Nutrition Commons^™

The Effect Of Vitamin D3 Supplementation On Advanced Glycation End Products, (Ages) And Soluble Receptor, (Srage) In African Americans And Hispanics With Type 2 Diabetes And Vitamin D Insufficiency/Deficiency, Justina Serwaah Owusu

FIU Electronic Theses and Dissertations

There is a high burden of diabetes and its related complications globally. Advanced Glycation End Products (AGEs) and their receptors have been implicated in complications and mortality related to type 2 diabetes (T2D). Vitamin D deficiency, prevalent in persons with T2D, increases oxidative stress and inflammation that promotes the formation of AGEs.

This study assessed the relationship between sRAGE and AGEs and risk of cardiovascular diseases (CVD) and the effect of vitamin D3 supplementation on levels of AGEs and soluble receptor (sRAGE) in adults with hypovitaminosis D. African Americans and Hispanics (n=64) were recruited in Miami and were supplemented with …

The Effect Of Vitamin D3 Supplementation On Kidney Function And Cardiovascular Disease Markers Among Hispanics And African Americans With Type 2 Diabetes, Gustavo G. Zarini

FIU Electronic Theses and Dissertations

Serum vitamin D deficiency/insufficiency, Chronic Kidney Disease (CKD) and elevated blood pressure are important health concerns especially among minorities with type 2 diabetes. The effect of vitamin D₃ supplementation (cholecalciferol) at 6,000 IU/day (d) vs. 4,000 IU/d on kidney function and cardiovascular disease markers among Hispanics and African Americans with type 2 diabetes and hypovitaminosis D (/ml) was evaluated. Subjects (n=63) were recruited from two clinics in Miami-Dade County, FL. Fasting venous blood and fresh, single-voided first morning urine samples were collected from each participant by a certified phlebotomist and analyzed by Solstas Lab Partners, Davie, FL. Linear mixed …

The Effect Of Vitamin D Supplementation On Cardiovascular Risk Factors Among Minorities With Type 2 Diabetes, Joel Exebio

FIU Electronic Theses and Dissertations

The aim of the present study was to determine the effect of vitamin D supplementation (4000 IU or 6000 IU of cholecalciferol daily for 6 months) on fasting plasma glucose, fasting insulin, glycated hemoglobin, and lipid profile in a sample of African-Americans and Hispanics with T2D and vitamin D insufficiency. Seventy five participants were recruited by community outreach. Plasma glucose concentration was measured by hexokinase enzymatic method. Glycated hemoglobin was measured by the DCA2000+ system. Insulin in fasting blood was determined by radioimmunoassay. Plasma total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein cholesterol were assayed by enzymatic methods. Serum vitamin …