Life Sciences Commons^™

Biology Of Sharks And Their Relatives Bio 422, Joanna Burkhardt

Library Impact Statements

No abstract provided.

The Cancer Stem Cell Marker Gsk3b, A Gene Involved In Oxidative Stress, Modulates Chemoresistance In Ovarian Cancer, Noelle L. Cutter Ph.D., Julia Fiederlein, Brianna Mcnulty, Cassandra Greco, Kimberly Doyle

Faculty Works: Biology, Chemistry, and Environmental Studies

The leading cause of death from gynecologic malignancies is epithelial ovarian cancer. These tumors are comprised of a highly heterogeneous population of cells, of which only a small subset of stem-like cells possess the ability to regenerate tumors in vivo. These cancer stem cells (CSCs) represent a significant clinical challenge as they are resistant to conventional cancer therapies and play essential roles in metastasis and tumor relapse. While chemotherapy is the preferred treatment modality, chemoresistance severely limits treatment success. It has been hypothesized that cancer stem cells are at the root of this problem. Their ability to self-renew and proliferate …

Mammal Species Inventory Using Various Trapping Methods In Zone 4 Of Billy Barquedier National Park, Belize During Rainy Season, Mersady Redding

Animal Science Undergraduate Honors Theses

Belize is a small country, but it is extremely ecologically diverse. Based on the few studies conducted in Belize, the abundance of mammals is low but diversity is high. Particular findings note the number and identity of species differed between four sites in the Maya Mountains of Belize, indicating that a data set from a single site is not representative of the Neotropical region. Insufficient data is available to estimate current species richness of many areas in Belize, including Billy Barquedier National Park (BBNP). The objective of this study was to explore trapping and documentation methods of terrestrial mammals in …

Undergraduate Research Science: Principles And Practice Bio 200, Michael Cerbo

Library Impact Statements

No abstract provided.

Titration Of A Newtown Creek Environmental Water Sample To Determine The Amount Of Chloride Ions [Chemistry], Kevin Mark

Open Educational Resources

Main Course Learning Objectives:

The General Chemistry 1 (SCC 201) course has multiple course learning objectives, which articulate key introductory chemistry concepts that all STEM students should possess. In particular, the Newtown Creek titration experiment aligns with SCC 201 learning objectives of:

1. Demonstrate an appreciation of the role of chemistry in various aspects of life
2. Perform basic laboratory skills such as the proper execution of titration techniques
3. Describe and explain the fundamental chemistry concept of solution concentration
4. Analyze and represent experimental data in tables and graphs, interpret experimental results and write laboratory reports

In the SCC 201 laboratory, students are …

Human Biology Oer, Bio 1100, Course Outline, Tatiana Voza

Open Educational Resources

This course will include selected biological concepts, including the chemical basis of life, cell structure and division, a broad survey of the major systems of the human body with a special emphasis on human health disease, human evolution and ecology. This course should provide students who do not plan to continue in the sciences or pre-health programs with a working knowledge of life science that will be useful in making informed decisions on health and the environment

Principles Of Biology I & Ii (Atlm), Candice Chatman, Alvin Harmon, Deon O'Bryant, Stephen Klusza

Biological Sciences Grants Collections

This Grants Collection for Principles of Biology I & II was created under a Round Twelve ALG Textbook Transformation Grant.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials:

• Linked Syllabus
• Initial Proposal
• Final Report

Artful Nature And The Legacy Of Maria Sibylla Merian, Emily N. Roush, Shannon R. Zeltmann, Felicia M. Else, Kay Etheridge, Shannon Egan

Schmucker Art Catalogs

The exhibition Artful Nature and the Legacy of Maria Sibylla Merian celebrates the skills and influences of a remarkable woman from seventeenth-century Europe. Curated by Emily Roush ’21 and Shannon Zeltmann ’21 with the guidance of Professors Kay Etheridge (Biology) and Felicia Else (Art History), Emily and Shannon selected the prints, organized them into categories, and carried out research on them, much of which was relatively obscure and would have been challenging even for graduate students.

Maria Sibylla Merian lived and worked in a time of vibrant intersections of art and science in Europe. Her images of insects and plants …

Reading Guides For Openstax Concepts Of Biology, Kathryn Dye

Biological Sciences Ancillary Materials

This set of reading guides for OpenStax Concepts of Biology (https://openstax.org/details/books/concepts-biology) was created under a Round Thirteen Mini-Grant for Ancillary Materials Creation and Revision.

These activity-focused guides cover the following chapters of the text:

• Chapter 1 - Introduction to Biology;
• Chapter 2 - Chemistry of Life;
• Chapter 4 - How Cells Obtain Energy;
• Chapter 5 - Photosynthesis

Lifelines Fall 2019, Southern Adventist University

Lifelines - Biology Department Newsletter

No abstract provided.

Biology Of Human Health And Disease Bio 482g, Michael Cerbo

Library Impact Statements

No abstract provided.

Biology Of Medicine Bio 481x, Michael Cerbo

Library Impact Statements

No abstract provided.

