Physiology Commons^™

Effects Of Balance Training On Spinal Reflexive Excitability Modulation, Corticospinal Excitability, And Balance Performance In Individuals With Chronic Ankle Instability, Sunghoon Chung

Rehabilitation Sciences Theses & Dissertations

Chronic ankle instability (CAI) is a neurophysiologic deficit resulting in diverse sensorimotor impairments. Following acute ankle sprains, pain, mechanical instability, and joint deafferentation reduce sensory input to the central nervous system (CNS). In response, the CNS sends altered motor signals to lower extremity muscles. These CNS changes contribute to various neuromuscular impairments in CAI patients, the most common of which is reduced balance performance. Specifically, CAI patients struggle to modulate spinal reflex excitability of the soleus muscle when progressing from simpler to more complex balance tasks. This overreliance on spinal reflexes results in inconsistent activation of the ankle stabilizing muscle. …

Dental Hygiene Students Reported Physiological Symptoms Associated With Wearing An N95 Respirator Mask, Peyton Shea Butler

Dental Hygiene Theses & Dissertations

Purpose: Physiological symptoms and comfort levels while wearing an N95 respiratory mask has not been examined with dental hygienists. The purpose of this study was to investigate dental hygiene students reported physiological symptoms and comfort perception while wearing an N95 respirator mask during patient care appointments. Methods: After IRB approval (IRB #1987754-2), a 16-item questionnaire was distributed through email to a convenience sample of 65 dental hygiene students. Questions assessed respiratory, dermatologic, cardiac, mask mouth and general physiological symptoms, as well as comfort levels. Additionally, participants were asked to respond to demographic questions and one open ended question inquiring about …

The Impact Of Muscular Strength On Cardiovascular Disease Risk Factors, Joel Ernest Harden

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to determine the associations between isokinetic leg muscular strength and cardiovascular disease (CVD) risk factor characterizations in Americans aged 50 and older. Using a publicly available dataset from the National Health and Nutrition Examination Survey (NHANES), a secondary analysis was conducted on participants (males ≥50 yrs; females ≥55 yrs; N=10,858) pooled from 1999 to 2002. CVD risk factors were determined using the American College of Sports Medicine (ACSM) cutoff values, with all nine ACSM risk factors analyzed. CVD risk factor characterization was determined by creating CVD risk factor profiles (i.e., the total number of …

Effect Of A 2-Week Relaxing Music Intervention On Anxiety, Stress, And Gut Symptoms In Aerobic Exercisers, Halie Marisa Maass

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to determine the impact of a two-week relaxing music intervention on stress, anxiety, and gastrointestinal (GI) symptoms in exercisers with at least mild anxiety and exercise-related GI symptoms. Block randomization was used to allocate 15 women and two men into control (n = 8) or intervention (n = 9) groups following a one-week baseline. During the baseline period, participants recorded details of their aerobic exercise sessions and discomfort with GI symptoms (nausea, regurgitation/reflux, stomach fullness, bloating, abdominal cramps, gas, the urge to defecate). Following randomization, both groups tracked these same details for two additional …

Lack Of Delayed-Type Hypersensitivity In Striped Bass (Morone Saxatilis), Jessica Shannon Miller

Biological Sciences Theses & Dissertations

Mycobacteriosis is a fatal disease in fishes caused by acid-fast bacteria in the genus Mycobacterium. This disease impacts aquaculture, aquariums, and wild fishes. Unfortunately, there are currently no non-lethal diagnostic tests for mycobacterial infection in fishes. Type IV delayed type hypersensitivity (DTH) responses in vivo and in vitro are currently used for the non-lethal detection of mycobacterial infections in humans and in animals; however, there is little information available on DTH responses in fishes. In this work, we examine in vivo DTH response in Striped Bass (Morone saxatilis), an important U.S. Eastern seaboard fish species, experimentally …

Effects Of Knee Sleeves On Knee Mechanics During Squats At Variable Depths, Alexandria A. Trypuc

Human Movement Studies & Special Education Theses & Dissertations

The squat is a functional, compound and multi-joint exercise that targets several muscles of the lower body and is widely used in both athletics and many exercise programs. This exercise has been the subject of many studies, comparing different squat variations and examining how external gear, such as squat suits and knee wraps impact the exercise. The aim of this study was to assess the effects of wearing neoprene knee sleeves on lower extremity kinematics, kinetics, and muscle activations during weighted back squats. Fifteen resistance trained men and women, aged 28±5 years, from the local fitness community and university campus …

Structure Of The Picornavirus Replication Platform: A Potential Drug Target For Inhibiting Virus Replication, Meghan Suzanne Warden

