Medicine and Health Sciences Commons^™

The Link Between Heart Disease In Low Socioeconomic Communities In America, Khristopher Chea

Nursing | Senior Theses

As a future medical professional in the healthcare field, we continue to see patients admitted for cardiovascular issues. Cardiovascular diseases (CVDs) remain the leading cause of mortality among adults living in the U.S. despite advances in treatment throughout the past century. A number of risk factors such as hypertension, obesity, smoking, and physical inactivity contribute to the significant rise of cardiovascular disease. Research data suggests that there is correlation between cardiovascular disease, low socioeconomic status, and diet. According to the American Phycological Association socioeconomic status is measured by income, educational status, and occupation, and has been shown to be closely …

The Effects Of Moderate-Severe Plaque Psoriasis On Patient Well-Being And Prevention Of Flares, Glenn Devera

Nursing | Senior Theses

Psoriasis is a chronic skin condition that is indicated by red, patchy and scaly skin that can be painful when irritated. Patients with psoriasis have an increased risk for a number of chronic diseases. Despite the expansion of treatments for moderate-to-severe psoriasis over the last decade, patients may still find that treatment strategies are not as successful, leaving them dissatisfied with their treatments. A relationship built upon trust between the nurse and the patient diagnosed with psoriasis may serve to help ensure optimal care. A comprehensive literature review was performed and found that best practices for patient management need to …

The Youthful Pandemic, Brook Sahlemariam

Nursing | Senior Theses

This paper attempts to examine the neurological, physical, and societal effects of e-cigarette use among youth and young-adults in North America. Furthermore, the paper investigates the parallels between e-cigarette users, tobacco users, and dual users in regard to behavioral patterns, reasons for use, and age of initiation.

Gut Microbiota And The Development Of Type 2 Diabetes, Janet Ryan

Nursing | Senior Theses

This paper explores the question: Can interventions focusing on healing the gut microbiome of a prediabetic patient prevent or delay the onset of type 2 diabetes? Diabetes is a major health problem that is becoming the biggest epidemic of the 21^st century. Efforts to derail the progression of disrupted blood glucose metabolism are often futile leaving patients frustrated with a lifelong burden of disease management. Recent studies suggest that collectively the gut microbiome acts as an endocrine organ and that injury to this “organ” can lead to dysfunctional glucose regulation. A comprehensive literature review revealed that further studies are …

Is High-Intensity Focused Electromagnetic Field Stimulation More Effective Than Pelvic Floor Muscle Training In Treating Stress Urinary Incontinence In Women?, Monica Friedman

Nursing | Senior Theses

INTRODUCTION: Stress urinary incontinence, an involuntary loss of urine during physical exertion or effort, affects a disproportionately large number of women worldwide. Although pelvic floor muscle training is the first-line treatment for urinary incontinence, long term adherence is low, and therefore, is usually not an effective treatment. Medications may be costly and aren’t always effective; surgery is invasive and often not appropriate. This condition warrants further studies to find more effective solutions.

OBJECTIVE: To evaluate whether or not focused electromagnetic field therapy is more effective than pelvic floor muscle training in treating stress urinary continence in women.

PROPOSAL FOR FURTHER …

Modulating Matrix Metalloproteases And Inflammation In Huntington’S Disease, Alejandro Lopez Ramirez

Natural Sciences and Mathematics | Biological Sciences Master's Theses

Huntington’s disease (HD) is a rare and incurable autosomal neurodegenerative disease affecting 1-10 in every 100,000 people in the world. There is no cure for HD and treatments available alleviate certain symptoms for short periods of time. Evidence suggests that neuropathology of HD begins with the proteolysis of the mutated Huntingtin (mHTT) protein. A variety of proteases, like the matrix metalloproteases, cleave mHTT creating proteinaceous fragments that are thought to be neurotoxic. As these fragments increase in the brain, the damage to neurons also increases, leading to chronic inflammation due to hyper reactive microglia and astrocytes attempting to minimize and …

Neuroprotection Against Alzheimer’S And Lifespan Extension Induced By Dietary Restriction Are Associated With Metabolomic Changes And Depend On Oxidative Resistance Protein 1 (Oxr1), George W. Brownridge Iii

