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Suicide

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Full-Text Articles in Medicine and Health Sciences

Implementation Of A Standardized Suicide Screening Process In A University Student Health Clinic: A Quality Improvement Project, Addie Grace Strong, Kathryn Dambrino, R. David Phillippi, Linda Wofford Apr 2024

Implementation Of A Standardized Suicide Screening Process In A University Student Health Clinic: A Quality Improvement Project, Addie Grace Strong, Kathryn Dambrino, R. David Phillippi, Linda Wofford

DNP Scholarly Projects

Background: Suicide is a leading cause of death among college age students, prompting the need for evidence-based screening tools like the Columbia Suicide Severity Rating Scale (C-SSRS) to enable early detection and timely intervention. Inconsistencies in suicide screening may pose a risk of missed intervention opportunities. This Doctor of Nursing Practice project specifically aimed to improve the quality and consistency of suicide screening in a university student health clinic by implementing the C-SSRS tool into the clinic workflow during mental health appointments. Methods: Employing a quality improvement framework, this scholarly project followed the Institute for Healthcare Improvement Model for Improvement …


Implementation Of The Columbia-Suicide Severity Rating Scale At An Outpatient Mental Health Practice To Increase Provider Confidence In Identifying Suicide Risk, Lauren Reed May 2023

Implementation Of The Columbia-Suicide Severity Rating Scale At An Outpatient Mental Health Practice To Increase Provider Confidence In Identifying Suicide Risk, Lauren Reed

Doctor of Nursing Practice Final Manuscripts

Introduction: The purpose of this evidence-based Doctor of Nursing Practice project was to implement the Columbia-Suicide Severity Rating Scale (C-SSRS) as part of routine patient assessment at an outpatient mental health practice to increase the likelihood of identifying clients at risk for suicidal behavior and increase provider confidence in screening for suicidal behavior. The study site is a Southern California-based outpatient mental health practice that employs a variety of clinicians, including psychiatric-mental health nurse practitioners, to provide mental health care to clients across the lifespan.

Background: Approximately 57% of individuals who die by suicide had at least one contact with …


Exploring Sociodemographic Correlates Of Suicide Stigma In Australia: Baseline Cross-Sectional Survey Findings From The Life-Span Suicide Prevention Trial Studies, Lisa N. Sharwood, Alison L. Calear, Philip J. Batterham, Michelle Torok, Lauren Mcgillivray, Demee Rheinberger, Stephanie Zeritis, Tuguy Esgin, Fiona Shand Feb 2023

Exploring Sociodemographic Correlates Of Suicide Stigma In Australia: Baseline Cross-Sectional Survey Findings From The Life-Span Suicide Prevention Trial Studies, Lisa N. Sharwood, Alison L. Calear, Philip J. Batterham, Michelle Torok, Lauren Mcgillivray, Demee Rheinberger, Stephanie Zeritis, Tuguy Esgin, Fiona Shand

Research outputs 2022 to 2026

The risk of suicidal behaviour in Australia varies by age, sex, sexual preference and Indigenous status. Suicide stigma is known to affect suicide rates and help-seeking for suicidal crises. The aim of this study was to investigate the sociodemographic correlates of suicide stigma to assist in prevention efforts. We surveyed community members and individuals who had attended specific emergency departments for suicidal crisis. The respondents were part of a large-scale suicide prevention trial in New South Wales, Australia. The data collected included demographic characteristics, measures of help-seeking and suicide stigma. The linear regression analyses conducted sought to identify the factors …


School Division Policies Related To Suicide Prevention And Response, David Naff, Fatemah A. Khawaji, Morgan Meadowes, Jill Flynn, Meg Sheriff, Lauren Powell, Lisa Gwyn, Tameka Burroughs, Jean Samuel Jan 2023

School Division Policies Related To Suicide Prevention And Response, David Naff, Fatemah A. Khawaji, Morgan Meadowes, Jill Flynn, Meg Sheriff, Lauren Powell, Lisa Gwyn, Tameka Burroughs, Jean Samuel

