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Dopaminergic Tone Persistently Regulates Voltage-Gated Ion Current Densities Through The D1r-Pka Axis, Rna Polymerase Ii Transcription, Rnai, Mtorc1, And Translation, Wulf-Dieter C. Krenz, Anna R. Parker, Edmund William Rodgers, Deborah J. Baro
Dopaminergic Tone Persistently Regulates Voltage-Gated Ion Current Densities Through The D1r-Pka Axis, Rna Polymerase Ii Transcription, Rnai, Mtorc1, And Translation, Wulf-Dieter C. Krenz, Anna R. Parker, Edmund William Rodgers, Deborah J. Baro
Biology Faculty Publications
Long-term intrinsic and synaptic plasticity must be coordinated to ensure stability and flexibility in neuronal circuits. Coordination might be achieved through shared transduction components. Dopamine (DA) is a well-established participant in many forms of long-term synaptic plasticity. Recent work indicates that DA is also involved in both activity-dependent and -independent forms of long-term intrinsic plasticity. We previously examined DA-enabled long-term intrinsic plasticity in a single identified neuron. The lateral pyloric (LP) neuron is a component of the pyloric network in the crustacean stomatogastric nervous system (STNS). LP expresses type 1 DA receptors (D1Rs). A 1 h bath application of 5 …