Natural Sciences and Mathematics | Biological Sciences Master's Theses

Dietary restriction (DR) has been demonstrated to be a robust means of extending the healthspan and lifespan, along with improving cognitive performance in various model organisms from yeast to primates, possibly by mediating neuroprotection. We utilized the Drosophila melanogaster model organism to better understand the molecular pathways that enable DR-induced benefits. By performing a genome-wide associated screening of the Drosophila Genetic Reference Panel (DGRP) that catalogues all natural genetic variants, we discovered that Oxidative resistance protein 1 (OXR1) showed the most significant difference in expression between DR and the inverse intervention of ad libitum (AL). Our research found that OXR1 …

Elucidating The Effects Of Glucose Toxicity On Tauopathy And Aging, Lukas Fluitt

Natural Sciences and Mathematics | Biological Sciences Master's Theses

Diabetes patients are at higher risk of contracting an age-related neurodegenerative disease such as Alzheimer’s disease (AD). However, the mechanisms which link these diseases are poorly understood. We hypothesize that glucose and elevated levels of the glycolysis by product advanced glycation end-products (AGEs), may be involved. AGEs accumulate with age and are elevated in both diabetic and AD patients. Diabetes is a metabolic disorder for which consumption of sugar-rich diets is a major risk factor and is central to etiology in the vast majority of cases.

We show that transgenic C. elegans expressing wild type (WT) human tau fed a …

Determining The Link Between Advanced Glycation Endproducts (Ages), Feeding, And Metabolism, Lauren Wimer

Natural Sciences and Mathematics | Biological Sciences Master's Theses

Reactive a-dicarbonyls (a-DC’s), such as methylglyoxal (MGO), are unavoidable metabolites generated during glycolysis that accumulate with age and have been linked with chronic age-related metabolic diseases such as Diabetes Mellitus. Diabetes Mellitus is generally characterized by peripheral neuropathy and sustained hyperglycemia. Chronic hyperglycemia leads to an increase in glycolysis and a downstream increase in reactive a-DC’s. The human body has a natural method of detoxifying these a-DC’s. Glycolytic cells have enzymes which can detoxify a-DC’s, but if overwhelmed, a-DC’s can accumulate and react non-enzymatically with proteins, lipids and DNA to yield a group of molecules called advanced glycation end-products (AGEs). …

Creating Focused Occupational Therapy Interventions For Clients With Heart Failure In Skilled Nursing Facilities, In Hwa Chae, Camille Marcia Schilling, Elena Ruth Vaccaro

Occupational Therapy | Graduate Capstone Projects

The ultimate goal of the SNF is to help clients stabilize their medical conditions and attain their therapy goals so that they can return home (Orr, Boxer, Dolansky, Allen, & Forman, 2016). However, approximately 27% of heart failure (HF) clients are readmitted to the hospital after being discharged from the SNF (Allen et al., 2011). High readmission rates may be due to the cognitive (Dickson, Tkacs, and Riegel, 2007), psychosocial (Halliday, 2010), and lifestyle barriers (Maeda, Shen, Schwarz, Farrell, & Mallon, 2013) HF clients face. However, interventions in the SNF tend to emphasize activities of daily living (ADLs) and therapeutic …

Are All Instrumental Activities Of Daily Living Equal? A Pilot Study On The Performances Of Adults With Acquired Brain Injury, Crystal Lee, Samantha Schauer, Amy Tam, Yareli Vargas

Occupational Therapy | Graduate Capstone Projects

Aim: To determine if a relationship exists among performances of different instrumental activities of daily living (IADLs) in adults with acquired brain injury (ABI).

Methods: A two-group correlational design was used to examine the relationship among performances in cooking, medication management, and financial management in nine adults with ABI who returned to driving and nine adults with ABI who did not return to driving. The Executive Function Performance Test (EFPT) measured initiation, organization, sequencing, judgment and safety, and completion.

