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Full-Text Articles in Physiology
Effects Of Muscle Cooling On Ampk And Protein Synthesis In Skeletal Muscle, Kyle Lyons, David Thomson, Pdbio
Effects Of Muscle Cooling On Ampk And Protein Synthesis In Skeletal Muscle, Kyle Lyons, David Thomson, Pdbio
Journal of Undergraduate Research
AMP-activated protein kinase (AMPK) is an intracellular protein that regulates many signaling responses including the mechanistic target of rapamycin (mTOR) pathway, which increases protein synthesis1. Recent research suggests that cold-water immersion of the leg activates AMPK in skeletal muscle. It is not known whether cold directly activates AMPK in skeletal muscle or if the aforementioned results are due to systemic or hormonal responses. Furthermore, the direct effect of cooling on protein synthesis-related signaling in skeletal muscle has not been established. If cooling affects the activation of AMPK, then it could also affect mTOR. Therefore, the purpose of this study was …
Regulation Of The Transcription Factor Creb In Skeletal Muscle After Exercise, David M. Thomson
Regulation Of The Transcription Factor Creb In Skeletal Muscle After Exercise, David M. Thomson
Journal of Undergraduate Research
My laboratory is running quite smoothly now. The students in the laboratory are proficient in performing experiments, obtaining data and interpreting it. My first undergraduate students have recently graduated, and I now have a nice array of experienced and newer inexperienced students, so the work is moving forward steadily, both in terms of productivity and of student training. I enjoy seeing students come into the lab with essentially no knowledge of laboratory techniques and the particular physiological topics that we study, and within a couple of months gaining enough knowledge to contribute to an intellectual discussion of the principles we …