Open Access. Powered by Scholars. Published by Universities.®

Pathogenic Microbiology Commons

Open Access. Powered by Scholars. Published by Universities.®

2015

Algae

Articles 1 - 1 of 1

Full-Text Articles in Pathogenic Microbiology

A Lipidomics Approach To The Viral-Host Dynamics Of The Unicellular, Eukaryotic Alga Chlorella Variabilis And Its Viral Pathogen, Pbcv-1, Suzanne Rose Dec 2015

A Lipidomics Approach To The Viral-Host Dynamics Of The Unicellular, Eukaryotic Alga Chlorella Variabilis And Its Viral Pathogen, Pbcv-1, Suzanne Rose

Dissertations and Theses in Biological Sciences

This thesis focuses on the sterol and sphingolipid composition in the unicellular, green alga Chlorella variabilis and the lipidomic changes that occur during viral infection. Using lipid analysis by mass spectrometry, we have identified the major sterol, ergosterol and sphingolipid, glucosyl inositol phosphoceramide (GIPC) as constituents of C. variabilis cell membranes. Sterols and sphingolipids have essential biological functions such as hormone-based signaling, plant defense, and apoptosis as well as critical roles in structural components of the cell and organelle membranes. In chapters two and three, we focus on the characterization of sterol composition among both freshwater and marine alga and ...