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Articles 1 - 30 of 237
Full-Text Articles in Life Sciences
Pvaast Anallysis Of Alzheimer’S Disease Sequencing Project Pedigree Data, Kristen Crofts, John S. K. Kauwe
Pvaast Anallysis Of Alzheimer’S Disease Sequencing Project Pedigree Data, Kristen Crofts, John S. K. Kauwe
Journal of Undergraduate Research
Alzheimer’s disease is a progressive brain disorder affecting more than 10 percent of Americans over the age of 65 (1). This disease destroys memory and thinking skills and is a leading cause of dementia. Although research in recent years has provided substantial information related to risk factors associated with Alzheimer’s disease, a great deal of information still remains unknown. PVAAST is a software tool that can analyze genome sequence data of Alzheimer’s patients in a creative way by also analyzing the patients’ pedigree information. With the combined information from family members, it is more feasible to identify genetic mutations related …
Literary Digest: Cannibal Poetry And Biology, Alicia Anzaldo, Claire Boeck, Sara Schupack
Literary Digest: Cannibal Poetry And Biology, Alicia Anzaldo, Claire Boeck, Sara Schupack
The STEAM Journal
A humanities professor and a biology professor at Wilbur Wright College collaborated to create a lesson on human digestion and poetry, enriching the humanities course theme on cannibalism. This article describes the lesson plan, examples of student work, and faculty reflections.
Heat And Mass Transfer Effects Of Peristaltic Transport Of A Nano Fluid In Peripheral Layer, K. M. Prasad, N. Subadra, M, A. S. Srinivas
Heat And Mass Transfer Effects Of Peristaltic Transport Of A Nano Fluid In Peripheral Layer, K. M. Prasad, N. Subadra, M, A. S. Srinivas
Applications and Applied Mathematics: An International Journal (AAM)
This paper deals with a theoretical investigation of heat and mass transfer effects of peristaltic transport of a nanofluid in peripheral layer. By using appropriate methods, the velocity in the core region as well as in the peripheral region, pressure drop, time averaged flux, frictional force, temperature profile, nanoparticle phenomenon, heat transfer coefficient and mass transfer coefficient of the fluid are investigated, using lubrication theory. Effects of different physical parameters like viscosity ratio, mean radius of the central layer, Brownian motion parameter, thermophoresis parameter, local temperature Grashof number as well as local nanoparticle Grashof number on pressure rise characteristics, frictional …
Bio Buzz Newsletter, Issue 14, November 2017, Department Of Biology
Bio Buzz Newsletter, Issue 14, November 2017, Department Of Biology
Biology Buzz Newsletter
Denison University, Department of Biology newsletter for Fall 2017.
Investigating X Chromosome Non-Disjunction In Drosophila Melanogaster Su(Var)3-9 Mutants, Camerun C. Washington, Kathryn Kohl
Investigating X Chromosome Non-Disjunction In Drosophila Melanogaster Su(Var)3-9 Mutants, Camerun C. Washington, Kathryn Kohl
The Winthrop McNair Research Bulletin
Meiotic recombination is a highly regulated process necessary for promoting proper chromosome disjunction during the first meiotic division. Notably, reduced levels of meiotic recombination are observed in heterochromatic regions of the chromosome. This study seeks to investigate the molecular mechanisms underlying this observation by examining the effects of reduced heterochromatin on non-disjunction rates in Drosophila melanogaster. To accomplish this, we measured non-disjunction in wild-type and reduced heterochromatin mutant su(var)3-9 flies. To begin, we confirmed the presence of a mutation within su(var)3-9 via Sanger sequencing. Next, we created allele-specific primers and designed a PCR protocol to more accurately identify mutant …
Targeted Mutagenesis Of Fox0 Transcripts Using The Model Organism Ciona Intestinalis Utilizing The Crispr/Cas9 System, Nicole Mcmullen, Heather J. Evans-Anderson
Targeted Mutagenesis Of Fox0 Transcripts Using The Model Organism Ciona Intestinalis Utilizing The Crispr/Cas9 System, Nicole Mcmullen, Heather J. Evans-Anderson
The Winthrop McNair Research Bulletin
The chordate, Ciona intestinalis, has become an excellent model organism for the study of cardiac development. C. intestinalis is a member of the phylum Tunicata, which is the sister phylum to vertebrates. Since both phyla share a common ancestor, an orthologous gene has been identified in C. intestinalis and vertebrates, the FOX0 transcript. Multiple reasons makes Ciona intestinalis an interesting model organism. For instance, ease of access to the animal, close relation to vertebrates, and mapping of the genetic code of Ciona intestinalis makes this an excellent model organism. The FOX0 family of transcripts plays an important role in …
Controlling Oct4 Expression Levels Using Invitrogen’S Geneswitch™ System, Autumn S. Leggins, Nick Grossoehme, Matthew M. Stern