Chemistry & Biochemistry Theses & Dissertations

Picornaviruses are small, positive-stranded RNA viruses, divided into twelve different genera. Members of the Picornaviridae family cause a wide range of human and animal diseases including the common cold, poliomyelitis, foot and mouth disease, and dilated cardiomyopathy. The picornavirus genome is replicated via a highly conserved mechanism involving a presumed cloverleaf structure located at the 5’ noncoding region of the virus genome. The 5’ cloverleaf consists of three stem loops (B, C, and D) and one stem (A), which interact with a variety of virus and host cell proteins during replication. In this dissertation, human rhinovirus serotype 14 (HRV-14) SLB …

The Relationship Between Landing Error Scoring System-Real Time And Dorsiflexion Range Of Motion In Recreational Athletes, Hannah M. Twiddy

Human Movement Studies & Special Education Theses & Dissertations

Participation in physical activity is important for overall health; however, lower extremity injuries are a major risk associated with physical activity. Injuries can lead to time away from physical activity and be associated with negative health consequences. The most common injuries are traumatic injuries to the knee and ankle; which may be related to poor landing mechanics and decreased range of motion. Previous research utilizing motion analysis systems have determined people with greater dorsiflexion range of motion (DROM) demonstrated smaller ground reaction forces and greater knee and hip flexion displacement while landing; indicating a softer landing strategy. The ability to …

The Effects Of Fitness Level And Sex On Epoc Following High Intensity Interval And Moderate Intensity Aerobic Exercise, Rachel Lauren Simmons

Human Movement Studies & Special Education Theses & Dissertations

In the past few years, much attention has been directed toward shorter-duration vigorous intensity aerobic exercise as opposed to longer-duration moderate intensity exercise. There is conflicting evidence as to whether vigorous exercise can result in a greater excess post-exercise oxygen consumption (EPOC) and thus more calories burned when compared to moderate continuous exercise performed for a longer duration. In addition, the literature contains a dearth of information isolating and investigating male and female response to these exercises, as well as fit and unfit subjects. The purpose of this study was to quantify EPOC following moderate intensity aerobic exercise (MOD) and …

Intensity Of Exercise And Endothelial Function In Healthy Adults, Jacquelyn R. Moxey

Human Movement Studies & Special Education Theses & Dissertations

PURPOSE: To examine the effects of acute bouts of isocaloric exercise at different intensities on endothelial function. The flow-mediated dilation (FMD) responses after the different acute exercise bouts were compared to a control (no exercise) condition. METHODS: Nine healthy subjects completed the study (6 males, 3 females, X ± SD = 24 ± 5 yr, 1.75 ± 0.11 m, 79.2 ± 12.4 kg, 47.9 ± 6.9 mL•kg^-1•min^-1). Vascular responses were compared under three different conditions- HIT: a bout of high-intensity interval treadmill exercise consisting of ten 1-minute intervals at ~100% VO_2max; MOD: moderate-intensity exercise …

The Influence Of Interlimb Differences On Anterior Cruciate Ligament Injury Risk Factors In Female Collegiate Soccer Athletes, Eric Kevin Greska

Human Movement Studies & Special Education Theses & Dissertations

Female collegiate soccer athletes suffer anterior cruciate ligament (ACL) injuries at a rate of 0.31 per 1000 athlete-exposures, with 67% of injuries expected to be from a non-contact mechanism. As well, previous studies have demonstrated dissimilarity in non-contact ACL injuries relative to dominant and non-dominant legs; with the non-dominant leg being the involved side in 48-67% of reported incidents. The aim of this study was to examine lower extremity neuromechanics relative to leg dominance during an unanticipated sidestep cutting task, with differing states of fatigue and training.

Twenty female collegiate soccer players performed three valid trials for both the dominant …

Plantar Pressure Distribution Differences In Physically Active Individuals With And Without Functional Ankle Instability During A Side Cut, J'Nai Pittman

Human Movement Studies & Special Education Theses & Dissertations

Context: Functional ankle instability (FAI) is a popular condition in the physically active population. There is a surplus of evidence to demonstrate how FAI decreases proprioception, balance, and overall athletic performance. However, to date there is no evidence that demonstrates how F AI correlates to alterations in plantar pressure distribution differences in a physically active population while completing athletic tasks. Objective: To assess differences in plantar pressure distributions while completing a side cut in individuals with and without FAI. Design: Observational case-control. Setting: Outdoor field turf and research laboratory. Participants: Fifty ankles from physically active individuals (FAI: age= 21.47±3.02 yrs; …

