Life Sciences Commons^™

A Scientometric Appreciation Of Robert J. Baker's Contributions To Science And Mammalogy, David J. Schmidly, Robert D. Bradley, Emma K. Roberts, Lisa C. Bradley, Hugh H. Genoways

Mammalogy Papers: University of Nebraska State Museum

This article describes Robert James Baker’s academic pedigree and genealogy, his scientific productivity (number of publications), his citations, his students, his contributions to his university and scientific societies, his personality in relation to his scientific achievements, his legacy, and a personal note of appreciation by individuals who worked with him and knew him well. His accomplishments are compared with other dominant personalities in the field of mammalogy, both historical and contemporary. The paper builds on the 2018 obituary authored by Hugh Genoways and others that was published in the Journal of Mammalogy, but includes a much more quantitative and ...

Tackling New Federal Agency Public Access Mandates At The University Of Arizona, Ahlam A. Saleh, Christine Kollen, Dan Lee, Scott Pryor, Lori Schultz

University of Massachusetts and New England Area Librarian e-Science Symposium

Objective: In 2014, federal agencies began releasing their implementation plans in response to the 2013 White House’s Office of Science and Technology Policy (OSTP) Increasing Access to the Results of Federally Funded Research policy memorandum. The University has in place an established Data Management support service, which has addressed new data requirements. However, in early 2016 the University of Arizona Libraries (UAL) and Office of Research, Discovery & Innovation (RDI) convened to discuss how the university can help researchers address these new growing federal agency mandates on manuscripts and data.

Methods: By the summer of 2016, a collaboration of UA ...

Atlanta University Center Faculty Publications: A Selective Bibliography, Robert W. Woodruff Library

Atlanta University Center Faculty Scholarship Bibliographies

On February 28, 2006, the Robert W. Woodruff Library and the Library Advisory Council hosted an exhibit and reception to celebrate the scholarly publications of Atlanta University Center faculty. As a complement to that event, the Robert W. Woodruff Library developed the publication, Atlanta University Center Faculty Publications: A Brief Bibliography, which highlights selected scholarly and research contributions of the Atlanta University Center faculty.

The bibliography illustrates the richness of faculty contributions within each institution and across the Atlanta University Center community. The celebration has become an annual event and this compilation represents the next phase of a living document ...

Data Publication With The Structural Biology Data Grid Supports Live Analysis, Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Oleg V. Tsodikov

Pharmaceutical Sciences Faculty Publications

Access to experimental X-ray diffraction image data is fundamental for validation and reproduction of macromolecular models and indispensable for development of structural biology processing methods. Here, we established a diffraction data publication and dissemination system, Structural Biology Data Grid (SBDG; data.sbgrid.org), to preserve primary experimental data sets that support scientific publications. Data sets are accessible to researchers through a community driven data grid, which facilitates global data access. Our analysis of a pilot collection of crystallographic data sets demonstrates that the information archived by SBDG is sufficient to reprocess data to statistics that meet or exceed the quality ...

Atlanta University Center Faculty Publications: A Selective Bibliography, Robert W. Woodruff Library

Atlanta University Center Faculty Scholarship Bibliographies

On February 28, 2006, the Robert W. Woodruff Library and the Library Advisory Council hosted an exhibit and reception to celebrate the scholarly publications of Atlanta University Center faculty. As a complement to that event, the Robert W. Woodruff Library developed the publication, Atlanta University Center Faculty Publications: A Brief Bibliography, which highlights selected scholarly and research contributions of the Atlanta University Center faculty.

The bibliography illustrates the richness of faculty contributions within each institution and across the Atlanta University Center community. The celebration has become an annual event and this compilation represents the next phase of a living document ...

Characterization Of Antimicrobial Susceptibility Profile Of Biofield Treated Multidrug-Resistant Klebsiella Oxytoca, Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Harish Shettigar, Mayank Gangwar, Snehasis Jana

Mahendra Kumar Trivedi

Iarc Monographs: 40 Years Of Evaluating Carcinogenic Hazards To Humans, Neil E. Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersom, Josep M. Anto, Bruce K. Armstrong, Andrea A. Baccarelli, Frederick A. Beland, Amy Berrington, Pier Alberto Bertazzi, Linda S. Birnbaum, Ross C. Brownson, John R. Bucher, Kenneth P. Cantor, Elisabeth Cardis, John W. Cherrie, David C. Christiani, Pierluigi Cocco, David Coggon, Pietro Comba, Paul A. Demers, John M. Dement, Jeroen Douwes, Ellen A. Eisen, Lawrence S. Engel, Richard A. Fenske, Lora E. Fleming, Tony Fletcher, Elizabeth Fontham, Francesco Forastiere, Rainer Frentzel-Beyme, Lin Fritschi, Michel Gerin, Marcel Goldberg, Philippe Grandjean, Tom K. Grimsrud, Per Gustavsson, Andy Haines, Patricia Hartge, Johnni Hansen, Michael Hauptmann, Dick Heederik, Kari Hemminki, Denis Hemon, Irva Hertz-Picciotto, Jane A. Hoppin, James Huff, Bengt Jarvholm, Daehee Kang, Margaret R. Karagas

