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Articles 1 - 4 of 4
Full-Text Articles in Pathogenic Microbiology
Weaving An Interdisciplinary Microbiome Career Using Threads From Different Ecosystems, Sarah Hosler
Weaving An Interdisciplinary Microbiome Career Using Threads From Different Ecosystems, Sarah Hosler
Electronic Theses and Dissertations
Animals have trillions of microorganisms living in or on many body sites, these communities of microorganisms are called microbiomes. Microbiomes are typically host-specific, and a lot of information about the host can be determined from investigating them. Microbiome research has many real-world applications, and this thesis utilizes the One Health perspective, which acknowledges the connection of humans, animals, and environments, and emphasizes the need for collaborative, interdisciplinary research. The first interdisciplinary project is an investigation into the bacteria in wild and cultured Atlantic deep-sea scallop, Placopecten magellanicus larvae. Adults in hatcheries can be induced to spawn, but the last two …
Intravital Imaging In A Zebrafish Model Elucidates Interactions Between Mucosal Immunity And Pathogenic Fungi, Linda S. Archambault
Intravital Imaging In A Zebrafish Model Elucidates Interactions Between Mucosal Immunity And Pathogenic Fungi, Linda S. Archambault
Electronic Theses and Dissertations
Candida yeasts are common commensals that can cause mucosal disease and life-threatening systemic infections. While many of the components required for defense against Candida albicans infection are well established, questions remain about how various host cells at mucosal sites assess threats and coordinate defenses to prevent normally commensal organisms from becoming pathogenic. Using two Candida species, C. albicans and C. parapsilosis, which differ in their abilities to damage epithelial tissues, we used traditional methods (pathogen CFU, host survival, and host cytokine expression) combined with high-resolution intravital imaging of transparent zebrafish larvae to illuminate host-pathogen interactions at the cellular level …
Dynamic Host-Pathogen Interactions Result In Fungal Epitope Unmasking, Alex Hopke
Dynamic Host-Pathogen Interactions Result In Fungal Epitope Unmasking, Alex Hopke
Electronic Theses and Dissertations
Molecular camouflage is used by a diverse set of pathogens to disguise their identity and avoid recognition by protective host receptors. The opportunistic fungal pathogen Candida albicans is a good example, as it masks the inflammatory component β-glucan in its cell wall to evade detection by the immune receptor Dectin-1. Interestingly, it has been seen that β-glucan becomes unmasked during infection in vivo, though the underlying mechanisms remained unclear. Exposure levels of this epitope may be important, as Dectin-1 mediates protection from some strains of C. albicans and alterations in the organization and composition of the Candida cell wall …
First Evidence For A Vibrio Strain Pathogenic To Mytilus Edulis Altering Hemocyte Immune Capacities, Yosra Ben Cheikh
First Evidence For A Vibrio Strain Pathogenic To Mytilus Edulis Altering Hemocyte Immune Capacities, Yosra Ben Cheikh
2nd International Conference of Fish & Shellfish Immunology
No abstract provided.