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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

1968

Rockefeller University

Articles 1 - 4 of 4

Full-Text Articles in Life Sciences

Corrections To The Debye-Huckel Theory, Thomas James Murphy Jan 1968

Corrections To The Debye-Huckel Theory, Thomas James Murphy

Student Theses and Dissertations

No abstract provided.


The Hydroxamate Reaction Of Aminoacyl-Trna Synthetases, David Ian Hirsch Jan 1968

The Hydroxamate Reaction Of Aminoacyl-Trna Synthetases, David Ian Hirsch

Student Theses and Dissertations

Amino acids are activated as aminoacyladenylates which remain bound to the aminoacyl-tRNA synthetases that catalyze their formation. The activated amino acids are then esterified to specific transfer RNA molecules. By this reaction sequence, the specificity and energetics necessary for polypeptide synthesis are conferred upon the amino acids. The first method of determining acyl group activation was the hydroxamate assay. The activated amino acids can be trapped as the stable amino acid hydroxamates by carrying out the activation reactions in high concentrations of hydroxylamine.


Mechanisms Of Target Discrimination By The Echolocating Bat, Vampyrum Spectrum, Jack Winningham Bradbury Jan 1968

Mechanisms Of Target Discrimination By The Echolocating Bat, Vampyrum Spectrum, Jack Winningham Bradbury

Student Theses and Dissertations

Five specimens, of the neotropical false-vampire bat, Vampyrum spectrum, were studied in an attempt to decide whether they were capable of discriminating between targets of differing shapes and sizes using echolocation alone. The study commenced with the demonstration that the bats could capture live mice, items similar to their normal prey, without recourse to visual or olfactory cues. The subsequent use of dead mice in place of live ones indicated that target identification was much more difficult for the bats when the mice were not moving, but could still be effected by some of them.


Phosphoproteins Of The Cell Nucleus: Metabolism And Characterization, Lewis Joel Kleinsmith Jan 1968

Phosphoproteins Of The Cell Nucleus: Metabolism And Characterization, Lewis Joel Kleinsmith

Student Theses and Dissertations

This thesis is concerned with the chemistry and metabolism of the phosphorylated proteins which are found localized in cell nuclei. The studies focus first on phosphoprotein metabolism as it occurs in the intact nucleus under varying conditions, and then on the chemistry and enzymology of a phosphoprotein fraction which has been extracted and purified from isolated nuclei. The metabolism of phosphoproteins was studied in isolated calf thymus nuclei employing P32 -orthophosphate as a tracer. These isolated nuclei incorporate this isotope into nuclear proteins, which yield phosphoserine and phosphothreonine on hydrolysis. Protein phosphorylation is energy dependent, and occurs after the …