Nature And Nurture: How Our Genes And Environments Shape Our Lives Bio 440g, Michael Cerbo

Library Impact Statements

No abstract provided.

Darwin At The Drugstore? Testing The Biological Fitness Of Antibiotic Resistant Bacteria, Alan L. Gillen, Sarah Anderson

Alan L. Gillen

The issue of antibiotic resistance in bacteria is growing. For example, methicillin-resistant Staphylococcus aureus (MRSA) is a leading human pathogen. New strains of MRSA are resistant to methicillin and numerous other antibiotics, placing the patient in significant danger. Indeed, the Centers for Disease Control revealed in 2007 that the number of deaths due to MRSA exceeded that of AIDS in the United States. It is no wonder that antibiotic resistance is one of the most significant and important health care issues. The ability of bacterial pathogens to evade traditional antibiotics is faster than the drug makers’ ability to make new …

Electrostatically Localized Proton Bioenergetics: Better Understanding Membrane Potential, James Weifu Lee

Chemistry & Biochemistry Faculty Publications

In Mitchell's chemiosmotic theory, membrane potential Δψ was given as the electric potential difference across the membrane. However, its physical origin for membrane potential Δψ was not well explained. Using the Lee proton electrostatic localization model with a newly formulated equation for protonic motive force (pmf) that takes electrostatically localized protons into account, membrane potential has now been better understood as the voltage difference contributed by the localized surface charge density ([H-⁺_L] + ⁿΣ _i=1 [M⁽ⁱ⁺⁾_L]) at the liquid-membrane interface as in an electrostatically localized protons/cations-membrane-anions capacitor. That is, the origin of membrane …

A Rapid Viability And Drug‑Susceptibility Assay Utilizing Mycobacteriophage As An Indicator Of Drug Susceptibilities Of Anti‑Tb Drugs Against Mycobacterium Smegmatis Mc2 155, Gillian Catherine Crowley, Jim O'Mahony, Aidan Coffey, Riona G. Sayers, Paul D. Cotter

Department of Biological Sciences Publications

Background: A rapid in-house TM4 mycobacteriophage-based assay, to identify multidrug resistance against various anti-tuberculosis drugs, using the fast-growing Mycobacterium smegmatis mc² 155 in a microtiter plate format was evaluated, based on phage viability assays. Methods: A variety of parameters were optimized before the study including the minimum incubation time for the drugs, phage and M. smegmatis mc² 155 to be in contact. An increase in phage numbers over 2 h was indicative that M. smegmatis mc² 155 is resistant to the drugs under investigation, however when phage numbers remained static, M. smegmatis mc² 155 found to …

Do Stands Of Native Trees Harbor Different Invasive Species Than Stands Of Planted Pine?, Carly Mccameron, John Mccarthy, Dr. Kevin Geedey

Celebration of Learning

The most outstanding invasive species that can be found at Augustana’s Green Wing Environmental Laboratory are honeysuckle, buckthorn, multiflora rose, garlic mustard, autumn olive, and oriental bittersweet. These plants are not only disrupting the ecosystem at Green Wing, but they are doing it all over the country. The result of their disruption is that they have taken over entire habitats and left natural species with no way to compete for survival. To study this we used the line-point method as well as other forms of data collection to compare a non-native pine tree habitat to an area dominated by native …

Dna Methods To Understand Genetic Variation Of The Mola Mola Populations In And Near Cape Cod, Jessica Barros

Honors Program Theses and Projects

The ocean sunfish Mola mola is a frequent summer visitor to the waters off of Southeastern Massachusetts and Cape Cod. In late fall, water temperatures drop and some animals strand on area beaches. Stranded animals provide an easily available source of DNA to study the population genetics of this species with the specific goal to learn about genetic variation within and between individuals in this population. This study will continue to identify and characterize microsatellite repeat regions that will be used to study genetic variation. Four new microsatellite regions have been identified and amplified using polymerase chain reaction conditions that …

The Effects Of Meloidogyne Incognita On Jaz1, Jaz12, And Jaz13 Gene Expression In Arabidopsis, Emily Green

Honors Program Theses and Projects

Meloidogyne incognita, a root-knot nematode (RKN), poses a threat to the well-being of the global agricultural industry. These endoparasites rely on plant roots and drain nutrients from crops intended for human or livestock consumption. Root knot nematodes cost the agricultural industry billions of dollars in lost crops each year and threaten efforts to meet the growing demand for food. Though plants are susceptible to dangers, such as these parasites, many have evolved defense and/or repair mechanisms to compensate for this vulnerability. The goal of this research is to study one gene family involved in such defenses. Specifically, I studied the …

Bringing Science To Life In The Fifth-Grade Classroom Through Hands-On Learning, Kelly Gately

Honors Program Theses and Projects

Science helps provide insight into the unknown and provides an outlet for exploration of living things. Children are innately curious about how thing work, and they are eager to ask questions. Science is the perfect outlook for students to fully engage in their inquisitiveness, but yet, many classrooms are skipping over science lessons or choosing to heavily focus on other subjects, such as reading and writing. Science is often taught as an elective, integrated with other subjects or it is only focused on for a short period of time. Unfortunately, when this subject does receive attention, lessons are heavily text-book …