Open Dartmouth: Peer-reviewed articles by Dartmouth faculty

Background: Recently, the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also for the approach used to perform these evaluations. Some critics have claimed that failures of IARC Working Groups to recognize study weaknesses and biases of Working Group members have led to inappropriate classification of a number of agents as carcinogenic to humans.

Objectives: The authors of this Commentary are scientists from various disciplines relevant to the identification and hazard evaluation of human carcinogens. We examined criticisms of the IARC classification process ...

Bcl-2 Family Protein, Bad Is Down-Regulated In Breast Cancer And Inhibits Cell Invasion., Maria Cekanova, R Fernando, N Siriwardhana, M Sukthankar, Cde Parra, J Woraratphoka, C Malone, A Strom, Seung Baek, P Wade, A Saxton, Robert Donnell, R Pestell, S Dharmawardhane, J Wimalasena

Seung J Baek

We have previously demonstrated that the anti-apoptotic protein BAD is expressed in normal human breast tissue and shown that BAD inhibits expression of cyclin D1 to delay cell-cycle progression in breast cancer cells. Herein, expression of proteins in breast tissues was studied by immunohistochemistry and results were analyzed statistically to obtain semi-quantitative data. Biochemical and functional changes in BAD-overexpressing MCF7 breast cancer cells were evaluated using PCR, reporter assays, western blotting, ELISA and extracellular matrix invasion assays. Compared to normal tissues, Grade II breast cancers expressed low total/phosphorylated forms of BAD in both cytoplasmic and nuclear compartments. BAD overexpression ...

Bcl-2 Family Protein, Bad Is Down-Regulated In Breast Cancer And Inhibits Cell Invasion., Maria Cekanova, R Fernando, N Siriwardhana, M Sukthankar, Cde Parra, J Woraratphoka, C Malone, A Strom, Seung Baek, P Wade, A Saxton, Robert Donnell, R Pestell, S Dharmawardhane, J Wimalasena

Maria Cekanova MS, RNDr, PhD

We have previously demonstrated that the anti-apoptotic protein BAD is expressed in normal human breast tissue and shown that BAD inhibits expression of cyclin D1 to delay cell-cycle progression in breast cancer cells. Herein, expression of proteins in breast tissues was studied by immunohistochemistry and results were analyzed statistically to obtain semi-quantitative data. Biochemical and functional changes in BAD-overexpressing MCF7 breast cancer cells were evaluated using PCR, reporter assays, western blotting, ELISA and extracellular matrix invasion assays. Compared to normal tissues, Grade II breast cancers expressed low total/phosphorylated forms of BAD in both cytoplasmic and nuclear compartments. BAD overexpression ...

Chronic Exposure To Combined Carcinogens Enhances Breast Cell Carcinogenesis With Mesenchymal And Stem-Like Cell Properties., Lenora Pluchino, Hwa-Chain Wang

Lenora A. Pluchino, Ph.D.

Breast cancer is the most common type of cancer affecting women in North America and Europe. More than 85% of breast cancers are sporadic and attributable to long-term exposure to small quantities of multiple carcinogens. To understand how multiple carcinogens act together to induce cellular carcinogenesis, we studied the activity of environmental carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and benzo[a]pyrene (B[a]P), and dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) using our breast cell carcinogenesis model. Our study revealed, for the first time, that combined NNK and B[a]P enhanced breast cell carcinogenesis chronically induced ...

List Of Economics Department Pamphlets, Penny Stover

Economics Pamphlet Series

No abstract provided.

Developmental Ethanol Exposure Leads To Dysregulation Of Lipid Metabolism And Oxidative Stress In Drosophila, Theresa Logan-Garbisch, Anthony Bortolazzo, Peter Luu, Audrey Ford, David Do, Payam Khodabakhshi, Rachael L. French

Rachael L. French

Reactive Oxygen Species-Mediated Breast Cell Carcinogenesis Enhanced By Multiple Carcinogens And Intervened By Dietary Ergosterol And Mimosine, Lenora Pluchino, Amethyst Liu, Hwa-Chain Robert Wang

Lenora A. Pluchino, Ph.D.

