Medicine and Health Sciences Commons^™

Altered Domain Functional Network Connectivity Strength And Randomness In Schizophrenia., Victor M Vergara, Eswar Damaraju, Jessica A Turner, Godfrey Pearlson, Aysenil Belger, Daniel H Mathalon, Steven G Potkin, Adrian Preda, Jatin G Vaidya, Theo G M Van Erp, Sarah C Mcewen, Vince D Calhoun

Articles, Abstracts, and Reports

Functional connectivity is one of the most widely used tools for investigating brain changes due to schizophrenia. Previous studies have identified abnormal functional connectivity in schizophrenia patients at the resting state brain network level. This study tests the existence of functional connectivity effects at whole brain and domain levels. Domain level refers to the integration of data from several brain networks grouped by their functional relationship. Data integration provides more consistent and accurate information compared to an individual brain network. This work considers two domain level measures: functional connectivity strength and randomness. The first measure is simply an average of …

Trends In Opioid Use In Pediatric Patients In Us Emergency Departments From 2006 To 2015, Daniel M. Tomaszewski, Cody Arbuckle, Sun Yang, Erik J. Linstead

Pharmacy Faculty Articles and Research

Importance The use of opioids to treat pain in pediatric patients has been viewed as necessary; however, this practice has raised concerns regarding opioid abuse and the effects of opioid use. To effectively adjust policy regarding opioids in the pediatric population, prescribing patterns must be better understood.

Objective To evaluate opioid prescribing patterns in US pediatric patients and factors associated with opioid prescribing.

Design, Setting, and Participants This cross-sectional study used publicly available data from the National Hospital Ambulatory Medical Care Survey from January 1, 2006, to December 31, 2015. Analysis included the use of bivariate and multivariate models to …

Syndemics Of Severity And Frequency Of Elder Abuse: A Cross-Sectional Study In Mexican Older Females, Mireya Vilar-Compte, Pablo Gaitán-Rossi

Department of Public Health Scholarship and Creative Works

Background: Elder abuse is a common phenomenon with important effects on the health and well-being of older adults. There are important gaps in elder abuse measurement, as it is usually reported as the absence or presence of elder abuse, disregarding its severity and frequency.

Objectives: Identify different ways of measuring severity and frequency of elder abuse and assess whether different experiences of severity and frequency suggest syndemic relationships.

Methods: Through a sample of 534 non-institutionalized Mexican older women, we assessed how severity (i.e., number of abusive experiences and number of types of abuses) and frequency (i.e., if abusive experiences had …

Access To Veterinary Care: Barriers, Current Practices, And Public Policy, Access To Veterinary Care Coalition

Faculty Publications and Other Works -- Small Animal Clinical Sciences

Pets have become an integral part of our families with over 80% of pet owners reporting that they consider their pets to be a member of their family. An estimated 29 million dogs and cats live in families that participate in the Supplemental Nutrition Assistance Program. There are also middle-class families that live paycheck to paycheck, with limited funds for veterinary care. These families deserve the companionship of pets to enjoy the mental, physical, and emotional benefits that come from this human-animal bond.

Through a grant from Maddie’s Fund®, the Access to Veterinary Care Coalition (AVCC) commissioned a national …

Art In The Stages Of Suffering And Death, Joanna Aramini

Visual Arts Department Student Scholarship

There has always been a strong link between art and the study of science and medicine, and one of the most iconic images of suffering and death in history to date is Christ suffering on the cross. In this thesis, I examine if and how art can make it possible to transcend human pain and overcome suffering, especially in our modern society where pain is seen as something we cannot deal with, and where we look to medicine and prescriptions to diminish it. I argue that art in the states of suffering and death, closely examining Michelangelo’s La Pieta and …

Practice And Lived Experience Of Menstrual Exiles (Chhaupadi) Among Adolescent Girls In Far Western Nepal. December 2018, Prabisha Amatya, Saruna Ghimire, Karen E. Callahan, Binaya Kumar Baral, Krishna C. Poudel

Public Health Faculty Publications

Background: Menstrual exile, also known as Chhaupadi, is a tradition of “untouchability” in far-western Nepal. Forbidden from touching other people and objects, women and girls are required to live away from the community, typically in a livestock shed, during menstruation. We assessed the lived experiences of Chhaupadi among Nepalese adolescent girls in the far-western Achham district of Nepal, observed the safety and sanitation of their living spaces during Chhaupadi, and assessed the perceptions of local adult stakeholders towards the practice of Chhaupadi. Methods: We collected data from 107 adolescent girls using a self-administered survey in two local schools in Achham. …