The Role Of Oxytocin On Social Behavior Associated With The Formation Of A Social Pair-Bond In The Socially Monogamous Convict Cichlid (Amatitlania Nigrofasciata), Christopher Garcia

Graduate Theses

The mechanisms for monogamy have evolved several times throughout history across various taxa in accordance with selective pressures. In vertebrates, monogamy is facilitated by the formation and the maintenance of social pair-bonds between mates. Social pair-bonds are a form of selective attachment that require complex neurobiological pathways in order to develop and continue. These neurobiological pathways are often regulated by neuroendocrine mechanisms, such as the release of the two neuroendocrine nonapeptides, oxytocin and arginine vasopressin, in specific parts of the brain or body. These neuroendocrine peptides play a big role in social and sexual behaviors. In prairie voles (Microtus ochrogaster) …

Pyy3-36 Efficacy Is Independent Of Photoperiod But Dependent On Time Of Day, Marissa Maroni

Honors Program Theses and Projects

Approximately 70% of Americans are overweight or obese and studies have shown that poverty-dense American counties are the most prone to obesity (Levine, 2011). Along with diet, the endogenous circadian rhythms have been found to be an important piece of human metabolic health. Circadian disruption in humans, such as jet-lag and shift work, have been linked to metabolic problems such as Type 2 Diabetes Mellitus and Metabolic Syndrome. Since circadian disruption affects many demographics including shift workers and routine business travelers it is imperative to understand the biological mechanism behind the relationship between circadian disruption and weight gain. One potential …

Advanced Cell And Molecular Biology I Cmb 501, Michael Cerbo

Library Impact Statements

No abstract provided.

Advanced Cell & Molecular Biology Ii Cmb 502, Michael Cerbo

Library Impact Statements

No abstract provided.

Law And Biology: Toward An Integrated Model Of Human Behavior, Owen D. Jones

Owen Jones

As first year law students unhappily discover, the meaning of "law" is frustratingly protean, shifting by usage and user. Depending on whom you ask, law is a system of rules, a body of precedents, a legislative enactment, a collection of norms, a process by which social goals are pursued, or some dynamic mixture of these. Law's principal purpose is to define and protect individual rights, to ensure public order, to resolve disputes, to redistribute wealth, to dispense justice, to prevent or compensate for injury, to optimize economic efficiency, or perhaps to do something else. And yet one thing is irreducibly …

On The Nature Of Norms: Biology, Morality, And The Disruption Of Order, Owen D. Jones

Owen Jones

This essay discusses the legal implications of bio-behavioral underpinnings to norms, morality, and economic order. It first discusses the recent book "The Great Disruption: Human Nature and the Reconstitution of Social Order," in which Francis Fukuyama explores the importance of evolved human nature to the reconstruction of social order and a thriving economy. It then addresses the extent to which we can usefully view law-relevant norms as products of evolutionary - as well as economic - processes.

Law And Behavioral Biology, Owen D. Jones, Timothy H. Goldsmith

Owen Jones

Society uses law to encourage people to behave differently than they would behave in the absence of law. This fundamental purpose makes law highly dependent on sound understandings of the multiple causes of human behavior. The better those understandings, the better law can achieve social goals with legal tools. In this Article, Professors Jones and Goldsmith argue that many long held understandings about where behavior comes from are rapidly obsolescing as a consequence of developments in the various fields constituting behavioral biology. By helping to refine law's understandings of behavior's causes, they argue, behavioral biology can help to improve law's …

Alpha Mangostin As A Chemoprotective Agent Via Activation Of The P53 Pathway For Breast Cancer, Vanessa Van Oost

Scholar Week 2016 - present

Breast carcinoma is the most frequently diagnosed cancer among women and causes over 400,000 deaths yearly worldwide. Current treatments such as chemotherapy are not selective for cancerous tissues but are destructive to normal tissues as well. This causes a range of side effects including pain, nausea, hair loss, weakness, and more. Inactivation of p53 is an almost universal mutation within human cancer cells. The ability to activate the p53 pathway which protects cells from tumor formation is lost in 50% of cancers. Due to the prevalence of this mutation, p53 is a uniquely valuable target for applied research. Alpha mangostin …

Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall

Spring Showcase for Research and Creative Inquiry

Investigating the effects of cancer mutations on the activity of p300

Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek

Spring Showcase for Research and Creative Inquiry

Flavonoids are natural compounds found in dietary elements such as soy, grains, and vegetables that have the potential to bind to the estrogen receptor. Activation of the estrogen receptor drives myeloid derived suppressor cell (MDSC) accumulation, cells that increase during cancer, inflammation, and infection. In this study, we are investigating specific flavonoids, such as epigallocatechin-3-gallate (EGCG), kaempferol, naringenin, daidzein, and genistein, for their ability to mimic estrogen. After examination, we expect that MDSC differentiation will decrease upon treatment of the chosen flavonoids, leading to reduced carcinogenic effects.