fall Risk Assessment., Adison Weseloh, Bryan G. Kane Md, Jeanne L. Jacoby Md, Robert D. Barraco Md, Mph, Tracy M Bishop Do, Kyli Krape Do, Stephanie Merrick Md, Michael Wagner, Deirdre Warner Do, Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Identifying Demographics And Biopsychosocial Characteristics Among Emergency Youth Shelter Residents., Aleksandra Bacewicz, Elizabeth Beaty, Cristina Calogero, Carly Crowder, Ajay Koti Ms, Kathleen Mcfadden, Richelle Reinhart, Seth Vanzant, Marna R. Greenberg Do, Mph, Facep
Identifying Demographics And Biopsychosocial Characteristics Among Emergency Youth Shelter Residents., Aleksandra Bacewicz, Elizabeth Beaty, Cristina Calogero, Carly Crowder, Ajay Koti Ms, Kathleen Mcfadden, Richelle Reinhart, Seth Vanzant, Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Gender Differences In Acute Cardiac Care: Where It's Not., Marna R. Greenberg Do, Mph, Facep
Gender Differences In Acute Cardiac Care: Where It's Not., Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
Gender Differences In Cdc Guideline Compliance For Stis In Emergency Departments., Bryan G. Kane Md, Alexander W D Guillaume, Elizabeth M. Evans Do, Terrence E. Goyke Do, Jessica K. Eygnor Do, Lauren Semler Ms, Stephen W. Duza Drph, Marna R. Greenberg Do, Mph, Facep
Gender Differences In Cdc Guideline Compliance For Stis In Emergency Departments., Bryan G. Kane Md, Alexander W D Guillaume, Elizabeth M. Evans Do, Terrence E. Goyke Do, Jessica K. Eygnor Do, Lauren Semler Ms, Stephen W. Duza Drph, Marna R. Greenberg Do, Mph, Facep
Marna R Greenberg DO, MPH, FACEP
No abstract provided.
10-Year Outcome Of The Thoracic Endovascular Aortic Repair (Tevar) Procedure (Poster), Jacob Fink, Youssef Zaki, Tim S. Misselbeck Md, James K. Wu Md
10-Year Outcome Of The Thoracic Endovascular Aortic Repair (Tevar) Procedure (Poster), Jacob Fink, Youssef Zaki, Tim S. Misselbeck Md, James K. Wu Md
James K. Wu, M.D.
No abstract provided.
Comparison Of In-Line Versus Conventional Independent Continuous Renal Replacement Therapy In Extracorporeal Membrane Oxygenation Patients, Nicole Stansbury, Taryn Samet Md, Tim S. Misselbeck Md, James K. Wu Md
Comparison Of In-Line Versus Conventional Independent Continuous Renal Replacement Therapy In Extracorporeal Membrane Oxygenation Patients, Nicole Stansbury, Taryn Samet Md, Tim S. Misselbeck Md, James K. Wu Md
James K. Wu, M.D.
No abstract provided.
10-Year Outcome Of The Thoracic Endovascular Aortic Repair (Tevar) Procedure, James K. Wu Md, Tim S. Misselbeck Md, Jacob Fink, Youssef Zaki
10-Year Outcome Of The Thoracic Endovascular Aortic Repair (Tevar) Procedure, James K. Wu Md, Tim S. Misselbeck Md, Jacob Fink, Youssef Zaki
James K. Wu, M.D.
No abstract provided.
Feasability Study To Assess Addition Of A Prophylactic Antiarrhythmic Regimen To Post-Operative Open-Heart Surgery Management., Cameron St. Hilaire, Travis Gaskill Pa-C, Sarah Dolcemascolo Pa-C, James K. Wu Md
Feasability Study To Assess Addition Of A Prophylactic Antiarrhythmic Regimen To Post-Operative Open-Heart Surgery Management., Cameron St. Hilaire, Travis Gaskill Pa-C, Sarah Dolcemascolo Pa-C, James K. Wu Md
James K. Wu, M.D.