MERC Publications

Suicide is one of the leading causes of death among youth age 10-19, and is an increasing concern in the wake of COVID-19. K-12 schools are crucial spaces for offering mental health support to students, and can implement policies to help prevent suicidal thoughts and behaviors. This MERC research and policy brief focuses on education policy related to suicide prevention and response. It is structured to answer five questions: 1) What are recent trends in youth suicide? 2) What does research show about school division policies that are effective in suicide prevention and response? 3) What policies in Virginia and …


Multifactorial Depression In A Peripartum Patient, Subsequent Suicide Attempt, Treatment, And Recovery, Connor Farnham, Patricia Westmoreland, Ryan Spilman, Natasha Fazel, Daniel Grine Jan 2023

Multifactorial Depression In A Peripartum Patient, Subsequent Suicide Attempt, Treatment, And Recovery, Connor Farnham, Patricia Westmoreland, Ryan Spilman, Natasha Fazel, Daniel Grine

Continental, MidAmerica, & Mountain Divisions Research Day 2023

No abstract provided.


Understanding Suicide And Its Prevention In The Indian Context: Mental Health Perspective, Dushad Ram, Akash Mathew, Muath A Alammar Dec 2022

Understanding Suicide And Its Prevention In The Indian Context: Mental Health Perspective, Dushad Ram, Akash Mathew, Muath A Alammar

International Journal of Health and Allied Sciences

In India, suicide research has largely concentrated on the prevalence, method, psychological, and demographic risk factors. Suicide processes, paradigms, prevention strategies, and other features of suicide that are common in the West may not be applicable in India. It is vital to study potential underlying processes, various suicide prevention methods, and suicide prevention in general, as well as what more work has to be done in the Indian context. Suicide, on the other hand, is a cross-sectoral public health issue that demands collaboration across all key sectors, and its prevention should engage all stakeholders in India.


Patterns Of Suicide And Self-Harm In Pakistan: A Retrospective Descriptive Study Protocol, Nargis Asad, Shahina Pirani, Summaiya Tariq, Asra Qureshi, Mohammad Zaman, Mustafa Aslam, Farhat Mirza, Murad M. Khan Nov 2022

Patterns Of Suicide And Self-Harm In Pakistan: A Retrospective Descriptive Study Protocol, Nargis Asad, Shahina Pirani, Summaiya Tariq, Asra Qureshi, Mohammad Zaman, Mustafa Aslam, Farhat Mirza, Murad M. Khan

Department of Psychiatry

Introduction: Suicide is a major global public health problem. Low-income and middle-income countries contribute 78% of all suicidal deaths. Pakistan, a South Asian country, lacks official statistics on suicides at national level. Statistics on suicide are neither collected nationally nor published in the annual national morbidity and mortality surveys. Medicolegal reports on suicides and self-harm are extremely rich and important source of information but greatly underused in Pakistan. We aim to examine the patterns of suicides and self-harm retrospectively in patients who were registered with medicolegal centres (MLCs) in Karachi, during the period January 2017 to December 2021.
Methods and …


Systematic Suicide Screening In A General Hospital Setting: Process And Updated Results 10-Year Data Review, Evan Becker, Sarah Williams, Udema Millsaps, Andres Pumariega, Kolin Good, Eduardo Espiridion Oct 2022

Systematic Suicide Screening In A General Hospital Setting: Process And Updated Results 10-Year Data Review, Evan Becker, Sarah Williams, Udema Millsaps, Andres Pumariega, Kolin Good, Eduardo Espiridion

Tower Health Research Day

No abstract provided.


