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The Impact Of Attenuated Porcine Reproductive And Respiratory Syndrome (Prrs) Vaccine On The Efficacy Of Subunit Classical Swine Fever Vaccine, R. Madera, L. Wang, A. G. Cino-Ozuna, J. Shi
The Impact Of Attenuated Porcine Reproductive And Respiratory Syndrome (Prrs) Vaccine On The Efficacy Of Subunit Classical Swine Fever Vaccine, R. Madera, L. Wang, A. G. Cino-Ozuna, J. Shi
Kansas Agricultural Experiment Station Research Reports
Commercial pigs have been routinely injected with multiple vaccines that are either administered separately or co-administered at the same time for convenience, and to minimize pig stress. However, viruses, including attenuated and modified live virus (MLV) vaccines, can modulate host immune responses that could potentially impact the efficacy of co-administered vaccines. Here we report the effects of pre- and co-administered Chinese highly pathogenic porcine reproductive and respiratory syndrome (PRRS) virus MLV, JXA1-R, on the efficacy of an emulsion-based classical swine fever virus (CSFV) subunit vaccine, KNB-E2. Immune responses to the CSFV and JXA1-R vaccines were evaluated by testing CSFV-specific and …
Genome Diversity And Molecular Detection Of Prrs Field Strains And Vaccine Strains, And Pcv3 And Pcv2 Strains, Y. Wang, F. Yuan, X. Liu, W. Zheng, H. Zhang, J. Zhang, K. Yoon, L. Peddireddi, Y. Fang, G. Anderson, J. Bai
Genome Diversity And Molecular Detection Of Prrs Field Strains And Vaccine Strains, And Pcv3 And Pcv2 Strains, Y. Wang, F. Yuan, X. Liu, W. Zheng, H. Zhang, J. Zhang, K. Yoon, L. Peddireddi, Y. Fang, G. Anderson, J. Bai
Kansas Agricultural Experiment Station Research Reports
Molecular diagnosis of porcine reproductive and respiratory syndrome virus (PRRS) and porcine circo virus (PCV) are challenging due to high genetic diversity in the viral genomes. Differentiating PRRS vaccine strains is even more challenging and is currently done by DNA sequencing, which is expensive and time-consuming. A multiplexed system (Luminex) allowing multiple detection targets in the same reaction is available. However, this system is not fully developed for common swine pathogens. Therefore, an assay was built to detect the majority of field PRRS strains by using different pairs of primers, and at the same time, to provide differentiation of the …