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Molecular Biology Commons

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Theses/Dissertations

And developmental biology

Genetics

1995

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Full-Text Articles in Molecular Biology

Sequence Variation Characteristics Of D-Loop, Rrna, Trna, And Polypeptide Coding Region Of Bovine Mitochondrial Dna , Jianming Wu Jan 1995

Sequence Variation Characteristics Of D-Loop, Rrna, Trna, And Polypeptide Coding Region Of Bovine Mitochondrial Dna , Jianming Wu

Retrospective Theses and Dissertations

By cloning and sequencing the mtDNA of cows from different maternal lineages, it was found that multiple heteroplasmic mtDNA states within the D-loop and rRNA genes of mtDNA existed extensively in Holstein cattle. Meanwhile, the nature and transmission of mtDNA were investigated. The mtDNA population in a specific animal was found to be a mixture of different genotypes. Because heteroplasmy was observed frequently and seemingly is persistent, selected amplification of specific mtDNA molecules may not be a part of mtDNA inheritance. At same time, four hypervariable sites were located at nt 169, 216, and 1594 between nt 352 to 364 ...