Suicide Numbers During The First 9-15 Months Of The Covid-19 Pandemic Compared With Pre-Existing Trends: An Interrupted Time Series Analysis In 33 Countries, Jane Pirkis, David Gunnell, Sangsoo Shin, Marcos Del Pozo-Banos, Vikas Arya, Pablo Analuisa Aguilar, Louis Appleby, S. M. Yasir Arafat, Ella Arensman, Murad Khan Sep 2022

Suicide Numbers During The First 9-15 Months Of The Covid-19 Pandemic Compared With Pre-Existing Trends: An Interrupted Time Series Analysis In 33 Countries, Jane Pirkis, David Gunnell, Sangsoo Shin, Marcos Del Pozo-Banos, Vikas Arya, Pablo Analuisa Aguilar, Louis Appleby, S. M. Yasir Arafat, Ella Arensman, Murad Khan

Department of Psychiatry

Background: Predicted increases in suicide were not generally observed in the early months of the COVID-19 pandemic. However, the picture may be changing and patterns might vary across demographic groups. We aimed to provide a timely, granular picture of the pandemic's impact on suicides globally.
Methods: We identified suicide data from official public-sector sources for countries/areas-within-countries, searching websites and academic literature and contacting data custodians and authors as necessary. We sent our first data request on 22nd June 2021 and stopped collecting data on 31st October 2021. We used interrupted time series (ITS) analyses to model the association between the …


The Protective Potential Of Family Relationship Strength As It Relates To Suicidal Thoughts And Behaviors In Ace-Exposed Adolescents And Emerging Adults, Collin Wright Mar 2022

The Protective Potential Of Family Relationship Strength As It Relates To Suicidal Thoughts And Behaviors In Ace-Exposed Adolescents And Emerging Adults, Collin Wright

Student Works

Introduction: Adverse Childhood Experiences (ACEs) are known to cause higher incidences of Suicidal Thoughts and Behaviors (STBs) in young people. Family Relationship Strength (FRS) is a known protective factor against STBs. However, there is little research on the protective nature of FRS once ACEs have been experienced by a young person. The aim of our analysis is to examine whether the strong protective nature of FRS holds true even in ACE-exposed youth. Methods: A sample of 139 patients at the Brigham Young University Comprehensive Clinic (aged 12-25) was obtained from the BYU Marriage and Family Therapy Practice Research Network. Linear …


Impact Of Cognitive Behavioral Therapy On Military Suicide Rates, Madison Lett, Jamia Bird Jan 2022

Impact Of Cognitive Behavioral Therapy On Military Suicide Rates, Madison Lett, Jamia Bird

Theses, Dissertations and Capstones

Introduction: Suicide has been labeled a serious public health dilemma in the United States. Military personnel have suicide rates greater than non-military individuals. Cognitive Behavioral Therapy has been used as a means to help military personnel to overcome suicidal thoughts and feelings.

Purpose of the Study: The purpose of this study was to analyze the effect of Cognitive Behavioral Therapy on military patients’ mental health and how it affects the rate of suicidal ideation, suicide attempts, and deaths by suicide in military patients.

Methodology: This study utilized a literature review and a semi-structured interview with a Veteran Affairs social worker. …


Psychological Autopsy Study And Risk Factors For Suicide In Muslim Countries, S M Yasir Arafat, Murad M. Khan, Vikas Menon, Syeda Ayat-E-Zainab Ali, Mohsen Rezaeian, Sheikh Shoib Oct 2021

Psychological Autopsy Study And Risk Factors For Suicide In Muslim Countries, S M Yasir Arafat, Murad M. Khan, Vikas Menon, Syeda Ayat-E-Zainab Ali, Mohsen Rezaeian, Sheikh Shoib

Department of Psychiatry

Background: Suicide and risk factors have been poorly studied in the Muslim-majority countries that hinder the formulation of prevention strategies and affect suicide prevention eventually.
Objectives: We aimed at identifying and analyzing the psychological autopsy studies assessing the risk factors for suicide conducted in Muslim-majority countries.
Methods: We did a search to trace all the available psychological autopsy studies in the Muslim countries with the search term "psychological autopsy study in Muslim countries." We also checked the available bibliographies to identify the psychological autopsy studies in the Muslim countries so that all the possible studies could be included.
Results: Out …


Medical Schools Ignore The Nature Of Consciousness At Great Cost, Anoop Kumar Jul 2021

Medical Schools Ignore The Nature Of Consciousness At Great Cost, Anoop Kumar

Journal of Wellness

The essential question of the relationship between consciousness and matter is ignored in medical school curricula, leading to a machine-like view of the human being that contributes to physician burnout and intellectual dissatisfaction. The evidence suggesting that the brain may not be the seat of consciousness is generally ignored to preserve the worldview of the primacy of matter. By investigating new frameworks detailing the nature of consciousness at different levels of hierarchy, we can bring intellectual rigor to a once opaque subject that supports a fundamental reality about our experience: We are human beings, not only human bodies.


