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Articles 1 - 4 of 4
Full-Text Articles in Pathogenic Microbiology
Frankenbacteriosis Targeting Interactions Between Pathogen And Symbiont To Control Infection In The Tick Vector, Lorena Mazuecos, Pilar Alberdi, Angélica Hernández-Jarguín, Marinela Contreras, Margarita Villar, Alejandro Cabezas-Cruz, Ladislav Simo, Almudena González-García, Sandra Díaz-Sánchez, Girish Neelakanta, Sarah I. Bonnet, Erol Fikrig, José De La Fuente
Frankenbacteriosis Targeting Interactions Between Pathogen And Symbiont To Control Infection In The Tick Vector, Lorena Mazuecos, Pilar Alberdi, Angélica Hernández-Jarguín, Marinela Contreras, Margarita Villar, Alejandro Cabezas-Cruz, Ladislav Simo, Almudena González-García, Sandra Díaz-Sánchez, Girish Neelakanta, Sarah I. Bonnet, Erol Fikrig, José De La Fuente
Biological Sciences Faculty Publications
(Summary) Tick microbiota can be targeted for the control of tick-borne diseases such as human granulocytic anaplasmosis (HGA) caused by model pathogen, Anaplasma phagocytophilum. Frankenbacteriosis is inspired by Frankenstein and defined here as paratransgenesis of tick symbiotic/commensal bacteria to mimic and compete with tick-borne pathogens. Interactions between A. phagocytophilum and symbiotic Sphingomonas identified by metaproteomics analysis in Ixodes scapularis midgut showed competition between both bacteria. Consequently, Sphingomonas was selected for frankenbacteriosis for the control of A. phagocytophilum infection and transmission. The results showed that Franken Sphingomonas producing A. phagocytophilum major surface protein 4 (MSP4) mimic pathogen and reduce infection …
Super-Killers: Environmental Isolates That Antagonize Pathogenic Vibrio, Abigail Joy
Super-Killers: Environmental Isolates That Antagonize Pathogenic Vibrio, Abigail Joy
Honors Projects
Vibrio are members of a bacterial group that thrive in diverse aquatic environments including on the surface of aquatic animals, free-living in the water column, and in association with suspended particles. The total Vibrio counts in the coastal ocean ranges from 103-105 per milliliter of water depending on seasons and water temperature. Although many different species of Vibrio persist in the water column, pathogenic strains, such as Vibrio cholerae and Vibrio parahaemolyticus are absent or rare in marine environments. We hypothesize that the low abundance of these pathogenic species may be due to interspecific competition among environmental …
Characterization Of The Microbial Associates Of Nematodes Pathogenic To Myrmica Rubra, Jonathan E. Dumont
Characterization Of The Microbial Associates Of Nematodes Pathogenic To Myrmica Rubra, Jonathan E. Dumont
Honors College
Pristionchus entomophagus is a necromenic nematode commonly associated with dung beetles (Geotrupes spp.) in Europe. Recently, it has been found in Maine emerging from cadavers of M. rubra, an ant native to Europe that is currently established and pestiferous in Maine (Groden and Stack 2011). Laboratory assays inoculating M. rubra with these nematodes caused significant mortality. This study aimed to characterize the bacterial associates of P. entomophagus in order to further understand its pathogenic relationship with M. rubra. Bacterial samples were collected from the cuticle and gut of the nematodes, and the hemolymph of infected hosts. Single spore isolates were …
On The Evolution Of Sexually Transmitted Diseases In Birds, Michael Lombardo
On The Evolution Of Sexually Transmitted Diseases In Birds, Michael Lombardo
Michael P Lombardo
"The definitive version is available at www.blackwell-synergy.com".
Sexually transmitted diseases (STDs) in animals are caused by pathogens that are transmitted during copulation. Birds have played an important role in the development of STD-centered theories of mating behavior. However, it is not known whether STDs exist in wild bird populations. While the avian cloaca with its dual functions of gamete transfer and excretion seemingly predisposes birds for the evolution of STDs, the life history patterns of most birds (i.e., seasonal breeders with relatively brief annual periods of sexual activity) suggest otherwise. The importance of STDs as selective forces that shape host …