Medicine and Health Sciences Commons^™

Letter To The Editor (Human Immunodeficiency Virus In Costa Rica), Mark W. Oberle, Charles A. Schable, Mary Guinan, Luis Rosero

Public Health Faculty Publications

Recent reports of 12 confirmed cases of acquired immunodeficiency syndrome (AIDS) in Costa Rica have generated interest in the extent of spread of human T-lymphotropic virus type III/LAV (HTLV-III) in Latin America (1). To date, all cases of AIDS in Costa Rica have occurred in members of previously identified, high-risk groups, chiefly hemophiliacs. To examine the possibility of heterosexual transmission in Costa Rica, we utilized sera collected in a population-based case-control study of cervical cancer, conducted by the Costa Rican Demographic Association and other institution.

Fine-Structure Analysis Of The Processing And Polyadenylation Region Of The Herpes Simplex Virus Type 1 Thymidine Kinase Gene By Using Linker Scanning, Internal Deletion, And Insertion Mutations., Fang Zhang, Roger M. Denome, Charles N. Cole

Dartmouth Scholarship

Most eucaryotic mRNAs are polyadenylated. In higher eucaryotes, the sequence AATAAA is located 7 to 30 base pairs (bp) upstream from the site of processing and polyadenylation and is a critical part of the signal for processing and polyadenylation. Efficient cleavage and polyadenylation also require sequences downstream of polyadenylation sites. The herpes simplex virus type 1 thymidine kinase (tk) gene contains two copies of the AATAAA hexanucleotide and a GT box (18 of 19 consecutive residues are G or T) previously shown to be required for efficient processing and polyadenylation of tk mRNA (C. N. Cole and T. P. Stacy, …

Relationship Between Dietary Intake And Reproductive Hormones In Premenopausal Vegetarian And Nonvegetarian Seventh-Day Adventist Women, Joan M. Spuehler

Loma Linda University Electronic Theses, Dissertations & Projects

There is evidence that specific nutrients may modify hormonal balance and contribute to breast cancer etiology. To investigate the relationship between dietary nutrients and plasma reproductive hormones and to determine hormone-nutrient interrelationships, we measured plasma estrogens, androgens. progesterone and prolactin levels in 10 premenopausal Seventh-day Adventist (SDA) vegetarian and 10 premenopausal SDA nonvegetarian women. Over three days in each of three consecutive months. diet records and fasting midluteal blood samples were collected. The nonvegetarians consumed significantly more protein, total and saturated fats, oleic and linoleic acids, and cholesterol than did the vegetarians. Hormonal status of the two groups did not …

The Relationship Between Meat Consumption And The Biological Determinants Of Cardiovascular Disease Risk, Fred E. Kollwitz

Loma Linda University Electronic Theses, Dissertations & Projects

Fasting blood samples were collected from 26 omnivore and 27 vegetarian men (35-60 years of age), who were not taking any medications and by self-assessment were in good health. The following analyses were done: glucose (Glu), glycohemoglobin (HBA1), total serum cholesterol (chole), high density lipoprotein-cholesterol (HDD, low density lipoprotein (LDL), very low density lipoprotein (VLDL), platelet factor four (PF4), and beta-thromboglobulin (BTG). In addition, the blood pressure (BP) was determined.

The systolic (p<0.001) and diastolic BP (p=0.016) were lower in the vegetarian subjects than in the omnivores. The serum total cholesterol levels were also lower in the vegetarian subjects compared to the omnivores (p<0.05). There was no significant difference in Glu, HBA1, LDL, VLDL, HDL, PF4, and BTG levels between the two groups.

Absence Of A Structural Basis For Intracellular Recognition And Differential Localization Of Nuclear And Plasma Membrane-Associated Forms Of Simian Virus 40 Large Tumor Antigen., Donald L. Jarvis, Charles N. Cole, Janet S. Butel

Dartmouth Scholarship

The simian virus 40 large tumor antigen (T-ag) is found in both the nuclei (nT-ag) and plasma membranes (mT-ag) of simian virus 40-infected or -transformed cells. It is not known how newly synthesized T-ag molecules are recognized, sorted, and transported to their ultimate subcellular destinations. One possibility is that these events depend upon structural differences between nT-ag and mT-ag. To test this possibility, we compared the structures of nT-ag and mT-ag from simian virus 40-infected cells. No differences between the two forms of T-ag were detected by migration in polyacrylamide gels, by Staphylococcus aureus V8 partial proteolytic mapping of methionine- …

Preventing Lupinosis With Phomopsis-Resistant Lupins, Jeremy G. Allen, W. A. Cowling

Journal of the Department of Agriculture, Western Australia, Series 4

Lupinosis is one of the major livestock siseases in Western Australia. It is caused by stock eating toxins produced by the fungus Phomopsis leptostromiformis which colonises the stems of dead lupin plants.

In 975, the Department of Agriculture started a breeding programme to develop Phompsis-resistant lupins to overcome or control lupinosis. In the previous issue of this Journal the results of small plot evaluations of new lines of Phompsis-resistant lupins developed in this programme were reported. This article describes the first trial involving grazing of Phompsis-resistant lupins.

Annual Ryegrass Toxicity Research Update, A G P Brown, P. Vogal

Journal of the Department of Agriculture, Western Australia, Series 4

Annual ryegrass toxicity (ARGT) is a complex disease that kills sheep and cattle grazing pastures which contain infected ryegrass. The disease results when a nematode (Anguina agrostis) and a batcerium (Corynebacterium sp.) invade annual ryegrass and cause the seed heads to become toxic as the grass dries off.

The bacterium produces a complex toxin of 18 glycolipid compounds or corynetoxins which have been found to be virtually identical to the antibiotic tunicamycin.

Parasite Community Structure In Summer Flounder: Paralichthys Dentatus (Linnaeus), Of The Chesapeake Bay, Maura E. Jansen

Dissertations, Theses, and Masters Projects

No abstract provided.