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Molecular Biology Commons

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1990

Cellular

Genetics

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Full-Text Articles in Molecular Biology

Genetic And Molecular Analyses Of Suppressor Of Forked In Drosophila Melanogaster , Cynthia Lynn Fitch-Steenson Jan 1990

Genetic And Molecular Analyses Of Suppressor Of Forked In Drosophila Melanogaster , Cynthia Lynn Fitch-Steenson

Retrospective Theses and Dissertations

Mutations at the suppressor of forked, su(f), locus are trans-acting, allele specific suppressors and enhancers of mutations at certain other loci. Su(f) is a trans-acting regulator whose normal product is necessary for proper transcription of these genes. The su(f) product regulates the transcription of transposable elements located within these genes. Our investigation includes a genetic analysis in which a number of new su(f) alleles were isolated, a development analysis in which the effects of new alleles and allelic combinations were characterized, and a molecular analysis in which a cloned genomic DNA fragment containing su(f) was ...