Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Inverse Probability of Treatment Weighted (IPTW) Estimator; Causal Models; Marginal Structural Model (MSM) (1)
- Machine-Learning Algorithm; Environmental Risk Factors (1)
- Nested case control sampling; causal effect; counterfactual; double robust estimation; estimating function; locally efficient estimation; targeted maximum likelihood estimation (1)
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Causal Inference In Epidemiological Studies With Strong Confounding, Kelly L. Moore, Romain S. Neugebauer, Mark J. Van Der Laan, Ira B. Tager
Causal Inference In Epidemiological Studies With Strong Confounding, Kelly L. Moore, Romain S. Neugebauer, Mark J. Van Der Laan, Ira B. Tager
U.C. Berkeley Division of Biostatistics Working Paper Series
One of the identifiabilty assumptions of causal effects defined by marginal structural model (MSM) parameters is the experimental treatment assignment (ETA) assumption. Practical violations of this assumption frequently occur in data analysis, when certain exposures are rarely observed within some strata of the population. The inverse probability of treatment weighted (IPTW) estimator is particularly sensitive to violations of this assumption, however, we demonstrate that this is a problem for all estimators of causal effects. This is due to the fact that the ETA assumption is about information (or lack thereof) in the data. A new class of causal models, causal …
Causal Inference For Nested Case-Control Studies Using Targeted Maximum Likelihood Estimation, Sherri Rose, Mark J. Van Der Laan
Causal Inference For Nested Case-Control Studies Using Targeted Maximum Likelihood Estimation, Sherri Rose, Mark J. Van Der Laan
U.C. Berkeley Division of Biostatistics Working Paper Series
A nested case-control study is conducted within a well-defined cohort arising out of a population of interest. This design is often used in epidemiology to reduce the costs associated with collecting data on the full cohort; however, the case control sample within the cohort is a biased sample. Methods for analyzing case-control studies have largely focused on logistic regression models that provide conditional and not marginal causal estimates of the odds ratio. We previously developed a Case-Control Weighted Targeted Maximum Likelihood Estimation (TMLE) procedure for case-control study designs, which relies on the prevalence probability q0. We propose the use of …
A Machine-Learning Algorithm For Estimating And Ranking The Impact Of Environmental Risk Factors In Exploratory Epidemiological Studies, Jessica G. Young, Alan E. Hubbard, B Eskenazi, Nicholas P. Jewell
A Machine-Learning Algorithm For Estimating And Ranking The Impact Of Environmental Risk Factors In Exploratory Epidemiological Studies, Jessica G. Young, Alan E. Hubbard, B Eskenazi, Nicholas P. Jewell
U.C. Berkeley Division of Biostatistics Working Paper Series
No abstract provided.