Physiological Responses & Coping Strategies Of Sensory Defensive Adults, Benjamin Cohen, Alexandria Donaldson, Jenny Park-Chan, Jessica Valenzuela

Occupational Therapy | Graduate Capstone Projects

Purpose: The purpose of this study was to learn how adults cope with their sensory defensiveness (SD) and how physiological responses differ between adults who self-report as high SD versus low SD. Methods: In this continuation study participants (age 18-64; n=23) were categorized as low SD (control group; n=9) or high SD (experimental group; n=14) via their Adolescent Adult Sensory Profile (AASP) scores and Sensory Response Questionnaire (SRQ) scores (Brown, & Dunn, 2002 & Wilbarger, 2009). The last nine participants also completed the Coping Strategies Questionnaire (CSQ). All participants partook in the sensory challenge protocol which examined their electrodermal activity …

The Effect Of The Timing Of A Hospice Referral And The Perceived Quality Of Care By The Family, Caitlin Tran

Nursing | Senior Theses

Hospice care is a specialized type of palliative care for patients with a time-limiting illness. Despite its benefits, hospice remains underutilized. A key reason behind the underutilization are untimely referrals, often made during the last weeks or days of the patient’s life. The purpose of this paper is to investigate the existing barriers towards hospice that play into late referrals and its effect on patient/family satisfaction. This information will be examined to propose a pilot research study for further exploration.

An Investigation Of Treatments For The Prevention Of Metabolic Complications For Women Suffering From Polycystic Ovarian Syndrome: Diet, Exercise, Weight Reduction And Herbal Remedies, Brenda Martinez-Puente

Nursing | Senior Theses

The purpose of this research study is to compare the views of traditional versus alternative treatments available to women with Polycystic Ovarian Syndrome (PCOS) suffering from metabolic complications. Alternative treatments include diet, exercise, herbal remedies, or any combination of the three. Pharmacological interventions for the conditions associated with PCOS such as metformin, used to control glucose levels, and clomiphene, used to treat infertility. Through the literature review, articles show herbs and plant products to have similar mechanisms of actions as the pharmacological interventions, but with less side effects. For example, cinnamon was shown to increase insulin sensitivity and pomegranate juice …

Supporting Positive Lifestyle Changes Among Patients With Diabetes Mellitus Type 2, Alison Tynan

Nursing | Senior Theses

The following thesis is a compilation of literature reviewed to formulate background research for a pilot study. The literature reviewed pertains to the potential benefit of added case management for patients with diabetes mellitus type 2. A proposed pilot study, based off of this research, aims to identify topics, tools, facts, and changes that can be made to case management to improve not just the biological aspects, like HbA1c levels, but the mental and emotional as well to allow for whole person care.

The primary question being asked is “what types of support do people with diabetes mellitus type 2 …

Emergency Preparedness And Perceptions Of Resident University Students: Literature Review, Study Proposal & Impact Of Pandemic Crisis On Research, Madelyn Turner

Nursing | Senior Theses

Emergency preparedness is an essential step in mitigating negative impacts of disasters, especially in an area affected by wildfires, power shutoffs, earthquakes, and flooding. Dominican University of California resides within Marin County, and has experienced emergencies in the past. Students are expected to prepare themselves to survive independently for 3-5 days. As previous research has shown, college students often do not meet this expectation. This proposed study will assess the current preparedness levels of students living on Dominican’s campus. It will also determine how perceptions of emergency readiness contribute to actual preparedness. Data collection was interrupted by the COVID-19 pandemic, …

Neonatal Health Outcomes And Access To Care, Riki Desjarlais

Nursing | Senior Theses

This paper will review existing research regarding the importance of prenatal healthcare. The research included covers the barriers existing to pregnant mothers and the consequences these barriers pose for mothers and babies with prenatal care that is unobtainable or undesired. This paper will also review current interventions that have provided under-served mothers with the resources they need to better ensure a healthy pregnancy and delivery. Research analyzing mother’s attitudes and beliefs regarding prenatal care will be addressed in addition to how these beliefs may attribute to the health outcomes of their babies. Finally, this paper will include my own research …

The Relationship Between Low Socioeconomic Status And Mortality Rates Of School Age Children Related To Motor Vehicle Accidents, Rubi Calderon-Rodriguez

Nursing | Senior Theses

The purpose of this study is to assess nurses’ perceptions on the relationship between low socioeconomic status and high mortality rates of children due to motor vehicle accidents(MVAs). MVAs are the leading cause of death among children four years and older. Studies reviewed in this paper support that low socioeconomic status is associated with high child mortality rates caused by motor vehicle accidents. Factors contributing to these high mortality rates include: the lack of or improper use of restraints, low parental education attainment levels, black or Hispanic race, and environmental risks of low socioeconomic areas. A mixed methods study is …

