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Articles 1 - 9 of 9
Full-Text Articles in Life Sciences
Bridging The Gap Between Life Insurer And Consumer In The Genetic Testing Era: The Rf Proposal, Christopher M. Keefer
Bridging The Gap Between Life Insurer And Consumer In The Genetic Testing Era: The Rf Proposal, Christopher M. Keefer
Indiana Law Journal
No abstract provided.
Phenotypic Expressions Of Ccr5-Δ32/Δ32 Homozygosity, Giang T. Nguyen, Mary Carrington, Judith A. Beeler, Michael Dean, Louis M. Aledort, Philip M. Blatt, Alan R. Cohen, Donna Dimichele, M. Elaine Eyster, Craig M. Kessler, Barbara Konkle, Cindy Leissinger, Naomi Luban, Stephen J. O'Brien, James J. Goedert, Thomas R. O'Brien
Phenotypic Expressions Of Ccr5-Δ32/Δ32 Homozygosity, Giang T. Nguyen, Mary Carrington, Judith A. Beeler, Michael Dean, Louis M. Aledort, Philip M. Blatt, Alan R. Cohen, Donna Dimichele, M. Elaine Eyster, Craig M. Kessler, Barbara Konkle, Cindy Leissinger, Naomi Luban, Stephen J. O'Brien, James J. Goedert, Thomas R. O'Brien
Biology Faculty Articles
Objective: As blockade of CC-chemokine receptor 5 (CCR5) has been proposed as therapy for HIV-1, we examined whether the CCR5-Δ32/Δ32 homozygous genotype has phenotypic expressions other than those related to HIV-1.
Design: Study subjects were white homosexual men or men with hemophilia who were not infected with HIV-1. In this study, 15 CCR5-Δ32/Δ32 homozygotes were compared with 201 CCR5 wild-type (+/+) subjects for a wide range of clinical conditions and laboratory assay results ascertained during prospective cohort studies and routine clinical care. CCR5-Δ32 genotype was determined by polymerase chain reaction, followed by single-stranded conformational polymorphism analysis.
Results: …
Implications Of Cloning For Breed Improvement Strategies: Are Traditional Methods Of Animal Improvement Obsolete?, L. Dale Van Vleck
Implications Of Cloning For Breed Improvement Strategies: Are Traditional Methods Of Animal Improvement Obsolete?, L. Dale Van Vleck
Department of Animal Science: Faculty Publications
Can the optimum animal be defined? Will that definition change over time, by location, by market demand? First, assume what may be impossible, that the perfect animal can be defined or that only a limited number of definitions of “perfect” are needed. Then, can the “perfect” animal to match a definition be found? Suppose such an animal is found. Then the question to be answered before trying to clone as a method of genetic improvement becomes “Is the animal perfect because of phenotype or genotype?” In other words, the P = G + E problem exists, which requires traditional methods …
Genotypic Expression At Different Ages: Ii. Wool Traits Of Sheep, H. Okut, C. M. Bromley, L. Dale Van Vleck, G. D. Snowder
Genotypic Expression At Different Ages: Ii. Wool Traits Of Sheep, H. Okut, C. M. Bromley, L. Dale Van Vleck, G. D. Snowder
Department of Animal Science: Faculty Publications
Genetic parameters for wool traits for Columbia, Polypay, Rambouillet, and Targhee breeds of sheep were estimated with single- and multiple-trait analyses using REML with animal models. Traits considered were fleece grade, fleece weight, and staple length. Total number of observations ranged from 11,673 to 34,746 for fleece grade and fleece weight and from 3,500 to 11,641 for staple length for the four breeds. For single-trait analyses, data were divided by age of ewe: young ages (age of 1 yr), middle ages (ages of 2 and 3 yr), and older ages (age greater than 3 yr). Heritability estimates averaged over breeds …
Genotypic Expression At Different Ages: I. Prolificacy Traits Of Sheep, H. Okut, C. M. Bromley, L. Dale Van Vleck, G. D. Snowder
Genotypic Expression At Different Ages: I. Prolificacy Traits Of Sheep, H. Okut, C. M. Bromley, L. Dale Van Vleck, G. D. Snowder
Department of Animal Science: Faculty Publications
Genetic parameters for prolificacy traits for Columbia (COLU), Polypay (POLY), Rambouillet (RAMB), and Targhee (TARG) breeds of sheep were estimated with REML using animal models. Traits were number of live births (LAB), litter size at birth (LSB) and weaning (LSW), and litter weight weaned (LWW). Numbers of observations ranged from 5,140 to 7,095 for prolificacy traits and from 5,101 to 8,973 for litter weight weaned for the four breeds. For single-trait analyses, ewes were classified as young (1 yr old), middle-aged (2 and 3 yr old), or older (> 3 yr old). After single-trait analyses, three-trait analyses were done for …
Trends. Altered States And Genetically Altered Products: Psychological Crisis At Cartagena, Ibpp Editor
Trends. Altered States And Genetically Altered Products: Psychological Crisis At Cartagena, Ibpp Editor
International Bulletin of Political Psychology
The author discusses the first comprehensive attempt to develop a global treaty that would regulate commerce in genetically altered products.
Trends. Evolutionary Theories, Iceland, And An Opportunity It Can't Refuse, Ibpp Editor
Trends. Evolutionary Theories, Iceland, And An Opportunity It Can't Refuse, Ibpp Editor
International Bulletin of Political Psychology
The author discusses a major Swiss pharmaceutical company that plans on investing in Icelandic deoxyribonucleic acid (DNA).
Cooperative Binding Of Heat Shock Factor To The Yeast Hsp82 Promoter In Vivo And In Vitro, Alexander M. Erkine, Serena F. Magrogan, Edward A. Sekinger, David S. Gross
Cooperative Binding Of Heat Shock Factor To The Yeast Hsp82 Promoter In Vivo And In Vitro, Alexander M. Erkine, Serena F. Magrogan, Edward A. Sekinger, David S. Gross
Scholarship and Professional Work – COPHS
revious work has shown that heat shock factor (HSF) plays a central role in remodeling the chromatin structure of the yeastHSP82 promoter via constitutive interactions with its high-affinity binding site, heat shock element 1 (HSE1). The HSF-HSE1 interaction is also critical for stimulating both basal (noninduced) and induced transcription. By contrast, the function of the adjacent, inducibly occupied HSE2 and -3 is unknown. In this study, we examined the consequences of mutations in HSE1, HSE2, and HSE3 on HSF binding and transactivation. We provide evidence that in vivo, HSF binds to these three sites cooperatively. This cooperativity is seen …
1999 Nebraska Swine Report, Duane E. Reese
1999 Nebraska Swine Report, Duane E. Reese
University of Nebraska-Lincoln Extension: Historical Materials
This publication was prepared by the staff in Animal Science and cooperating Departments for use in Extension, Teaching and Research programs. It deals with the results that were done in reproduction, genetics, breeding, health, nutrition, economics and housing of swine.