Toxoplasma Gondii, Suicidal Behavior, And Intermediate Phenotypes For Suicidal Behavior, Teodor T. Postolache, Abhishek Wadhawan, Dan Rujescu, Andrew J. Hoisington, Aline Dagdag, Enrique Baca-Garcia, Christopher A. Lowry, Olaoluwa O. Okusaga, Lisa A. Brenner Jun 2021

Toxoplasma Gondii, Suicidal Behavior, And Intermediate Phenotypes For Suicidal Behavior, Teodor T. Postolache, Abhishek Wadhawan, Dan Rujescu, Andrew J. Hoisington, Aline Dagdag, Enrique Baca-Garcia, Christopher A. Lowry, Olaoluwa O. Okusaga, Lisa A. Brenner

Faculty Publications

Within the general literature on infections and suicidal behavior, studies on Toxoplasma gondii ( T. gondii ) occupy a central position. This is related to the parasite's neurotropism, high prevalence of chronic infection, as well as specific and non-specific behavioral alterations in rodents that lead to increased risk taking, which are recapitulated in humans by T. gondii's associations with suicidal behavior, as well as trait impulsivity and aggression, mental illness and traffic accidents. This paper is a detailed review of the associations between T. gondii serology and suicidal behavior, a field of study that started 15 years ago with our …


Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth May 2021

Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth

Publications

Suicide is the 10th leading cause of death in the U.S (1999-2019). However, predicting when someone will attempt suicide has been nearly impossible. In the modern world, many individuals suffering from mental illness seek emotional support and advice on well-known and easily-accessible social media platforms such as Reddit. While prior artificial intelligence research has demonstrated the ability to extract valuable information from social media on suicidal thoughts and behaviors, these efforts have not considered both severity and temporality of risk. The insights made possible by access to such data have enormous clinical potential - most dramatically envisioned as a trigger …


Reducing Patient Risk For Suicidal Behaviors With A Safety Bundle Of Best Practices With Non-Psychiatric Patients, Olayemi Akindele Apr 2021

Reducing Patient Risk For Suicidal Behaviors With A Safety Bundle Of Best Practices With Non-Psychiatric Patients, Olayemi Akindele

Student Scholarly Projects

Practice Problem: Suicide is a public health condition that affects people globally. The increased suicidal behaviors of patients in a medical-surgical unit demanded an effective screening protocol to identify high-risk patients.

PICOT: In patients 18 years and older on a medical-surgical unit, does the implementation of the Columbia Suicide Severity Rating Scale (C-SSRS) tool and application of a Safety Bundle of Best Practices (SBBP) increase early identification of suicide risk with decreased patient self-harm behaviors, compared to the current standard practice of no assessment tool or safety bundle of best practices within 12 weeks?

Evidence: Ten studies served as evidence …


Sexual Violence And Suicide In Bangladesh, S M Yasir Arafat, Murad M. Khan Mar 2021

Sexual Violence And Suicide In Bangladesh, S M Yasir Arafat, Murad M. Khan

Department of Psychiatry

No abstract provided.


Risk Factors For Suicide In Bangladesh: Case-Control Psychological Autopsy Study, S M Yasir Arafat, M A. Mohit, Mohammad S I. Mullick, Russell Kabir, Murad M. Khan Jan 2021

Risk Factors For Suicide In Bangladesh: Case-Control Psychological Autopsy Study, S M Yasir Arafat, M A. Mohit, Mohammad S I. Mullick, Russell Kabir, Murad M. Khan

