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Full-Text Articles in Physiology
The Role Of The Salivary Glands In Uptake Of Fluoride In Teeth And Bone, Robin E. Vance
The Role Of The Salivary Glands In Uptake Of Fluoride In Teeth And Bone, Robin E. Vance
Loma Linda University Electronic Theses, Dissertations & Projects
The cariostatic capability of fluoride is generally recognized, in addition, it may also have a beneficial effect on bone. Fluoride is thought to exercise its cariostasis through a local effect on teeth, however, the possibility exists that fluoride exerts its action through a systemic mechanism. Fluoride uptake by rat teeth and its effectiveness as a cariostatic substance was studied in parotidectomized, submaxillariectomized, and totally sialoadenectomized animals (both parotid and submaxillary glands removed). The uptake of fluoride in bone was also quantitated for comparison purposes.
Rats were injected daily with 15 micromoles of fluoride dissolved in 0.1 ml saline. The rats …
Age-Related Changes Of Neurites In Meissner Corpuscles Of Diabetic, Vicky R. Ras
Age-Related Changes Of Neurites In Meissner Corpuscles Of Diabetic, Vicky R. Ras
Loma Linda University Electronic Theses, Dissertations & Projects
This thesis is based on a qualitative and quantitative study of the neural component of Meissner corpuscles of diabetic and non-diabetic mice. Age-related changes were also documented in these mechanoreceptors. Corpuscles from forty-six diabetic mice and forty-six non-diabetic mice ranging from 2.5 to 17 months old were studied. Forepaw index digital pads were formalin-fixed and frozen-sectioned parallel to each digit and perpendicular to the skin. Serial sections were then silver-impregnated to allow light microscopic examination of the neurites in the corpuscles.
Neurites became more coarse, tortuous, branched, varicose, and thus more complex until middle age. Corpuscle size appeared greatest at …