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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2014

Biology Faculty Publications

University of Kentucky

Limb

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Full-Text Articles in Life Sciences

Probability Of Regenerating A Normal Limb After Bite Injury In The Mexican Axolotl (Ambystoma Mexicanum), Sierra Thompson, Laura Muzinic, Christopher Muzinic, Matthew L. Niemiller, S. Randal Voss Jun 2014

Probability Of Regenerating A Normal Limb After Bite Injury In The Mexican Axolotl (Ambystoma Mexicanum), Sierra Thompson, Laura Muzinic, Christopher Muzinic, Matthew L. Niemiller, S. Randal Voss

Biology Faculty Publications

Multiple factors are thought to cause limb abnormalities in amphibian populations by altering processes of limb development and regeneration. We examined adult and juvenile axolotls (Ambystoma mexicanum) in the Ambystoma Genetic Stock Center (AGSC) for limb and digit abnormalities to investigate the probability of normal regeneration after bite injury. We observed that 80% of larval salamanders show evidence of bite injury at the time of transition from group housing to solitary housing. Among 717 adult axolotls that were surveyed, which included solitary-housed males and group-housed females, approximately half presented abnormalities, including examples of extra or missing digits and …