Mental Health Problems Of The Youngest Generation Of American Veterans (Problemy Zdrowia Psychicznego Najmłodszego Pokolenia Weteranów Amerykańskich), Jaroslaw Richard Romaniuk

Faculty Scholarship

Wartime activities determine the threats to a soldier’s life and health. To prepare soldiers for a new forms of warfare, one should know the challenges the soldier faces in the midst of battle and after returning home. From 2001 to 2015, 1.2 million American soldiers returning from Iraq and Afghanistan used the health care services of the Department of Veterans’ Affairs. An analysis of the resulting medical interventions makes possible a long term evaluation of the effects of war, some of which appear only after the soldier returns to civilian life. This study analyzes the research on the mental health …

Age-Tastic! An Evaluation Of An Evidence-Based Intervention For Older Adults, Manoj Pardasani, Jackie Berman, Mebane Powell

Publications and Research

Background: Raising awareness of holistic health and safety among older adults is critical to enhancing their wellbeing in many cases, improving health outcomes and motivating positive behavioral changes. Age-Tastic! is a comprehensive health and safety promotion intervention that uses the concept of a competitive board game to entice older adults to participate and stay engaged.

Objective: The purpose of this study was to evaluate the impact of Age-Tastic! on the level of awareness, health literacy, self-efficacy and positive behavioral change among the participants.

Methods: A randomized control trial was conducted with 98 older adults assigned to an experimental and control …

Healthy Food Options At Dollar Discount Stores Are Equivalent In Quality And Lower In Price Compared To Grocery Stores: An Examination In Las Vegas, Nv, Courtney Coughenour, Timothy J. Bungum, M. Nikki Regalado

Public Health Faculty Publications

Food deserts indicate limited access to and affordability of healthy foods. One potential mediator is the availability of healthy food in non-traditional outlets such as dollar-discount stores, stores selling produce at the fixed $1 price. The purpose of this study was to compare availability, quality, price differences in ‘healthier’ versus ‘regular’ food choices, price per each food item, and summary score in dollar-discount stores to grocery stores in Las Vegas using the NEMS-S; a protocol consisting of three subscores—availability, quality, price of healthier versus regular food, and a summary score. [...] see article for full abstract

Clinician Identified Barriers To Treatment For Individuals In Appalachia With Opioid Use Disorder Following Release From Prison: A Social Ecological Approach, Amanda M. Bunting, Carrie B. Oser, Michele Staton, Katherine S. Eddens, Hannah K. Knudsen

Sociology Faculty Publications

Background: The non-medical use of opioids has reached epidemic levels nationwide, and rural areas have been particularly affected by increasing rates of overdose mortality as well as increases in the prison population. Individuals with opioid use disorder (OUD) are at increased risk for relapse and overdose upon reentry to the community due to decreased tolerance during incarceration. It is crucial to identify barriers to substance use disorder treatment post-release from prison because treatment can be particularly difficult to access in resource-limited rural Appalachia.

Methods: A social ecological framework was utilized to examine barriers to community-based substance use treatment among individuals …

From The Household To Watershed: A Cross-Scale Analysis Of Residential Intention To Adopt Green Stormwater Infrastructure, Sarah Coleman, Stephanie Hurley, Donna Rizzo, Christopher Koliba, Asim Zia

College of Engineering and Mathematical Sciences Faculty Publications

Improved stormwater management for the protection of water resources requires bottom-up stewardship from landowners, including adoption of Green Stormwater Infrastructure (GSI). We use a statewide survey of Vermont paired with a cross-scale and spatial analysis to evaluate the influence of interacting spatial, social, and physical factors on residential intention to adopt GSI across a complex social-ecological landscape. Specifically, we focus on how three GSI practices, (“rain garden (bio retention),” “infiltration trenches,” and “actively divert roof runoff to a rain barrel/lawn/garden instead of the street/sewer”) vary with barriers to adoption, and household attributes across stormwater contexts from the household to watershed …

The Natural Capital Accounting Opportunity: Let’S Really Do The Numbers, James W. Boyd, Kenneth J. Bagstad, Jane Carter Ingram, Carl D. Shapiro, Jeffery E. Adkins, C. Frank Casey, Clifford S. Duke, Pierre D. Glynn, Erica Goldman

Rubenstein School of Environment and Natural Resources Faculty Publications

No abstract provided.