No abstract provided.
Development Of A Health Care Systems Curriculum., Zachary Pruitt, Rahul Mhaskar, Bryan G. Kane Md, Robert D. Barraco Md, Mph, Deborah J Dewaay, Alexander M. Rosenau Do, Kristin A. Bresnan Md, Marna R. Greenberg Do, Mph, Facep
Development Of A Health Care Systems Curriculum., Zachary Pruitt, Rahul Mhaskar, Bryan G. Kane Md, Robert D. Barraco Md, Mph, Deborah J Dewaay, Alexander M. Rosenau Do, Kristin A. Bresnan Md, Marna R. Greenberg Do, Mph, Facep
Bryan G Kane MD
Background: There is currently no gold standard for delivery of systems-based practice in medical education, and it is challenging to incorporate into medical education. Health systems competence requires physicians to understand patient care within the broader health care system and is vital to improving the quality of care clinicians provide. We describe a health systems curriculum that utilizes problem-based learning across 4 years of systems-based practice medical education at a single institution.
Methods: This case study describes the application of a problem-based learning approach to system-based practice medical education. A series of behavioral statements, called entrustable professional activities, was created …
Survey Instrument: Data Challenges Of Biomedical Researchers In The Age Of Omics, Rolando Garcia-Milian, Denise Hersey, Milica Vukmirovic
Survey Instrument: Data Challenges Of Biomedical Researchers In The Age Of Omics, Rolando Garcia-Milian, Denise Hersey, Milica Vukmirovic
Rolando Garcia-Milian
No abstract provided.
Interview Questionaire: Data Challenges Of Biomedical Researchers In The Age Of Omics, Rolando Garcia-Milian, Denise Hersey, Milica Vukmirovic
Interview Questionaire: Data Challenges Of Biomedical Researchers In The Age Of Omics, Rolando Garcia-Milian, Denise Hersey, Milica Vukmirovic
Rolando Garcia-Milian
No abstract provided.
Burnout Syndrome In Hospital's Nurses: Causes And Consequences, Lama Bakhamis, Harlan M. Smith Ii, Alberto Coustasse, David P. Paul Iii
Burnout Syndrome In Hospital's Nurses: Causes And Consequences, Lama Bakhamis, Harlan M. Smith Ii, Alberto Coustasse, David P. Paul Iii
Harlan M. Smith
PURPOSE: The purpose of this research was to examine the causes and consequences of Burnout Syndrome among RNs in U.S. hospitals to identify solutions to this problem.
METHODS: The methodology was the review of the literature and a semi-structured interview. There were seven primary databases and two websites used in this research, and 35 articles were used for this literature review.
RESULTS: Causes and risk factors of burnout syndrome among RNs have been categorized into four major areas: individual, management, organizational, and work characteristics. Burnout syndrome rate among RNs with age under 30 years was 43.6% higher …
Burnout Syndrome In Hospital's Nurses: Causes And Consequences, Lama Bakhamis, Harlan M. Smith Ii, Alberto Coustasse, David P. Paul Iii
Burnout Syndrome In Hospital's Nurses: Causes And Consequences, Lama Bakhamis, Harlan M. Smith Ii, Alberto Coustasse, David P. Paul Iii
Alberto Coustasse, DrPH, MD, MBA, MPH
PURPOSE: The purpose of this research was to examine the causes and consequences of Burnout Syndrome among RNs in U.S. hospitals to identify solutions to this problem. METHODS: The methodology was the review of the literature and a semi-structured interview. There were seven primary databases and two websites used in this research, and 35 articles were used for this literature review. RESULTS: Causes and risk factors of burnout syndrome among RNs have been categorized into four major areas: individual, management, organizational, and work characteristics. Burnout syndrome rate among RNs with age under 30 years was 43.6% higher than RNs over …