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Full-Text Articles in Molecular Biology
Annual Faculty Research Symposium 2022, Oakwood University
Annual Faculty Research Symposium 2022, Oakwood University
Proceedings
No abstract provided.
Enzyme Characterization Of Human Inorganic Pyrophosphatase, Christopher Sebastian, Manavalan Gajapathy
Enzyme Characterization Of Human Inorganic Pyrophosphatase, Christopher Sebastian, Manavalan Gajapathy
Research Horizons Day Posters
No abstract provided.
Modeling Atp-Binding Cassette G2 (Abcg2) Substrate Specificity, Raghav D. Acharya, Aurijit Sarkar, Glen E. Kellogg
Modeling Atp-Binding Cassette G2 (Abcg2) Substrate Specificity, Raghav D. Acharya, Aurijit Sarkar, Glen E. Kellogg
Undergraduate Research Posters
How well can we predict efflux by ATP-binding cassette G2?
It is estimated that there will be about 1.6 million new cases of cancer and half a million cancer deaths in the US during 2015.ATP-binding cassette (ABC) efflux transporters such as ABCG2 are overexpressed in chemotherapy-resistant cancer cells. Anticancer drugs are prone to efflux by these transporters. Being able to identify drugs that are effluxed is of great interest in drug discovery.The current arsenal of methods used to detect efflux are not easily adaptable to high throughput formats and are limited in scope, making experimental analysis an expensive prospect. Hence, …