The Comparison Of Hamstring/Quadriceps Strength Ratio In The Dominant Versus The Non-Dominant Leg Of Elite Female Artistic Gymnasts, Marina Moure

Human Movement Studies & Special Education Theses & Dissertations

The majority of the injuries in women's artistic gymnastics occur in the lower limbs (Marshall et al, 2007). Hamstring muscle strains are prevalent in sports that involve sprinting (Ekstrand & Quillist, 1985; Orchard, 2001; Croisier et al., 2008) with a high reinjury ratio (Orchard, 1993; Orchard, 1997). Recent studies have linked an increase of muscle injury rate in the lower limbs to strength muscle imbalance between legs and the relation between the hamstring and quadriceps strength (Croisier et al., 2002; Yamamoto, 2008; Sugiura et al, 2008). In order to determine if there is an imbalance in women's artistic gymnastics, forty-three …

Effect Of Body Mass And Added Mass On Treadmill Performance, Rachel Elizabeth Walker

Human Movement Studies & Special Education Theses & Dissertations

Strenuous physical activity in extreme environments is an important part of the activities of military personnel. The average infantry combat load for an infantry on the loaded tasks. Subjects performed an outdoor 4.8-km run and four maximal treadmill tests wearing the loads listed above. Subjects' pulmonary function was tested with load prior to each treadmill session. Peak values of heart rate, VO₂, exercise ventilation, and respiratory exchange ratio were measured at the end of each maximal treadmill test. Significant decreases were found in pulmonary function measures (FEV₁, FVC and MVV) with increasing load. Most peak responses …

The Correlation Between Visual Observations And Inclinometric Measurements For Special Tests Related To Patellofemoral Pain Syndrome, Erin Quada

Human Movement Studies & Special Education Theses & Dissertations

Patellofemoral pain syndrome (PFPS) is generally described as an insidious onset with pain increasing during running, jumping, ascending and descending stairs as well as sitting with the knees flexed for an extended period of time. Clinicians often use special tests in injury evaluations and range of motion assessments, usually making a visual observation of that status of the patient. The purpose of this study was to examine how interval measurements utilized in flexibility and range of motion assessments correlate with visual observations of special tests (active knee extension test, Thomas test, Ober's test, rectus femoris flexibility, and Craig's test). The …

The Effects Of Cocaine And Ecstasy On Cardiac Myocytes And The Intact Myocardium, David A. Tiangco

Theses and Dissertations in Biomedical Sciences

Cocaine and ecstasy are widely used illicit drugs. Both drugs have undergone intense scrutiny as information regarding their side-effects has become available. One important yet incomplete area of investigation pertains to their effects on the heart. The purpose of the current studies was to test the hypothesis that exposure to cocaine or ecstasy will adversely affect cellular homeostasis and normal heart function. Cultured cardiac myocytes (H9c2) and New Zealand White rabbits (Oryctolagus cuniculus) were used to measure the responses to various concentrations of cocaine or ecstasy at both the cellular and intact organ system levels. We observed that cocaine and …

Mechanisms Of Regulation Of Proximal Tubule Sodium Transporters In Obesity-Induced Hypertension, Marta A. Ambrozewicz

Theses and Dissertations in Biomedical Sciences

Hypertension is one of the common complications of obesity. Using a rat model of diet induced obesity and hypertension we investigated some of the mechanisms that are involved in regulation of blood pressure in obesity. The first aim of this study was to determine the role of proximal tubule transporters on the renal sodium handling in obese hypertensive (OP) and lean normotensive (OR) rats. An acute increase in renal perfusion pressure resulted in a blunted natriuretic response in OP vs. OR rats and indicated that increased sodium reabsorption in the proximal tubule is casual, at least in part, for hypertension …

The Effect Of Intensity Of Aerobic Training On Insulin Sensitivity, Carmine Richard Grieco Iii

Human Movement Studies & Special Education Theses & Dissertations

Epidemiological studies have demonstrated that the prevalence of type 2 diabetes is increasing. It is estimated that I 0. 7% of adults over the age of 20 years and 23.1 % of adults over the age of 60 years have diabetes (NIH, 2007). Individuals with type 2 diabetes are 2-4 times more likely to die from heart disease than those without diabetes and twice as likely to die of all-cause mortality (CDC, 2005). Additionally Mokdad et al. (2000) report that the prevalence of diabetes increased 33% between 1990 and 1998. Furthermore it has been estimated that nearly 26% of the …

The Effect Of Intensity Of Aerobic Vo2max Resting Heart Rate And Blood Pressure, Shannan Elizabeth Gormley