Controlling Oct4 Expression Levels Using Invitrogen’S Geneswitch™ System, Autumn S. Leggins, Nick Grossoehme, Matthew M. Stern
The Winthrop McNair Research Bulletin
Oct4 is a protein that is involved in the retention of pluripotency in adipose derived stem cells (ADSCs). Despite this knowledge, Oct4’s exact role in the complex system used in maintaining pluripotency is not known. One approach to explore Oct4’s role would be through the use of cellular assays to control the expression of Oct4. This can possibly be accomplished by introducing a biological switch and the gene of interest into ADSCs. In this project, the GeneSwitch™ System is used to ultimately induce Oct4 expression. Before the GeneSwitch™ System can be used, the Oct4 gene is extracted from murine embryonic …
The Effect Of Concentration Of Co2 On The Average Rate Of Photosynthesis In Spinach Leaf Disks, Amelia Robinson-Brown
The Effect Of Concentration Of Co2 On The Average Rate Of Photosynthesis In Spinach Leaf Disks, Amelia Robinson-Brown
Journal of the South Carolina Academy of Science
The purpose of this experiment was to determine the effect of carbon dioxide concentration on the rate of photosynthesis in spinach leaves. Small circular disks were cut out of the spinach leaves using a standard hole puncher. Then solutions of differing concentrations of carbon dioxide, 0.2%, 0.4%, 0.6%, 0.8%, and 1.0%, were all prepared, and each solution was spread equally among five cups. There was also a control solution that contained only water. Any gases within the leaves were then sucked with a syringe, using a specific technique to create a vacuum. For each solution of differing carbon dioxide concentration, …
The Effects Of Tension, Curvature, And Lipid Diffusion On The Enrichment Of Ras Proteins In Model Membranes, Nina Daneshvar
The Effects Of Tension, Curvature, And Lipid Diffusion On The Enrichment Of Ras Proteins In Model Membranes, Nina Daneshvar
Journal of the South Carolina Academy of Science
An intriguing aspect of the cell membrane that provokes study is lipid-anchor enrichment of lipidated proteins on the cell membrane. Specifically, recent in vitro studies involving the enrichment of Ras proteins were done to see how enrichment was affected by changes in membrane curvature. These studies demonstrated the Ras protein’s inclination to the expanded, or outer, leaflet of highly curved membranes. Other research done in vivo, however, provoked further inquiry into Ras protein behavior, since when highly curved protrusions were created in living cells, Ras proteins showed affinity for the inner leaflet. This inspired research to determine the exact mechanism …
Novel Mosquito Control: A Natural Approach To Reducing And Repelling Mosquito Populations, Vinita Cheepurupalli
Novel Mosquito Control: A Natural Approach To Reducing And Repelling Mosquito Populations, Vinita Cheepurupalli
Journal of the South Carolina Academy of Science
Mosquitoes are a major concern to human health because they serve as vectors to pass agents that cause diseases, such as malaria, the Zika virus, and the West Nile virus, which can have a multitude of harmful side effects, such as seizures, conjunctivitis, and death. The overuse of commercial mosquitocidal agents have caused mosquitoes to develop resistance and cause harm to humans and the environment. To prevent this, natural extracts could be used. The purpose of this experiment was to test various plant extracts for their effectiveness in acting as larvicides, adulticides, and repellents against Culex quinquefasciatus mosquitoes. It was …
Promoting Critical Thinking In General Biology Courses: The Case Of The White Widow Spider, Joseph S. Wilson
Promoting Critical Thinking In General Biology Courses: The Case Of The White Widow Spider, Joseph S. Wilson
Journal on Empowering Teaching Excellence
It is generally accepted that critical thinking is an important and, likely, essential, component of success in college and beyond. Despite the unanimity, only a low percentage of students in the U.S. can demonstrate critical thinking proficiency on standardized exams. This phenomenon may result from instructors using a reductionist view of critical thinking and focusing on learning processes rather than on evaluation of intellectual resources. In general biology courses, I use a non-threatening, active-learning, group activities to promote critical thinking. For example, students are presented with an email from a member of the community and asked to formulate a response …
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
The Effects Of Sports Related Head Impact On Balance And Neurocognitive Functions, Shaquanda D. Ross-Simmons, Michelle L. Vieyra, Abhishek Jain, Keri Weed
The Effects Of Sports Related Head Impact On Balance And Neurocognitive Functions, Shaquanda D. Ross-Simmons, Michelle L. Vieyra, Abhishek Jain, Keri Weed
Journal of the South Carolina Academy of Science
