Open Access. Powered by Scholars. Published by Universities.®
Research Methods in Life Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Animal Experimentation and Research (5)
- Cell and Developmental Biology (4)
- Animal Sciences (3)
- Biochemistry, Biophysics, and Structural Biology (3)
- Biodiversity (3)
-
- Engineering (3)
- Pharmacology, Toxicology and Environmental Health (3)
- Biochemistry (2)
- Bioinformatics (2)
- Biology (2)
- Cancer Biology (2)
- Cell Biology (2)
- Developmental Biology (2)
- Ecology and Evolutionary Biology (2)
- Genetics and Genomics (2)
- Medicine and Health Sciences (2)
- Microbiology (2)
- Molecular Biology (2)
- Other Animal Sciences (2)
- Terrestrial and Aquatic Ecology (2)
- Animal Studies (1)
- Applied Mathematics (1)
- Applied Statistics (1)
- Biomaterials (1)
- Biomedical Engineering and Bioengineering (1)
- Biostatistics (1)
- Chemical Engineering (1)
- Computational Biology (1)
- Keyword
-
- Antimicrobials (1)
- Bacterial Physiology (1)
- Biomaterials (1)
- Breast cancer (1)
- Cancer (1)
-
- Carbon Use Efficiency (1)
- Carnivore community (1)
- Cichlids (1)
- Cobblestone lissencephaly (1)
- Colon cancer (1)
- Comparative Genomics (1)
- Conjugated linoleic acid (1)
- Curriculum (1)
- Development (1)
- Drosophila melanogaster (1)
- Ecology (1)
- Endoplasmic reticulum (1)
- Energy metabolism (1)
- Epigallocatechin gallate (1)
- Evolution (1)
- Global development (1)
- Gut microbiome (1)
- Immune Modulation (1)
- Inflammatory bowel disease (1)
- Kasanka National Park Zambia and Banni Grasslands Kutch India (1)
- Low and middle income countries (1)
- Macroecology and community ecology (1)
- Mammal monitoring and conservation (1)
- Mammography (1)
- Markov decision process (1)
- Publication Type
Articles 1 - 9 of 9
Full-Text Articles in Research Methods in Life Sciences
Monitoring Mammals At Multiple Scales: Case Studies From Carnivore Communities, Kadambari Devarajan
Monitoring Mammals At Multiple Scales: Case Studies From Carnivore Communities, Kadambari Devarajan
Doctoral Dissertations
Carnivores are distributed widely and threatened by habitat loss, poaching, climate change, and disease. They are considered integral to ecosystem function through their direct and indirect interactions with species at different trophic levels. Given the importance of carnivores, it is of high conservation priority to understand the processes driving carnivore assemblages in different systems. It is thus essential to determine the abiotic and biotic drivers of carnivore community composition at different spatial scales and address the following questions: (i) What factors influence carnivore community composition and diversity? (ii) How do the factors influencing carnivore communities vary across spatial and temporal …
Elucidating Mechanisms Of Metastasis With Implantable Biomaterial Niches, Ryan Adam Carpenter
Elucidating Mechanisms Of Metastasis With Implantable Biomaterial Niches, Ryan Adam Carpenter
Doctoral Dissertations
Metastasis is the leading cause of cancer related deaths, yet it remains the most poorly understood aspect of tumor biology. This can be attributed to the lack of relevant experimental models that can recapitulate the complex and lengthy progression of metastatic relapse observed in patients. Mouse models have been widely used to study cancer, however they are critically limited to study metastasis. Most models generate aggressive metastases in the lung without the use of unique cell lines or specialized injection techniques. This limits the ability to study disseminated tumor cells (DTCs) in other relevant metastasis prone tissues. Prolonged observation of …
Tpr-Containing Proteins Control Protein Organization And Homeostasis For The Endoplasmic Reticulum, Jill Bradley-Graham
Tpr-Containing Proteins Control Protein Organization And Homeostasis For The Endoplasmic Reticulum, Jill Bradley-Graham
Doctoral Dissertations
The endoplasmic reticulum (ER) is a complex, multifunctional organelle comprised of a continuous membrane and lumen that is organized into several functional regions. It plays various roles including protein translocation, folding, quality control, secretion, calcium signaling, and lipid biogenesis. Cellular protein homeostasis is maintained by a complicated chaperone network, and the largest functional family within this network consists of proteins containing tetratricopeptide repeats (TPRs). TPRs are well-studied structural motifs that mediate intermolecular protein-protein interactions, supporting interactions with a wide range of ligands or substrates. Nine TPR-containing proteins have been shown to localize to the ER and control protein organization and …
Environmental Risk Factors For Inflammatory Bowel Disease: Triclosan And Other Consumer Antimicrobials, Katherine Z. Sanidad
Environmental Risk Factors For Inflammatory Bowel Disease: Triclosan And Other Consumer Antimicrobials, Katherine Z. Sanidad
Doctoral Dissertations