Most breast cancers occur sporadically due to long-term exposure to low-dose carcinogens in the diet and the environment. Specifically, smoke, polluted air, and high temperature-cooked meats comprise multiple carcinogens, such as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), benzo[α]pyrene (B[α]P), and 2-amino-1-methyl-6-phenylimidazo[4,5–b]pyridine (PhIP). We sought to determine if these carcinogens act together to induce breast cell carcinogenesis, and if so, whether non-cytotoxic dietary agents could intervene. We demonstrated that co-exposure to physiologically-achievable doses of NNK, B[α]P, and PhIP (NBP) holistically enhanced initiation and progression of breast cell carcinogenesis. Reactive oxygen species ...

Engaging Youth In Lifelong Outdoor Adventure Activities Through A Nontraditional Public School Physical Education Program, Keri Schwab, Daniel L. Dustin

Keri Schwab

Engaging Youth in Lifelong Outdoor Adventure Activities through a Nontraditional Public School Physical Education Program

A Framework For Organizing Cancer-Related Variations From Existing Databases, Publications And Ngs Data Using A High-Performance Integrated Virtual Environment (Hive), Tsung-Jung Wu, Amirhossein Shamsaddini, Yang Pan, Krista Smith, Daniel J. Chrichton, Vahan Simonyan, Raja Mazumder

Biochemistry and Molecular Medicine Faculty Publications

Years of sequence feature curation by UniProtKB/Swiss-Prot, PIR-PSD, NCBI-CDD, RefSeq and other database biocurators has led to a rich repository of information on functional sites of genes and proteins. This information along with variation-related annotation can be used to scan human short sequence reads from next-generation sequencing (NGS) pipelines for presence of non-synonymous single-nucleotide variations (nsSNVs) that affect functional sites. This and similar workflows are becoming more important because thousands of NGS data sets are being made available through projects such as The Cancer Genome Atlas (TCGA), and researchers want to evaluate their biomarkers in genomic data. BioMuta, an ...

Tsu Faculty Publication Database, David Owerbach

David Owerbach

THE TSU faculty publication database is for the years 2012-2014. The database was constructed by the Office of Research and was last updated on November 20, 2014.

A Small Subset Of Fruitless Subesophageal Neurons Modulate Early Courtship In Drosophila, David H. Tran, Geoffrey W. Meissner, Rachael L. French, Bruce S. Baker

Rachael L. French

Longitudinal Transcriptomic Dysregulation In The Peripheral Blood Of Transgenic Huntington’S Disease Monkeys, Jannet Kocerha, Yuhong Liu, David Willoughby, Kumaravel Chidamparam, Joseph Benito, Kate Nelson, Yan Xu, Tim Chi, Heidi Engelhardt, Sean Moran, Shang-Hsun Yang, Shi-Hua Li, Xiao-Jiang Li, Katherine Larkin, Adam Neumann, Heather Banta, Jinjing Yang, Anthony W. S. Chan

Jannet Kocerha

Background: Huntington’s Disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the polyglutamine (polyQ) region of the Huntingtin (HTT) gene. The clinical features of HD are characterized by cognitive, psychological, and motor deficits. Molecular instability, a core component in neurological disease progression, can be comprehensively evaluated through longitudinal transcriptomic profiling. Development of animal models amenable to longitudinal examination enables distinct disease-associated mechanisms to be identified.

Results: Here we report the first longitudinal study of transgenic monkeys with genomic integration of various lengths of the human HTT gene and a range of polyQ repeats. With this unique ...

Department Of Economics Publication List 2012, Penny Stover

Economics Pamphlet Series

This compilation lists works authored by Department of Economics faculty members and other staff working on projects funded through the Department of Economics. Publications resulting from their research and academic activities are indexed by author at the end of this pamphlet for easy access by the public. The articles were published between January 1, 2012 and December 31, 2012, except for those works printed in italics which have been accepted for publication but not actually printed as of December 31, 2012.

Physical Properties Of Yogurt Fortified With Various Commercial Whey Protein Concentrates, Isabelle Sodini, John Montella, Phillip S. Tong

Phillip S. Tong

The effects of whey protein concentrates on physical and rheological properties of yogurt were studied. Five commercial whey protein concentrates (340 g kg−1 protein nominal) were used to fortify milk to 45 g protein kg−1. Fermentation was performed with two different starters (ropy and non-ropy). Resulting yogurts were compared with a control yogurt enriched with skim milk powder. The water-holding capacity of the yogurt fortified with skim milk powder was 500 g kg−1 and ranged from 600 to 638 g kg−1 when fortified with whey protein concentrates. Significant rheological differences have been noticed between the yogurts ...

Advances In Profiling Of Noncoding Rnas In Neurological Disease, Murray J. Cairns, Jannet Kocerha

Jannet Kocerha

No abstract provided.

