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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2019

Biology

Longwood University

Articles 1 - 3 of 3

Full-Text Articles in Life Sciences

Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall Apr 2019

Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall

Spring Showcase for Research and Creative Inquiry

Investigating the effects of cancer mutations on the activity of p300


Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek Apr 2019

Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek

Spring Showcase for Research and Creative Inquiry

Flavonoids are natural compounds found in dietary elements such as soy, grains, and vegetables that have the potential to bind to the estrogen receptor. Activation of the estrogen receptor drives myeloid derived suppressor cell (MDSC) accumulation, cells that increase during cancer, inflammation, and infection. In this study, we are investigating specific flavonoids, such as epigallocatechin-3-gallate (EGCG), kaempferol, naringenin, daidzein, and genistein, for their ability to mimic estrogen. After examination, we expect that MDSC differentiation will decrease upon treatment of the chosen flavonoids, leading to reduced carcinogenic effects.


The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter Apr 2019

The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter

Spring Showcase for Research and Creative Inquiry

A research proposal for a novel immunotherapy for treating ovarian cancer.