Nurses' Perceptions Of The Impact Of The Electronic Health Record On Clinical Decision-Making, Angela Dizon Garcia

Nursing | Senior Theses

This study explored the impact of electronic health record (EHR) use on registered nurses’ critical thinking, decision-making, and quality of care for hospitalized patients. Based on literature review, the researcher maintained a consistent definition of critical thinking and decision-making and how the use of the EHR affects these two complex yet significant processes. A descriptive survey design to assessed registered nurses’ attitudes and perceptions of how the EHR influences their clinical decision-making when caring for patients in an acute care setting. It found that nurses are aware that the EHR is beneficial, yet they often feel that electronically charting can …

Hospitalization And Child Development: Effects On Sleep, Developmental Stages, And Separation Anxiety, Vanessa Cahayag

Nursing | Senior Theses

Childhood development has been an important topic for those in the medical field, as well as parents. The way a child develops can determine the way they act, think, and mature. Hospitalizations, acute and chronic, may affect the process of proper child development. Literature is reviewed to support the presented pilot study that focuses on the immediate effects of hospitalization on a child’s sleep disturbances, regression to lower developmental stages, and separation anxiety. The collected data determined the need for refinement of the survey tool and presented with possible correlations between hospitalizations and childhood development.

Barriers To Patient-Centered Care For Dementia Clients In The Long-Term Living Setting, Shaina Gaba

Nursing | Senior Theses

When caring for people with severe dementia, the concept of the person being central is increasingly advocated in clinical practice. Person-centered care acknowledges autonomy in all facets of care. Recent studies examine behavioral changes in individuals with dementia and how health care teams address these alterations. Health care providers are vital for effective holistic management. Therefore, this review focuses on the current knowledge regarding care goals, practices, and perceptions of the client battling with cognitive decline. A literature review ascertains that clients with dementia respond to interventions and have decreased negative health outcomes, when providers ensure values and needs are …

Social Participation In College Students With Chronic Pain, Megan Chamberlain, Megan Chinn, Jennifer Pineda, Camille Santiago, Jamie Spitzer, Patricia Tran

Occupational Therapy | Graduate Capstone Projects

College students with chronic pain often experience difficulty engaging in social activities both on and off campus due to stigma, misconceptions, or social exclusions (Culp & Rojas-Guyler, 2014). To fully understand the barriers to social engagement, the researchers used a qualitative phenomenological approach and semi-structured interviews to explore the lived experiences of 15 college students with chronic pain (pain lasting more than six months). Four main themes were identified: the additional influence of personality on social participation; stigma and lack of understanding of chronic pain; the “domino effect” of pain impacting energy, sleep quality, and ability to function throughout the …

Effects Of Shift Length On Nursing Staff’S Productivity, Safety, And Well-Being, Victoria Sivesind

Nursing | Senior Theses

In this thesis the relationship between normal shift length for nurses and fatigue, burnout, intention to leave job, and patient outcomes and satisfaction. A review of literature has been done and conclusions have been made about the previous research reviewed in the thesis. A proposal for further research has been included and details how the author plans to provide further clarification to the questions at hand in order to better clinical nursing practice for the future. The proposed study includes sending out a survey to members of the Sigma Theta Tau Honors Nursing Society. It will inquire about shift length, …

Impacts Of Assistive Technology Applications In Higher Education For Students With And Without Disabilities, Christine Jacob, Michelle Morello, Cayla Chapman, Grace Erhardt, Erin Camarena, Sara Delucchi, Bethany Young

Occupational Therapy | Graduate Capstone Projects

Current trends in higher education include an increased enrollment of students who have a disability and a rising trend of technology use within the classroom. Assistive technology (AT) has been shown to enhance academic success and influence learning strategies. Furthermore, the combination of AT and individualized support has the potential to promote and enhance engagement in meaningful occupations, such as participation in school, for individuals with and without disabilities. However, the procurement of AT alone can often have less impact than AT combined with individualized support. Occupational therapists (OT) can play a significant role in HE providing training and individualized …

Evaluation Of User Interface In Drive Focus® Application, Bailey Kiser, Paul S. Peritos, Noreen Hasan, Anjelica J. Collins