Department of Psychiatry

Background: Suicide is an important, understudied public health problem in Bangladesh, where risk factors for suicide have not been investigated by case-control psychological autopsy study.
Aims: To identify the major risk factors for suicide in Dhaka, Bangladesh.
Methods: We designed a matched case-control psychological autopsy study. We conducted a semi-structured interview with the next-of-kin of 100 individuals who died by suicide and 100 living controls, matched for age, gender and area of residence. The study was conducted from July 2019 to July 2020.
Results: The odds ratios for the risk factors were 15.33 (95% CI, 4.76-49.30) for the presence of …


The Moderating Role Of Psychological Inflexibility In The Relationship Between Minority Stress, Substance Misuse, And Suicidality In Lgb+ Adolescents, Sean N. Weeks Dec 2020

The Moderating Role Of Psychological Inflexibility In The Relationship Between Minority Stress, Substance Misuse, And Suicidality In Lgb+ Adolescents, Sean N. Weeks

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Adolescence is a difficult time, especially for those who do not identify as heterosexual (e.g., gay, lesbian, bisexual, asexual, pansexual; LGB+). Increased rates of substance abuse and suicidality are well documented outcomes that tend to be worse in the LGB+ adolescent community than in mainstream groups. Minority stress, the effect of unique stressors experienced by those in the LGB+ community explained by external and societal influences, has been accepted within the research community as a theory used to explain the health disparities seen in this group. This study proposed a possible further explanation, in addition to minority stress, that helps …


Peer Intervention With Suicidal Disclosures On Social Media: Does The Bystander Effect Play A Role?, Carissa M. Orlando Jul 2020

Peer Intervention With Suicidal Disclosures On Social Media: Does The Bystander Effect Play A Role?, Carissa M. Orlando

Theses and Dissertations

Suicide is an increasing public health concern in adolescents and young adults, and many individuals discuss mental health concerns with friends in lieu of professional avenues. Thus, peers can serve as valuable gatekeepers for friends experiencing suicidality. The prevalence of social networking websites means that individuals are likely to encounter suicidal disclosures on the internet, but little research has investigated if young adults possess the skills and motivation to intervene in these contexts. Additionally, there have been virtually no investigations into how the presence of other online users impacts intervention behavior—in short, if there exists a bystander effect. This study …


Bastards' Road, William L. Blizek Feb 2020

Bastards' Road, William L. Blizek

Journal of Religion & Film

This is a film review of Bastards' Row (2019) directed by Brian Morrison.


Genome-Wide Dna Methylation Meta-Analysis In The Brains Of Suicide Completers, Stefania Policicchio, Sam Washer, Joana Viana, Artemis Iatrou, Joe Burrage, Eilis Hannon, Gustavo Tureki, Zachary Kaminsky, Jonathan Mill, Emma L. Dempster, Therese Murphy Jan 2020

Genome-Wide Dna Methylation Meta-Analysis In The Brains Of Suicide Completers, Stefania Policicchio, Sam Washer, Joana Viana, Artemis Iatrou, Joe Burrage, Eilis Hannon, Gustavo Tureki, Zachary Kaminsky, Jonathan Mill, Emma L. Dempster, Therese Murphy

Articles

Suicide is the second leading cause of death globally among young people representing a significant global health burden. Although the molecular correlates of suicide remains poorly understood, it has been hypothesised that epigenomic processes may play a role. The objective of this study was to identify suicide-associated DNA methylation changes in the human brain by utilising previously published and unpublished methylomic datasets. We analysed prefrontal cortex (PFC, n = 211) and cerebellum (CER, n = 114) DNA methylation profiles from suicide completers and non-psychiatric, sudden-death controls, meta-analysing data from independent cohorts for each brain region separately. We report evidence for …


Subanesthetic Iv Ketamine Reduces Acute Suicidal Ideation In Patients With Mood Disorders, Kimberly Jenko, Jack Anzilotti Dec 2019

Subanesthetic Iv Ketamine Reduces Acute Suicidal Ideation In Patients With Mood Disorders, Kimberly Jenko, Jack Anzilotti

Physician Assistant Capstones, 2016 to 2019

Background. Depression and suicide are common in the United States and present a significant problem in the healthcare landscape. Currently, there are few options that can rapidly reduce suicidal ideation in patients with depression. Ketamine, a glutamate N-methyl-D-aspartate (NMDA) receptor antagonist, has been shown to reduce acute suicidality in patients with depression. Previous studies have a reduction of suicidal ideation compared to saline placebo, but few studies have shown a significant effect compared to a similar psychoactive drug such as midazolam.