Inflammatory bowel disease (IBD) has become a serious health problem since the incidence and prevalence of IBD has dramatically increased throughout the world. There is evidence that environmental factors are primarily responsible for the increase of IBD, therefore, it is important to identify novel environmental risk factors to reduce the risk of IBD and its associated diseases. Antimicrobials used in consumer products might serve as environmental risk factors for IBD and its associated diseases. Triclosan (TCS), triclocarban (TCC), benzalkonium chloride (BAC), benzethonium chloride (BET), and chloroxylenol (PCMX) are widely used antimicrobial ingredients in consumer products and are ubiquitous contaminants in …
Drivers And Consequences Of Carbon Use Efficiency - And Its Measurement In Soil, Grace Pold
Drivers And Consequences Of Carbon Use Efficiency - And Its Measurement In Soil, Grace Pold
Doctoral Dissertations
Soils serve as massive carbon sinks, but their ability to continue this ecological service is contingent on how the resident soil microbial community will respond to the ongoing climate crisis. One key dimension of the microbial response to warming is its carbon use efficiency (CUE), or the fraction of carbon taken up by an organism which is allocated to growth rather than respiration. However, the scientific community is still in the early stages of understanding the drivers, consequences - and even accurate measurements of - CUE. In this dissertation, I first quantified the variability of CUE and its responsiveness to …
Patterns Of Morphological Plasticity In Metriaclima Zebra And Danio Rerio Suggest Differently Canalized Phenotypes Due To Form-Function Relationships, Dylan Jockel
Masters Theses
In order to ascertain the degree of compatibility in developmental restructuring and behavioral plasticity between two fish species frequently made subject of laboratory research (Metriaclima zebra & Danio rerio), alternative trophic niche exposure experiments utilizing novel three-prong feeding treatments were conducted to obtain morphometric data, which demonstrated both species do bear some degree of plasticity. The results are somewhat complicated by differences in locality of detectable restructuring, which may be due to disparity in the form-function relationship for each species’ lineage. Each is notable in the manner of respective species’ jaw protrusion, as it is driven by anterior …
Markov Decision Process Approach To Strategize National Breast Cancer Screening Policy In Data-Limited Settings, Vijeta Deshpande
Markov Decision Process Approach To Strategize National Breast Cancer Screening Policy In Data-Limited Settings, Vijeta Deshpande
Masters Theses
Early diagnosis is a promising strategy to reduce premature mortalities and for optimal use of resources. But the absence of mathematical models specific to the data settings in LMIC’s impedes the construction of economic analysis necessary for decision-makers in the development of cancer control programs. This thesis presents a new methodology for parameterizing the natural history model of breast cancer based on data availabilities in low and middle income countries, and formulation of a control optimization problem to find the optimal screening schedule for mammography screening, solved using dynamic programming. As harms and benefits are known to increase with the …
Applications Of Drosophila Melanogaster In Food Science Research, Phoebe Beverly Chen
Applications Of Drosophila Melanogaster In Food Science Research, Phoebe Beverly Chen
Doctoral Dissertations
Drosophila melanogaster is a versatile model organism that provides several unique features, such as highly conserved disease pathways with humans as well as availability of environmental and genetic manipulations. Meanwhile, there is increasing interest in the potential role of bioactive food components, epigallocatechin gallate (EGCG) and conjugated linoleic acid (CLA), in metabolic research. However, there is limited knowledge on the sex-dependent effects of EGCG and CLA on energy metabolism. In this study, Drosophila melanogaster was used to investigate the sex-dependent effects of EGCG and CLA with respect to energy metabolism, including body fat, locomotion, and their key metabolic regulators. We …
Syllabus: Drinking Water, Sanitation, And Global Development, Emily Kumpel
Syllabus: Drinking Water, Sanitation, And Global Development, Emily Kumpel
Sustainability Education Resources
Within the past three decades, more than 2.6 billion people have gained access to an improved water source and 2.1 billion have gained access to an improved sanitation facility. However, improved does not always mean people have safe, reliable, accessible, or equitable water and sanitation services. Waterborne diseases continue to cause and estimated 500,000 deaths each year. What causes waterborne diseases, and what is the role of engineered systems in their spread or prevention? How can we evaluate interventions to improve health and well-being? How can research address these challenges?