Ecology And Genomics Of An Important Crop Wild Relative As A Prelude To Agricultural Innovation, Eric J.B. Von Wettberg, Peter L. Chang, Fatma Başdemir, Noelia Carrasquila-Garcia, Lijalem Balcha Korbu, Susan M. Moenga, Gashaw Bedada, Alex Greenlon, Ken S. Moriuchi, Vasantika Singh, Matilde A. Cordeiro, Nina V. Noujdina, Kassaye Negash Dinegde, Syed Gul Abbas Shah Sani, Tsegaye Getahun, Lisa Vance, Emily Bergmann, Donna Lindsay, Bullo Erena Mamo, Emily J. Warschefsky, Emmanuel Dacosta-Calheiros, Edward Marques, Mustafa Abdullah Yilmaz, Ahmet Cakmak, Janna Rose, Andrew Migneault, Christopher P. Krieg, Sevgi Saylak, Hamdi Temel, Maren L. Friesen, Eleanor Siler

College of Agriculture and Life Sciences Faculty Publications

Domesticated species are impacted in unintended ways during domestication and breeding. Changes in the nature and intensity of selection impart genetic drift, reduce diversity, and increase the frequency of deleterious alleles. Such outcomes constrain our ability to expand the cultivation of crops into environments that differ from those under which domestication occurred. We address this need in chickpea, an important pulse legume, by harnessing the diversity of wild crop relatives. We document an extreme domestication-related genetic bottleneck and decipher the genetic history of wild populations. We provide evidence of ancestral adaptations for seed coat color crypsis, estimate the impact of …

From The Household To Watershed: A Cross-Scale Analysis Of Residential Intention To Adopt Green Stormwater Infrastructure, Sarah Coleman, Stephanie Hurley, Donna Rizzo, Christopher Koliba, Asim Zia

College of Agriculture and Life Sciences Faculty Publications

Improved stormwater management for the protection of water resources requires bottom-up stewardship from landowners, including adoption of Green Stormwater Infrastructure (GSI). We use a statewide survey of Vermont paired with a cross-scale and spatial analysis to evaluate the influence of interacting spatial, social, and physical factors on residential intention to adopt GSI across a complex social-ecological landscape. Specifically, we focus on how three GSI practices, (“rain garden (bio retention),” “infiltration trenches,” and “actively divert roof runoff to a rain barrel/lawn/garden instead of the street/sewer”) vary with barriers to adoption, and household attributes across stormwater contexts from the household to watershed …

"Integrated Science 3002a: Big Bike Giveaway: Changing London's Environment, Health, And Economy One Bike At A Time", Jermiah Joseph, Katelyn Melo, Devanshi Shukla, Tony Nguyen, Katherine Teeter

Community Engaged Learning Final Projects

There are significant benefits that manifest when an individual chooses to ride a bicycle as their primary mode of transportation. To investigate these benefits, the environmental, health, economic, and social impacts of biking were evaluated through research and data analyses. This revealed that numerous advantages can be obtained at an individual and local scale through citizens choosing to adopt a biking lifestyle. However, it was found that many Londoners are deterred from biking due to poor biking infrastructure. This paper calls into question the current cycling framework in London and it’s limitations on achieving the numerous benefits that biking offers. …

Global State And Potential Scope Of Investments In Watershed Services For Large Cities, Chelsie L. Romulo, Stephen Posner, Stella Cousins, Jenn Hoyle Fair, Drew E. Bennett, Heidi Huber-Stearns, Ryan C. Richards, Robert I. Mcdonald

Peer-Reviewed Studies

Investments in watershed services (IWS) programs, in which downstream water users pay upstream watershed service suppliers for actions that protect drinking water, are increasing in number and scope. IWS programs represent over $170 million of investment in over 4.3 million ha of watersheds, providing water to over 230 million people. It is not yet fully clear what factors contribute to the establishment and sustainability of IWS. We conducted a representative global analysis of 416 of the world’s largest cities, including 59 (14%) with IWS programs. Using random forest ensemble learning methods, we evaluated the relative importance of social and ecological …

Variables Predicting The Severity Of A Mass Shooting: The Connection To White Supremacy, Sarina Resnick

Honors Projects in History and Social Sciences

Since mass shootings have become increasingly relevant in today’s society, the subject of what makes a mass shooting deadly has become more and more popular. This project focuses on how selected variables correlate with the severity of a mass shooting, and especially focuses on the impact of white supremacy ideology. Theoretically, a shooter imbued with this ideology will likely be more violent, thus causing a higher victim count (injuries + deaths). The other variables included in the model are: the use of a long gun, the use of multiple guns, the use of semi-automatic guns, mental illness, and shooter suicide. …

From The Household To Watershed: A Cross-Scale Analysis Of Residential Intention To Adopt Green Stormwater Infrastructure, Sarah Coleman, Stephanie Hurley, Donna Rizzo, Christopher Koliba, Asim Zia