Method. A search of PubMed and PsychNET was performed in September 2018 using the terms “ketamine,” “suicide,” …


Masculinity And Suicidal Desire In A Community Sample Of Homeless Men: Bringing Together Masculinity And The Interpersonal Theory Of Suicide, Matthew C. Genuchi Oct 2019

Masculinity And Suicidal Desire In A Community Sample Of Homeless Men: Bringing Together Masculinity And The Interpersonal Theory Of Suicide, Matthew C. Genuchi

Psychological Sciences Faculty Publications and Presentations

Men’s high suicide death rates are likely associated with a range of factors, notably men’s conformity to predominant masculine gender role norms and men’s gender-related attitudes toward suicide death based on those norms. The purpose of this study was to investigate how two models integrating men’s conformity to hegemonic masculine gender role norms, perceived burdensomeness, and thwarted belongingness predict the existence and severity of suicidal ideation in a sample of men at high risk for suicide, homeless men. The study results indicated that multiple norms were predictive of the existence or severity of suicidal ideation while perceived burdensomeness predicted both …


A Letter To My Departed Niece, * Anonymous * Jul 2019

A Letter To My Departed Niece, * Anonymous *

Journal of Patient-Centered Research and Reviews

The following piece was written in the weeks following the death of the author’s niece. It is an attempt to explore how we as a society handle health crises differently for medical versus mental health diagnoses.


Contextual Factors Associated With County-Level Suicide Rates In The United States, 1999 To 2016, Danielle L. Steelsmith, Cynthia A. Fontanella, John V. Campo, Jefferey A. Bridge, Keith L. Warren, Elisabeth D. Root Jan 2019

Contextual Factors Associated With County-Level Suicide Rates In The United States, 1999 To 2016, Danielle L. Steelsmith, Cynthia A. Fontanella, John V. Campo, Jefferey A. Bridge, Keith L. Warren, Elisabeth D. Root

Faculty & Staff Scholarship

Importance Understanding geographic and community-level factors associated with suicide can inform targeted suicide prevention efforts.

Objectives To estimate suicide rates and trajectories, assess associated county-level contextual factors, and explore variation across the rural-urban continuum.

Design, Setting, and Participants This cross-sectional study included all individuals aged 25 to 64 years who died by suicide from January 1, 1999, to December 31, 2016, in the United States. Spatial analysis was used to map excess risk of suicide, and longitudinal random-effects models using negative binomial regression tested associations of contextual variables with suicide rates as well as interactions among county-level contextual variables. Data …


Depression And The Relationship Between Sleep Disturbances, Nightmares, And Suicidal Ideation In Treatment-Seeking Canadian Armed Forces Members And Veterans, Don Richardson, Lisa King, Kate St. Cyr, Philippe Shnaider, Maya L. Roth, Felicia Ketcheson, Ken Balderson, Jon D. Elhai Jun 2018

Depression And The Relationship Between Sleep Disturbances, Nightmares, And Suicidal Ideation In Treatment-Seeking Canadian Armed Forces Members And Veterans, Don Richardson, Lisa King, Kate St. Cyr, Philippe Shnaider, Maya L. Roth, Felicia Ketcheson, Ken Balderson, Jon D. Elhai

MacDonald Franklin OSI Research Centre

Background: Research on the relationship between insomnia and nightmares, and suicidal ideation (SI) has produced variable findings, especially with regard to military samples. This study investigates whether depression mediated the relationship between: 1) sleep disturbances and SI, and 2) trauma-related nightmares and SI, in a sample of treatment-seeking Canadian Armed Forces (CAF) personnel and veterans (N = 663). Method: Regression analyses were used to investigate associations between sleep disturbances or trauma-related nightmares and SI while controlling for depressive symptom severity, posttraumatic stress disorder (PTSD) symptom severity, anxiety symptom severity, and alcohol use severity. Bootstrapped resampling analyses were used to …


