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Full-Text Articles in Life Sciences
Articulating The Importance Of Broader Relevance In Cures: From Definition To Actualization, Nikki T. Donegan
Articulating The Importance Of Broader Relevance In Cures: From Definition To Actualization, Nikki T. Donegan
Open Access Theses & Dissertations
Course-based undergraduate research experiences (CUREs) have emerged as a means to foster student' scientific reasoning, promote positive attitudes and motivations toward research, and increase persistence in the science, technology, engineering, and mathematics (STEM) fields. In contrast to prescriptive laboratories, students enrolled in CUREs employ techniques and skills to collaboratively and iteratively address novel questions of broad relevance to audiences beyond the scope of the course itself. While many of the core components of CUREs are perceived to be relatively straightforward, definitionally-speaking, this latter dimension of broader relevance has, in contrast, remained largely ill-defined. In the series of studies presented herein, …
Molecular Mechanism Of Neurodegeneration Induced By 4-Nonylphenol, Michelle Alejandra Aranda
Molecular Mechanism Of Neurodegeneration Induced By 4-Nonylphenol, Michelle Alejandra Aranda
Open Access Theses & Dissertations
Neurodegeneration, a progressive loss of nerve cells, occurs in many neurological disorders, including Alzheimer's disease (AD) and Parkinson's diseases (PD), as well as in dementia. The pathogenesis of these diseases is unknown, and recent evidence suggests that environmental factors, which act as endocrine-disrupting compounds (EDCs) could play a significant role in developing the disease process. 4-Nonylphenol (4-NP), an EDC, and a ubiquitous environmental toxin has been shown to affect brain development and may cause neurodegeneration. 4-NP is produced in large quantities in the U.S. and used as raw materials for making detergents, pesticides, plastics, paints, cosmetics, rubber, and other industrial/household …