Life Sciences Commons^™

Interaction Of Fish Aryl Hydrocarbon Receptor Paralogs (Ahr1 And Ahr2) With The Retinoblastoma Protein, Rebeka Merson, Sibel Karchner, Mark Hahn

Rebeka Rand Merson

The aryl hydrocarbon receptor (AHR) mediates the toxic effects of 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) and related compounds. In some mammalian cell lines, TCDD induces G1 cell cycle arrest, which depends on an interaction between the AHR and the retinoblastoma tumor suppressor (RB). Mammals possess one AHR, whereas fishes possess two or more AHR paralogs that differ in the domains important for AHR-RB interactions in mammals. To test the hypothesis that fish AHR paralogs differ in their ability to interact with RB, we cloned RB cDNA from Atlantic killifish, Fundulus heteroclitus, and studied the interactions of killifish RB protein with killifish AHR1 and …

The Effects Of Dependent Infants On The Social Behavior Of Mantled Howler Monkeys (Alouatta Palliate), Keziah Katz

Honors Theses and Capstones

Six weeks of observation on eight groups of wild mantled howler monkeys revealed that the presence of a dependent infant alters the frequency of social interactions between a female with an infant and other adult monkeys. Males preferred to spend time with females without infants but still spent more time with females with infants than with males. Females without infants spent significantly less time with females with infants than with males or other females without infants and females with infants decreased their frequency of social interaction overall without preference for males, females or other females with infants.

Cloning And Characterization Of The Cell Wall Acting Enzyme Cd1034 From The Pathogen Clostridium Difficile, Zachary Suter

Honors Projects in Science and Technology

The manifestation of multidrug resistance in bacteria over the past several decades has resulted in one of the foremost challenges in the management of infectious diseases. The question arises, “How do we address this growing problem?” One solution to stem the growing rise in antimicrobial resistance is to investigate new targets, while another approach is to re-examine classical antibacterial targets with a fresh perspective. The aim of this paper is to begin the process of antibacterial development for the pathogen Clostridium difficile by characterizing the cell wall acting glucosaminidase CD1034. It is inunderstanding how CD1034 functions biochemically that it can …

Effects Of Hypoxia-Ischemia And Anti-Inflammatory Prophylactic Treatment On Cortical And Hippocampal Volumes In The Developing Rat Brain, Llian Mabardi

Honors Projects

Very low body weight as a result of premature birth is a common problem all around the world. Many of these infants have medical issues that arise as a direct result of their very low body weight. One of the biggest issues is a lack of oxygen, which is also known as hypoxia. Hypoxia and ischemia (lack of blood flow) are a problem at any age, but they can be especially devastating to infants who have not undergone critical periods of brain development. Hypoxia-ischemia (or HI) can cause problems that start as inflammation and end with large-scale cell death in …

Library Impact Statement For Nrs/Bio 417 Herpetology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for NRU/BIO 417 Herpetology new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Nancy E. Karraker.

Library Impact Statement For Nrs/Bio 517 Herpetology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for NRS/BIO 517 Herpetology. No new library resources are needed to support this course. Responding library faculty member: Micael A. Cerbo II. Requesting faculty member: Nancy E. Karraker.

Reducing False-Positive Prediction Of Minimotifs With A Genetic Interaction Filter, Jerlin Camilus Merlin, Sanguthevar Rajasekaran, Tian Mi, Martin Schiller

Life Sciences Faculty Research

Background

Minimotifs are short contiguous peptide sequences in proteins that have known functions. At its simplest level, the minimotif sequence is present in a source protein and has an activity relationship with a target, most of which are proteins. While many scientists routinely investigate new minimotif functions in proteins, the major web-based discovery tools have a high rate of false-positive prediction. Any new approach that reduces false-positives will be of great help to biologists.

Methods and Findings

We have built three filters that use genetic interactions to reduce false-positive minimotif predictions. The basic filter identifies those minimotifs where the source/target …

Library Impact Statement For Bio 501 Advanced Scientific Ethics, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 501 Advanced Scientific Ethics new course proposal. No new resources are required to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Chris Lane.

