Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 30 of 172

Full-Text Articles in Life Sciences

The Effect Of Various Polyphenols On Associative Memory Loss And Dementia In A Drosophila Melanogaster Model Of Alzheimer’S Disease, Anagha Gowda Jan 2024

The Effect Of Various Polyphenols On Associative Memory Loss And Dementia In A Drosophila Melanogaster Model Of Alzheimer’S Disease, Anagha Gowda

Journal of the South Carolina Academy of Science

Alzheimer’s Disease (AD), a prominent neurodegenerative disease (NDD), is the seventh leading cause of death in the United States; however, little is known about prevention. As a result, polyphenols (plant-based compounds) and other natural substances have been studied for their therapeutic potential in improving cognition and memory in AD cases. While the impacts of each polyphenol (phenolic acids, flavonoids, stilbenes, and lignans) contain fundamental similarities, each varies slightly in its impacts on the brain.The purpose of this study was to examine the impacts of polyphenol subgroups on associative memory in AD, tested by building an olfactory association, through the use …


The Comparative Impact Of Acesulfame-Potassium, Stevia Extract, And Monk Fruit On The Lifespan Of Drosophila Melanogaster, Beverly Holton Jan 2024

The Comparative Impact Of Acesulfame-Potassium, Stevia Extract, And Monk Fruit On The Lifespan Of Drosophila Melanogaster, Beverly Holton

Journal of the South Carolina Academy of Science

Non-nutritive sweeteners (NNS), non-caloric sweetening devices, have been widely commercialized to reduce sugar consumption. This intent has associated NNS with health benefits, though reports have correlated the consumption of these substitutes with noncommunicable diseases. The interaction between NNS and distinct physiological processes has been examined, though research into the broader implications of these interactions, toward longevity, for instance, is lacking. The purpose of this study was to compare the impact of three recently FDA-approved NNS - acesulfame-Potassium (ace-K), stevia, and monk fruit - on the survival of Drosophila melanogaster, a model species for longevity research, to discern the possible impacts …


The Effect Of Rosmarinus Officinalis And Trachyspermum Ammi On The Growth Of Eruca Vesicaria Ssp. Sativa In Hydroponics Versus Natural Soil, Emna Guedhami Jan 2024

The Effect Of Rosmarinus Officinalis And Trachyspermum Ammi On The Growth Of Eruca Vesicaria Ssp. Sativa In Hydroponics Versus Natural Soil, Emna Guedhami

Journal of the South Carolina Academy of Science

Despite technology being developed to address the food shortages due to increasing population, current methods of cultivating crops are not sufficient. Scientists are addressing this issue by researching biostimulants that stimulate plant growth without harming the environment and researching the use of hydroponics, a way of growing crops without soil. The purpose of this study was to combine the use of essential oils and growing methods (hydroponics and soil) and measure its impact on the height of E. sativa. It was hypothesized that if E. sativa was grown hydroponically with added Rosmarinus officinalis (REO) and Trachyspermum ammi (TEO) over time, …


The Effect Of Crystalline Phase On The Toxicity Of Tio2 Nanoparticles To Chlorella, Jisoo Lee Jan 2024

The Effect Of Crystalline Phase On The Toxicity Of Tio2 Nanoparticles To Chlorella, Jisoo Lee

Journal of the South Carolina Academy of Science

Nanoparticles (NPs), or particles with dimensions that go below 100 nanometers, can be released into the environment in various ways, such as through cosmetic products like sunscreen. Titanium dioxide (TiO2) is a commonly used nanoparticle in sunscreen, and it has the potential to be harmful to various aquatic organisms including algae. The purpose of this study was to examine how the crystalline phase of TiO2 NPs (brookite or rutile) influenced their toxicity to the microalgae species Chlorella. It was hypothesized that brookite phase TiO2 NPs would inhibit the growth of Chlorella more than rutile phase TiO …


The Combined And Individual Effects Of Azadirachta Indica L. Oil And Nahco3 On The Inhibition Of F. Oxysporum, Neya Murugesan Jan 2024

The Combined And Individual Effects Of Azadirachta Indica L. Oil And Nahco3 On The Inhibition Of F. Oxysporum, Neya Murugesan

Journal of the South Carolina Academy of Science

F. oxysporum is the causal agent of Fusarium wilt. This disease is known to penetrate the roots of plants and wilt the vascular system. The most common method for control is through the use of synthetic fungicides, which are known to cause adverse effects on the environment and human health. Thus, it is necessary that more methods of biocontrol be explored. Current literature shows that various salts and essential oils are effective for the biocontrol of F. oxysporum. However, the two types of substances have not yet been tested together, causing a gap in current research. Due to the antifungal …


