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Clpxp Modulates Cell Growth And Morphology In Cell Shape Mutants Of E.Coli, Ryann Murphy
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ClpXP modulates cell growth and morphology in cell shape mutants of E. coli
Ryann Murphy1 and Jodi L. Camberg1
1University of Rhode Island, Department of Cell and Molecular Biology, Kingston, RI, 02881
Penicillin Binding Proteins (PBPs) are a family of prokaryotic membrane proteins named for their propensity to bind the antibiotic penicillin and are involved in remodeling and deposition of peptidoglycan. In wild type Escherichia coli cells, the uniform rod shape is conserved across generations. E.coli cells containing multiple deletions of Low Molecular Weight (LMW) PBPs exhibit irregular shapes. LMW PBP5 (dacA) is a potential substrate ...