Library Impact Statement For Bio 502 Advanced Scientific Communication, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 502 Advanced Scientific Communication new course proposal. No new resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Chris Lane.

Library Impact Statement For Bio 553 Regulatory Processes In Eucaryotic Cells, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 553 Regulatory Processes in Eucaryotic Cells new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Joanna Norris.

Biology And Pathogenesis Of Acanthamoeba., Ruqaiyyah Siddiqui, Naveed Ahmed Khan

Department of Biological & Biomedical Sciences

Acanthamoeba is a free-living protist pathogen, capable of causing a blinding keratitis and fatal granulomatous encephalitis. The factors that contribute to Acanthamoeba infections include parasite biology, genetic diversity, environmental spread and host susceptibility, and are highlighted together with potential therapeutic and preventative measures. The use of Acanthamoeba in the study of cellular differentiation mechanisms, motility and phagocytosis, bacterial pathogenesis and evolutionary processes makes it an attractive model organism. There is a significant emphasis on Acanthamoeba as a Trojan horse of other microbes including viral, bacterial, protists and yeast pathogens.

Library Impact Statement For Bio 485x Salt Marsh Ecology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 485X Salt Marsh Ecology new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Serena Moseman-Valtierra.

Library Impact Statement For Bio 585x Salt Marsh Ecology, Michael A. Cerbo Ii

Library Impact Statements

Library Impact Statement for BIO 585X Salt Marsh Ecology new course proposal. No new library resources are needed to support this course. Responding library faculty member: Michael A. Cerbo II. Requesting faculty member: Serena Moseman-Valtierra.

Quantifying The Impacts Of Oyster Reef Restoration On Oyster Coverage, Wave Attenuation And Seagrass Fragment Retention In Mosquito Lagoon, Florida, Stephanie Garvis

Electronic Theses and Dissertations

The goal of this project was to determine the effects of oyster reef restoration on oyster coverage, wave height dissipation and seagrass recruitment. First, to assess the current versus historical coverage of natural, dead and restored oyster reefs within Mosquito Lagoon, aerial photographs from 2009, provided by Saint Johns River Water Management District, were digitized using ArcGIS software. Live reefs, restored reefs and dead reefs were screen digitized using a reef ‘signature’ in order to estimate the area of each type of reef. The 2009 maps were used as a guide to digitizing the historical aerial photographs (1943, 1951, 1967, …

It’S My Body: The Biomedical Ethics Of Cell And Organ Harvest, Christina Perri

Common Reading Essay Contest Winners

First Place

2b: "Copy Of Carbon Dioxide Data Illinois Coal", U.S. Energy Information Administration

Ecosystem Disruption & Climate Change

No abstract provided.

2b: "Copy Of Carbon Dioxide Data Illinois Petroleum Products", U.S. Energy Information Administration

Ecosystem Disruption & Climate Change

No abstract provided.

2b: "Copy Of Carbon Dioxide Data Illinois Natural Gas", U.S. Energy Information Administration

Ecosystem Disruption & Climate Change

No abstract provided.

2b: "Copy Of Carbon Dioxide Data Illinois Totals", U.S. Energy Information Administration

Ecosystem Disruption & Climate Change

No abstract provided.

Full Issue: Volume 6, Number 1

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

Full Issue: Volume 5, Issue 2

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

Chemotherapy: The Physiological Cost Of A Cure, Megan Ellis

A with Honors Projects

This project focuses on the common long term side effects of cancer treatments, apart from cure. In addition to physiological function changes, it focuses on the chemical composition of chemotherapy drugs.

Cancer And You, Diah-Aldeen Judeh

A with Honors Projects

This project discusses ways a person can identify cancer and what to do if cancer is present.

