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Molecular Biology Commons

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1990

Iowa State University

Zoology

Articles 1 - 1 of 1

Full-Text Articles in Molecular Biology

Molecular Characterization Of The Yeast Gene Hsp60 , Donald Stevenson Reading Jan 1990

Molecular Characterization Of The Yeast Gene Hsp60 , Donald Stevenson Reading

Retrospective Theses and Dissertations

In all organisms studied, heat shock or other stressful stimuli lead to profound changes in gene expression. During heat shock, a small group of evolutionarily conserved proteins, termed heat shock proteins (hsps), are synthesized in abunDance; Several hsps are known to have vital cellular function even at normal temperature. These hsps have the capacity to bind polypeptide chains and have a probable role in the folding, translocation, and assembly pathways of many proteins. One such protein, hsp60, is located within mitochondria, is highly conserved in evolution, and based on immunological and physical characterization, is a member of a family of ...