Life Sciences Commons^™

Mechanism Of Triazolo-Benzodiazepine And Benzodiazepine Action In Anxiety And Depression: Behavioral Studies With Concomitant In Vivo Ca1 Hippocampal Norepinephrine And Serotonin Release Detection In The Behaving Animal, Patricia A. Broderick, Omotola Hope, Pierrot Jeannot

Publications and Research

1. Real time, in vivo microvoltammetric studies were performed, using miniature carbon-based sensors, to concurrently detect norepinephrine (NE) release and serotonin (5-HT) release, in 2 separate electrochemical signals, within CA₁ region of hippocampus in the freely moving and behaving, male, Sprague Dawley laboratory rat.

2. Concurrently, four parameters of open-field Behavior I.E. Ambulations, Rearing, Fine Movements and Central Ambulatory behavior (a measure of anxiety reduction behavior), were assayed by infrared photobeam detection.

3. Time course studies showed that the mechanism of action of the triazolobenzodiazepine (TBZD), adinazolam, (Deracyn®) is dramatically different from that of the classical benzodiazepine (BZD), diazepam …

A Comparision Of The Right And Left Hippocampus In Therabbit Brain In Terms Of Cell Density, Hayri Genç

Turkish Journal of Biology

The aim of this study was to investigate the structural asymmetry between the hemispheres by comparing the number of pyramidal cells in the right dorsal hippocampus with left dorsal hippocampus in the rabbit brain. Six adult domestic New Zeland rabbits were used in experiments. All animals were perfused intracardially with neutral formaline (10 %) under deep aneasthesia. The serial frontal sections were stained with thionin. The rostro-caudal level of these sections were determined by using a stereotaxic atlas of the rabbit brain. The number of pyramidal neurons was determined by counting identifiable neurons which had distict nucleus and nucleolus. The …