College of Agriculture and Life Sciences Faculty Publications

Improved stormwater management for the protection of water resources requires bottom-up stewardship from landowners, including adoption of Green Stormwater Infrastructure (GSI). We use a statewide survey of Vermont paired with a cross-scale and spatial analysis to evaluate the influence of interacting spatial, social, and physical factors on residential intention to adopt GSI across a complex social-ecological landscape. Specifically, we focus on how three GSI practices, (“rain garden (bio retention),” “infiltration trenches,” and “actively divert roof runoff to a rain barrel/lawn/garden instead of the street/sewer”) vary with barriers to adoption, and household attributes across stormwater contexts from the household to watershed …

Law Library Blog (December 2018) : Legal Beagle's Blog Archive, Roger Williams University School Of Law

Law Library Newsletters/Blog

No abstract provided.

Similarity Of Introduced Plant Species To Native Ones Facilitates Naturalization, But Differences Enhance Invasion Success, Jan Divíšek, Milan Chytrý, Brian Beckage, Nicholas J. Gotelli, Zdeňka Lososová, Petr Pyšek, David M. Richardson, Jane Molofsky

College of Arts and Sciences Faculty Publications

The search for traits associated with plant invasiveness has yielded contradictory results, in part because most previous studies have failed to recognize that different traits are important at different stages along the introduction–naturalization–invasion continuum. Here we show that across six different habitat types in temperate Central Europe, naturalized non-invasive species are functionally similar to native species occurring in the same habitat type, but invasive species are different as they occupy the edge of the plant functional trait space represented in each habitat. This pattern was driven mainly by the greater average height of invasive species. These results suggest that the …

Measuring Novel Antecedents Of Mental Illness: The Questionnaire Of Unpredictability In Childhood, Laura M. Glynn, Hal S. Stern, Mariann A. Howland, Victoria B. Risbrough, Dewleen G. Baker, Caroline M. Nievergelt, Tallie Z. Baram, Elysia P. Davis

Psychology Faculty Articles and Research

Increasing evidence indicates that, in addition to poverty, maternal depression, and other well-established factors, unpredictability of maternal and environmental signals early in life influences trajectories of brain development, determining risk for subsequent mental illness. However, whereas most risk factors for later vulnerability to mental illness are readily measured using existing, clinically available tools, there are no similar measures for assessing early-life unpredictability. Here we validate the Questionnaire of Unpredictability in Childhood (QUIC) and examine its associations with mental health in the context of other indicators of childhood adversity (e.g., traumatic life events, socioeconomic status, and parenting quality). The QUIC was …

Blocking Drug Activation As A Therapeutic Strategy To Attenuate Acute Toxicity And Physiological Effects Of Heroin, Ting Zhang, Xirong Zheng, Kyungbo Kim, Fang Zheng, Chang-Guo Zhan

Molecular Modeling and Biopharmaceutical Center Faculty Publications

Heroin is a growing national crisis in America. There is an increasing frequency of heroin overdoses. All of the currently used therapeutic approaches to treatment of heroin abuse and other opioid drugs of abuse focus on antagonizing a brain receptor (particularly µ-opiate receptors). However, it has been known that the therapeutic use of certain µ-opiate receptor antagonist may actually increase heroin overdose. Once overdosed, heroin addicts may continue to get overdosed again and again until fatal. Here we report our design and validation of a novel therapeutic strategy targeting heroin activation based on our analysis of the chemical transformation and …

Honoring Veterans Means Funding Suicide Prevention, Brendan Cushing-Daniels, Christopher R. Fee

Economics Faculty Publications

Many Americans may not know that it was Dwight D. Eisenhower who in 1954 issued the official proclamation celebrating the service of all veterans by designating Nov. 11, formerly known as Armistice Day, in honor of our vets. Eisenhower, of course, was supreme commander of Allied Forces in Europe during World War II and commander in chief as the 34th president of the United States.

In Ike’s words, “on that day let us solemnly remember the sacrifices of all those who fought so valiantly, on the seas, in the air, and on foreign shores, to preserve our heritage of freedom, …

Functional Brain Activation Changes Associated With Practice In Delaying Smoking Among Moderate To Heavy Smokers: Study Protocol And Rationale Of A Randomized Trial (Cope)., Andrew T. Fox, Delwyn Catley, Kimber P. Richter, Edward F. Ellerbeck, Morgan G. Brucks, Vlad B. Papa, Laura E. Martin

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Most smokers struggle to overcome tobacco addiction. Neuroscientific models of addiction emphasize the importance of brain regions associated with cognitive control and reward to understand the cycle of addiction and relapse. During an attempt at abstinence, the cognitive control system appears to be underpowered to override the heightened reward system of the addicted brain. Thus, one neural target for treatment is to strengthen the cognitive control system. It may be possible to improve the functioning of the cognitive control system via deliberate practice.

