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1997; Kansas Agricultural Experiment Station contribution; no. 98-100-S; Report of progress (Kansas Agricultural Experiment Station and Cooperative Extension Service); 792; Gonadotropin releasing hormone; Follicle stimulating hormone; Luteinizing hormone; Antibody; Immunization
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Full-Text Articles in Life Sciences
Development And Use Of Recombinant Gonadotropin-Releasing Hormone Vaccines To Sterilize Cattle: A Review (1997), J. Greer, Timothy G. Rozell
Development And Use Of Recombinant Gonadotropin-Releasing Hormone Vaccines To Sterilize Cattle: A Review (1997), J. Greer, Timothy G. Rozell
Kansas Agricultural Experiment Station Research Reports
A possible alternative to conventional castration methods is the use of vaccines that can be injected in order to sterilize animals. One promising approach involves the use of a vaccine that causes cattle to produce an immune response against one of their own reproductive hormones, gonadotropin releasing hormone (GnRH). Immunization against GnRH results in a decrease in the amount of GnRH circulating within the animal's blood. Therefore, follicle stimulating hormone (FSH) and luteinizing hormone (LH) are not stimulated to be released, and, subsequently their levels required for reproductive function. Experimentation has shown that immunization against GnRH can effectively block reproductive …