Human Movement Studies & Special Education Theses & Dissertations

The AGSM recommends 20 to 60 minutes of continuous or intermittent activity 3 to 5 times per week to maintain cardio respiratory fitness (Pollock et al., 1998). The 1996 Surgeon General's Report on Physical Activity and Health indicates that Americans are not meeting these physical activity recommendations (DHHS). Several clear consequences of physical inactivity are the appearance of cardiovascular disease risk factors, such as hypertension, hyperlipidemia and obesity. Two recent review articles suggested that higher intensity exercise will elicit a greater reduction in cardiovascular disease risk factors (Swain and Franklin, 2002; Swain and Franklin, 2006). In order to determine whether …

The Effect Of Instruction Of Jump-Landing Motion Patterns And Impact Forces, Mary Elizabeth Joos

Human Movement Studies & Special Education Theses & Dissertations

The use of visual instruction could be a valuable tool in prevention strategies for anterior cruciate ligament injuries, especially in large group settings, through the alterations of jump-landing motion patterns and impact forces. The purpose of this study was to determine the effectiveness of two visual modeling cues in altering jump-landing motion patterns, as measured by the Landing Error Scoring System (LESS), and impact forces, vertical ground reaction force (PVGRF) and peak posterior ground reaction force (PPGRF). Seventy-three physically active individuals (age= 20.89 ± 1.72 years; height = 172 ± 9.87 cm; mass= 68.43 ± 15.97 kg) were baseline tested …

The Study Of Nitric Oxide Synthase Expression, Function, And Regulation In The Renal Vasculature During Postnatal Renal Development, Brian Blake Ratliff

Theses and Dissertations in Biomedical Sciences

The newborn kidney is vulnerable to vasomotor acute renal failure (ARF) from adverse perinatal events or complications of prematurity. Nitric oxide (NO) vasodilation is vitally protective in this type of ARF, but its relationship with other vasoactive factors, such as angiotensin II (AII) has not been examined. In the immature kidney, nitric oxide synthase (NOS) isoforms, specifically eNOS and nNOS, are developmentally regulated, but their specific role and regulation are unknown.

The enhanced vasodilatory role of NO in the immature kidney was hypothesized to be attributed to regulatory, expressional, and functional differences in eNOS and nNOS isoforms from the adult. …

Hybridization Between The Watersnakes Nerodia Sipedon And Nerodia Fasciata, In The Carolinas: A Morphological And Molecular Approach, Konrad Mebert

Biological Sciences Theses & Dissertations

A few traditionally applied diagnostic characters of color pattern were compared with an additional set of morphological and genetic characters to evaluate differences between Nerodia sipedon and N. fasciata and to study the dynamics across their hybrid zone in the Carolinas. Many of the morphological characters exhibited significant interspecific differences, although only the number of dorsally complete crossbands (CBa) was diagnostic by itself. A discriminant function analysis of morphological characters was successful in separating both taxa. Species-specific nuclear markers, identified by the AFLP (Amplified Fragment Length Polymorphism) technique were nearly fixed and served as diagnostic markers. They revealed extensive introgression …

The Effects Of A 10-Week Exercise Program On Physiological Variables And Quality Of Life In Type 2 Diabetes, David Robb Holton

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to determine the interaction between psychological and physiological parameters before and after a 10-week, aerobic training study of sedentary diabetic individuals and sedentary controls. Tests measuring physiological parameters (interstitial NO, blood flow, lactate threshold, VO₂ peak and glycosylated hemoglobin) and a quality of life survey were completed before and after training. Nine previously sedentary diabetic (DE, diabetic exerciser) and 10 control sedentary subjects (CE, control exerciser) engaged in 10 weeks of supervised aerobic exercise. A non-training diabetic group (DS, diabetic sedentary, n=12) and a non-training control group (CS, control sedentary, n=I0) were also …

Estrogen Regulation Of The Pregnant Baboon Placental 11Β-Hydroxysteroid Dehydrogenase (11Β-Hsd)-Catalyzed Metabolism Of Cortisol And Cortisone And Its Effect On The Development Of The Fetal Hypothalamic-Pituitary-Adrenal Axis, William Adair Davies

Theses and Dissertations in Biomedical Sciences

Pepe and Albrecht previously demonstrated that the estrogen-regulated change in transuteroplacental metabolism of cortisol (F) and cortisone (E) from preferential reduction (E to F) at midgestation to oxidation (F to E) near term results in a decline of bioactive cortisol crossing the placenta and reaching the fetus culminating in activation of the hypothalamic-pituitary adrenal axis of the baboon and the ontogenesis of rate-limiting steroidogenic enzymes culminating in de novo F secretion. Protein kinase A (PK-A) activity in the baboon fetal adrenal gland cytosolic fraction was increased 2-fold both at term [day 165 of gestation (term = 184 days)] and following …