METHODS/DESIGN: This study will determine the effects of practicing delaying smoking on brain and behavioral measures …

The Life She Deserves: Medical Marijuana In The United States, John Hudak, George Burroughs, Maritza Bermudez

Brookings Scholar Lecture Series

Brookings Mountain West offered an event titled, "The Life She Deserves: Medical Marijuana in the United States on Monday, November 5, 2018. This event featured a viewing of the film, and was followed by a panel discussion with John Hudak, George Burroughs, and Maritza Bermudez. “The Life She Deserves” is an intimate portrait of Jennifer Collins and her family’s struggle to find a treatment to control her debilitating epilepsy. Because her legal pharmaceutical treatments cause severe side effects, Jennifer and her mother move across the country to access medical marijuana. The therapy provides Jennifer and her family with the relief …

Improving Mental Health And Substance Abuse Treatment In Juvenile Detention Facilities, Harvard Law School Mississippi Delta Project

Delta Directions: Publications

Mental health and substance abuse treatment services are an essential component of a well-functioning rehabilitative juvenile justice system. These services are especially important in juvenile detention facilities, which contain a disproportionate number of juveniles suffering from mental illness due to the association between such issues and delinquency and the relative lack of services in the community.

Ensuring Compliance From 35,000 Feet: Accountability And Trade-Offs In Aviation Safety Regulatory Networks, Russell W. Mills, Christopher J. Koliba, Dorit Rubinstein Reiss

College of Agriculture and Life Sciences Faculty Publications

A puzzle that faces public administrators within regulatory networks is how to balance the need for public or democratic accountability with increasing demands from interest groups and elected officials to utilize the expertise of the private sector in developing process-oriented programs that ensure compliance. This article builds upon the network governance accountability framework developed by Koliba, Mills, and Zia to explore the dominant accountability frames and the accountability trade-offs that shape the process-oriented regulatory regime used by the Federal Aviation Administration (FAA) to oversee and regulate air carriers in the United States.

Development And Testing Of An Assessment Of Youth/Young Adult Voice In Agency-Level Advising And Decision Making, Janet S. Walker, Brie Masselli, Jennifer E. Blakeslee, Caitlin Baird, Kristin Thorp

School of Social Work Faculty Publications and Presentations

There is a range of stakeholder benefits when youth- and young adult-serving agencies include service recipient “voice” in advising and decision making regarding agency policies and programming. Yet many agency stakeholders lack awareness of strategic best practices to ensure the consistent and meaningful participation of young people in decision-making processes, and few tools exist to evaluate agency efforts. This paper describes the development and validation of the Youth/Young Adult Voice at the Agency Level (Y-VAL), an assessment of the extent to which agencies have implemented best practices for supporting meaningful participation. The Y-VAL is intended for research purposes, as well …

Peer-Delivered Harm Reduction And Recovery Support Services: Initial Evaluation From A Hybrid Recovery Community Drop-In Center And Syringe Exchange Program, Robert D. Ashford, Brenda Curtis, Austin M. Brown

Faculty Articles

Background: Recovery from substance use disorder (SUD) is often considered at odds with harm reduction strategies. More recently, harm reduction has been categorized as both a pathway to recovery and a series of services to reduce the harmful consequences of substance use. Peer recovery support services (PRSS) are effective in improving SUD outcomes, as well as improving the engagement and effectiveness of harm reduction programs. Methods: This study provides an initial evaluation of a hybrid recovery community organization providing PRSS as well as peer-based harm reduction services via a syringe exchange program. Administrative data collected during normal operations of the …

Spatio-Temporal Distribution Of Negative Emotions In New York City After A Natural Disaster As Seen In Social Media, Oliver Gruebner, Sarah R. Lowe, Martin Sykora, Ketan Shankardass, Sv Subramanian, Sandro Galea

Department of Psychology Faculty Scholarship and Creative Works

Disasters have substantial consequences for population mental health. We used Twitter to (1) extract negative emotions indicating discomfort in New York City (NYC) before, during, and after Superstorm Sandy in 2012. We further aimed to (2) identify whether pre- or peri-disaster discomfort were associated with peri- or post-disaster discomfort, respectively, and to (3) assess geographic variation in discomfort across NYC census tracts over time. Our sample consisted of 1,018,140 geo-located tweets that were analyzed with an advanced sentiment analysis called ”Extracting the Meaning Of Terse Information in a Visualization of Emotion” (EMOTIVE). We calculated discomfort rates for 2137 NYC census …