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Full-Text Articles in Neuroscience and Neurobiology

Gpr171 Modulates Mood, Consummatory Behaviors, And Morphine Antinociception In A Sexually Dimorphic Pattern In Mice, Megan C. Raddatz Aug 2024

Gpr171 Modulates Mood, Consummatory Behaviors, And Morphine Antinociception In A Sexually Dimorphic Pattern In Mice, Megan C. Raddatz

All Graduate Theses and Dissertations, Fall 2023 to Present

Receptors in the brain influence everything from complex behaviors related to mood, all the way to simple physiological functions like the way a person moves. Receptors are activated or inactivated by chemicals or hormones that the body produces or that are created to mimic the body’s natural chemicals. Of the hundreds of receptors in the brain, GPR171 is particularly interesting because new drugs have been created to activate or block the receptor, and are being proposed for the treatment of different disorders, particularly disorders related to pain. GPR171 has been shown to affect pain behaviors, eating, and mood-related behaviors, but …


Ethnicity, Perceptions Of Stress, And Depressive Symptoms Among Female Undergraduate Students, Claudia Priscilla Cobos Jan 2019

Ethnicity, Perceptions Of Stress, And Depressive Symptoms Among Female Undergraduate Students, Claudia Priscilla Cobos

Walden Dissertations and Doctoral Studies

Individuals have suffered from depression for decades. Although depression is under diagnosed, it is one of the most common disorders seen by psychiatrists. The purpose of this research study was to understand whether students' perceived stress level was a significant predictor of students' depressive symptoms. The study explored social cognitive theory to assist in understanding the relationship between depressive symptoms and perceived stress in female minority students. Although depressive symptoms and perceived stress in students have been explored exhaustively, these variables had not been explored specifically among minority students and then compared to nonminority students. Using the Center for Epidemiologic …


The Use Of Doublecortin To Quantify The Effects Of Pharmacological Treatment On Neurogenesis And Functional Recovery After Stroke, Amber Lee Hensley Jan 2016

The Use Of Doublecortin To Quantify The Effects Of Pharmacological Treatment On Neurogenesis And Functional Recovery After Stroke, Amber Lee Hensley

Browse all Theses and Dissertations

Ischemic strokes account for 87% of all strokes and can have debilitating effects on language, sensory, and motor skills. Currently, tPA is the only medication approved by the FDA for the treatment of ischemic stroke, but the window of time to administer the drug is very small. In this thesis, we investigate the use of a simvastatin and fluoxetine drug combination (FS) as a possible treatment for ischemic stroke victims. To analyze the effects of FS on neurogenesis and functional recovery, we utilize the Montoya Staircase and quantify the amount of neurogenesis using doublecortin. Although the results of this study …


Characterization Of The Behavioral, Biochemical And Molecular Indices Of Stress Produced By Nicotine Exposure And Withdrawal In Male And Female Rats, Oscar Valentin Torres Jan 2012

Characterization Of The Behavioral, Biochemical And Molecular Indices Of Stress Produced By Nicotine Exposure And Withdrawal In Male And Female Rats, Oscar Valentin Torres

Open Access Theses & Dissertations

Introduction: Tobacco use is a major economic and health problem. Particularly concerning is that women consume more tobacco products, have a more difficult time quitting, and are less likely to benefit from cessation therapies than men. As a result, women are at higher risk of developing tobacco-related diseases. Women are generally more susceptible to stress and are more likely to cope with stress by smoking as compared to men. During abstinence, women also experience intense anxiety as compared to men and report that the anxiety-reducing effects of smoking are the main reason for continued use and relapse. Thus, stress produced …