The goal of this study was to investigate the effects of sports-related head injury on balance, attention, and memory. Reliable differences have been found using measures that directly tap into brain functioning, such as the auditory oddball task combined with EEG recording. We hypothesized that athletes reporting a diagnosed concussion or participation in high-risk sports would have compromised balance and neurocognitive functioning compared to athletes in low risk sports. Forty-five undergraduate participants were identified as either concussed, non-concussed in high-risk sports, or non-concussed in low-risk sports using a survey of athletic history, head trauma and demographics. The Biopac MP36 system, …
Investigating The Toxicity And Accumulation Of 2,4-Dichlorophenoxyacetic Acid (2,4-D) And Glyphosate In Eisenia Fetida, Caitlin Lazurick, Nicole Lidzbarski, Rachel Owings, Jeff Brotherton, Edna Steele
Investigating The Toxicity And Accumulation Of 2,4-Dichlorophenoxyacetic Acid (2,4-D) And Glyphosate In Eisenia Fetida, Caitlin Lazurick, Nicole Lidzbarski, Rachel Owings, Jeff Brotherton, Edna Steele
Journal of the South Carolina Academy of Science
Glyphosate, the main ingredient in Roundup®, is the most widely used herbicide in the world. It is also used in combination with another effective herbicide, 2,4-D, in the formulation called Enlist Duo®. The EPA approved the use of Enlist Duo® on certain crops including those genetically modified to be resistant to both herbicides. The predicted significant increase in the use of these herbicides raised concerns from the general public because both compounds have been classified as possibly or probably carcinogenic. Since herbicides are applied directly to vegetation, the safety of organisms that come in contact …
Investigation Of Moringa Oleifera Leaf Extract And Its Cancer-Selective Antiproliferative Properties, Reagen H. Welch, Ashlee H. Tietje
Investigation Of Moringa Oleifera Leaf Extract And Its Cancer-Selective Antiproliferative Properties, Reagen H. Welch, Ashlee H. Tietje
Journal of the South Carolina Academy of Science
Moringa oleifera is a tree native to a number of Asian, African, and Central American countries and has been used in traditional medicine for an assortment of medicinal uses for centuries. Due to bioactive compounds within Moringa leaves, it is believed that Moringa leaf extract may possess cancer-selective antiproliferative properties. Previous research has been conducted in regards to this topic, but poor experimental design due to lack of necessary controls limits the legitimacy of anticancer claims. While previous research has shown that Moringa leaf extract has the potential to kill cancer cells, the research fails to demonstrate the effects of …
Optimizing Sperm Collection Procedures In Zebrafish, Madelyn B. Wasden, Rachel L. Roberts, April Delaurier
Optimizing Sperm Collection Procedures In Zebrafish, Madelyn B. Wasden, Rachel L. Roberts, April Delaurier
Journal of the South Carolina Academy of Science
Zebrafish are a highly-valued model organism used for developmental biology research. Zebrafish can be used for genetic manipulation and hence, many mutant and transgenic lines exist. It is impractical to maintain lines of adult zebrafish, due to resource constraints and the need to continuously produce new generations. Therefore, a practical way to preserve zebrafish lines is to freeze sperm and retrieve lines using in vitro fertilization of fresh eggs. Most existing in vitro protocols used by research labs have a wide variety of fertilization rates (ranging from 0% to >90%). Due to this variability, lines may be at risk of …
Differences In Pragmatic Language Measures In Mothers Of Children With Autism Or Fragile X Syndrome, Michelle Huang
Differences In Pragmatic Language Measures In Mothers Of Children With Autism Or Fragile X Syndrome, Michelle Huang
Journal of the South Carolina Academy of Science
Mastery of pragmatics, which refers to the language used in different social interactions, is key to effective communication in daily life. However, studies have found that mothers of children with an autism spectrum disorder (ASD) or Fragile X Syndrome (FXS) are at an increased risk for impaired pragmatic language skills. Though many measures of pragmatic language exist for children, very few are available for these mothers. Two commonly used measures for the mothers include the Pragmatic Rating Scale (PRS) and the Pragmatic Language Subscale of the Broad Autism Phenotype Questionnaire (BAPQ). This study, unlike previous ones that only look at …
Big Data: Computational Biology Opens A New Window On The World's Challenges For Colby Scientists, Kate Carlisle
Big Data: Computational Biology Opens A New Window On The World's Challenges For Colby Scientists, Kate Carlisle
Colby Magazine
"What makes us 'us' and not a plant? Not a bacteria, or a virus," asks Andrea Tilden, the J. Warren Merrill Associate Professor of Biology and a genomics expert. "Any one genome has six thousand novels worth of information. Computational biology is the tool we use to read them."