Patent Landscape Of Helminth Vaccines And Related Technologies, Jon R. Cavicchi, Stanley P. Kowalski, John Schroeder, Rayna Burke, Jillian Michaud-King

Law Faculty Scholarship

Executive Summary This report focuses on patent landscape analysis of technologies related to vaccines targeting parasitic worms, also known as helminths. These technologies include methods of formulating vaccines, methods of producing of subunits, the composition of complete vaccines, and other technologies that have the potential to aid in a global response to this pathogen. The purpose of this patent landscape study was to search, identify, and categorize patent documents that are relevant to the development of vaccines that can efficiently promote the development of protective immunity against helminths. The search strategy used keywords which the team felt would be general ...

Expression Of Fused In Sarcoma Mutations In Mice Recapitulates The Neuropathology Of Fus Proteinopathies And Provides Insight Into Disease Pathogenesis, Christophe Verbeeck, Mariely Dejesus-Hernandez, Carolina Ceballos-Diaz, Jannet Kocerha, Todd Golde, Pritam Das, Rosa Rademakers, Dennis W. Dickson, Thomas Kukar

Jannet Kocerha

Background: Mutations in the gene encoding the RNA-binding protein fused in sarcoma (FUS) can cause familial and sporadic amyotrophic lateral sclerosis (ALS) and rarely frontotemproal dementia (FTD). FUS accumulates in neuronal cytoplasmic inclusions (NCIs) in ALS patients with FUS mutations. FUS is also a major pathologic marker for a group of less common forms of frontotemporal lobar degeneration (FTLD), which includes atypical FTLD with ubiquitinated inclusions (aFTLD-U), neuronal intermediate filament inclusion disease (NIFID) and basophilic inclusion body disease (BIBD). These diseases are now called FUS proteinopathies, because they share this disease marker. It is unknown how FUS mutations cause disease ...

G73-73 Sweet Potatoes (Revised June 1992), R.E. Neild, Laurie Hodges

Laurie Hodges

Varieties, requirements and culture, harvesting and storage of sweet potatoes. The sweet potato, a member of the morning glory plant family, is native to tropical America. It is an important food plant in warmer regions of the world and is adapted to southeastern Nebraska. Sweet potatoes may be boiled, baked, fried, or candied. They have high food value. Varieties with deeply yellow colored roots are a good source of vitamin A.

Nf97-344 Weights And Measures Guidelines For Sales At Farmers' Markets, Roadside Stands And Other Commercial Outlets, Laurie Hodges

Laurie Hodges

This NebFact focuses on the sale of fresh produce at farmers' markets, roadside stands, and other seasonal outlets.

Nf91-50 Bee Pollination Of Cucurbit Crops, Laurie Hodges, Fred Baxendale

Laurie Hodges

This NebFact discusses bee pollination of cucurbit crops.

G00-1778 Field Windbreaks, James Brandle, Laurie Hodges

Laurie Hodges

gricultural producers face many challenges as they try to balance efficient production systems with increasing environmental demands. For these systems to be successful, they must optimize the balance between inputs and final production. Field windbreaks are one way to increase yields while at the same time reducing inputs and improving both environmental quality and production efficiency. Windbreaks reduce wind speed and alter the microclimate in sheltered areas. Field windbreaks reduce wind erosion and the damage to crops caused by wind-blown soil. They improve water use efficiency, reduce risks associated with drought, and manage blowing snow.

Field windbreaks provide positive economic ...

Nf92-69 Selected Vegetable Cultivars For Nebraska, Susan Schoneweis, Laurie Hodges

Laurie Hodges

This NebFact provides information about cultivars of garden vegetables available to grow in Nebraska.

G90-993 Basic Cultural Practices For Commercial Production Of Green (Snap) Beans, Laurie Hodges

Laurie Hodges

This NebGuide discusses cultivar selection, production, pest management and packing of commercial green beans. Cultivars Selection of cultivars depends on intended use or market. "Processor" cultivars are low in fiber and are best for home garden and roadside markets as well as processing. These include the various Bush Blue Lake selections (BBL 47, BBL 92, BBL 274) and others such as Early Gallatin, Eagle, Slenderwhite, Labrador, Flo, and Peak. The "fresh market" or "shipping" beans have high fiber to maintain quality during long distance shipping. These include Strike, Podsquad, Blazer, Triumph, Atlantic, Gatorgreen, Greencrop, Sprite, and many others. Cultivars with ...

Nf91-43 Blossom End Rot In Tomatoes, Laurie Hodges, Don Steinegger

Laurie Hodges

This NebFact discusses the causes, prevention and treatment of blossom end rot in tomatoes.