The Effect Of The Addition Of Carrot Seed Oil And Raspberry Seed Oil On The Uv Intensity Of A Sunscreen, Isra Siddique Jan 2024

The Effect Of The Addition Of Carrot Seed Oil And Raspberry Seed Oil On The Uv Intensity Of A Sunscreen, Isra Siddique

Journal of the South Carolina Academy of Science

With continuous developments in research indicating the potential health risks of chemical sunscreen filters, the novel approach of incorporating natural oils with UV light blocking properties has been explored. Natural oils extracted from fruit and vegetables have been proven to possess photoprotective properties, but their effectiveness in combination with synthetic sunscreen filters has not been as thoroughly investigated. The purpose of this study was to determine whether the addition of carrot and raspberry seed oil to an SPF 30 sunscreen would decrease the UV intensity of UVB light passing through the sunscreen and oil mixture. It was hypothesized that if …


The Effect Of Exposure To Lentinula Edodes And Flammulina Velutipes On The Biodegradation Of Crystallized Polylactic Acid, Iraine Taine Jan 2024

The Effect Of Exposure To Lentinula Edodes And Flammulina Velutipes On The Biodegradation Of Crystallized Polylactic Acid, Iraine Taine

Journal of the South Carolina Academy of Science

Crystallized polylactic acid (CPLA) is a prevalent bioplastic which, despite being biodegradable, is extremely resistant to decomposition in natural environments. As a result, CPLA waste contamination is rapidly becoming a prevalent issue. Lentinula edodes and Flammulina velutipes are two widespread white-rot fungi whose capabilities for bioplastic degradation have not been examined. This study aimed to determine a natural approach for reducing plastic waste by evaluating the ability of L. edodes and F. velutipes to degrade CPLA bioplastic. It was hypothesized that CPLA samples would decrease in mass when individually treated with L. edodes and F. velutipes due to their similarities …


Table Of Contents Jan 2024

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Environmental Bacteriophage Presence In Drainage Ponds At Coastal Carolina University, Hailey Oldfield, Alexei E. Chesnutwood, Gabriella A. Caldwell, Shiraz C. Cohen, Paul E. Richardson Aug 2023

Environmental Bacteriophage Presence In Drainage Ponds At Coastal Carolina University, Hailey Oldfield, Alexei E. Chesnutwood, Gabriella A. Caldwell, Shiraz C. Cohen, Paul E. Richardson

Journal of the South Carolina Academy of Science

No abstract provided.


Developing A Safe And Effective Papillomavirus Screen To Be Used On College Students At A South Carolina University, Owen R. Smith, Nicole E. Frantz, Emily E. Bishop, Rahjai G. Thomas, Paul E. Richardson Aug 2023

Developing A Safe And Effective Papillomavirus Screen To Be Used On College Students At A South Carolina University, Owen R. Smith, Nicole E. Frantz, Emily E. Bishop, Rahjai G. Thomas, Paul E. Richardson

Journal of the South Carolina Academy of Science

No abstract provided.


Table Of Contents Aug 2023

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Consolidated Chamber Design And Protocol For Olfactory Conditioning Assay With Drosophila Melanogaster, Sasha Bronovitskiy, Andres Castillo, Michael Yan, Fang Ju Lin May 2023

Consolidated Chamber Design And Protocol For Olfactory Conditioning Assay With Drosophila Melanogaster, Sasha Bronovitskiy, Andres Castillo, Michael Yan, Fang Ju Lin

Journal of the South Carolina Academy of Science

The olfactory conditioning assay is widely used in Alzheimer’s disease research to quantify learning and memory in Drosophila melanogaster. The assay tests ability to recall an aversive conditioned stimulus of scent paired with electrical shock when presented a choice between shock-associated and unrelated scents. The T-maze, a commonly used apparatus for olfactory conditioning assays, employs an elevator mechanism to transfer live flies from the shock-delivering training chamber to the scent selection point. This elevator mechanism is known to cause fly casualty. T-mazes are not commercially available and often difficult to reproduce. Other existing variations of olfactory conditioning apparatuses use …


Table Of Contents May 2023

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


The Effects Of Salinity And Acetaminophen On The Aquatic Snail Physa Acuta, Michelle Sackey-Ansah, Megan Mackey, Daniel Elias, Jason Doll, Alyssa Brookhart Jan 2023

The Effects Of Salinity And Acetaminophen On The Aquatic Snail Physa Acuta, Michelle Sackey-Ansah, Megan Mackey, Daniel Elias, Jason Doll, Alyssa Brookhart