Collaboration: Professor And Former Protégé Are Finding Answers To Nature's Questions, Gerry Boyle
Collaboration: Professor And Former Protégé Are Finding Answers To Nature's Questions, Gerry Boyle
Colby Magazine
Biologist Dave Angelini and collaborator Will Simmons '17J have published findings of their three-year study of the effect of pesticides on bumblebees and hope the results will have the scientific community looking for new solutions to the problem.
Science Phobic?: Professor Frank Fekete Can Fix That - And, Perhaps, Some Global Problems, Abukar Adan
Science Phobic?: Professor Frank Fekete Can Fix That - And, Perhaps, Some Global Problems, Abukar Adan
Colby Magazine
"It shouldn't be a surprise. Of any subdiscipline in biology, microbiology is the most relevant to my students' lives because everyone is concerned about his or her health." - Frank Fekete, professor of biology
Water Supply In Developing Countries: Student Experiences In The Dominican Republic, Albert Alwang, Margaret Busse, Audrey Caprio, Marieke Fenton, Jason Hawes, Andrew Kanach, Autumn Mcelfresh-Sutton
Water Supply In Developing Countries: Student Experiences In The Dominican Republic, Albert Alwang, Margaret Busse, Audrey Caprio, Marieke Fenton, Jason Hawes, Andrew Kanach, Autumn Mcelfresh-Sutton
Purdue Journal of Service-Learning and International Engagement
In 2010, the United Nations established access to safe drinking water as a basic human right; however, many areas around the globe still lack access. The interdisciplinary service-learning course “Water Supply in Developing Countries” was established at Purdue in 2012 to address the complex issue of water insecurity around the world. Over the past five years, the course has produced teams involving students from nursing, engineering, agricultural economics, biology, and food science working together to develop sustainable, community-scale drinking water treatment systems. In partnership with Aqua Clara International, the student team in 2017 established a drinking water treatment system at …
Modern Day Teleology, Brianna Cunningham
Modern Day Teleology, Brianna Cunningham
Quaerens Deum: The Liberty Undergraduate Journal for Philosophy of Religion
This paper seeks to explain a modern day universe theory derived from Teleology, namely: Intelligent Design, under which Irreducible Complexity and Fine-Tuning fall. By virtue of being derivatives of Teleology, both of these maintain the idea that things are evolving toward a certain end for a certain purpose. Through detailed definitions and examples, it is clear that these theories support each other; the astounding specificity needed for life on earth virtually requires an Intelligent Designer. The paper then explores counter explanations for this seeming impossibility, such as the Anthropic Principle Objection, Unique Universe, and the Multiverse. Each of these theories, …
The Beginning Of Archetypes: The End Of Chaos, Adam Stanley
The Beginning Of Archetypes: The End Of Chaos, Adam Stanley
Agora
No abstract provided.
New Record Of Asian Pied Starling (Gracupica Contra Contra) From Kalar Kahar (Pakistan), Usman Hanif, Fakhar-I- Abbas, Zahid Iqbal Khan, Afsar Mian
New Record Of Asian Pied Starling (Gracupica Contra Contra) From Kalar Kahar (Pakistan), Usman Hanif, Fakhar-I- Abbas, Zahid Iqbal Khan, Afsar Mian
Journal of Bioresource Management
A pair of Asian Pied Starling or Pied Myna (Gracupica contra contra) was sighted in reed vegetation present around Kalar Kahar Lake (northwestern Salt Range, Pakistan). Subspecies has been sighted for the first time west of Sialkot and Lahore. Further studies are required to determine the status of the population of the subspecies in Kalar Kahar to suggest an extension in distribution range of the species.