A Review Of The Mechanism Of Antagonism Of N-Methyl-D-Aspartate Receptor By Ketamine In Treatment-Resistant Depression, Yasar Sattar, John Wilson, Ali M. Khan, Mahwish Adnan, Daniel Azzopardi Larios, Shristi Shrestha, Quazi Rahman, Zeeshan Mansuri, Ali Hassan, Nirav B. Patel May 2018

A Review Of The Mechanism Of Antagonism Of N-Methyl-D-Aspartate Receptor By Ketamine In Treatment-Resistant Depression, Yasar Sattar, John Wilson, Ali M. Khan, Mahwish Adnan, Daniel Azzopardi Larios, Shristi Shrestha, Quazi Rahman, Zeeshan Mansuri, Ali Hassan, Nirav B. Patel

School of Medicine Publications and Presentations

The biochemical processes involved in depression go beyond serotonin, norepinephrine, and dopamine. The N-methyl-D-aspartate (NMDA) receptor has a major role in the neurophysiology of depression. Ketamine, one of the prototypical NMDA antagonists, works rapidly in controlling depressive symptoms, including acutely suicidal behavior, by just a single injection. Ketamine may rapidly increase the glutamate levels and lead to structural neuronal changes. Increased neuronal dendritic growth may contribute to synaptogenesis and an increase in brain-derived neurotrophic factor (BDNF). Activation of the mechanistic target of rapamycin (mTOR), as well as increased levels of BDNF, may increase long-term potentiation and result in an improvement …


Social Work Trauma Interventions: Dialectical Behavioral Therapy, Kassie Baumann May 2018

Social Work Trauma Interventions: Dialectical Behavioral Therapy, Kassie Baumann

Senior Honors Theses

According to Lynne Weilart (2013), in her article on the reasons why people seek out therapy, trauma is the number one reason people attend counseling. Many different trauma-informed approaches are designed specifically to address the consequences of trauma and to facilitate healing. Some of these approaches are as follows: Cognitive Behavioral Therapy (CBT); Dialectical Behavioral Therapy (DBT);Mentalization Based Therapy (MBT); Trauma Systems Therapy (TST); Trauma Assessment Pathway (TAP); and Attachment, Self-Regulation, and Competency (ARC) (de Arellano, Danielson, Ko, & Sprauge, 2008). The effectiveness of each trauma intervention will be examined. DBT is one of these trauma interventions that is growing …


A Randomized Controlled Dosing Study Of Iyengar Yoga And Coherent Breathing For The Treatment Of Major Depressive Disorder: Impact On Suicidal Ideation And Safety Findings, Maren Nyer, Patricia Gerbarg, Marisa M. Silveri, Jennifer Johnston, Tammy M. Scott, Maya Nauphal, Liz Owen, Greylin H. Nielsen, David Mischoulon, Richard P. Brown, Maurizio Fava, Chris C. Streeter Apr 2018

A Randomized Controlled Dosing Study Of Iyengar Yoga And Coherent Breathing For The Treatment Of Major Depressive Disorder: Impact On Suicidal Ideation And Safety Findings, Maren Nyer, Patricia Gerbarg, Marisa M. Silveri, Jennifer Johnston, Tammy M. Scott, Maya Nauphal, Liz Owen, Greylin H. Nielsen, David Mischoulon, Richard P. Brown, Maurizio Fava, Chris C. Streeter

NYMC Faculty Publications

BACKGROUND: Yoga interventions offer promise for the treatment of major depressive disorder (MDD), yet their safety and potential impact on suicidal ideation (SI) have not been well documented. This study evaluated the safety of a randomized controlled dose-finding trial of Iyengar yoga plus coherent breathing for individuals with MDD, as well as the potential effects of the intervention on SI without intent. METHODS: Participants with Beck Depression Inventory-II (BDI-II) scores >/=14 and a diagnosis of MDD (using DSM-IV criteria) were randomized to either a low dose group (LDG) or high dose group (HDG) and received a 12-week manualized intervention. The …