Journal of the South Carolina Academy of Science

Pharmaceuticals are increasingly detected in water bodies, and their presence can negatively impact aquatic organisms. This effect can be amplified when combined with increasing salinity in freshwater ecosystems. Acetaminophen is a widely used analgesic that is commonly found in river, streams, and waters where it is discharged directly. Therefore, organisms present in these locations (e.g., insects, snails, amphibians, and fish) are likely to be affected by acetaminophen. In this study, we determined the effects of elevated salinity (0.68 g/L), acetaminophen (500 µg/L) and combined elevated salinity (0.68 g/L) and acetaminophen (500 µg/L), on the growth, reproduction, and movement of the …


The Phytoremediation Of Escherichia Coli In Contaminated Water By Lemna Minor, Salvinia Minima, And Azolla Caroliniana, Madison Han Oct 2022

The Phytoremediation Of Escherichia Coli In Contaminated Water By Lemna Minor, Salvinia Minima, And Azolla Caroliniana, Madison Han

Journal of the South Carolina Academy of Science

No abstract provided.


The Effectiveness Of Lithium Chloride In Eliciting A Taste Aversion Response In Blaptica Dubia, Ava Phelps Oct 2022

The Effectiveness Of Lithium Chloride In Eliciting A Taste Aversion Response In Blaptica Dubia, Ava Phelps

Journal of the South Carolina Academy of Science

No abstract provided.


The Effect Of Spirulina Major And Oscillatoria On Reducing The Acidity Of Freshwater Containing Antibacterial Liquid And Bar Soaps ., Kartik Valluri Oct 2022

The Effect Of Spirulina Major And Oscillatoria On Reducing The Acidity Of Freshwater Containing Antibacterial Liquid And Bar Soaps ., Kartik Valluri

Journal of the South Carolina Academy of Science

No abstract provided.


The Effects Of Rice Bran Oil As A Repellent For Aedes Aegypti Compared To Mineral Oil And Effective Natural Repellents, Aleena Chattha Oct 2022

The Effects Of Rice Bran Oil As A Repellent For Aedes Aegypti Compared To Mineral Oil And Effective Natural Repellents, Aleena Chattha

Journal of the South Carolina Academy of Science

No abstract provided.


3,6-Dimethoxyxanthone From 2,2’,4,4’- Tetrahydroxy-Benzophenone Via Microwave-Assisted Annulation, Sarah E. Knisely, Faith R. Rosario, Salem F. Gebeyehu, Paige E. Heiple, Robert E. Lee Sr Oct 2022

3,6-Dimethoxyxanthone From 2,2’,4,4’- Tetrahydroxy-Benzophenone Via Microwave-Assisted Annulation, Sarah E. Knisely, Faith R. Rosario, Salem F. Gebeyehu, Paige E. Heiple, Robert E. Lee Sr

Journal of the South Carolina Academy of Science

Xanthones are tricyclic aromatic compounds that have multiple pharmacological uses due to their anti-tumor, antioxidant, anti-inflammatory, anti-bacterial, and potentially chemopreventive properties. The target of this research was to optimize a two-step synthesis of 3,6-dimethoxyxanthone (3) from 2,2’,4,4’-tetrahydroxy-benzophenone (1) via microwave-assisted (200 °C, 30-40 min., 150 W) sodium acetate-catalyzed annulation. The product, 3,6-dihydroxyxanthone (2), was then methylated to (3) using dimethyl sulfate (DMS) and sodium carbonate in acetone at reflux. The product yields were 93% (>99% purity) for (2) and 94% (>99% purity) for (3). Characterization was accomplished using 1H NMR, FTIR, melting point, TLC, HPLC, and GCMS. …


2022 Scas Annual Meeting Program And Bulletin Oct 2022

2022 Scas Annual Meeting Program And Bulletin

Journal of the South Carolina Academy of Science

No abstract provided.


Alu Dimorphism At The Pv92 Locus Of Chromosome 16 Is In Equilibrium For University Student Population, James M. Brooks, Mackenzie L. Thackston Oct 2022

Alu Dimorphism At The Pv92 Locus Of Chromosome 16 Is In Equilibrium For University Student Population, James M. Brooks, Mackenzie L. Thackston

Journal of the South Carolina Academy of Science

Alu is a retrotransposable element, which refers to its ability to be copied and move from one region of DNA to another DNA region. At the PV92 locus of chromosome 16, Alu is a 300 bp dimorphic insert that can either be present or absent. It does not encode a protein product and has lost the ability to transpose. It is specific to humans, and differences in genotype and allele frequencies between human populations are important tools in understanding evolution. In this research, data was obtained and analyzed from 269 students at Charleston Southern University (CSU) belonging to four different …


Environmental Bacteriophage Detection On Coastal Carolina University Campus, Madison Gentilo, Hailey Oldfield, Gavin Ockert, Paul E. Richardson Oct 2022

Environmental Bacteriophage Detection On Coastal Carolina University Campus, Madison Gentilo, Hailey Oldfield, Gavin Ockert, Paul E. Richardson

