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Improving Dna Quality Using Ffpe Tissues For Array Comparative Genomic Hybridization To Find Single Nucleotide Polymorphisms (Snps) In Melanoma, Keerti Potluri

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Important classes of benign and malignant neoplasms are composed of melanocytic cells which produce a pigment called melanin. Benign nevi, which are non-malignant melanocytic lesions, can sometimes give rise to malignant melanoma. Melanoma can be a lethal melanocytic neoplasm, a deadly and aggressive form of skin cancer. Finding prognostic or diagnostic markers can be very useful to reduce the deaths caused by melanoma. Array Comparative Genomic Hybridization (aCGH), a cytogenetic technique, analyzes the whole genome or chromosome for detecting genetic aberrations/variations such as single nucleotide polymorphisms (SNPs) in a cancer. formalin fixed paraffin embedded FFPE tissues are usually taken from …