A Comparison Of Water Potential And Mechanical Strength Of Tip And Base Leaves In Heteromeles Arbutifolia, Aaron Tsai, James Maynard

Featured Research

Heteromeles arbutifolia, commonly known as, Hollywood, is a plant that is extremely common in the California Chaparral ecosystem. It was observed that with Hollywood, the leaves grow on the tips of the branches predominantly. However, there are leaves that grow on the base of the branches that appear to be equally as healthy. The purpose of this investigation was to determine whether the leaves that grow at the tips of the branches or at the base of the branches were better suited to benefit the rest of the plant. Our hypothesis was that the leaves at the tips of the …

The Effects Of Water Stress On Datura Wrightii, Tony Festa, Kristin Lapointe, Sara Tandon

Featured Research

The Santa Monica Mountains are home to a unique Mediterranean type ecosystem. Due to the effects of global warming and human disruption, the native species are beginning to decrease in population. It is imperative to observe and study the native species in order to preserve the local plant and animal life. This project focuses on the native flower Datura wrightii, specifically the causes of the opening and closing of its flowers. For Datura wrightii to be pollinated, it must be open. The results of this project will help to educate the public on how to sustain an environment in which …

The Differences In Vegetation Type On North And South-Facing Slopes, Andrew Villablanca, Katherine Mccabe, Daniel Galuhn

Featured Research

Our project investigated the relationship between climate change and vegetation type conversion in the Santa Monica Mountains on north and south facing slopes. Our hypothesis is that with a shift in climate towards dryer, hotter, and longer summers, and shorter and dryer winters, we will see a shift in the density of native chaparral in the Santa Monica mountains, and possibly an influx of non-native species. We tested this hypothesis by choosing three study sites that were on north/south ridgelines to simulate a dryer, harsher climate (south) and a more temperate climate (north). Using the point-quarter method to measure the …

Mechanical Strength And Hydration Level Of Heteromeles Arbutifola And Eriogonium Cinerium, Erin Hayes, Allison Naasz, Ariel Mangum

Featured Research

The purpose of this study was to explore the hydration levels and mechanical strength of two species native to the same area: the dry Mediterranean region of the Santa Monica Mountains. The plants in this area must make adaptations to dry and arid climates, and We will compare how they stack up against each other in terms of drought resistance. Using Hollywood (heteromeles arbutifola) and Buckwheat (Eriogonium cinerium) we studied the different hydration levels and mechanical strengths and compared them. Both H. Arbutifola and the E. Cinerium are expected to mechanically stronger when hydrated.. We also expect the H. Arbutifola …

Exploring The Hydration Levels Of Malosma Laurina At Different Elevations On A Man-Made Trail, Eric S. Taylor, Brad J. Anderson, Brandon E. Stites

Featured Research

The purpose of this study is to examine the water potential of Malosma laurina at different elevations of a man made trail in the chapparal of the Santa Monica Mountains. Chaparral in the Santa Monica Mountains have been depleted because of human involvement effecting the chaparral ecosystem. Fire breaks and man made trails are a few of the major causes of the rapidly changing ecosystem and continues to cause stress among the plants. We are testing the effect that man made trails have on the water potential of Malosma laurina. This was measured by taking samples of Malosma laurina at …

Stem Mechanical Strength In Thinned Versus Non-Thinned Ceanothus Spinosus, Ksp, David J. Kang, Hannah Y. Choe, Melinda L. Marchiano

Featured Research

What effect does the thinning of chaparral around building structures have on plant health? More specifically, does the thinning of Ceanothus spinosus influence mechanical strength? The ability of our native chaparral to withstand environmental factors, such as the Santa Ana winds, and overall health is directly related to plant strength. Seeking to answer these questions, we hypothesized that a difference in water potential between thinned and non-thinned chaparral affects the stem mechanical strength of the plants.We believed that thinned C. spinosus due to greater hydration will be mechanically stronger than non-thinned chaparral.The knowledge of what helps chaparral to be stronger …

Lifelines Winter 2012, Southern Adventist University

Lifelines - Biology Department Newsletter

The Winter 2012 issue of Lifelines contains articles on Southern's ancient DNA project, the Pre-dental club, and a pictorial directory of the 2012 biology and allied health graduates.