Journal of the South Carolina Academy of Science

Bacteriophages are viruses that infect bacteria. These viruses are found ubiquitously in the environment and are more abundant than any living organism on Earth, including bacteria. Eleven sites are designated for weekly sample collection on the campus of Coastal Carolina University. Water samples are filtered and amplified using strains of E. coli B and E. coli K12 to allow potential coliphages in the sample to proliferate to detectable levels. Plaque assays are used as a microbial screen for the presence of bacteriophage. Samples that test positively using the microbial test are analyzed through a molecular test using PCR to identify …


The Effects Of Human Behavioral Changes Due To The Covid-19 Pandemic On The Reservoir Of Lytic Escherichia Coli And Staphylococcus Aureus Bacteriophage On Humans At A South Carolina University, Korinne M. Swanson, Owen R. Smith, Paul E. Richardson Oct 2022

The Effects Of Human Behavioral Changes Due To The Covid-19 Pandemic On The Reservoir Of Lytic Escherichia Coli And Staphylococcus Aureus Bacteriophage On Humans At A South Carolina University, Korinne M. Swanson, Owen R. Smith, Paul E. Richardson

Journal of the South Carolina Academy of Science

Bacteriophages are viruses, whose unique ability to infect and lyse bacterial cells may provide valuable insight for evading the repercussions of a post-antibiotic era in medicine. This study isolated and characterized Escherichia coli and Staphylococcus aureus bacteriophage on students and faculty at Coastal Carolina University as a means to understand the viability of human bacteriophage reservoirs for bacteriophage therapy. From September 2021 to March 2022, nasal and postauricular swab samples and a behavioral survey were collected from ninety-three randomly selected participants. Additionally, sixteen participants contributed nasal and postauricular swab samples and a behavioral survey on a monthly basis in a …


Table Of Contents Oct 2022

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Table Of Contents Jun 2022

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Intramolecular Friedel-Crafts Addition Of Indoles To Tertiary Allylic Alcohols, Bryan H. Wakefield, Romie Barnes, Traeannah Brown, Ashley M. Jones, Victoria A. Knotts, Christina Martinetti Feb 2022

Intramolecular Friedel-Crafts Addition Of Indoles To Tertiary Allylic Alcohols, Bryan H. Wakefield, Romie Barnes, Traeannah Brown, Ashley M. Jones, Victoria A. Knotts, Christina Martinetti

Journal of the South Carolina Academy of Science

An intermolecular Friedel-Crafts alkylation of indole and tertiary allylic alcohols has been developed. The allylic alcohols were synthesized using a two-step procedure, then exposure of these alcohols to diphenyl phosphate facilitated the desired annulation reaction. This reaction tolerated a variety of indole substitutions to yield 1H,2H,3H,4H-pyrido[1,2-a]indoles.


The Effect Of Ayurvedic Plant Extracts-- Mucuna Pruriens And Brassica Oleracea--On The Delay Of Motor Symptoms In Pink1 Drosophila Melanogaster: A Model Of Parkinson's Disease, Sanjana Parise Aug 2021

The Effect Of Ayurvedic Plant Extracts-- Mucuna Pruriens And Brassica Oleracea--On The Delay Of Motor Symptoms In Pink1 Drosophila Melanogaster: A Model Of Parkinson's Disease, Sanjana Parise

Journal of the South Carolina Academy of Science

No abstract provided.


The Effect Of Qualitative Versus Quantitative Nutritional Education On The Eating Habits Of Female High School Athletes, Brantley Aycock Aug 2021

The Effect Of Qualitative Versus Quantitative Nutritional Education On The Eating Habits Of Female High School Athletes, Brantley Aycock

Journal of the South Carolina Academy of Science

No abstract provided.


The Mycoremediation Of Escherichia Coli By Pleurotus Ostreatus, Stropharia Rugosoannulata, And Trametes Versicolor In Contaminated Water, Madison Han Aug 2021

The Mycoremediation Of Escherichia Coli By Pleurotus Ostreatus, Stropharia Rugosoannulata, And Trametes Versicolor In Contaminated Water, Madison Han

Journal of the South Carolina Academy of Science

No abstract provided.


Sars-Cov-2: A Study Of The Dispersion Characteristics Of Aerosol Particles Using Ultrafast Carbon Nanotube Sensors In A Simulated Indoor Environment (A Novel Technique), Shriya Kapoor Aug 2021

Sars-Cov-2: A Study Of The Dispersion Characteristics Of Aerosol Particles Using Ultrafast Carbon Nanotube Sensors In A Simulated Indoor Environment (A Novel Technique), Shriya Kapoor

Journal of the South Carolina Academy of Science

No abstract provided.