Occupational Therapy | Graduate Capstone Projects

Technology is used in healthcare settings to aid clinicians in accessing client information, researching data, and enhancing communication with the client and other healthcare team members. In order for an app to best support client engagement, the app needs to have a well-developed user interface design There are four main aspects of user interface design, context, fidelity, accessibility, and consistency. The Drive Focus® application (app) is designed to identify how an individual recognizes, prioritizes, and reacts to information during real-world driving simulations. The Drive Focus® app has efficacy and feasibility, however, the user interface design has never been assessed. Therefore, …

Interrelationship Between Sensory Modulation, Altered Interoceptive Awareness, And Anxiety And Impacts On Quality Of Life, Sara Laughter, Vanessa Mitchell, Natalie Nguyen, Christine Kim

Occupational Therapy | Graduate Capstone Projects

OBJECTIVE: The negative impacts of sensory modulation disorder (SMD), anxiety, and altered interoceptive awareness (AIA) on daily occupations reinforced the need for the study of the relationship between sensory modulation, anxiety, and interoception in typical adults. Understanding the relationship between the three constructs is the first step in the ultimate goal of developing effective intervention and treatment measures.

METHODS: This cross-sectional, exploratory study analyzed the relationship between scores on four self-report measures in an online survey: State Trait Anxiety Inventory (STAI), 36-Item Short Form Health Survey (SF-36), Sensory Responsiveness Questionnaire (SRQ), and Multidimensional Assessment of Interoceptive Awareness, Version 2 (MAIA-2). …

Self Perception Of Dental Esthetics And Its Impact Among Adults Self Esteem In Sonoma And Marin County, Carolina Camacho

Global Public Health | Senior Theses

Background

One out of four American adults refrain from smiling attributable to the condition of their dentofacial area. The aim of this study was to analyze the relationship between self-perception of dental esthetics and individual self-esteem among Sonoma and Marin County adults. Analytical concepts and processes were utilized to determine and describe the statistical significance of this plausible association.

Methods

In order to assess the interconnection of this relationship from an analytical approach, an observational study design method was utilized consisting of both a quantitative and qualitative analysis. A total of 163 participants consensually responded to an online questionnaire containing …

Fatal & Non-Fatal Opioid Overdoses In Marin County: Using Ems And County Data To Locate The Presence Of Fentanyl, Naloxone Distribution, Repeated Overdoses, And Demographics, Josette Rojo

Global Public Health | Senior Theses

Background. In recent years, the United States has been greatly affected by prescription drug overdose deaths, 68% of which are caused by opioids. Like many communities nationwide, Marin County in California is deeply affected by the opioid epidemic with accidental overdose being one of the leading causes of injury-related death. This study examines how fatal and non-fatal opioid overdoses in Marin County are associated with factors such as suspected fentanyl involvement, naloxone administration (EMS), and repeat overdose events.

Methods. A cross-sectional study was conducted by Marin County’s Health and Human Services using data collected from EMS dispatch calls and vital …

The Effect Of Dance Movement Therapy On The Mood Of Hospitalized Psychiatric Adolescents, Amy Chiu

Nursing | Senior Theses

Mental illness in children has increased over all aspects throughout the years to right now (CDC, 2019). Many of these children do get treatment for these disorders but there are still a percent that do not receive any treatment or find effective ways to maintain non-pharmaceutical alternatives for mood stabilization. The alternative therapies that are introduced in hospital settings plays a role in allowing for alternative therapies to be apart of the treatment plan for patients. Dance Movement therapy (DMT) is an alternative therapy that uses movement to conduct change in patient’s emotions based on their own choices of movement …

Participation In Mindfulness-Based Stress Reduction Therapy On The Immune Function Of Survivors Of Breast Cancer: A Literature Review And Pilot Study For Clinical Practice, Bianca Marteja

Nursing | Senior Theses

A review of current literature presented in this work suggests that MBSR participation results in NKCA, T-cell and B-cell restoration as well as a reduction in inflammatory biomarkers. While results from these studies are statistically significant, they are, however, relatively small. Furthermore, the reliability and one’s ability to generalize study findings from this literature review is limited by consistently small sample sizes, high attrition, differing forms of MBSR application, and inconsistent adherence to MBSR home practices.

The distribution of a 10-point survey using likert scales occured in a pilot study associated with the aforementioned literature review; this survey evaluated registered …