Seeds From Fresh Conventional Tomatoes Germinate Faster Than Dried Or Organic Seeds, Christopher G. Brown, Kautz Evan, Cameron Kilpatrick, Mary Vu, Mallory Weaver
Seeds From Fresh Conventional Tomatoes Germinate Faster Than Dried Or Organic Seeds, Christopher G. Brown, Kautz Evan, Cameron Kilpatrick, Mary Vu, Mallory Weaver
Georgia Journal of Science
Conventionally-grown and organically-grown tomato seeds sourced from both fresh tomatoes and store-bought packages were germinated for seven days to evaluate the effect of seed source on germination rates. Seeds from fresh Roma tomatoes were prepared by allowing them to ferment in their own pulp for 24 hours, while commercially packaged dry seeds did not require any preparation. Once prepared, the seeds were spaced evenly on wet paper towels and stored in resealable plastic bags in groups of 10 for a total sample size of 100 seeds in each of four treatments. The number of germinated seeds and the length of …
How Do Former Undergraduate Mentors Evaluate Their Mentoring Experience 3-Years Post-Mentoring: A Phenomenological Study, Kari L. Nelson, Christine E. Cutucache
How Do Former Undergraduate Mentors Evaluate Their Mentoring Experience 3-Years Post-Mentoring: A Phenomenological Study, Kari L. Nelson, Christine E. Cutucache
The Qualitative Report
This phenomenological study involves a unique, longitudinal assessment of the lived experiences of former undergraduate mentors (n=7) in light of their current experiences (i.e., career or advanced schooling). The objective of a phenomenological study is to engage in in-depth probing of a representative number of participants. Specifically, we followed up with graduates of the Nebraska STEM 4U (NE STEM 4U) intervention 3 years post-program, with the overall goal of describing the mentors’ experiences using the lens of their current experiences. This type of longitudinal perspective of mentoring is greatly lacking in the current literature. At the time of the interviews, …
The Mayfly Newsletter, Donna J. Giberson, Peter M. Grant
The Mayfly Newsletter, Donna J. Giberson, Peter M. Grant
The Mayfly Newsletter
No abstract provided.
Parts Of The Whole: Why I Teach This Subject This Way, Dorothy Wallace
Parts Of The Whole: Why I Teach This Subject This Way, Dorothy Wallace
Numeracy
The importance of mathematics to biology is illustrated by search data from Google Scholar. I argue that a pedagogical approach based on student research projects is likely to improve retention and foster critical thinking about mathematical modeling, as well as reinforce quantitative reasoning and the appreciation of calculus as a tool. The usual features of a course (e.g., the instructor, assessment, text, etc.) are shown to have very different purposes in a research-based course.
Byu Undergraduate Explore The Development Of Scientific Reasoning Ability In Stem Majors And Its Correlation To Student Performance And Retention, Jamie Jensen
Journal of Undergraduate Research
This report will outline how effectively we met our academic and mentoring objectives. I have listed below both the academic and mentoring objectives put forth in the original proposal and have outlined how they were met or modified over the course of the past two years. Let me just start out by saying how proud I am of my undergraduate team of researchers. They have been absolutely AMAZING and have taken this project on with incredible autonomy. Although we are a bit behind our anticipated schedule (due to the autonomy that I have tried to foster with the students), the …
Insect Visual Systems And Fossils To Provide Students A Clear Vision Of 21st Century Phylogenetic Systematics, Seth M. Bybee
Insect Visual Systems And Fossils To Provide Students A Clear Vision Of 21st Century Phylogenetic Systematics, Seth M. Bybee
Journal of Undergraduate Research
Goals one and three were both very successful (more below), however goal two became bogged down and was ultimately abandoned. CT-scanning is a process that requires hundreds or even thousands of fine x-rays through an organism in cross-section to be “stacked” together. Stacking the x-rays together allows researchers to literally explore the internal and external anatomy of organisms in ways never before possible. The most successful scans are those produced when tissues are discrete and have different attributes in terms of pattern, hardness, etc. We focused heavily on fossil specimens embedded in amber. Unfortunately, the cuticle of these specimens were …