Role Of Lipolysis And Lipogenesis In The Development Of Diet-Induced Obesity, Michael John Davies

Theses and Dissertations in Biomedical Sciences

Obesity is an increasingly common public health problem with approximately one-half of the American adult population overweight and one-quarter considered obese. This alarming trend has led researchers to determine potential causative factors of excess weight gain in humans. However, it is difficult to discern whether perturbations that result in obesity are the cause or simply the result of the obese state. Diet-induced obesity is one of the animal models that allow researchers to address temporal issues. Our laboratory utilizes a diet-induced obesity model in which Sprague-Dawley rats are placed on a purified moderately high fat diet and ultimately diverge into …

An Ultrastructural Survey Of The Nuchal Glands Of Rhabdophis Tigrinus (Serpentes: Colubridae), Kathleen A. Roberts

Biological Sciences Theses & Dissertations

Rhabdophis tigrinus, an Asian natricine snake, possesses a series of integumentary glands located in the nuchal skin. Previous studies indicated that the nuchal glands are of mesodermal origin, contain cardiac steroids analogous to bufotoxins found in the parotoid glands of toads, which are included in the snake's diet. The nuchal glands are defensive in function. Preliminary histological studies revealed differences in quality of the gland tissue compared to previous studies, and difference in fixation techniques were suspected. Seven specimens of R. tigrinus were fixed by perfusion using a conservative fixation process standard for electron microscopy. The nuchal gland series …

Abnormal Electrical Potentials In Lower Limb Muscles After Ankle Sprain Grades I, Ii And Iii, Talal A. Al-Shatti

Rehabilitation Sciences Theses & Dissertations

Fibrillation and positive sharp wave potentials have been found after ankle sprain in muscles around the injured joint. The purpose of this study was to better define and explain the reaction of the muscles around the ankle joint after grades I, II and m ankle sprains. Methods: Fifteen subjects (9 males and 6 females, mean age of 33.2 years) with ankle sprains voluntarily participated in this study. A stress x-ray was done to determine the grade of ankle sprain. Nerve conduction velocity and EMO studies were done three weeks after the injury. None of the patients in this study manifested …

The Effects Of Dehydration And Rehydration On The One-Repetition Maximum Bench Press Of Weight Trained Males, James E. Schoffstall

Human Movement Studies & Special Education Theses & Dissertations

The purpose of this study was to examine the effects of dehydration and rehydration on the one repetition maximum (1-RM) bench press of weight trained males. The ten subjects displayed the following characteristics: 25.3 ± 3.2 years old, 85.5 ± 16.4 kilograms body mass and a 117.9 ± 24.0 kilogram base-line 1-RM. Ten subjects were tested on two separate days, with one week between each test day. The subjects were randomly assigned to begin their testing in either the A protocol or the B protocol. During the A protocol testing day, the subjects completed two one repetition maximum bench press …

Patellofemoral Joint Compressive Forces During Backward And Forward Running At The Same Speed, Hesham N. Alrowayeh

Rehabilitation Sciences Theses & Dissertations

A previous study found that the patellofemoral joint compressive force (PFJRF) during backward running was less than during forward running at free speed. Therefore, the purpose of this study was to compare the patellofemoral joint compressive forces during backward and forward running at the same speed. Ten runners (4 females, 6 males) between the age of 20-25 (X=22, SD=2) ran in backward and forward directions at the slow speed of 2.3 mph (1.0 m.sec^-1). Using the inverse dynamic technique the knee extensor moment and PFJRF during the slow backward and forward running were calculated. Results showed that the …

Comparison Of The Emg Activity Of The Supraspinatus And Infraspinatus Muscles During Various Closed Chain Exercises, I-Chen Lin

Rehabilitation Sciences Theses & Dissertations

Advantages of closed chain exercises used in the lower extremity have been well documented. However, the effects of closed chain exercises on the upper extremities have not been studied very much. Thus, the purpose of this research is to analyze the EMG activity of the supraspinatus and infraspinatus muscles and compare the relative amounts of activities by performing different isotonic closed chain exercises and an open chain exercise in normal subjects. The supraspinatus and infraspinatus muscles in 1 o healthy subjects were studied with fine wire, intramuscular, electromyographic electrodes while performing 5 closed chain exercises and a D2. open chain …